Meyke Roosink, Lisette van Gemert-Pijnen, Ruud Verdaasdonk, Saskia M Kelders
{"title":"Assessing health technology implementation during academic research and early-stage development: support tools for awareness and guidance: a review.","authors":"Meyke Roosink, Lisette van Gemert-Pijnen, Ruud Verdaasdonk, Saskia M Kelders","doi":"10.3389/fdgth.2024.1386998","DOIUrl":"10.3389/fdgth.2024.1386998","url":null,"abstract":"<p><p>For successful health technology innovation and implementation it is key to, in an early phase, understand the problem and whether a proposed innovation is the best way to solve the problem. This review performed an initial exploration of published tools that support innovators in academic research and early stage development with awareness and guidance along the end-to-end process of development, evaluation and implementation of health technology innovations. Tools were identified from scientific literature as well as in grey literature by non-systematic searches in public research databases and search engines, and based on expert referral. A total number of 14 tools were included. Tools were classified as either readiness level tool (<i>n</i> = 6), questionnaire/checklist tool (<i>n</i> = 5) or guidance tool (<i>n</i> = 3). A qualitative analysis of the tools identified 5 key domains, 5 innovation phases and 3 implementation principles. All tools were mapped for (partially) addressing the identified domains, phases, and principles. The present review provides awareness of available tools and of important aspects of health technology innovation and implementation (vs. non-technological or non-health related technological innovations). Considerations for tool selection include for example the purpose of use (awareness or guidance) and the type of health technology innovation. Considerations for novel tool development include the specific challenges in academic and early stage development settings, the translation of implementation to early innovation phases, and the importance of multi-disciplinary strategic decision-making. A remaining attention point for future studies is the validation and effectiveness of (self-assessment) tools, especially in the context of support preferences and available support alternatives.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1386998"},"PeriodicalIF":3.2,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennie S Lavine, Anthony D Scotina, Seth Haney, Jessie P Bakker, Elena S Izmailova, Larsson Omberg
{"title":"Impacts on study design when implementing digital measures in Parkinson's disease-modifying therapy trials.","authors":"Jennie S Lavine, Anthony D Scotina, Seth Haney, Jessie P Bakker, Elena S Izmailova, Larsson Omberg","doi":"10.3389/fdgth.2024.1430994","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1430994","url":null,"abstract":"<p><strong>Introduction: </strong>Parkinson's Disease affects over 8.5 million people and there are currently no medications approved to treat underlying disease. Clinical trials for disease modifying therapies (DMT) are hampered by a lack of sufficiently sensitive measures to detect treatment effect. Reliable digital assessments of motor function allow for frequent at-home measurements that may be able to sensitively detect disease progression.</p><p><strong>Methods: </strong>Here, we estimate the test-retest reliability of a suite of at-home motor measures derived from raw triaxial accelerometry data collected from 44 participants (21 with confirmed PD) and use the estimates to simulate digital measures in DMT trials. We consider three schedules of assessments and fit linear mixed models to the simulated data to determine whether a treatment effect can be detected.</p><p><strong>Results: </strong>We find at-home measures vary in reliability; many have ICCs as high as or higher than MDS-UPDRS part III total score. Compared with quarterly in-clinic assessments, frequent at-home measures reduce the sample size needed to detect a 30% reduction in disease progression from over 300 per study arm to 150 or less than 100 for bursts and evenly spaced at-home assessments, respectively. The results regarding superiority of at-home assessments for detecting change over time are robust to relaxing assumptions regarding the responsiveness to disease progression and variability in progression rates.</p><p><strong>Discussion: </strong>Overall, at-home measures have a favorable reliability profile for sensitive detection of treatment effects in DMT trials. Future work is needed to better understand the causes of variability in PD progression and identify the most appropriate statistical methods for effect detection.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1430994"},"PeriodicalIF":3.2,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Franceli L Cibrian, Elissa M Monteiro, Kimbelery D Lakes
