Olga Osokina, Sanju Silwal, Minja Westerlund, Emmi Heinonen, Susanna Hinkka-Yli-Salomäki, Gennadiy Putyatin, Yuliia Yaschchyshyna, Norbert Skokauskas, Matthew Hodes, Andre Sourander
{"title":"Mental health consequences for adolescents during the Russian invasion of Ukraine: protocol for the Ukraine Adolescent Mental Health Study.","authors":"Olga Osokina, Sanju Silwal, Minja Westerlund, Emmi Heinonen, Susanna Hinkka-Yli-Salomäki, Gennadiy Putyatin, Yuliia Yaschchyshyna, Norbert Skokauskas, Matthew Hodes, Andre Sourander","doi":"10.3389/frcha.2025.1637011","DOIUrl":"10.3389/frcha.2025.1637011","url":null,"abstract":"<p><strong>Background: </strong>In February 2022, Russia launched a full scale-invasion of Ukraine, which is the largest European ground offensive since the Second World War. However, the Russian-Ukrainian war began in 2014, when Russia invaded and annexed the Crimea peninsula and occupied part of the eastern regions of Ukraine. This prolonged exposure to war, with its many casualties and massive displacement, has negatively affected the mental health of adolescents, although a comparison of the impacts on adolescents exposed to the various stages of war has not been documented. Our aim is to explore the effects of differential wartime traumatic stressor exposure and displacement on the mental health of adolescents exposed to the Russian invasion in Ukraine since 2014.</p><p><strong>Methods: </strong>The Ukraine Adolescent Mental Health Study (UAMS) is a time-trend study comprising two cross-sectional school surveys. The first survey was carried out in 2016-2017, two years after eastern Ukraine was invaded by Russia. The second survey was conducted after the 2022 full-scale Russian invasion. Both surveys used the same method and included participants aged 11-17 years from two areas in Ukraine, the Donetsk region and the Kirovograd region. In 2016-2017, we focused on adolescents living in the eastern Donetsk region who had been exposed to war since 2014 and those living in the central Kirovograd region, which was not directly affected by the invasion. The new survey will enable us to compare exposure to traumatic wartime stressors and mental health problems among adolescents over time and between the two regions. Several standardized tools will be used to assess post-traumatic stress disorder, depression, anxiety, suicidal ideation, suicide attempts and self-harm behavior.</p><p><strong>Discussion: </strong>This study will provide a unique opportunity to examine the escalating psychological consequences of the ongoing war on adolescents in Ukraine. Such information is crucial for understanding adolescents' mental health needs, and thus for providing psychosocial support and developing mental health interventions.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1637011"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12434108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lessa A Méndez-Lara, Rodrigo Ramirez-Rodriguez, Edgar Santos, Angel Puig-Lagunes
{"title":"Comparative analysis of stress levels and coping strategies in parents of neurodivergent and neurotypical children.","authors":"Lessa A Méndez-Lara, Rodrigo Ramirez-Rodriguez, Edgar Santos, Angel Puig-Lagunes","doi":"10.3389/frcha.2025.1619993","DOIUrl":"10.3389/frcha.2025.1619993","url":null,"abstract":"<p><p>Parents of children with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) face unique challenges that may significantly increase stress levels, potentially impacting the emotional well-being of the entire family. In Mexico, limited research has examined the association between parental stress and coping strategies among families with children with developmental disabilities. This study aimed to compare stress levels and coping strategies among parents of children with ASD, ADHD, and neurotypical developing (NTD) children, as well as to analyze differences in coping styles across these groups. A cross-sectional, descriptive-comparative design was employed with 212 parents of children aged 3 to 5 years, with a formal clinical diagnosis made by a pediatric neurologist. Participants completed validated questionnaires assessing parental stress and coping styles. Results revealed that parents of children with ASD and ADHD reported significantly higher stress levels (<i>M</i> = 116.7 and <i>M</i> = 88.1, respectively) compared to parents of NTD children (<i>M</i> = 67.2). Significant differences in coping strategies were observed (<i>p</i> < .001); 100% of ASD/ADHD parents used emotion-focused coping, whereas 94.93% of NTD parents used problem-focused coping. These findings emphasize the importance of designing interventions to support coping and stress regulation in parents of children with developmental disorders.