Discover nano最新文献_第7页

Integrated insulin-iron nanoparticles: a multi-modal approach for receptor-specific bioimaging, reactive oxygen species scavenging, and wound healing. 集成胰岛素-铁纳米粒子：用于受体特异性生物成像、活性氧清除和伤口愈合的多模式方法。

Discover nano Pub Date : 2024-05-30 DOI: 10.1186/s11671-024-04024-6

Komal Attri, Bhupendra Chudasama, Roop L Mahajan, Diptiman Choudhury

{"title":"Integrated insulin-iron nanoparticles: a multi-modal approach for receptor-specific bioimaging, reactive oxygen species scavenging, and wound healing.","authors":"Komal Attri, Bhupendra Chudasama, Roop L Mahajan, Diptiman Choudhury","doi":"10.1186/s11671-024-04024-6","DOIUrl":"10.1186/s11671-024-04024-6","url":null,"abstract":"Metallic nanoparticles have emerged as a promising option for various biological applications, owing to their distinct characteristics such as small size, optical properties, and ability to exhibit luminescence. In this study, we have successfully employed a one-pot method to synthesize multifunctional insulin-protected iron [Fe(II)] nanoparticles denoted as [IFe(II)NPs]. The formation of IFe(II)NPs is confirmed by the presence of FTIR bonds at 447.47 and 798.28 cm-1, corresponding to Fe-O and Fe-N bonds, respectively. Detailed analysis of the HR-TEM-EDS-SAED data reveals that the particles are spherical in shape, partially amorphous in nature, and have a diameter of 28.6 ± 5.2 nm. Additionally, Metal Ion Binding (MIB) and Protein Data Bank (PDB) analyses affirm the binding of iron ions to the insulin hexamer. Our findings underscore the potential of IFe(II)NPs as a promising new platform for a variety of biomedical applications due to their high signal-to-noise ratio, and minimal background fluorescence. The particles are highly luminescent, biocompatible, and have a significant quantum yield (0.632). Exemplar applications covered in this paper include insulin receptor recognition and protection against reactive oxygen species (ROS), harmful molecules known to inflict damage on cells and DNA. The IFe(II)NPs effectively mitigate ROS-induced inflammation, which is a hinderance to wound recovery, thereby facilitating enhanced wound recovery.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"96"},"PeriodicalIF":0.0,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11139842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing LED technology: the FDCSP element's breakthrough in mini and micro-LED packaging and backlight module enhancement. 推进 LED 技术：FDCSP 元件在迷你和微型 LED 封装和背光模块增强方面的突破。

Discover nano Pub Date : 2024-05-28 DOI: 10.1186/s11671-024-04033-5

Jo-Hsiang Chen, Che-Hsuan Huang, Tzu-Yi Lee, Fang-Chung Chen, Tsung-Sheng Kao, Hao-Chung Kuo

{"title":"Advancing LED technology: the FDCSP element's breakthrough in mini and micro-LED packaging and backlight module enhancement.","authors":"Jo-Hsiang Chen, Che-Hsuan Huang, Tzu-Yi Lee, Fang-Chung Chen, Tsung-Sheng Kao, Hao-Chung Kuo","doi":"10.1186/s11671-024-04033-5","DOIUrl":"10.1186/s11671-024-04033-5","url":null,"abstract":"In this research, we introduce an advanced methodology for the calculation of bulk light sources tailored for free-form surface design, focusing on the principle of energy conservation. This method is especially relevant for the evolving needs of micro-LED packaging, highlighting its potential in this burgeoning field. Our work includes the development of an algorithm for creating freeform-designed chip-scale package (FDCSP) components. These components seamlessly integrate LEDs and lenses, underscoring our commitment to advancing free-form surface design in chip-level packaging. By adhering to the principle of energy conservation, our approach facilitates a meticulous comparison of simulation outcomes with predefined target functions. This enables the iterative correction of discrepancies, employing layering techniques to refine the design until the simulated results closely align with our goals, as demonstrated by an appropriate difference curve. The practical application of these simulations leads to the innovative design of FDCSP devices. Notably, these devices are not just suitable for traditional applications in backlight modules but are explicitly optimized for the emerging sector of micro-LED packaging. Our successful demonstration of these FDCSP devices within backlight modules represents a significant achievement. It underscores the effectiveness of our design strategy and its expansive potential to transform micro-LED packaging solutions. This research not only contributes to the theoretical understanding of energy conservation in lighting design but also paves the way for groundbreaking applications in micro-LED and backlight module technologies.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"94"},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11133291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141163061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green synthesis of silver nanoparticle using pollen extract from Tetragonisca angustula a stingless bee. 利用无刺蜂 Tetragonisca angustula 的花粉提取物绿色合成银纳米粒子。