{"title":"Digital assessments for children and adolescents with ADHD: a scoping review.","authors":"Franceli L Cibrian, Elissa M Monteiro, Kimbelery D Lakes","doi":"10.3389/fdgth.2024.1440701","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1440701","url":null,"abstract":"<p><strong>Introduction: </strong>In spite of rapid advances in evidence-based treatments for attention deficit hyperactivity disorder (ADHD), community access to rigorous gold-standard diagnostic assessments has lagged far behind due to barriers such as the costs and limited availability of comprehensive diagnostic evaluations. Digital assessment of attention and behavior has the potential to lead to scalable approaches that could be used to screen large numbers of children and/or increase access to high-quality, scalable diagnostic evaluations, especially if designed using user-centered participatory and ability-based frameworks. Current research on assessment has begun to take a user-centered approach by actively involving participants to ensure the development of assessments that meet the needs of users (e.g., clinicians, teachers, patients).</p><p><strong>Methods: </strong>The objective of this mapping review was to identify and categorize digital mental health assessments designed to aid in the initial diagnosis of ADHD as well as ongoing monitoring of symptoms following diagnosis.</p><p><strong>Results: </strong>Results suggested that the assessment tools currently described in the literature target both cognition and motor behaviors. These assessments were conducted using a variety of technological platforms, including telemedicine, wearables/sensors, the web, virtual reality, serious games, robots, and computer applications/software.</p><p><strong>Discussion: </strong>Although it is evident that there is growing interest in the design of digital assessment tools, research involving tools with the potential for widespread deployment is still in the early stages of development. As these and other tools are developed and evaluated, it is critical that researchers engage patients and key stakeholders early in the design process.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1440701"},"PeriodicalIF":3.2,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marc Blanchard, Vincenzo Venerito, Pedro Ming Azevedo, Thomas Hügle
{"title":"Generative AI-based knowledge graphs for the illustration and development of mHealth self-management content.","authors":"Marc Blanchard, Vincenzo Venerito, Pedro Ming Azevedo, Thomas Hügle","doi":"10.3389/fdgth.2024.1466211","DOIUrl":"10.3389/fdgth.2024.1466211","url":null,"abstract":"<p><strong>Background: </strong>Digital therapeutics (DTx) in the form of mobile health (mHealth) self-management programs have demonstrated effectiveness in reducing disease activity across various diseases, including fibromyalgia and arthritis. However, the content of online self-management programs varies widely, making them difficult to compare.</p><p><strong>Aim: </strong>This study aims to employ generative artificial intelligence (AI)-based knowledge graphs and network analysis to categorize and structure mHealth content at the example of a fibromyalgia self-management program.</p><p><strong>Methods: </strong>A multimodal mHealth online self-management program targeting fibromyalgia and post-viral fibromyalgia-like syndromes was developed. In addition to general content, the program was customized to address specific features and digital personas identified through hierarchical agglomerative clustering applied to a cohort of 202 patients with chronic musculoskeletal pain syndromes undergoing multimodal assessment. Text files consisting of 22,150 words divided into 24 modules were used as the input data. Two generative AI web applications, ChatGPT-4 (OpenAI) and Infranodus (Nodus Labs), were used to create knowledge graphs and perform text network analysis, including 3D visualization. A sentiment analysis of 129 patient feedback entries was performed.</p><p><strong>Results: </strong>The ChatGPT-generated knowledge graph model provided a simple visual overview with five primary edges: \"Mental health challenges\", \"Stress and its impact\", \"Immune system function\", \"Long COVID and fibromyalgia\" and \"Pain management and therapeutic approaches\". The 3D visualization provided a more complex knowledge graph, with the term \"pain\" appearing as the central edge, closely connecting with \"sleep\", \"body\", and \"stress\". Topical cluster analysis identified categories such as \"chronic pain management\", \"sleep hygiene\", \"immune system function\", \"cognitive therapy\", \"healthy eating\", \"emotional development\", \"fibromyalgia causes\", and \"deep relaxation\". Gap analysis highlighted missing links, such as between \"negative behavior\" and \"systemic inflammation\". Retro-engineering of the self-management program showed significant conceptual similarities between the knowledge graph and the original text analysis. Sentiment analysis of free text patient comments revealed that most relevant topics were addressed by the online program, with the exception of social contacts.</p><p><strong>Conclusion: </strong>Generative AI tools for text network analysis can effectively structure and illustrate DTx content. Knowledge graphs are valuable for increasing the transparency of self-management programs, developing new conceptual frameworks, and incorporating feedback loops.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1466211"},"PeriodicalIF":3.2,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11491428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deng Chen, ChengJie Lu, HongPeng Bai, Kaijian Xia, Meilian Zheng