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1619993"},"PeriodicalIF":0.0,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Framing chronic absenteeism and emotionally-based school absenteeism as public health problems.","authors":"Christopher A Kearney","doi":"10.3389/frcha.2025.1662093","DOIUrl":"10.3389/frcha.2025.1662093","url":null,"abstract":"<p><p>Chronic school absenteeism (CSA) and emotionally-based school absenteeism or avoidance (EBSA) are highly prevalent conditions linked to multiple short- and long-term problems across academic, social-emotional, physical and mental health, family, and occupational and economic domains of functioning. In addition, CSA and EBSA occur disproportionately across vulnerable student groups and have been the focus of extensive preventative and intervention efforts. As such, CSA and EBSA may meet criteria as formal public health problems. This perspective article illustrates various ways of framing CSA and EBSA in this fashion utilizing contemporary public health models. Categories of public health models are emphasized in this regard and include ecological, systems and policy, epidemiologic and statistical, environmental and occupational, and behavioral and social science approaches. Each approach closely parallels research and other work regarding school absenteeism. The article is designed as a step toward advocacy for recognizing CSA and EBSA as formal public health problems contingent upon consensus among key constituencies in this area.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1662093"},"PeriodicalIF":0.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faatima Ebrahim, Pamela Gretschel, Iesrafeel Abbas
{"title":"Striving to provide conditional access: strategies parents use to mediate the screentime of their children with autism spectrum disorder.","authors":"Faatima Ebrahim, Pamela Gretschel, Iesrafeel Abbas","doi":"10.3389/frcha.2025.1540147","DOIUrl":"10.3389/frcha.2025.1540147","url":null,"abstract":"<p><strong>Introduction: </strong>There has been a growing presence of screentime, in the lives of children, with an escalation in use during the COVID-19 pandemic restrictions. Children with autism spectrum disorder show a particular preference for engagement in screentime. Gaining parental understandings of the steps they take to mediate excessive screentime can assist in developing interventions which mitigate the well documented negative impacts of screentime for children with autism spectrum disorder. This paper presents the findings of a study which explored parental perceptions of the screentime use and the strategies parents used to manage the screentime engagement of their children with autism spectrum disorder.</p><p><strong>Methods: </strong>A qualitative descriptive design, using semi-structured, in-depth interviews with seven purposively selected parents, was used to achieve the above objectives. Data was thematically analysed using an inductive approach.</p><p><strong>Results: </strong>One of the four themes generated during the study; Striving to provide conditional access to screentime details the varied mediation strategies parents used to manage their child's screentime under the two categories of Content monitoring and Setting limits.</p><p><strong>Discussion: </strong>The findings of this study, describing the various restrictive strategies parents use to manage the screentime use of their children, were comparable to prior studies. Findings that built on existing evidence, describe the strategies parents used i.e., distraction and preparing for the cessation of screentime, to manage screentime in a way that avoided negative behaviour in their child and parental stress linked to this behaviour. It is certain, that screentime will remain a predominant occupation for children with autism spectrum disorder therefore, early childhood interventionists need to consider how to optimize the nature of engagement of screentime.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1540147"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145002031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth C Braithwaite, Esther Hargreaves, Jonathan Hill, Andrew Pickles, Helen Sharp, Nicky Wright
{"title":"Investigating sex differences in developmental origins of adolescent depression.","authors":"Elizabeth C Braithwaite, Esther Hargreaves, Jonathan Hill, Andrew Pickles, Helen Sharp, Nicky Wright","doi":"10.3389/frcha.2025.1602523","DOIUrl":"10.3389/frcha.2025.1602523","url":null,"abstract":"<p><strong>Introduction: </strong>Evolutionary hypotheses propose that fetuses show \"predictive adaptive\" responses to the prenatal environment based on likely continuity with the postnatal environment, and males and females have different adaptive priorities. Female adaptations appear to implicate hypothalamic-pituitary-adrenal (HPA) axis mechanisms moderated by early tactile stimulation. Based on these hypotheses we predict that lack of prenatal-postnatal environmental continuity (mismatch), will be associated with poorer outcomes in females, an effect that will be ameliorated by tactile stimulation. We previously reported that this prediction was supported by evidence from the Wirral Child Health and Development Study (WCHADS) of a three-way interaction between maternal prenatal anxiety, postnatal anxiety, and infant stroking in the prediction of irritability at age 7 years, seen only in girls. Here, we ask whether this effect persists over another 6 years into early adolescence.</p><p><strong>Methods: </strong>Mothers in a general population cohort (WCHADS) provided self-reported anxiety scores at 20 weeks of pregnancy, and at 9 weeks, 14 months and 3.5 years postpartum, and frequency of infant stroking at 9 weeks. Their children self-reported symptoms of depression in early adolescence at age 13 years. Structural equation modelling (SEM) with maximum-likelihood estimation was conducted using data from <i>N</i> = 695 mother-child dyads.