Drug and alcohol dependence reports最新文献

{"title":"Help-seeking behaviours among cannabis consumers in Canada and the United States: Findings from the international cannabis policy study","authors":"Samantha M. Rundle,&nbsp;David Hammond","doi":"10.1016/j.dadr.2024.100306","DOIUrl":"10.1016/j.dadr.2024.100306","url":null,"abstract":"<div><h3>Background</h3><div>Little literature exists on what sources of help individuals utilize for cannabis-related problems. The current study examined the percentage of consumers who sought help to manage cannabis-related problems, such as perceived cannabis use disorder, the most common sources of help sought, and factors associated with help-seeking.</div></div><div><h3>Methods</h3><div>Past 12-month cannabis consumers (<em>N</em> = 13,209) completed an online survey from the International Cannabis Policy Study. Past 3-month help-seeking behaviours, respondent’s perceived addiction to cannabis, legal status of cannabis in their jurisdiction, and risky behaviours associated with cannabis use was assessed.</div></div><div><h3>Results</h3><div>A minority sought help from any source (9.2 %) with the most likely being a doctor/physician (44.9 %). Help-seekers were most likely to be younger, mixed race (<em>p</em> = .011), more educated, financially stable, male, and higher perceived addiction to cannabis (all contrasts <em>p</em> &lt; .001). In comparison to consumers in Canada and ‘legal’ US states, respondents in ‘illegal’ US states were more likely to seek help from family and friends (Canada: AOR = 5.73, 2.21–14.91; US: AOR = 4.76, 2.00–11.11) and less likely to seek help from a doctor/physician (Canada: AOR = 0.46, 0.24–0.90; US: AOR = 0.51, 0.27–0.99).</div></div><div><h3>Conclusion</h3><div>Roughly 1 in 10 cannabis consumers sought help from a range of sources, including a third who are at high risk of problematic use. More informal sources of help, such as seeking help from online sources are frequently used. Future research should examine these frontline sources of help for cannabis consumers.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100306"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse childhood experiences, resilience, and syringe services program attendance among persons who inject drugs in Northeast Georgia, USA: A mediation analysis","authors":"Mohammad Rifat Haider ,&nbsp;Samantha Clinton ,&nbsp;Monique J. Brown ,&nbsp;Nathan B. Hansen","doi":"10.1016/j.dadr.2024.100309","DOIUrl":"10.1016/j.dadr.2024.100309","url":null,"abstract":"<div><h3>Background</h3><div>Syringe services programs (SSP) are evidence-based venues offering harm reduction services to persons who inject drugs (PWID), such as sterile syringes, STI/HIV testing, and linkage to care to decrease drug use-related morbidities and mortalities. Adverse childhood experiences (ACEs) have been linked with reduced resilience, while increased resilience can help PWID attend SSPs. This study examined the potential mediating role of resilience between ACEs and SSP attendance among PWID.</div></div><div><h3>Methods</h3><div>Data were collected from adult HIV-negative PWID in northeast Georgia, between February-December 2023 (N = 173). Data were collected on SSP attendance (Yes vs. No), resilience, and ACEs. Covariates included age, gender, sexual orientation, race/ethnicity, education, homelessness, HIV risk behavior, syringe sharing, syringe use frequency, and primary drug. Path analysis was performed using Stata 18.0.</div></div><div><h3>Results</h3><div>The majority of PWID were cisgender men (68.8 %), heterosexual (92.5 %), homeless (93.6 %), had HIV risk behavior (65.9 %), had high resilience (54.3 %), and had never attended SSP (64.2 %). The mean number of ACEs was 4.1 (SD=3.2). After adjusting for covariates, high resilience was positively associated with SSP attendance (β= 0.204; p = 0.005). ACEs were negatively associated with high resilience (β= −0.035 p = 0.005) and SSP attendance (β= −0.026; p = 0.034). ACEs had a significant indirect effect on SSP attendance through high resilience (β= −0.007; p = 0.044).</div></div><div><h3>Conclusions</h3><div>Results indicate that resilience may mediate the relationship between ACEs and SSP attendance among PWID. It is important to develop and implement trauma-informed and resilience-based interventions to address the mental and sexual health challenges of PWID with a history of ACEs.