Frontiers in digital health最新文献

{"title":"Digital health literacy-a key factor in realizing the value of digital transformation in healthcare.","authors":"Sarah Wamala Andersson, Marta Pisano Gonzalez","doi":"10.3389/fdgth.2025.1461342","DOIUrl":"10.3389/fdgth.2025.1461342","url":null,"abstract":"<p><strong>Background: </strong>Digital health technologies and AI are transforming healthcare by improving access, optimizing care, and enabling personalized, preventive, and predictive solutions. However, digital health literacy remains a critical barrier, affecting individuals' ability to engage with digital health technologies (DHTs) and limiting progress toward digital health equity.</p><p><strong>Aims: </strong>To propose a framework that captures the complexity of digital health literacy and guides research, and to share key insights from the Improving Digital Empowerment for Active Healthy Living EU project.</p><p><strong>Results: </strong>We introduce a conceptual framework that explores digital health literacy's interactions with social determinants, providing a foundation for research, policy, and practice. Insights from the project (Improving Digital Empowerment for Active Healthy Living), involving 14 partners across 10 European countries, offer evidence-based strategies to empower individuals and promote digital inclusion.</p><p><strong>Concluding remarks: </strong>To keep pace with technological advancements, digital health literacy should be integrated into lifelong learning initiatives. Urgent research is needed to inform policies and guide interventions that enhance digital health literacy and ensure equitable digital transformation in healthcare.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1461342"},"PeriodicalIF":3.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing digital health interventions with causal inference and multi-armed bandits: a review.","authors":"Radoslava Švihrová, Alvise Dei Rossi, Davide Marzorati, Athina Tzovara, Francesca Dalia Faraci","doi":"10.3389/fdgth.2025.1435917","DOIUrl":"10.3389/fdgth.2025.1435917","url":null,"abstract":"<p><p>Recent statistics from the World Health Organization show that non-communicable diseases account for 74% of global fatalities, with lifestyle playing a pivotal role in their development. Promoting healthier behaviors and targeting modifiable risk factors can significantly improve both life expectancy and quality of life. The widespread adoption of smartphones and wearable devices enables continuous, in-the-wild monitoring of daily habits, opening new opportunities for personalized, data-driven health interventions. This paper provides an overview of the advancements, challenges, and future directions in translating principles of lifestyle medicine and behavior change into AI-powered mobile health (mHealth) applications, with a focus on Just-In-Time Adaptive Interventions. Considerations for the design of adaptive interventions that leverage wearable and contextual data to dynamically personalize behavioral change strategies in real time are discussed. Bayesian multi-armed bandits from reinforcement learning are exploited as a framework for tailoring interventions, with causal inference methods used to incorporate structural assumptions about the user's behavior. Furthermore, strategies for evaluation at both individual and population levels are presented, with causal inference tools to further guide unbiased estimates. A running example of a simple real-world scenario aimed at increasing physical activity through digital interventions is used throughout the paper. With input from domain experts, the proposed approach is generalizable to a wide range of behavior change use cases.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1435917"},"PeriodicalIF":3.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital horizons in non-communicable disease care: a bibliometric exploration of intervention impact and innovation.","authors":"Sudip Bhattacharya, Alok Singh, Akanksha Kashyap","doi":"10.3389/fdgth.2025.1528711","DOIUrl":"10.3389/fdgth.2025.1528711","url":null,"abstract":"<p><strong>Introduction: </strong>Digital interventions show considerable promise in managing non-communicable diseases (NCDs) within primary healthcare.</p><p><strong>Aim: </strong>The aim of this study was to conduct a comprehensive bibliometric analysis of research on digital interventions for individuals living with NCDs.</p><p><strong>Methodology: </strong>This study explores digital interventions in NCDs through a bibliometric analysis from 2014 to 2024. Carefully designed search queries targeted primary and combined terms to cover a wide range of NCDs, including cancer, diabetes, and hypertension. SCOPUS searches yielded 9,572 English-language articles, refined by excluding non-relevant works and duplicates. Metadata, including authorship, keywords, and citations, was extracted for analysis. Using Biblioshiny and VosViewer, the study examined publication trends, telemedicine applications, and the knowledge framework of the field. Conceptual themes were identified through co-occurrence mapping, intellectual structures via co-citation networks, and social structures through collaboration patterns among authors, institutions, and countries.