</p><p><strong>Results: </strong>There was a three-way interaction between prenatal and postnatal anxiety and maternal stroking in the prediction of early adolescent depression, seen only in girls, consistent with our previous reports. When examining self-reported depression at age 13 years, increased stroking was associated with decreased symptoms of depression in girls in the mis-match group characterised by low prenatal and high postal anxiety, but not the high prenatal and low postnatal mis-match group.</p><p><strong>Discussion: </strong>We provide preliminary novel evidence that mechanisms likely to have evolved well before the emergence of humans, contribute to the risk of adolescent depression in girls. These findings have implications for understanding developmental origins of sex differences in adolescent depression.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1602523"},"PeriodicalIF":0.0,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martina Preisig, Isabelle Häberling, Lukasz Smigielski, Sophie Emery, Noemi Baumgartner, Mona Albermann, Michael Strumberger, Klaus Schmeck, Lars Wöckel, Suzanne Erb, Bruno Rhiner, Brigitte Contin-Waldvogel, Susanne Walitza, Gregor Berger
{"title":"The mediating role of depression in the association between health-related quality of life and suicidal ideation in adolescents: findings from a longitudinal study.","authors":"Martina Preisig, Isabelle Häberling, Lukasz Smigielski, Sophie Emery, Noemi Baumgartner, Mona Albermann, Michael Strumberger, Klaus Schmeck, Lars Wöckel, Suzanne Erb, Bruno Rhiner, Brigitte Contin-Waldvogel, Susanne Walitza, Gregor Berger","doi":"10.3389/frcha.2025.1567387","DOIUrl":"10.3389/frcha.2025.1567387","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescent suicidality is a significant public health issue. To develop effective interventions aimed at preventing suicide in this vulnerable population, it is essential to understand the complex interplay of health-related quality of life, depression and suicidal ideation.</p><p><strong>Methods: </strong>For this purpose, we analyzed longitudinal data of 250 children and adolescents diagnosed with major depressive disorder (M = 15.7, SD = 1.6, range 8-18 years, 74% females). The main goal of the study was to examine whether the effect of health-related quality of life on individual trajectories of suicidal ideation is mediated by depression severity. A series of t-tests, Chi-squared-tests, Fisher's exact tests and a mediation analysis including three robust linear mixed-effects models were conducted.</p><p><strong>Results: </strong>Depressed adolescents with suicidal ideation reported lower health-related quality of life across physical, psychological, peer, and school domains compared to those without suicidal ideation, while no significant difference was observed in the family-related domain. Psychological well-being emerged as the sole domain of health-related quality of life with a direct influence on suicidal ideation. Notably, depression severity mediated the effect of physical, psychological, peer- and school-related quality of life on suicidal ideation.</p><p><strong>Discussion: </strong>Our findings suggest that improving health-related quality of life reduces depressive symptoms, which in turn leads to lower suicidal ideation. This highlights the importance of including health-related quality of life in the clinical assessment of suicide risk as well as targeting health-related quality of life in therapeutic interventions. In the light of the results of this study, interventions should not only focus on classical clinical criteria of psychiatric diagnoses such as major depressive disorder, but also on broader, more resource-oriented constructs such as health-related quality of life to better mitigate the risk of suicide in this vulnerable population.</p><p><strong>Clinical trial registration: </strong>www.ClinicalTrials.gov, identifier [NCT03167307].</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1567387"},"PeriodicalIF":0.0,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12390987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and field test of the child and adolescent sleep checklist for parents of community junior high school students.","authors":"Kentaro Kawabe, Saori Inoue, Yu Matsumoto, Maya Kusunoki, Shu-Ichi Ueno, Yasunori Oka, Fumie Horiuchi","doi":"10.3389/frcha.2025.1644128","DOIUrl":"10.3389/frcha.2025.1644128","url":null,"abstract":"<p><strong>Aim: </strong>Children and adolescents get fewer than the recommended hours of sleep. The Child and Adolescent Sleep Checklist for parents (CASC-P) was designed to identify sleep habits and screen for sleep problems in junior high school students in Japan. This study aimed to validate the Japanese version of the CASC-P for junior high school students and determine its internal consistency.</p><p><strong>Methods: </strong>We used confirmatory factor analysis (CFA) and Cronbach's α to validate the scale and examine reliability. The analysis involved 218 parents of students aged 12-15 years.