{"title":"Integrating AI with medical industry chain data: enhancing clinical nutrition research through semantic knowledge graphs.","authors":"Deng Chen, ChengJie Lu, HongPeng Bai, Kaijian Xia, Meilian Zheng","doi":"10.3389/fdgth.2024.1439113","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1439113","url":null,"abstract":"<p><p>In clinical nutrition research, the medical industry chain generates a wealth of multidimensional spatial data across various formats, including text, images, and semi-structured tables. This data's inherent heterogeneity and diversity present significant challenges for processing and mining, which are further compounded by the data's diverse features, which are difficult to extract. To address these challenges, we propose an innovative integration of artificial intelligence (AI) with the medical industry chain data, focusing on constructing semantic knowledge graphs and extracting core features. These knowledge graphs are pivotal for efficiently acquiring insights from the vast and granular big data within the medical industry chain. Our study introduces the Clinical Feature Extraction Knowledge Mapping ( <math><mi>C</mi> <mi>F</mi> <mi>E</mi> <mi>K</mi> <mi>M</mi></math> ) model, designed to augment the attributes of medical industry chain knowledge graphs through an entity extraction method grounded in syntactic dependency rules. The <math><mi>C</mi> <mi>F</mi> <mi>E</mi> <mi>K</mi> <mi>M</mi></math> model is applied to real and large-scale datasets within the medical industry chain, demonstrating robust performance in relation extraction, data complementation, and feature extraction. It achieves superior results to several competitive baseline methods, highlighting its effectiveness in handling medical industry chain data complexities. By representing compact semantic knowledge in a structured knowledge graph, our model identifies knowledge gaps and enhances the decision-making process in clinical nutrition research.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1439113"},"PeriodicalIF":3.2,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam Meyers, Mertcan Daysalilar, Arman Dagal, Michael Wang, Onur Kutlu, Mehmet Akcin
{"title":"Quantifying the impact of surgical teams on each stage of the operating room process.","authors":"Adam Meyers, Mertcan Daysalilar, Arman Dagal, Michael Wang, Onur Kutlu, Mehmet Akcin","doi":"10.3389/fdgth.2024.1455477","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1455477","url":null,"abstract":"<p><strong>Introduction: </strong>Operating room (OR) efficiency is a key factor in determining surgical healthcare costs. To enable targeted changes for improving OR efficiency, a comprehensive quantification of the underlying sources of variability contributing to OR efficiency is needed. Previous literature has focused on select stages of the OR process or on aggregate process times influencing efficiency. This study proposes to analyze the OR process in more fine-grained stages to better localize and quantify the impact of important factors.</p><p><strong>Methods: </strong>Data spanning from 2019-2023 were obtained from a surgery center at a large academic hospital. Linear mixed models were developed to quantify the sources of variability in the OR process. The primary factors analyzed in this study included the primary surgeon, responsible anesthesia provider, primary circulating nurse, and procedure type. The OR process was segmented into eight stages that quantify eight process times, e.g., procedure duration and procedure start time delay. Model selection was performed to identify the key factors in each stage and to quantify variability.</p><p><strong>Results: </strong>Procedure type accounted for the most variability in three process times and for 44.2% and 45.5% of variability, respectively, in procedure duration and OR time (defined as the total time the patient spent in the OR). Primary surgeon, however, accounted for the most variability in five of the eight process times and accounted for as much as 21.1% of variability. The primary circulating nurse was also found to be significant for all eight process times.