</p><p><strong>Results: </strong>The upward trend in research on digital interventions and NCDs accelerated significantly after 2018, peaking in 2021, followed by a slight decline. Medicine dominates this field, with considerable contributions from biochemistry, health professions, and engineering. The most prolific authors, primarily from the United States, United Kingdom, and Australia, have significantly shaped this research area. Institutional contributions are led by Harvard Medical School and other global leaders, reflecting strong inter-institutional collaborations. The United States and the United Kingdom are the most productive countries, with the Journal of Medical Internet Research standing out as the leading publication. Keyword analysis reveals a focus on telemedicine, COVID-19, tele-health, and digital health. Co-citation analyses identify key intellectual frameworks, while co-authorship and institutional collaborations highlight robust global networks. Emerging trends emphasize AI, digital health tools, and patient self-management, underscoring a transformative shift in addressing NCDs through technology-driven interventions. The findings highlight the need for patient-centered applications, improved implementation strategies, and strengthened collaborations, especially in underrepresented regions, to enhance the global impact of digital interventions for NCDs.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1528711"},"PeriodicalIF":3.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standards in sync: five principles to achieve semantic interoperability for TRUE research for healthcare.","authors":"Rhonda Facile, Catherine Chronaki, Peter van Reusel, Rebecca Kush","doi":"10.3389/fdgth.2025.1567624","DOIUrl":"10.3389/fdgth.2025.1567624","url":null,"abstract":"<p><p>The effective and meaningful exchange of data is pivotal for patient care, informed decision-making, and advancements in research and technology. This opinion piece explores the critical role of semantic interoperability (SI) in ensuring meaningful health data sharing across diverse systems. Emphasizing the imperative of synchronizing the use of data standards, we address the challenges posed by disparate data formats and underscore the impact on patient outcomes. International, harmonized standards are presented as a cornerstone for achieving SI, while the drawbacks of proprietary standards are examined. Case studies, including the complementary use of International Organization for Standardization (ISO), Health Level Seven Fast Healthcare Interoperability Resources (HL7 FHIR), and Clinical Data Interchange Standards Consortium (CDISC) standards, offer practical insights. We offer here five simple principles [reuse existing standards where possible, avoid mapping, implement standards at the start of a project, participate in standards development activities with standards development organizations (SDOs), and work toward harmonization of standards across SDOs] for achieving semantic meaning in support of Trustworthy, Reusable, Understandable data Elements (TRUE) research data for healthcare. We hope to provide a view to a future where standards are in sync and the proposed five principles are deployed globally to ensure the conduct of trustworthy research for the sake of improving health outcomes for all.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1567624"},"PeriodicalIF":3.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The development and use of data warehousing in clinical settings: a scoping review.","authors":"Shiyang Lyu, Simon Craig, Gerard O'Reilly, David Taniar","doi":"10.3389/fdgth.2025.1599514","DOIUrl":"10.3389/fdgth.2025.1599514","url":null,"abstract":"<p><strong>Introduction: </strong>The emergence of data warehousing in clinical settings has greatly enhanced data analysis capabilities, facilitating the accurate and comprehensive extraction of valuable information. This scoping review explores the contributions of data warehouses in clinical settings by analysing the strengths, challenges and implications of each type of data warehouse, with a particular focus on general and specialised types.</p><p><strong>Methods: </strong>This scoping review adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched four databases (PubMed, CINAHL, Scopus and IEEE-Xplore), identifying peer-reviewed, English-language studies from 1st January 2014 to 1st January 2024, that focus on data warehousing in healthcare, covering either general or specialised data warehouse applications. Python programming was used to extract the search results and transform the data into a tabular format for analysis.</p><p><strong>Results: </strong>After removing 1,194 duplicates, 4,864 unique papers remained. Abstract screening excluded 4,590 as irrelevant, leaving 274 for full-text evaluation. In total, 27 papers met the inclusion criteria, of which 17 focused on general data warehouses and 10 on specialised data warehouses.General data warehouses were found to be primarily used to address data integration issues, particularly for electronic health record (EHR)/ Electronic medical Record (EMR) and general clinical data. These warehouses typically use a star schema architecture with online analytical processing (OLAP) and query analysis capabilities. In contrast, specialised data warehouses were focused on improving the quality of decision support by handling a wide range of data specific to diseases, using specialised architectures and advanced artificial intelligence (AI) capabilities to address the unique and complex challenges associated with these tasks.</p><p><strong>Conclusions: </strong>General purpose data warehouses effectively integrate disparate data sources to provide a comprehensive view of disease management, patient care, and resource management. However, their flexibility and analytical capabilities need improvement. In contrast, specialised data warehouses are gaining popularity for their focus on specific diseases or research purposes, using advanced tools such as data mining and AI for superior analytical performance. Despite their innovative designs, these specialised warehouses face scalability challenges due to their customised nature. Addressing these challenges with advanced analytics and flexible architectures is critical.