</p><p><strong>Results: </strong>Cronbach's α for the overall scale was 0.771. The prevalence of sleep problems was 15.6%. Factorial construct validity was assessed using the four-factor model used in the original CASC-P. Almost all items loaded meaningfully on their designated factors, and standardized factor-loading values ranged from 0.278 to 0.878 (except for items 1, 2, 9, 16, and 21).</p><p><strong>Conclusion: </strong>: The CASC-P is a suitable questionnaire for assessing parents' perspectives on adolescent sleep behavior.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1644128"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12378057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The price of possessiveness: how parental materialism undermines child psychological wellbeing.","authors":"Miao Li","doi":"10.3389/frcha.2025.1600599","DOIUrl":"10.3389/frcha.2025.1600599","url":null,"abstract":"<p><p>Materialism, a value system that places the pursuit of possessions at the core of happiness and life meaning, is a dominant cultural force in modern societies. While its associations with individual well-being are well-documented, its intergenerational implications remain understudied. This study conceptualizes materialism as a potential family stressor contributing to the intergenerational transmission of stress. An intergenerational crossover model of materialism was tested using data from 1,996 parent-child pairs in Zhengzhou, China. Results indicate that higher parental materialism is associated with stronger materialistic values in children, weaker family relationships, and more frequent parental comparisons, each of which is linked to greater psychological distress in youth. These patterns suggest that materialism may contribute to intergenerational patterns of vulnerability. The study highlights the cultural dimensions of mental health and provides a theoretical tool for further research on how materialism, as modernity's \"default value\", relates to health inequalities.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1600599"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Krause, Maria Rogers, Yuanyuan Jiang, Emma A Climie, Penny Corkum, Janet W T Mah, Natasha McBrearty, J David Smith, Jess Whitley
{"title":"A longitudinal investigation of school absenteeism and mental health challenges among Canadian children and youth in the COVID-19 context.","authors":"Amanda Krause, Maria Rogers, Yuanyuan Jiang, Emma A Climie, Penny Corkum, Janet W T Mah, Natasha McBrearty, J David Smith, Jess Whitley","doi":"10.3389/frcha.2025.1604431","DOIUrl":"10.3389/frcha.2025.1604431","url":null,"abstract":"<p><p>School absenteeism across the globe has risen dramatically since the COVID-19 pandemic. Literature indicates that children and youth of all ages are struggling to attend school regularly, leading to problematic outcomes both concurrently and across time. As well, research demonstrates that children and youth who experience mental health challenges are at greater risk of increased school absenteeism rates. The present study investigated the school attendance patterns of Canadian children and youth and the longitudinal and bidirectional links with mental health challenges within the COVID-19 pandemic context. The study sample consisted of 72 children and youth, using parent reports. Parents were asked to complete an online questionnaire which included questions about the demographic characteristics of themselves and their child, their child's school attendance patterns, and their child's mental health challenges. Preliminary descriptive statistics were run in relation to school absenteeism. Two separate path analyses were conducted to determine the longitudinal links between school absenteeism and mental health (split into externalizing and internalizing behaviours) across two timepoints (Time 1 [T1]: Fall 2022, Time 2 [T2]: Spring 2023). These analyses indicated concurrent links between mental health difficulties and school absenteeism. Importantly, path analyses also showed that absenteeism at T1 predicted poorer mental health at T2, indicating that school absenteeism may be one of the driving factors in the causal relationship. A bidirectional effect was found between externalizing behaviours at T1 and absenteeism rates at T2. The reasons for school absenteeism were examined across each time point and for both the externalizing and internalizing groups separately. The present study highlights the complex interplay between mental health and school absenteeism in the context of the COVID-19 pandemic. It provides avenues for effective intervention to better support children and youth struggling with mental health and school absenteeism.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1604431"},"PeriodicalIF":0.0,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction: Attachment, behavior problems and interventions.","authors":"Judy Hutchings, Margiad E Williams, Patty Leijten","doi":"10.3389/frcha.2025.1650383","DOIUrl":"https://doi.org/10.3389/frcha.2025.1650383","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/frcha.2023.1156407.].</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1650383"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}