Discover nano Pub Date : 2024-05-27 DOI: 10.1186/s11671-024-04038-0

Ana Carolina Costa Santos, Gabriela Carvalho Batista, Rafaela Cavalcante Cerqueira, Mariana Gonçalves Lisboa, Joberth Lee Correa, Tamiris Sabrina Rodrigues, Murillo Néia Thomaz da Silva, Vinícius Prado Bittar, Serena Mares Malta, Natalia Carine Lima Dos Santos, Foued Salmen Espindola, Ana Maria Bonetti, Carlos Ueira-Vieira

{"title":"Green synthesis of silver nanoparticle using pollen extract from Tetragonisca angustula a stingless bee.","authors":"Ana Carolina Costa Santos, Gabriela Carvalho Batista, Rafaela Cavalcante Cerqueira, Mariana Gonçalves Lisboa, Joberth Lee Correa, Tamiris Sabrina Rodrigues, Murillo Néia Thomaz da Silva, Vinícius Prado Bittar, Serena Mares Malta, Natalia Carine Lima Dos Santos, Foued Salmen Espindola, Ana Maria Bonetti, Carlos Ueira-Vieira","doi":"10.1186/s11671-024-04038-0","DOIUrl":"10.1186/s11671-024-04038-0","url":null,"abstract":"This study explores the green synthesis of silver nanoparticles (AgNPs) using a methanolic extract of fermented pollen from Tetragonisca angustula, a species of stingless bees. The AgNPs exhibit spherical morphology, low charge values, and suspension stability, with their unique composition attributed to elements from the pollen extract. Antioxidant assays show comparable activity between the pollen extract and AgNPs, emphasizing the retention of antioxidant effects. The synthesized AgNPs demonstrate antimicrobial activity against multidrug-resistant bacteria, highlighting their potential in combating bacterial resistance. The AgNPs exhibit no toxic effects on Drosophila melanogaster and even enhance the hatching rate of eggs. The study underscores the innovative use of stingless bee pollen extract in green synthesis, offering insights into the varied applications of AgNPs in biomedicine.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"92"},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11130103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart integration of cold plasma stream and surface discharge with ns laser ablation for composite nanomaterial. 冷等离子体流和表面放电与 ns 激光烧蚀的智能集成，用于复合纳米材料。

Discover nano Pub Date : 2024-05-27 DOI: 10.1186/s11671-024-04034-4

Hafiz Muhammad Akhtar, Muhammad Latif, Mahtab Ahmad Khan, M Abdullah, Taj Muhammad Khan

{"title":"Smart integration of cold plasma stream and surface discharge with ns laser ablation for composite nanomaterial.","authors":"Hafiz Muhammad Akhtar, Muhammad Latif, Mahtab Ahmad Khan, M Abdullah, Taj Muhammad Khan","doi":"10.1186/s11671-024-04034-4","DOIUrl":"10.1186/s11671-024-04034-4","url":null,"abstract":"In this paper, smart integration of cold dielectric barrier discharge (DBD) plasma in various geometrical arrangements with laser ablation at atmospheric pressure for nanomaterial was described. A composite Co:ZnO target was ablated in an airflow by a nanosecond (ns) laser (wavelength: 1064 nm, pulse duration: 30 ns) using fluence of 5 J-cm-2 at a repetition rate of 10 Hz. The nanomaterial produced under vertical and oblique plasma streams, surface discharge and gas flow, were compared. Utilization surface discharge markedly improved the material adhesion by altering surface intrinsic behavior, inducing anticipated surface energy activation, chemical changes, and the formation of a densely packed solid structure. Under all conditions, the material consistently retained its crystalline nature, elemental composition, and ultraviolet emission characteristics. These preliminary findings hold promise for additional research, suggesting avenues for making complex materials in a flexible environment. Such new advancements could facilitate applications in the biomedical, catalysis, pharmaceutical, and surgical device domains.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"93"},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11130095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiscale modelling of transport in polymer-based reverse-osmosis/nanofiltration membranes: present and future. 基于聚合物的反渗透/纳滤膜的多尺度传输建模：现状与未来。