</p><p><strong>Discussion: </strong>The key findings of this study include the following. (1) It is crucial to segment the OR process into smaller, more homogeneous stages to more accurately assess the underlying sources of variability. (2) Variability in the aggregate quantity of OR time appears to mostly reflect the variability in procedure duration, which is a subinterval of OR time. (3) Primary surgeon has a larger effect on OR efficiency than previously reported in the literature and is an important factor throughout the entire OR process. (4) Primary circulating nurse is significant for all stages of the OR process, albeit their effect is small.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1455477"},"PeriodicalIF":3.2,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamshed Ali Shaikh, Chengliang Wang, Wajeeh Us Sima Muhammad, Muhammad Arshad, Muhammad Owais, Rana Othman Alnashwan, Samia Allaoua Chelloug, Mohammed Saleh Ali Muthanna
{"title":"RCLNet: an effective anomaly-based intrusion detection for securing the IoMT system.","authors":"Jamshed Ali Shaikh, Chengliang Wang, Wajeeh Us Sima Muhammad, Muhammad Arshad, Muhammad Owais, Rana Othman Alnashwan, Samia Allaoua Chelloug, Mohammed Saleh Ali Muthanna","doi":"10.3389/fdgth.2024.1467241","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1467241","url":null,"abstract":"<p><p>The Internet of Medical Things (IoMT) has revolutionized healthcare with remote patient monitoring and real-time diagnosis, but securing patient data remains a critical challenge due to sophisticated cyber threats and the sensitivity of medical information. Traditional machine learning methods struggle to capture the complex patterns in IoMT data, and conventional intrusion detection systems often fail to identify unknown attacks, leading to high false positive rates and compromised patient data security. To address these issues, we propose RCLNet, an effective Anomaly-based Intrusion Detection System (A-IDS) for IoMT. RCLNet employs a multi-faceted approach, including Random Forest (RF) for feature selection, the integration of Convolutional Neural Networks (CNN) and Long Short-Term Memory (LSTM) models to enhance pattern recognition, and a Self-Adaptive Attention Layer Mechanism (SAALM) designed specifically for the unique challenges of IoMT. Additionally, RCLNet utilizes focal loss (FL) to manage imbalanced data distributions, a common challenge in IoMT datasets. Evaluation using the WUSTL-EHMS-2020 healthcare dataset demonstrates that RCLNet outperforms recent state-of-the-art methods, achieving a remarkable accuracy of 99.78%, highlighting its potential to significantly improve the security and confidentiality of patient data in IoMT healthcare systems.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1467241"},"PeriodicalIF":3.2,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthias Klüglich, Bert Santy, Mihail Tanev, Kristian Hristov, Tsveta Mincheva
{"title":"Patient feasibility as a novel approach for integrating IRT and LCA statistical models into patient-centric qualitative data-a pilot study.","authors":"Matthias Klüglich, Bert Santy, Mihail Tanev, Kristian Hristov, Tsveta Mincheva","doi":"10.3389/fdgth.2024.1378497","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1378497","url":null,"abstract":"<p><strong>Introduction: </strong>Clinical research increasingly recognizes the role and value of patient-centric data incorporation in trial design, aiming for more relevant, feasible, and engaging studies for participating patients. Despite recognition, research on analytical models regarding qualitative patient data analysis has been insufficient.</p><p><strong>Aim: </strong>This pilot study aims to explore and demonstrate the analytical framework of the \"patient feasibility\" concept-a novel approach for integrating patient-centric data into clinical trial design using psychometric latent class analysis (LCA) and interval response theory (IRT) models.</p><p><strong>Methods: </strong>A qualitative survey was designed to capture the diverse experiences and attitudes of patients in an oncological indication. Results were subjected to content analysis and categorization as a preparatory phase of the study. The analytical phase further employed LCA and hybrid IRT models to discern distinct patient subgroups and characteristics related to patient feasibility.</p><p><strong>Results: </strong>LCA identified three latent classes each with distinct characteristics pertaining to a latent trait defined as patient feasibility. Covariate analyses further highlighted subgroup behaviors. In addition, IRT analyses using the two-parameter logistic model, generalized partial credit model, and nominal response model highlighted further distinct characteristics of the studied group. The results provided insights into perceived treatment challenges, logistic challenges, and limiting factors regarding the standard of care therapy and clinical trial attitudes.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1378497"},"PeriodicalIF":3.2,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Meenatchi Sundaram, Jayendra R Naik, Manikandan Natarajan, Aneesha Acharya K
