European burn journal最新文献_第6页

Smart Polymeric Wound Dressing for Treating Partial-Thickness Burns: A Preliminary Preclinical Study on the Porcine Model. 用于治疗局部烧伤的智能聚合物伤口敷料：猪模型的初步临床前研究

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European burn journal Pub Date : 2023-01-15 DOI: 10.3390/ebj4010004

Dmitry Beylin, Josef Haik, Erik Biros, Rachel Kornhaber, Michelle Cleary, Moti Harats, Daniel Cohn, Yair Sapir, Ori Weisberg

{"title":"Smart Polymeric Wound Dressing for Treating Partial-Thickness Burns: A Preliminary Preclinical Study on the Porcine Model.","authors":"Dmitry Beylin, Josef Haik, Erik Biros, Rachel Kornhaber, Michelle Cleary, Moti Harats, Daniel Cohn, Yair Sapir, Ori Weisberg","doi":"10.3390/ebj4010004","DOIUrl":"10.3390/ebj4010004","url":null,"abstract":"Several so-called \"smart\" dressings are available for burn injuries to promote faster wound healing, and this technology has recently reported substantial advancements. However, the selection of an appropriate dressing for partial-thickness burns requires consideration of several crucial elements, including exudate management, conformability, antimicrobial properties, ease of application and removal, patient comfort, and cost-effectiveness. This preliminary feasibility study uses a porcine model to test the INTELIGELS product (Smart Bandage) for partial-thickness burns treatment. Artificially made wounds, mimicking partial-thickness burns, were assessed in two studies with and without antimicrobial additives, where wounds were randomly assigned to the experimental group treated with Smart Bandage and two control groups treated with a simple saline gauze dressing or Aquacel® products with and without silver additives. In addition, all dressings were evaluated for their ability to reduce wound size, quantified by histological analysis using punch biopsies. This study demonstrates comparable healing properties of Smart Bandage and Aquacel® dressings that are superior to the simple saline gauze dressing. The superiority is demonstrated by better regeneration, less inflammation of the epidermis and dermis, and better dermis remodeling with more granulation tissue maturation within the wound area when Smart Bandage/Aquacel® dressings are applied as compared with the simple gauze dressing.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"3 1","pages":"20-34"},"PeriodicalIF":1.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87916947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acknowledgment to the Reviewers of Eur. Burn J. in 2022. 致《欧洲烧伤杂志》审稿人的谢意Burn J. in 2022.

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European burn journal Pub Date : 2023-01-13 DOI: 10.3390/ebj4010003

Eur Burn J Editorial Office

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Analysis of Potential Risk Factors for Multidrug-Resistance at a Burn Unit. 烧伤科多重耐药性潜在风险因素分析

IF 1

European burn journal Pub Date : 2023-01-11 DOI: 10.3390/ebj4010002

Luís Cabral, Leonor Rodrigues, Ana H Tavares, Gonçalo Tomé, Marisa Caetano, Catarina Chaves, Vera Afreixo

{"title":"Analysis of Potential Risk Factors for Multidrug-Resistance at a Burn Unit.","authors":"Luís Cabral, Leonor Rodrigues, Ana H Tavares, Gonçalo Tomé, Marisa Caetano, Catarina Chaves, Vera Afreixo","doi":"10.3390/ebj4010002","DOIUrl":"10.3390/ebj4010002","url":null,"abstract":"Background: Infections by multidrug-resistant (MDR) microorganisms are associated with increased morbidity and mortality in burn patients. This study aimed to analyze the evolution of MDR bacteria over a five-year period at Coimbra Burns Unit (CBU) in Portugal, seeking to assess the possible associations of specific bacteria with presumed risk factors.Methods: The data obtained consisted of identified bacteria present in any microbiological sample from each patient (including blood, central venous catheter, urine, tracheal aspirate and/or wound exudate). Univariate models and a multivariate model were constructed for each of the MDR bacteria species that infected at least 50 patients or that had five or more MDR strains. Statistical hypothesis tests with a p-value less than 0.05 were considered significant.Results: Of a total of 341 samples obtained, 107 were MDR, corresponding to 10 species. Globally, there was no significant variation in MDR bacteria frequency over the period under analysis. Some risk factors and/or trends were identified for some species, but none was linked to all of them.Conclusions: The risks for the development of MDR in bacteria in burn patients are multifactorial, mainly linked to longer hospital stays, the use of invasive devices and inadequate antimicrobial treatment. However, the influence of these risks regarding specific bacterial species is not straightforward and may rely on individual characteristics, type of treatment and/or local prevalent flora. Due to the severity of multidrug-resistant infections, continued microbiological surveillance with the aid of rapid diagnostic tests and prompt institution of appropriate antimicrobial therapy are crucial to improving outcomes for burn patients.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"70 1","pages":"9-17"},"PeriodicalIF":1.0,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88810733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of COVID-19 on Burns: A Brazilian Study. COVID-19 对烧伤的影响：巴西的一项研究