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1599514"},"PeriodicalIF":3.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging technologies transforming the future of global biosecurity.","authors":"Renan Chaves de Lima, Juarez Antonio Simões Quaresma","doi":"10.3389/fdgth.2025.1622123","DOIUrl":"10.3389/fdgth.2025.1622123","url":null,"abstract":"<p><p>The convergence of artificial intelligence and synthetic biology offers transformative opportunities to enhance global biosecurity. Emerging technologies promise rapid detection, containment, and mitigation of global biological threats, while simultaneously raising complex ethical and security challenges. This research aims to critically examine advances in AI applications for biosecurity, innovations in vaccine development enabled by synthetic biology, and the risks associated with the democratization of powerful biotechnological tools. We highlight both the potential and the dangers of integrating these technologies into public health preparedness systems and advocate for the establishment of robust governance frameworks to ensure their ethical and equitable implementation.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1622123"},"PeriodicalIF":3.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing usability and satisfaction of telephone-based psychiatry consultations in Oman: a cross-sectional study.","authors":"Tamadhir Al-Mahrouqi, Fatema Al-Sabahi, Mohammed Al-Alawi, Munira Al Rubkhi, Marwa Al Abdali, Muna Al Salmi, Tharaya Al-Hashemi, Rahma Al Nuumani, Fatma Al Balushi, Rashid Al Zaidi, Samir Al-Adawi, Sachin Jose, Hassan Mirza","doi":"10.3389/fdgth.2025.1563180","DOIUrl":"10.3389/fdgth.2025.1563180","url":null,"abstract":"<p><strong>Background: </strong>Telehealth has become a valuable tool for providing health services remotely through digital communication technologies. Therefore, assessing patients' satisfaction and the utility of this tool is crucial for future implementation and development.</p><p><strong>Methods: </strong>A cross-sectional survey study was conducted at Al Masarra Hospital between January 1st, 2023, and June 30th, 2023, with adults recruited from the general adult psychiatry clinic and received at least 3 previous telephone-based psychiatry consultations. Data were then analyzed using the Chi-square test and a multivariate binary logistic regression.</p><p><strong>Results: </strong>Among 222 patients (a mean age = 37.72 years), the majority (77.5%) were found to have an overall satisfaction with the service. Most participants agreed that telehealth improves access to healthcare services (65.2%), saves time traveling (78.4%), and meets their healthcare needs (75.7%). A total of 22.5% of participants reported dissatisfaction with the service. Significant predictors of satisfaction included sex, employment status, and monthly income. Females were more likely to be satisfied with telephone-based psychiatric consultations (Adjusted OR = 2.525, <i>p</i> = 0.030). Homemakers or unemployed participants were more likely to report satisfaction (Adjusted OR = 7.838, <i>p</i> = 0.009), as were those earning between 150 and 499 OMR (Adjusted OR = 10.967, <i>p</i> = 0.001) and ≥500 OMR (Adjusted OR = 46.312, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Telephone-based psychiatry consultations demonstrated high usability, satisfaction, and accessibility among study participants. Sex, employment status, and monthly income significantly influenced satisfaction levels. These findings highlight the potential of telehealth to bridge gaps in mental healthcare delivery, particularly for underserved populations in Oman. It is important to consider, however, the issues that might arise during these consultations that lead to dissatisfaction in some patients, and find suitable solutions for both the patients and the healthcare providers.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1563180"},"PeriodicalIF":3.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development, implementation and evaluation of a digital treatment for adolescents with chronic pain: a protocol for a multi-phase study.","authors":"Jordi Miró, Ariadna Sampietro, Sonia Monterde, Pablo Ingelmo, Rikard K Wicksell, Carme Nolla, Mercedes Alonso, Juan José Lázaro, Ernesto Martínez, Paloma Rubio, Armando Sánchez, Vanessa Sánchez, Alvaro Vázquez, Rocío de la Vega, Francisco Reinoso-Barbero","doi":"10.3389/fdgth.2025.1555733","DOIUrl":"10.3389/fdgth.2025.1555733","url":null,"abstract":"<p><p>Chronic pain in adolescents is an increasing public health concern with a significant physical, psychological, and social impact. This study aims to develop, implement, and evaluate DigiDOL-Ad, a digital psychosocial treatment for adolescents with chronic pain, supplemented by dedicated websites for their parents and teachers. This multicenter study will be conducted in four phases: (1) Development of the intervention framework and foundational planning; (2) Focus groups with adolescents with chronic pain, their parents, teachers, healthcare professionals and health authorities to identify specific needs and tailor the psychosocial treatment and related components; (3) Iterative usability testing of the digital treatment, using an a hermeneutical circle methodology to refine the design based on participant feedback; and (4) Evaluation of DigiDOL-Ad through a pre-treatment, post-treatment, and 3-month follow-up assessment. DigiDOL-Ad has the potential to improve the quality of life for adolescents with chronic pain. By leveraging digital health technologies, this innovative approach could establish a new benchmark for treating adolescents with chronic pain, emphasizing interdisciplinary and stakeholder-driven care.