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100309"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The feasibility of utilizing the open dynamic interaction network (ODIN) app to assess rEMA data across 30 days among those recovering from alcohol use disorders","authors":"Dennis E. McChargue ,&nbsp;Bilal Khan ,&nbsp;Jessica Phelps ,&nbsp;Patrick Duryea ,&nbsp;Kimberly A. Tyler ,&nbsp;Arthur Andrews ,&nbsp;Ellie Reznicek ,&nbsp;Lucy Napper ,&nbsp;Mohamed Saad ,&nbsp;Hsuan-Wei Lee","doi":"10.1016/j.dadr.2024.100305","DOIUrl":"10.1016/j.dadr.2024.100305","url":null,"abstract":"<div><div>Preliminary data from a prospective micro-longitudinal study (30 days) that examined the co-evolution of return to use risk among people diagnosed with an alcohol use disorder (AUD) in residential substance treatment is presented. Data assessed the feasibility of using the open dynamic interaction network (ODIN) responsive ecological momentary assessment (rEMA). rEMA collected daily estimates on affect, urges, sober-support engagement, and use. The ODIN app administered twelve daily questions at established EMA times. GPS-identified sober support engagement and alcohol access exposure prompted additional questions. Of the eight hundred questions, most people answered 500 questions. Five-day estimates showed that 80 % of the participants answered between 80 and 100 questions (10–30 questions/day). The ODIN app acquired 95 % of GPS readings across 30 days (~288 GPS readings/day). Most were satisfied with the stability (84 %), look/feel (82 %), and ease of use (92 %) of the ODIN app. Participants also reported interest in longer assessments that prompted them to call a sponsor (85 %) or to use prevention skills (72 %). Preliminary findings show that the ODIN platform accurately and efficiently collects data amongst this population.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100305"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11665290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabidiol prescribing in the United States: An analysis of real-world data","authors":"Binx Yezhe Lin ,&nbsp;Chloe Lessard ,&nbsp;Yifan Li ,&nbsp;Lisa Gong ,&nbsp;Ruth Ling ,&nbsp;Pallawi Jyotsana ,&nbsp;Jacob Steinle ,&nbsp;Jacob T. Borodovsky ,&nbsp;Fábio A. Nascimento ,&nbsp;Kevin Y. Xu","doi":"10.1016/j.dadr.2024.100303","DOIUrl":"10.1016/j.dadr.2024.100303","url":null,"abstract":"<div><h3>Background</h3><div>Off-label prescribing of Epidiolex® (pharmaceutical cannabidiol) comes with both potential benefits and risks for patients. The aims of this study were to: (1) identify the percentage of people prescribed Epidiolex® who do not have diagnostic indications for Epidiolex® (Lennox Gastaut Syndrome [LGS], Dravet Syndrome [DS], and Tuberous Sclerosis Complex [TSC]) and (2) examine potential co-prescribing of medications that may interact with Epidiolex®.</div></div><div><h3>Method</h3><div>Using TriNetX analytics, a web-based database of de-identified electronic health records spanning &gt;110 million people in the United States, we analyzed 4214 people receiving Epidiolex® in 2022. We computed the number of people prescribed Epidiolex® who did not have diagnoses for LGS, DS, or TSC. We evaluated the prevalence of co-occurring prescriptions that are known to interact with cannabidiol following each individual’s first Epidiolex® prescription.</div></div><div><h3>Results</h3><div>Among individuals receiving Epidiolex®, 40 % did not have FDA-approved diagnostic indications (LGS/DS/TSC) in the medical record. In the overall sample, co-occurring psychotropic prescribing was prevalent, including medications with known interactions with cannabidiol (Clobazam=47.2 %; Diazepam=47.4 %; Clonazepam=40.7 %). Among individuals without LGS/DS/TSC who received Epidiolex®, the most common diagnoses received following the index prescription were unspecified epileptic syndromes (53.8 %), sleep disorders (25.7 %), anxiety disorders (25.9 %), mood disorders (18.6 %) and autism spectrum disorders (10.8 %).</div></div><div><h3>Conclusion</h3><div>Off-label prescribing and co-prescription of medications with known interactions with cannabidiol is prevalent. Further research is needed to elucidate longitudinal outcomes associated with off-label Epidiolex® prescribing.