IF 1

European burn journal Pub Date : 2022-12-28 DOI: 10.3390/ebj4010001

Carolina Moura, Marcela Bittencourt, Maria Luíza Cazumbá, Alexandra Buda, Alexis Bowder, Daniel Scott Corlew, Fábio Mendes Botelho Filho, Lucas Barboza, Laura Pompermaier

{"title":"The Impact of COVID-19 on Burns: A Brazilian Study.","authors":"Carolina Moura, Marcela Bittencourt, Maria Luíza Cazumbá, Alexandra Buda, Alexis Bowder, Daniel Scott Corlew, Fábio Mendes Botelho Filho, Lucas Barboza, Laura Pompermaier","doi":"10.3390/ebj4010001","DOIUrl":"10.3390/ebj4010001","url":null,"abstract":"During the COVID-19 pandemic, some of the strategies chosen to contain the spread, such as social isolation and use of alcohol-based hand sanitizer, were suspected to increase the risk of domestic accidents, especially burns. The aim of this study was, therefore, to investigate possible differences in epidemiological trends among burned patients admitted to the main referral hospital of the State of Minas Gerais, Brazil, before and during the pandemic.Methods: All categories of new burns admitted at the Burn Unit of the João XXIII Hospital in Belo Horizonte, Minas Gerais. The study group consisted of burn patients admitted between 1 March and 31 December 2020, and the control group consisted of those admitted between 1 March and 31 December 2019. The population was analyzed descriptively, and differences between patients admitted before and during the pandemic were tested using t-test, Wilcoxon Mann-Whitney Rank Sum test, the Chi-Squared test or Fisher's exact test, as appropriate.Results: During the study period, 914 patients were admitted at the burns unit, 535 before the pandemic (control group) and 379 during the pandemic (study group). During the pandemic, referral from other hospitals decreased, while time between injury and admission remained unchanged. TBSA% and LOS diminished, while the depth of burns, presence of inhalation injuries, and in-hospital mortality did not. In adults, the place and mechanism of injury changed during the pandemic, while in children they did not.Conclusion: Fewer patients with burns were referred for specialized burn care during the pandemic, although patients admitted for specialized burn care had smaller TBSA% and shorter LOS.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"63 1","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81651821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methoxyflurane for Relief of Procedural Pain in Burn Patients: A Prospective Single-Centre Evaluation Study. 缓解烧伤患者手术疼痛的甲氧氟烷：单中心前瞻性评估研究》。

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European burn journal Pub Date : 2022-11-30 DOI: 10.3390/ebj3040047

Andreas Creutzburg, Martin R Vestergaard, Pernille Pape, Caroline Hjelmdal, Filip Rangatchew, Rikke Holmgaard, Lars S Rasmussen

{"title":"Methoxyflurane for Relief of Procedural Pain in Burn Patients: A Prospective Single-Centre Evaluation Study.","authors":"Andreas Creutzburg, Martin R Vestergaard, Pernille Pape, Caroline Hjelmdal, Filip Rangatchew, Rikke Holmgaard, Lars S Rasmussen","doi":"10.3390/ebj3040047","DOIUrl":"10.3390/ebj3040047","url":null,"abstract":"Background: Procedural pain in burn patients continues to be a major problem. Frequently used analgesics, such as opioids, may have various side effects, including respiratory depression, nausea, and vomiting. Inhaled methoxyflurane has been used in the pre-hospital setting for trauma-related pain. This pilot study aimed to investigate the feasibility of using methoxyflurane for pain relief during dressings changes for burns in the hospital setting. Methods: In this investigator-initiated pilot study, we included burn patients undergoing dressing changes in the burn ward. The primary outcome was the maximal pain level experienced by the patient during the procedure on a verbal rating scale of 0 to 100. Furthermore, patient satisfaction and the nurse's assessment of the patient's pain were reported. We also reported the presence of nausea, vomiting, coughing, and headache, along with changes in the pulse rate, oxygen saturation, and arterial blood pressure. Results: We included 12 patients in the period of June 2021 to July 2022. The median patient-reported maximal procedural pain was 60 (interquartile range (IQR), 37-80), which corresponded well with the nurse's rating of a median of 57 (IQR 28-67). The patients were satisfied with methoxyflurane as an analgesic, with a median score of 96 (IQR 96-100). One patient reported coughing after the procedure, and another patient experienced nausea one week after the procedure. No clinically important haemodynamic changes during administration were detected. Conclusions: Methoxyflurane was found to be feasible for pain relief in burn patients undergoing dressing changes in the burn ward.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"2012 1","pages":"780-787"},"PeriodicalIF":1.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87856928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