</p><p><strong>Clinical trial registration: </strong>clinicaltrials.gov, identifier NCT06765200.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1555733"},"PeriodicalIF":3.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Participatory design and evaluation of digital coaching for improving health-the star multicomponent lifestyle intervention.","authors":"Helena Lindgren, Kaan Kilic","doi":"10.3389/fdgth.2025.1600535","DOIUrl":"10.3389/fdgth.2025.1600535","url":null,"abstract":"<p><strong>Introduction: </strong>There are particular challenges when designing and developing a digital coaching application aimed at providing person-tailored support for lifestyle changes in multiple domains to promote health. This study explored how a participatory design process addresses challenges that materialised in a multicomponent lifestyle intervention, providing an understanding of the onboarding experience and early user engagement.</p><p><strong>Method: </strong>A participatory design methodology was applied involving a multidisciplinary team of 12 domain experts and different groups of end users in design cycles, model construction, prototyping, and evaluation. The process followed a design methodology for argument-based health information systems and a framework for layered interactive adaptive systems to engage domain experts in the development of aspects relating to the interactivity of the system. A qualitative user study was conducted with eight participants, five regular users and three nurses, focussing on the onboarding phase.</p><p><strong>Results: </strong>Contributions of this article are (i) the StarCoach, the person-tailored health-promotion intervention for multiple health behaviours supporting short and long-term goals; (ii) a framework for studying multicomponent lifestyle interventions with multiple behaviour change techniques (BCTs); and (iii) qualitative results regarding usage, adherence to, and perceived effects of the intervention with a focus on the initial phase of using the application. The five regular participants reported increased health-promoting activities during the onboarding phase and were using already habituated activities to establish a routine to use the intervention.</p><p><strong>Conclusion: </strong>The participatory design led to StarCoach embedding clusters of BCTs, which build a framework for research on multicomponent lifestyle interventions. Whether using already habituated activities to establish a routine to use the intervention could be a strategy to increase adherence and engagement in the onboarding phase and beyond will be a focus in future studies. The participants also showed increased engagement in their chosen lifestyle-change activities during the study period. The findings will be followed up in future studies to evaluate the effects on behaviour over a longer period of time.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1600535"},"PeriodicalIF":3.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12172075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pragmatic double blind remote pilot feasibility randomised controlled trial of a self-management app for people with Sjögren disease.","authors":"Katie L Hackett, Miglena Campbell, Eduwin Pakpahan, John Vines, Dennis Lendrem, Jemma McCready, Tim Rapley, Jason Ellis, Vincent Deary, Elaine McColl, Claire McCallum","doi":"10.3389/fdgth.2025.1549093","DOIUrl":"10.3389/fdgth.2025.1549093","url":null,"abstract":"<p><strong>Objectives: </strong>To pilot and assess the feasibility of a fully remote effectiveness evaluation of a novel smartphone self-management app for people living with Sjögren disease (SjD), including evaluating trial procedures and app engagement.</p><p><strong>Methods: </strong>We conducted a double-blind, randomised, fully-remote pilot feasibility of a self-management smartphone app (Sjogo) containing interactive components with an information-only control app. After completing onboarding procedures, participants were allocated to a trial arm following download from Apple App and Google Play stores. Participants completed symptoms and quality of life measures at baseline and (at two further timepoints (5-7 and 10-13 weeks) after download. Engagement with the app was measured with number and duration of logins.</p><p><strong>Results: </strong>996 participants downloaded Sjogo to their smartphone. 871 (87.45%) consented to take part in the study and 617 (61.95%) completed the onboarding procedures and baseline measures and were randomised to the full-version of the app (<i>n</i> = 318) or control-version (<i>n</i> = 299). In-app randomisation produced balanced groups. In week 1 engagement was higher in the intervention group <i>m</i> = 4.76 logins (S.D. 8.06) than the control group <i>m</i> = 3.47 (S.D. 2.75). At week 2 engagement dropped in both groups (intervention group <i>m</i> = 1.17, SD 4.56, control <i>m</i> = 0.40, SD 0.93). Outcome completion rates at subsequent timepoints were 36.63% (weeks 5-7) and 27.39% (weeks 10-13).</p><p><strong>Conclusion: </strong>It is feasible to collect data fully remotely, automate trial procedures, and recruit participants to a randomised controlled trial of a self-management smartphone app for people with SjD through app stores. However, app engagement and outcome completion rates could be improved.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"7 ","pages":"1549093"},"PeriodicalIF":3.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}