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"13 ","pages":"Article 100303"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142722044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase 1b/2a safety study of lemborexant as an adjunctive treatment for insomnia to buprenorphine-naloxone for opioid use disorder: A randomized controlled trial","authors":"Caitlin E. Martin ,&nbsp;James M. Bjork ,&nbsp;Lori Keyser-Marcus ,&nbsp;Roy T. Sabo ,&nbsp;Tiffany Pignatello ,&nbsp;Kameron Simmons ,&nbsp;Christina La Rosa ,&nbsp;Albert J. Arias ,&nbsp;Tatiana Ramey ,&nbsp;F. Gerard Moeller","doi":"10.1016/j.dadr.2024.100304","DOIUrl":"10.1016/j.dadr.2024.100304","url":null,"abstract":"<div><h3>Background</h3><div>Evidence supports the common incidence of sleep disturbance in opioid use disorder (OUD) as a potential marker of disrupted orexin system functioning. This study evaluated the initial safety and tolerability of a challenge dose of lemborexant, a dual orexin antagonist, as an adjunct to buprenorphine/naloxone.</div></div><div><h3>Methods</h3><div>Patients (18–65 years old) with OUD receiving sublingual buprenorphine/naloxone, with a Pittsburgh Sleep Quality Index total score of 6 or higher, were recruited from outpatient clinics. After randomization, while being monitored on an inpatient research unit over two 10-hour daytime periods, participants received a placebo or lemborexant (5<!--> <!-->mg on day one and 10<!--> <!-->mg on day two) along with buprenorphine/naloxone. Primary outcomes included safety and tolerability: adverse events, physiologic measures, sedation level assessments. Generalized linear mixed model analysis assessed the effect of study drug and time on outcomes.</div></div><div><h3>Results</h3><div>N=18 (14=male, 4=female) were randomized to lemborexant (n=12) or placebo (n=6). No unanticipated problems occurred; five adverse events occurred in the lemborexant group and two in the placebo group with no serious adverse events. None of the physiologic measures showed a significant interaction of time and placebo vs. lemborexant (5 or 10<!--> <!-->mg): Pulse oximetry (F=0.6; p=0.84), End-tidal CO2 (F=0.5; p=0.91), Heart rate (F=0.6; p=0.82), Systolic blood pressure (F=0.7; p=0.73), Diastolic blood pressure (F=2.0; p=0.06). At 9<!--> <!-->hours after study drug administration, all participants returned to baseline sedation levels and were discharged.</div></div><div><h3>Conclusions</h3><div>Findings support the initial safety and tolerability of lemborexant as an adjunctive treatment for insomnia in humans receiving buprenorphine for OUD. Future longitudinal work is warranted with larger samples.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100304"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the reasons for quitting and/or reducing alcohol among those who have received alcohol use disorder treatment","authors":"Christiana Prestigiacomo,&nbsp;Lindsey Fisher-Fox,&nbsp;Melissa A. Cyders","doi":"10.1016/j.dadr.2024.100300","DOIUrl":"10.1016/j.dadr.2024.100300","url":null,"abstract":"<div><div>Research has primarily studied reasons for quitting and/or reducing alcohol use in non-treatment samples. This systematic review aimed to characterize the reasons for quitting and/or reducing alcohol use among those who have received treatment for AUD and examine how reasons endorsed differ across measurement methods used. Articles were identified through PsycINFO, Web of Science, PubMed, and CINAHL. Twenty-one articles met inclusion criteria. Thematic coding revealed 21 unique themes in reasons for quitting and/or reducing. Common reasons included physical health issues, misalignment with personal goals, family influence, and social factors—also noted in non-treatment populations. Unique themes like hitting rock bottom and avoiding disapproval were identified, potentially linked to treatment initiation or development. The measurement approach influenced the reasons reported, highlighting the need for standardized methods. Common reasons are fundamental and are not a result of treatment, while others are unique to individuals who have received AUD treatment, which may suggest that they are critical in leading one to seek treatment or may be developed during treatment. Assessing and tailoring treatment based on these reasons may enhance outcomes. Standardizing how we measure reasons for quitting or reducing alcohol is crucial for comparing studies and improving treatment. Future research should evaluate reasons over time, assess their importance at different treatment stages, and use varied assessment strategies for comprehensive insights.