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The NNDC Road Map for Depression Care and Focused Areas of Research. NNDC抑郁症护理路线图和重点研究领域。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-04-15 DOI: 10.1176/appi.focus.25023008

引用次数: 0

Co-Occurring Bipolar and Substance Use Disorders: A Review of Impacts, Biopsychosocial Mechanisms, Assessment, and Treatment. 共发生双相情感障碍和物质使用障碍：影响、生物心理社会机制、评估和治疗的综述。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-04-15 DOI: 10.1176/appi.focus.20240044

Sarah H Sperry, Elizabeth T C Lippard

{"title":"Co-Occurring Bipolar and Substance Use Disorders: A Review of Impacts, Biopsychosocial Mechanisms, Assessment, and Treatment.","authors":"Sarah H Sperry, Elizabeth T C Lippard","doi":"10.1176/appi.focus.20240044","DOIUrl":"https://doi.org/10.1176/appi.focus.20240044","url":null,"abstract":"Individuals with bipolar disorder are at significant risk for having a co-occurring substance use disorder-particularly, alcohol and cannabis use disorders. Having a co-occurring substance use disorder is associated with a more pernicious clinical course, lower quality of life, and poorer treatment outcomes. Despite its increased morbidity, there is little research and clinical evidence-based guidelines on the treatment of individuals with co-occurring bipolar and substance use disorders. This review details current knowledge on the prevalence, clinical correlates, and biopsychosocial mechanisms underlying co-occurring bipolar and substance use disorders. The authors present recent research that highlights underlying mechanisms of comorbidity, including aberrant reward processing, stress sensitization, early childhood maltreatment, and gene-environment interactions. Next, the authors review current evidence-based recommendations for the assessment and treatment of co-occurring bipolar and substance use disorder, highlighting areas of needed future clinical research.","PeriodicalId":73036,"journal":{"name":"Focus (American Psychiatric Publishing)","volume":"23 2","pages":"173-182"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to Crowley, et al. (2024). 对Crowley等人（2024）的更正。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-03-03 DOI: 10.1176/appi.focus.20240017correction

引用次数: 0

Psychedelics for Depression: Between Hopes and Uncertainties. 抑郁症的致幻剂：介于希望和不确定性之间。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-04-15 DOI: 10.1176/appi.focus.20250005

Trisha Suppes, Mathieu Fradet

引用次数: 0

Anhedonia as a Core Symptom of Depression and a Construct for Biological Research. 快感缺乏是抑郁症的核心症状和生物学研究的一个概念。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-04-15 DOI: 10.1176/appi.focus.20240050

Majd Al-Soleiti, Jennifer L Vande Voort, Balwinder Singh

{"title":"Anhedonia as a Core Symptom of Depression and a Construct for Biological Research.","authors":"Majd Al-Soleiti, Jennifer L Vande Voort, Balwinder Singh","doi":"10.1176/appi.focus.20240050","DOIUrl":"https://doi.org/10.1176/appi.focus.20240050","url":null,"abstract":"Anhedonia is a key psychiatric symptom that has seen significant advances in its understanding in both clinical practice and research over the past few decades. Once considered primarily a feature of depression, recent studies have shown that anhedonia is also a core element of other psychiatric disorders and contributes to considerable morbidity, mortality, and suicidality. Emerging models of psychopathology and illness emphasize the transdiagnostic relevance of anhedonia. At the same time, neuroimaging research has provided deeper insights into its underlying pathophysiology, and several assessment scales with strong psychometric properties have been developed. Various treatment strategies-including psychopharmacology, neuromodulation, and psychotherapy-have demonstrated varying degrees of effectiveness. This review discusses the evolving understanding of anhedonia, its significance as both a symptom and a diagnostic marker, its prevalence, and its pathophysiological underpinnings. Additionally, the authors provide an overview of key assessment tools and explore the range of treatment approaches studied to date.","PeriodicalId":73036,"journal":{"name":"Focus (American Psychiatric Publishing)","volume":"23 2","pages":"163-172"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Road Map to Better Depression Care: A Road No Longer Less Traveled. 更好的抑郁症治疗路线图：一条不再少有人走过的路。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-04-15 DOI: 10.1176/appi.focus.20250007

