Frontiers in child and adolescent psychiatry最新文献

{"title":"Transcranial photobiomodulation for reducing symptoms of autism spectrum disorder and modulating brain electrophysiology in children aged 2-7: an open label study.","authors":"Yuli Fradkin, Joaquin A Anguera, Alexander J Simon, Luis De Taboada, Eugenia Steingold","doi":"10.3389/frcha.2025.1477839","DOIUrl":"10.3389/frcha.2025.1477839","url":null,"abstract":"<p><strong>Background: </strong>Small pilot studies have indicated that transcranial photobiomodulation (tPBM) may help alleviate symptoms of neurological conditions like depression, traumatic brain injury and Autism Spectrum Disorder (ASD).</p><p><strong>Objective: </strong>To examine the effect of tPBM on the behavioral symptoms of ASD and brain electrophysiology in children aged 2-7.</p><p><strong>Methods: </strong>We conducted an open label, one-arm study with 23 participants, aged 2-7, previously diagnosed with ASD. We delivered non-invasively to all participants pulses of near-infrared light (wavelength 850 nm, pulse 40 Hz) to cortical nodes of Default Mode Network, Broca and Wernicke areas, and occipital lobe of the brain, twice weekly for 10 weeks. The tPBM was delivered using an investigational medical device designed for this purpose. Changes in ASD symptoms were measured using pre- and post-intervention scores on the Childhood Autism Rating Scale (CARS-2, 2nd Edition). We collected electroencephalogram (EEG) data after each treatment session from all children who tolerated wearing the EEG cap to monitor changes in brain activity.</p><p><strong>Results: </strong>The intervention resulted in a significant 7-point reduction in average CARS-2 scores (<i>t</i> = 10.23, <i>p</i> < .0001), along with decreased delta power and increased gamma and beta power in EEG readings. The increase in gamma power was statistically significant [<i>t</i>(14) = 2.30, <i>p</i> = 0.047]. Changes in EEG power were significantly correlated with the number of sessions (delta: <i>r</i>(192) = -0.18, <i>p</i> = .013; gamma: <i>r</i>(192) = .19, <i>p</i> = .007; beta: <i>r</i>(192) = .15, <i>p</i> = .04). Improvements in CARS-2 scores were negatively correlated with changes in delta and beta power (delta: <i>r</i>(15) = -.59, <i>p</i> = .020; beta: <i>r</i>(15) = -.54, <i>p</i> = .037). No moderate or severe side effects were reported.</p><p><strong>Conclusion: </strong>This study supports the potential of tPBM as a safe and effective treatment for ASD, and it suggests that EEG measurements may serve as a useful biomarker for future research.</p><p><strong>Trial registration: </strong>https://clinicaltrials.gov/ct2/show/NCT04660552.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1477839"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11814471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-design of the neurodevelopment assessment scale.","authors":"Tsz Ying Wong, Syeda Ishra Azim, Christa Lam-Cassettari, Ping-I Lin, Antonio Mendoza Diaz, Alicia Montgomery, Anne Masi, Kylie-Ann Mallitt, Andrew Whitehouse, Mark R Dadds, Valsamma Eapen","doi":"10.3389/frcha.2025.1497632","DOIUrl":"10.3389/frcha.2025.1497632","url":null,"abstract":"<p><strong>Introduction: </strong>Neurodevelopmental disorders (NDDs) have high comorbidity rates and shared etiology. Nevertheless, NDD assessment is diagnosis-driven and focuses on symptom profiles of individual disorders, which hinders diagnosis and treatment. There is also no evidence-based, standardized transdiagnostic approach currently available to provide a full clinical picture of individuals with NDDs. The pressing need for transdiagnostic assessment led to the development of the Neurodevelopment Assessment Scale (NAS).</p><p><strong>Methods: </strong>This paper describes the co-design process used in the development of NAS prototype with stakeholders including individuals with NDDs, parents of children with NDDs, and health professionals.</p><p><strong>Results and discussion: </strong>Results indicated stakeholder consensus that NAS would be useful for NDD assessment, and included recommendations for fine-tuning the way some questions were asked (e.g., child's diagnoses), question flow (e.g., branching logic), and the language and presentation of the prototype (e.g., readability). Stakeholders also suggested the administration protocol should be flexible using electronic, face-to-face, online formats etc.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1497632"},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: The role of parent-child interactions in developmental psychopathology: methodological and intervention challenges and opportunities.","authors":"R M Pearson, B Coetzee, T J Rochat","doi":"10.3389/frcha.2024.1489804","DOIUrl":"10.3389/frcha.2024.1489804","url":null,"abstract":"","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1489804"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ADHD help-seeking attitudes of Asian Americans.","authors":"Monisha Chawla, Jennalyn Vandenheuvel, Shannon L Sibbald","doi":"10.3389/frcha.2024.1491978","DOIUrl":"10.3389/frcha.2024.1491978","url":null,"abstract":"","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1491978"},"PeriodicalIF":0.0,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11798973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotion recognition deficits in children and adolescents with autism spectrum disorder: a comprehensive meta-analysis of accuracy and response time.","authors":"Maryam Masoomi, Mahdieh Saeidi, Rommy Cedeno, Zahra Shahrivar, Mehdi Tehrani-Doost, Zerimar Ramirez, Divya Aishwarya Gandi, Sasidhar Gunturu","doi":"10.3389/frcha.2024.1520854","DOIUrl":"10.3389/frcha.2024.1520854","url":null,"abstract":"<p><strong>Background: </strong>Autism spectrum disorder is a neurodevelopmental condition characterized by persistent challenges in social communication and restricted, repetitive behaviors. Emotion recognition deficits are a core feature of ASD, impairing social functioning and quality of life. This meta-analysis evaluates emotion recognition accuracy and response time in individuals with autism spectrum disorder compared to neurotypical individuals and those with other neurodevelopmental disorders.