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"13 ","pages":"Article 100300"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142722042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discovering opioid slang on social media: A Word2Vec approach with reddit data","authors":"E. Holbrook,&nbsp;B. Wiskur,&nbsp;Z. Nagykaldi","doi":"10.1016/j.dadr.2024.100302","DOIUrl":"10.1016/j.dadr.2024.100302","url":null,"abstract":"<div><div>The CDC reported that the overdose of prescription or illicit opioids was responsible for the deaths of over 80,000 Americans in 2021. Social media is a valuable source of insight into problematic patterns of substance misuse. The way people converse with illicit drugs in online forums is highly variable, and slang terms are frequently used. Manually identifying names of specific drugs can be difficult in both time and labor.</div></div><div><h3>Subjects and methods</h3><div>The study utilized the Gensim Python library and its Word2Vec neural network model to develop an auto-encoding neural network, enabling the innovative analysis of drug-related discourse downloaded from the Reddit website. The slang terms were then used to qualitatively analyze the topics and categories of drugs discussed on the forum.</div></div><div><h3>Results</h3><div>The inclusion of slang terms facilitated the introduction of 200,000 specific mentions of opioid drugs and that stimulant drugs share a substantial semantic similarity with opioids, a 200 % increase in the number of drug-related terms as compared to using existing datasets.</div></div><div><h3>Conclusions</h3><div>This study advances the academic field with an extended collection of drug-related terms, offering a useful methodology and resource for tackling the opioid crisis with innovative, reduced-time detection and surveillance methods.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"13 ","pages":"Article 100302"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large decrease in syringe distribution following the introduction of fentanyl in King County, Washington","authors":"Sara N. Glick ,&nbsp;Joe Tinsley ,&nbsp;Laura Pritchard Wirkman ,&nbsp;Apoorva Mallya ,&nbsp;Peter Cleary ,&nbsp;Matthew R. Golden ,&nbsp;Thomas Fitzpatrick","doi":"10.1016/j.dadr.2024.100301","DOIUrl":"10.1016/j.dadr.2024.100301","url":null,"abstract":"<div><h3>Background</h3><div>Syringe services programs (SSPs) serve as key platforms to deliver harm reduction services to people who use drugs (PWUD). Changes in drug supply and drug consumption behaviors, particularly the increasing use of fentanyl through non-injection methods, may impact SSP utilization.</div></div><div><h3>Material and Methods</h3><div>We collected routine program data from three SSPs in King County, Washington. Trends in the annual number of syringes distributed and client encounters were assessed using joinpoint regression analysis to determine when statistically significant changes in trends in annual totals occurred and annual percent change (APC) during each period.</div></div><div><h3>Results</h3><div>The number of syringes distributed per year through King County SSPs reached a maximum of 8,733,413 in 2020 and then decreased sharply to 2,482,056 by 2023. Annual syringe distribution totals were stable or increasing during all periods from 1989 to 2020 (APC range: 2.0–35.3 %), and only developed a decreasing trend between 2020 and 2023 (APC=-32.8 %). Total number of SSP client encounters per year was stable between 2010 and 2023 (APC=0.7 %), but an increasing trend in encounters was identified starting in 2008 (APC=4.4 %) at a community-based SSP that distributed safer smoking supplies (pipes).</div></div><div><h3>Discussion</h3><div>A precipitous decline in syringe distribution through King County SSPs began in 2020 and continued through 2023, which coincided with increasing availability of fentanyl in the local drug market. Nevertheless, the trends in client encounters highlight that PWUD continued to seek harm reduction services, with preliminary evidence that distribution of safer smoking supplies may increase the number of client visits.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"13 ","pages":"Article 100301"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The power of lived experience in optimizing US policymakers’ engagement with substance use research: A series of rapid-cycle randomized controlled trials","authors":"Elizabeth C. Long ,&nbsp;Riley Loria ,&nbsp;Jessica Pugel ,&nbsp;Patrick O’Neill ,&nbsp;Camille C. Cioffi ,&nbsp;Charleen Hsuan ,&nbsp;Glenn Sterner ,&nbsp;D. Max Crowley ,&nbsp;J. Taylor Scott","doi":"10.1016/j.dadr.2024.100299","DOIUrl":"10.1016/j.dadr.2024.100299","url":null,"abstract":"<div><h3>Background</h3><div>Research can inform policies on substance use/substance use disorders (SU/SUDs), yet there is limited experimental investigation into strategies for optimizing policymakers’ engagement with SU/SUD research. This study tested the use of narratives to boost policymakers’ research engagement.