Mark A Frye

引用次数: 0

Comorbid Cannabis Use and Mood Disorders Among Adolescents. 青少年共病性大麻使用和情绪障碍。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-04-15 DOI: 10.1176/appi.focus.20240049

Stephane J Strong, Halle A Thomas, Zachary W Adams, Leslie A Hulvershorn

引用次数: 0

Challenges and Opportunities in Using Cognitive Screeners for Adolescents and Young Adults With Bipolar Disorder. 在青少年和青年双相情感障碍患者中使用认知筛查的挑战和机遇。

Focus (American Psychiatric Publishing) Pub Date : 2025-04-01 Epub Date: 2025-04-15 DOI: 10.1176/appi.focus.20240045

Rebekah S Huber, Sally Weinstein, Aimee E Sullivan, Melissa M Batt, Jennifer Vande Voort, Melinda Westlund Schreiner, Funlola Are, Ioanna Douka, Melissa DelBello, Manpreet K Singh, Leslie Hulvershorn, Ramnarine Boodoo, Christopher J Hammond, James R Brasic, Neera Ghaziuddin, Richard Dopp, Leslie Miller

{"title":"Challenges and Opportunities in Using Cognitive Screeners for Adolescents and Young Adults With Bipolar Disorder.","authors":"Rebekah S Huber, Sally Weinstein, Aimee E Sullivan, Melissa M Batt, Jennifer Vande Voort, Melinda Westlund Schreiner, Funlola Are, Ioanna Douka, Melissa DelBello, Manpreet K Singh, Leslie Hulvershorn, Ramnarine Boodoo, Christopher J Hammond, James R Brasic, Neera Ghaziuddin, Richard Dopp, Leslie Miller","doi":"10.1176/appi.focus.20240045","DOIUrl":"https://doi.org/10.1176/appi.focus.20240045","url":null,"abstract":"Adolescents and young adults with bipolar disorder often experience cognitive deficits that hinder academic performance and social interactions, affecting long-term outcomes. Identifying cognitive impairments is crucial for improving clinical management of bipolar disorder. Use of cognitive screeners is recommended to identify cognitive difficulties and for ongoing assessment. Although cognitive screeners are effective with adults, their use with adolescents and young adults is limited. This project assessed clinicians' attitudes and practices regarding cognitive screening of adolescents and young adults with bipolar disorder. The National Network of Depression Centers (NNDC) Child and Adolescent Mood Disorders Task Group developed a survey for clinicians treating adolescents and young adults (ages 14-25) with bipolar disorder, evaluating their knowledge of and attitudes toward cognitive screening and barriers to implementation. A total of 163 clinicians across 23 NNDC sites completed the survey. Most recognized the impact of cognitive deficits on functioning (87%) and treatment response (76%). More than 90% reported that cognitive assessments would be beneficial; however, 78% were unaware of available tools, and 64% reported barriers to implementation. Findings highlight a need for clinician education and addressing barriers to implementation. This article outlines the importance of using screeners in treatment of adolescents and young adults with bipolar disorder and provides practical information for using screeners and recommendations for implementation.","PeriodicalId":73036,"journal":{"name":"Focus (American Psychiatric Publishing)","volume":"23 2","pages":"125-132"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to Lewis, et al. (2023). 对Lewis等人（2023）的更正。

Focus (American Psychiatric Publishing) Pub Date : 2025-01-01 Epub Date: 2024-12-13 DOI: 10.1176/appi.focus.20220088correction

引用次数: 0

Preventing Substance Use and Overdose Among Young Adults: The Role of Social Determinants of Health. 预防青少年使用药物和用药过量：健康的社会决定因素的作用》。

Focus (American Psychiatric Publishing) Pub Date : 2024-10-01 Epub Date: 2024-10-15 DOI: 10.1176/appi.focus.20240022

Christopher M Jones

引用次数: 0