{"title":"Design and development of an IoT-based trolley for weighing the patient in lying condition.","authors":"S Meenatchi Sundaram, Jayendra R Naik, Manikandan Natarajan, Aneesha Acharya K","doi":"10.3389/fdgth.2024.1339184","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1339184","url":null,"abstract":"<p><strong>Introduction: </strong>An immobile patient cannot be weighed on a stand-on weighing machine, i.e., a bathroom scale. They have to get weighed while lying, which is not easy. The main objective of this research is to design a medical apparatus that measures the patient's weight in a lying condition. To achieve this the apparatus is designed as a stretcher to carry the patient in and around the hospital.</p><p><strong>Methods: </strong>The stretcher has four load cells to measure the patient's weight; it can bear a weight of 500 kg and has a self-weight of 20 kg. A Microcontroller unit (MCU) is embedded into the apparatus to weigh the patient lying on it. The stretcher comprises the top frame, middle frame, and base frame. The top frame can be detached and mounted back to the middle frame; this will help the medical personnel shift the patients from a medical bed. The middle frame is a plate structure where the four load cells are mounted at the corners of the lower plate. The upper plate functions as a pressure plate on the load cell. The base plate has four heavy-duty wheels that can bear the load. The middle frame and base frame, together, form a single structure, giving mobility to the structure. A control panel is employed with reset, tare, and on-off buttons to control the embedded platform. The LCD panel on the side of the apparatus shows the weight when the patient is placed on top of the apparatus.</p><p><strong>Results and discussion: </strong>A prototype trolley equipped with a wireless data logging system was tested on 10 healthy participants. The device accurately measured weight within ±50 g across a scale range of 2-140 kg, with data captured every 30 s over a 5-min testing period. Wireless communication was successfully demonstrated over a 100-m range. The important add-on feature of this work is the apparatus is connected to the internet, transforming it into an IoT-based medical device.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1339184"},"PeriodicalIF":3.2,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11471732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed A Mahyoub, Kacie Dougherty, Ravi R Yadav, Raul Berio-Dorta, Ajit Shukla
{"title":"Development and validation of a machine learning model integrated with the clinical workflow for inpatient discharge date prediction.","authors":"Mohammed A Mahyoub, Kacie Dougherty, Ravi R Yadav, Raul Berio-Dorta, Ajit Shukla","doi":"10.3389/fdgth.2024.1455446","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1455446","url":null,"abstract":"<p><strong>Background: </strong>Discharge date prediction plays a crucial role in healthcare management, enabling efficient resource allocation and patient care planning. Accurate estimation of the discharge date can optimize hospital operations and facilitate better patient outcomes.</p><p><strong>Materials and methods: </strong>In this study, we employed a systematic approach to develop a discharge date prediction model. We collaborated closely with clinical experts to identify relevant data elements that contribute to the prediction accuracy. Feature engineering was used to extract predictive features from both structured and unstructured data sources. XGBoost, a powerful machine learning algorithm, was employed for the prediction task. Furthermore, the developed model was seamlessly integrated into a widely used Electronic Medical Record (EMR) system, ensuring practical usability.</p><p><strong>Results: </strong>The model achieved a performance surpassing baseline estimates by up to 35.68% in the F1-score. Post-deployment, the model demonstrated operational value by aligning with MS GMLOS and contributing to an 18.96% reduction in excess hospital days.</p><p><strong>Conclusions: </strong>Our findings highlight the effectiveness and potential value of the developed discharge date prediction model in clinical practice. By improving the accuracy of discharge date estimations, the model has the potential to enhance healthcare resource management and patient care planning. Additional research endeavors should prioritize the evaluation of the model's long-term applicability across diverse scenarios and the comprehensive analysis of its influence on patient outcomes.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":"6 ","pages":"1455446"},"PeriodicalIF":3.2,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11471729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}