19th European Burns Association Congress 第19届欧洲烧伤协会大会

European burn journal Pub Date : 2022-11-25 DOI: 10.1097/00006534-199012000-00096

N. Depetris, M. Stella

引用次数: 0

19th European Burns Association Congress. 第 19 届欧洲烧伤协会大会。

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European burn journal Pub Date : 2022-11-25 DOI: 10.3390/ebj3040046

Nadia Depetris, Maurizio Stella

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Biodegradable Temporising Matrix for Lower Limb Reconstruction following the Resection of Giant Marjolin's Ulcer. 用于巨型马若林溃疡切除术后下肢重建的生物可降解临时基质。

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European burn journal Pub Date : 2022-11-22 DOI: 10.3390/ebj3040045

Samuel MacDiarmid, Daniel Butler

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The Accuracy of Prehospital Fluid Resuscitation of Burn Patients: A Systematic Review. 烧伤患者院前液体复苏的准确性：系统回顾。

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European burn journal Pub Date : 2022-11-10 DOI: 10.3390/ebj3040044

Fahad Alsaqabi, Zubair Ahmed

{"title":"The Accuracy of Prehospital Fluid Resuscitation of Burn Patients: A Systematic Review.","authors":"Fahad Alsaqabi, Zubair Ahmed","doi":"10.3390/ebj3040044","DOIUrl":"10.3390/ebj3040044","url":null,"abstract":"Early management of burns is an essential component of achieving desirable patient outcomes. One of the earliest points of patient management in the case of burn injuries is in the prehospital setting. Unlike first aid, which can be provided by a non-healthcare worker, fluid resuscitation can be provided in the prehospital setting by emergency medical services personnel. This systematic review aims to investigate whether burn patients are receiving accurate fluid resuscitation in the prehospital setting. In addition, it will investigate if existing inaccuracies could impact patient outcomes negatively. This systematic review was completed in accordance with the guidelines from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The search for eligible studies started by searching relevant databases (PubMed, Embase, Medline, and Google Scholar). The selected studies were screened, and data were extracted and analyzed using a narrative synthesis approach. Seven studies met the inclusion criteria of this review, with a total of 961 patients. All seven studies included in this review reported that the volume of fluids for resuscitation purposes received by burn patients in the prehospital setting was inaccurate. However, most reported that the patient outcomes were not affected. Most of the studies were rated as \"good,\" however, and further high-quality randomized control studies are required before strong recommendations can be made.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"11 1","pages":"517-526"},"PeriodicalIF":1.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88792129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Administration Methods of Mesenchymal Stem Cells in the Treatment of Burn Wounds. 间充质干细胞治疗烧伤伤口的管理方法。

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European burn journal Pub Date : 2022-11-03 DOI: 10.3390/ebj3040043

Astrid Bjørke Jenssen, Samih Mohamed-Ahmed, Esko Kankuri, Ragnvald Ljones Brekke, Anne Berit Guttormsen, Bjørn Tore Gjertsen, Kamal Mustafa, Stian Kreken Almeland

{"title":"Administration Methods of Mesenchymal Stem Cells in the Treatment of Burn Wounds.","authors":"Astrid Bjørke Jenssen, Samih Mohamed-Ahmed, Esko Kankuri, Ragnvald Ljones Brekke, Anne Berit Guttormsen, Bjørn Tore Gjertsen, Kamal Mustafa, Stian Kreken Almeland","doi":"10.3390/ebj3040043","DOIUrl":"10.3390/ebj3040043","url":null,"abstract":"Cellular therapies for burn wound healing, including the administration of mesenchymal stem or stromal cells (MSCs), have shown promising results. This review aims to provide an overview of the current administration methods in preclinical and clinical studies of bone-marrow-, adipose-tissue-, and umbilical-cord-derived MSCs for treating burn wounds. Relevant studies were identified through a literature search in PubMed and Embase and subjected to inclusion and exclusion criteria for eligibility. Additional relevant studies were identified through a manual search of reference lists. A total of sixty-nine studies were included in this review. Of the included studies, only five had clinical data from patients, one was a prospective case-control, three were case reports, and one was a case series. Administration methods used were local injection (41% in preclinical and 40% in clinical studies), cell-seeded scaffolds (35% and 20%), topical application (17% and 60%), and systemic injection (1% and 0%). There was great heterogeneity between the studies regarding experimental models, administration methods, and cell dosages. Local injection was the most common administration method in animal studies, while topical application was used in most clinical reports. The best delivery method of MSCs in burn wounds is yet to be identified. Although the potential of MSC treatment for burn wounds is promising, future research should focus on examining the effect and scalability of such therapy in clinical trials.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"23 1","pages":"493-516"},"PeriodicalIF":1.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86515964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0