芬兰26年的皮肤银行。

IF 1 Q4 CRITICAL CARE MEDICINE
Kaarle Antila, Jyrki Vuola, Andrew Lindford
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引用次数: 0

摘要

自体皮肤移植是烧伤护理中最终伤口覆盖的金标准,但同种异体皮肤移植对于提供大面积烧伤的临时覆盖是必不可少的。赫尔辛基皮肤库成立于1995年,位于赫尔辛基烧伤中心,是芬兰唯一一家获得许可的皮肤库,为550万人口提供服务。它从大赫尔辛基地区的多器官捐赠者那里获得同种异体皮肤移植,并使用甘油保存它们,这是欧洲皮肤银行首创的一种方法。2009年至2020年期间,赫尔辛基皮肤银行从263名捐赠者那里获得皮肤,并为248名患者提供同种异体移植,主要是烧伤患者。随着时间的推移,采购方法有了显著的改进,导致每个捐赠者的皮肤采收量增加。尽管由于更严格的欧盟法规和24小时运营的需要,成本不断上升,但该银行仍然具有成本效益。甘油保存方法确保微生物安全和有效的储存,污染问题最小。未来可能会在皮肤替代品和干细胞治疗方面取得进展,但目前,同种异体皮肤仍然是烧伤护理的关键,因为它的可用性,易用性和成本效益。为一个烧伤中心经营一个小型的、专业的皮肤库已经被证明是成功的和可持续的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
26 Years of Skin Banking in Finland.

Autologous skin grafts are the gold standard for definitive wound coverage in burn care, but allograft skin grafts are essential for providing temporary coverage in cases of extensive burns. The Helsinki Skin Bank, established in 1995 at the Helsinki Burn Centre, is Finland's only licensed skin bank, serving a population of 5.5 million. It procures human skin allografts from multi-organ donors in the Greater Helsinki area and preserves them using glycerol, a method pioneered by the Euro Skin Bank. Between 2009 and 2020, the Helsinki Skin Bank procured skin from 263 donors and provided allografts to 248 patients, primarily burn victims. Over time, procurement methods have improved significantly, resulting in an increase in the amount of skin harvested per donor. Despite rising costs due to more stringent European Union regulations and the need for round-the-clock operations, the bank has remained cost-effective. The glycerol preservation method ensures microbiological safety and effective storage, with minimal contamination issues. The future may see advances in skin substitutes and stem cell treatments, but for now, allogenic skin remains crucial in burn care due to its availability, ease of use, and cost-efficiency. Running a small, professional skin bank for a single burn center has proven successful and sustainable.

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