</div></div><div><h3>Methods</h3><div>In five rapid-cycle randomized controlled trials, SU/SUD research fact sheets were emailed to US legislative policymakers. We tested the use of narratives on the number of email opens, fact sheet clicks, and replies, relative to control emails without narratives. Narratives described lived experience with SU/SUD or motivations to study SU/SUD. The sender was a person with lived experience who authored the narrative or an author of the fact sheet.</div></div><div><h3>Results</h3><div>When the narrative was about the sender’s <em>own</em> lived experience (Trial 1), or when the narrative was about the sender's motivations to study SU/SUDs (Trial 2), the fact sheet was clicked more than the control (<em>p</em>=.049; <em>p</em>=.012; respectively). When the narrative was about someone <em>else’s</em> experience (Trials 3 and 4), the email was opened (<em>p’s</em>&lt;.001) and replied to (<em>p’s</em>&lt;.001) less, and the fact sheet was clicked (<em>p’s</em>&lt;.001) less. Lastly, emails with lived experience narratives were replied to more than the control, regardless of sender (fact sheet author: <em>p</em>=.028; narrative author: <em>p</em>=.002; Trial 5), but were opened more if the sender authored the narrative (<em>p</em>&lt;.001).</div></div><div><h3>Conclusions</h3><div>Policymakers’ engagement with SU/SUD research generally increased when the sender was telling their own story. This work highlights the power of people with lived experience and informs strategies for optimizing policymakers’ engagement with SU/SUD research.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"13 ","pages":"Article 100299"},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between social norms and at-risk status for e-cigarette use: A sex-stratified analysis of Texas sixth-grade students","authors":"Sarina A. Attri ,&nbsp;Andrew E. Springer ,&nbsp;Baojiang Chen ,&nbsp;Steven H. Kelder ,&nbsp;Dale S. Mantey","doi":"10.1016/j.dadr.2024.100296","DOIUrl":"10.1016/j.dadr.2024.100296","url":null,"abstract":"<div><h3>Background</h3><div>E-cigarette use remains high among adolescents, underscoring the need to identify targetable risk factors for intervention. This study examines associations between two social norms constructs (prevalence misperceptions and social acceptability) and at-risk status for e-cigarette use among Texas early adolescents.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional analysis of baseline data from the CATCH My Breath study, which included n=1032 Texas sixth graders. Students who had ever used or were susceptible to using e-cigarettes were categorized as at-risk for long-term use. Susceptibility was measured using a 3-item index assessing curiosity, intentions, and receptivity to using e-cigarettes. Multi-level logistic regressions assessed associations between social norm constructs and at-risk status for the full and sex-stratified samples. Covariates were race, ethnicity, academics, household/peer tobacco use.</div></div><div><h3>Results</h3><div>Overall, 36 % of 6th grade students were at-risk for e-cigarette use. Approximately 49 % of students overestimated peer e-cigarette use (“prevalence misperceptions”), and 43 % believed adolescent e-cigarette use is highly acceptable (“social acceptability”). Controlling for covariates, students with medium (aOR=1.89; 95 %CI=1.35–2.65) and high (aOR=1.98; 95 %CI=1.41–2.78) prevalence misperceptions had greater odds of being at-risk for e-cigarette use than those with low misperceptions. Students reporting medium (aOR=2.50; 95 %CI=1.66–3.76) and high (aOR=4.70; 95 %CI=3.21–6.90) social acceptability had greater odds of being at-risk for e-cigarette use than those reporting low acceptability. This association was stronger for females, relative to males.</div></div><div><h3>Conclusions</h3><div>Greater prevalence misperceptions and social acceptability were associated with being at-risk for e-cigarette use among this sample of Texas early adolescents. Interventions should consider incorporating these social norms into intervention content.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"13 ","pages":"Article 100296"},"PeriodicalIF":0.0,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142652332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}