</p><p><strong>Methods: </strong>This systematic review with a meta-analysis was conducted following PRISMA guidelines. A comprehensive literature search across PubMed, Scopus, Cochrane Library, and Web of Science identified 13 studies published between 2006 and 2024. Data on emotion recognition accuracy and response times were synthesized using standardized mean differences in random-effects models. Heterogeneity was assessed using the <i>I</i> ² statistic, and sensitivity analyses were performed to ensure robustness.</p><p><strong>Results: </strong>Individuals with ASD exhibited significantly lower overall emotion recognition accuracy compared to TD individuals (SMD = -1.29, 95% CI: -2.20 to -0.39, <i>p</i> < 0.01) and NDDs (SMD = -0.89, 95% CI: -1.23 to -0.55, <i>p</i> = 0.02). Response times were significantly prolonged in ASD compared to TD individuals (SMD = 0.50, 95% CI: 0.36-0.63, <i>p</i> < 0.01) but not when compared to NDDs. Emotion-specific analyses did not consistently reveal significant differences across emotions (fear, anger, happiness, sadness, disgust, surprise), with substantial heterogeneity observed across studies (<i>I</i> ² > 50%).</p><p><strong>Conclusions: </strong>This systematic review with a meta-analysis highlights significant impairments in emotion recognition accuracy and processing speed among individuals with autism spectrum disorder, particularly compared to neurotypical individuals. These findings underscore the importance of developing targeted interventions to address these deficits, which are foundational to improving social cognition and quality of life in autism spectrum disorder. Future research should prioritize standardized methodologies and explore cultural and contextual factors influencing emotion recognition abilities.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=627339, PROSPERO (CRD42024627339).</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1520854"},"PeriodicalIF":0.0,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11772337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Regulatory problems and disorders in early childhood: aetiology, contextual factors, developmental outcomes and pathways, and treatment options.","authors":"Anna Katharina Georg, Julia Jaekel, Ayten Bilgin","doi":"10.3389/frcha.2024.1534024","DOIUrl":"https://doi.org/10.3389/frcha.2024.1534024","url":null,"abstract":"","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1534024"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PTSD, dysregulation profile and substance use: exploring differences in a sample of adolescents in an outpatient clinic.","authors":"Emely Reyentanz, Lukas A Basedow, Veit Roessner, Yulia Golub","doi":"10.3389/frcha.2024.1421486","DOIUrl":"10.3389/frcha.2024.1421486","url":null,"abstract":"<p><strong>Introduction: </strong>Experiencing traumatic events (TEs), especially interpersonal TEs, is related to an increased risk of developing post-traumatic stress disorder (PTSD). Both TEs and PTSD are associated with a higher risk of substance use and problems in emotion regulation. Little is known about the associations between specific types of TEs, problems with general self-regulation (including cognitive and behavioral components) and substance use severity in adolescents. Knowledge on these associations could provide important approaches for prevention and therapy for adolescents with a history of trauma.</p><p><strong>Methods: </strong>This study investigated associations between different types of TEs and PTSD, self-regulation and substance use severity. Moreover, participants were categorized into three groups according to their trauma status: (I) no history of TEs (noTEs), (II) history of TEs but no PTSD diagnosis (TEs), and (III) history of TEs and PTSD diagnosis (PTSD). Differences between the three groups were analyzed in terms of self-regulation and substance use severity. Our sample consisted of <i>N</i> = 89 adolescents aged 12 to 18 years in a child and adolescent psychiatric outpatient clinic in Germany. Substance use severity was only assessed in a smaller subsample (<i>n</i> = 37). Data were obtained from standardized diagnostic procedures and included information on types of TEs and PTSD diagnosis according to ICD-10, problems in self-regulation assessed with the Child Behavior Checklist (CBCL)/ Youth Self Report (YSR) Dysregulation Profile (DP), and substance use severity measured with the Drug Use Disorders Identification Test (DUDIT).</p><p><strong>Results: </strong>We found that interpersonal TEs were significantly associated with higher rates of PTSD diagnosis compared to non-interpersonal TEs. We found no significant associations between different types of TEs and both problems in self-regulation and substance use severity. Moreover, our findings do not indicate differences in both self-regulation and substance use severity between trauma statuses (noTEs, TEs, PTSD).</p><p><strong>Discussion: </strong>Future studies should consider other characteristics of TEs such as timing and duration when investigating associations with self-regulation. Longitudinal studies are needed to investigate developmental pathways, as a better understanding of the role of characteristics of TEs and self-regulation in the development of PTSD and substance use problems would provide opportunities for prevention and therapy for trauma-exposed patients.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1421486"},"PeriodicalIF":0.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity and its benefits on adolescents' mental health through self-esteem.","authors":"Catherine Laurier, Katherine Pascuzzo, Vicky Jubinville, Annie Lemieux","doi":"10.3389/frcha.2024.1503920","DOIUrl":"10.3389/frcha.2024.1503920","url":null,"abstract":"<p><strong>Background: </strong>Since the onset of the COVID-19 pandemic, the scientific community has been concerned about the high rates of psychological distress among adolescents. The pandemic not only tested adolescents' adaptation, but also disrupted key areas of their development. This demonstrates the need to study their psychological adjustment over time during this critical period to better guide services.</p><p><strong>Objective: </strong>This study sought to explore the extent to which physical activity and its association with self-esteem in the first months of the pandemic impacted adolescents' psychological distress, six months later.</p><p><strong>Methods: </strong>Two hundred and ninety-four adolescents (73% girls) between the ages of 12 and 17 participated in a longitudinal study launched at the start of the COVID-19 pandemic. The number of hours spent engaging in physical activity (HPA) in the past week and self-esteem were measured at Time 1 (T1; summer 2020). Psychological distress was measured at T1 and Time 2 (T2; winter 2021).</p><p><strong>Results: </strong>More HPA in the past week were related to greater self-esteem at T1. Greater self-esteem at T1 was related to lower psychological distress, six months later (T2). Lastly, HPA in the past week was not directly linked to psychological distress at T2, which confirms a fully indirect model.</p><p><strong>Conclusion: </strong>Results suggest that physical activity is a key factor in promoting better mental health adjustment through its benefits in terms of self-esteem, even during times of turmoil. Findings reinforce the recommendation of promoting the practice of sports and athletic activity in difficult times.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1503920"},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Early identification and prevention of suicidal crisis in children and young people.","authors":"Emma Ashworth, Saskia Mérelle, Pooja Saini","doi":"10.3389/frcha.2024.1507862","DOIUrl":"10.3389/frcha.2024.1507862","url":null,"abstract":"","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1507862"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"The package has been opened\"- parents' perspective and social validity of an Early Start Denver Model intervention for young children with autism.","authors":"Emilia Carlsson, Gudrun Nygren, Christopher Gillberg, Petra Linnsand","doi":"10.3389/frcha.2024.1509828","DOIUrl":"10.3389/frcha.2024.1509828","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to capture experiences and perspectives of parents of children with autism participating in an intervention program based on the Early Start Denver Model (ESDM). Specifically, we wanted their views regarding feasibility, acceptability, and significance of the intervention program, i.e., its social validity.</p><p><strong>Methods: </strong>Fourteen parents, whose children has been diagnosed with autism, were interviewed.</p><p><strong>Results: </strong>The results included three themes (1) <i>Comprehensive approach</i>: the participants emphasized the importance of early detection and interventions in their local setting in close cooperation between themselves, health care professionals, and preschool staff. They also highlighted the individual goals based on the child's needs in different developmental areas, as well as the whole family's needs and prioritizations. (2) <i>Hands on-available locally and accessible:</i> focused on different aspects of procedures, including features of the ESDM, parent education, the parent-therapist relationship and nearby location. (3) <i>Sense of empowerment-parents got increased knowledge:</i> the intervention was significant within family daily living and daily activities. The participants expressed that the interventions program contributed to an increased knowledge about autism and the ESDM strategies, positively impacted their child, and improved the collaboration with the preschool.</p><p><strong>Conclusion: </strong>Parents emphasized the naturalistic, comprehensive, and local setting of the intervention and described that they had gained new knowledge as well a sense of empowerment. The results indicated that the intervention program based on the ESDM was socially valid according to parent descriptions.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"3 ","pages":"1509828"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}