Discover nano Pub Date : 2024-05-21 DOI: 10.1186/s11671-024-04020-w

Haochen Zhu, Anthony Szymczyk, Aziz Ghoufi

{"title":"Multiscale modelling of transport in polymer-based reverse-osmosis/nanofiltration membranes: present and future.","authors":"Haochen Zhu, Anthony Szymczyk, Aziz Ghoufi","doi":"10.1186/s11671-024-04020-w","DOIUrl":"10.1186/s11671-024-04020-w","url":null,"abstract":"Nanofiltration (NF) and reverse osmosis (RO) processes are physical separation technologies used to remove contaminants from liquid streams by employing dense polymer-based membranes with nanometric voids that confine fluids at the nanoscale. At this level, physical properties such as solvent and solute permeabilities are intricately linked to molecular interactions. Initially, numerous studies focused on developing macroscopic transport models to gain insights into separation properties at the nanometer scale. However, continuum-based models have limitations in nanoconfined situations that can be overcome by force field molecular simulations. Continuum-based models heavily rely on bulk properties, often neglecting critical factors like liquid structuring, pore geometry, and molecular/chemical specifics. Molecular/mesoscale simulations, while encompassing these details, often face limitations in time and spatial scales. Therefore, achieving a comprehensive understanding of transport requires a synergistic integration of both approaches through a multiscale approach that effectively combines and merges both scales. This review aims to provide a comprehensive overview of the state-of-the-art in multiscale modeling of transport through NF/RO membranes, spanning from the nanoscale to continuum media.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"91"},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of nonlinear bending behavior of nano-switches considering surface effects. 考虑表面效应的纳米开关非线性弯曲行为分析

Discover nano Pub Date : 2024-05-20 DOI: 10.1186/s11671-024-04030-8

Fan Yang, Xuyang Wang, Xianlai Song, Weilin Yang

{"title":"Analysis of nonlinear bending behavior of nano-switches considering surface effects.","authors":"Fan Yang, Xuyang Wang, Xianlai Song, Weilin Yang","doi":"10.1186/s11671-024-04030-8","DOIUrl":"10.1186/s11671-024-04030-8","url":null,"abstract":"Nano-switch structures are important control elements in nanoelectromechanical systems and have potential applications in future nanodevices. This paper analyzes the effects of surface effects, geometric nonlinearity, electrostatic forces, and intermolecular forces on the nonlinear bending behavior and adhesion stability of nano-switches. Based on the Von Karman geometric nonlinearity theory, four types of boundary conditions for the nano-switch structure were specifically calculated. The results show that surface effects have a significant impact on the nonlinear bending and adhesion stability of nano-switches. Surface effects increase the adhesion voltage of the nano-switch and decrease its adhesion displacement, and as the size of the nano-switch structure increases, the impact of surface effects decreases. A comparative analysis of the linear theory and the nonlinear theory results shows that the adhesion voltage predicted by the linear theory is smaller than that predicted by the nonlinear theory. The effect of geometric nonlinearity increases as the size of the nano-switch structure increases, as the distance between the electrodes increases, and as the aspect ratio of the nano-switch structure increases. These findings provide theoretical support and reference for the design and use of future nanodevices and nanoelectromechanical systems.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"90"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile synthesis of hierarchical W₁₈O₄₉ microspheres by solvothermal method and their optical absorption properties. 溶热法简便合成分层 W18O49 微球及其光吸收特性。

Discover nano Pub Date : 2024-05-17 DOI: 10.1186/s11671-024-03990-1

Yuanpeng Xiong, Bo Wu, Yuanzhi Lin, Mingwen Zhang, Jintian Chen

引用次数: 0

Research on high sensitivity piezoresistive sensor based on structural design. 基于结构设计的高灵敏度压阻传感器研究。

Discover nano Pub Date : 2024-05-16 DOI: 10.1186/s11671-024-03971-4

Wei Li, Xing Liu, Yifan Wang, Lu Peng, Xin Jin, Zhaohui Jiang, Zengge Guo, Jie Chen, Wenyu Wang

引用次数: 0

Eco-friendly bio-nanocomposites: pioneering sustainable biomedical advancements in engineering. 生态友好型生物纳米复合材料：开创可持续生物医学工程的先河。

Discover nano Pub Date : 2024-05-09 DOI: 10.1186/s11671-024-04007-7

J Nandhini, E Karthikeyan, S Rajeshkumar

{"title":"Eco-friendly bio-nanocomposites: pioneering sustainable biomedical advancements in engineering.","authors":"J Nandhini, E Karthikeyan, S Rajeshkumar","doi":"10.1186/s11671-024-04007-7","DOIUrl":"10.1186/s11671-024-04007-7","url":null,"abstract":"Biomedical nanocomposites, which are an upcoming breed of mischievous materials, have ushered in a new dimension in the healthcare sector. Incorporating these materials tends to boost features this component already possesses and give might to things these components could not withstand alone. The biopolymer, which carries the nanoparticles, can simultaneously improve the composite's stiffness and biological characteristics, and vice versa. This increases the options of the composite and the number of times it can be used. The bio-nanocomposites and nanoparticles enable the ecocompatibility of the medicine in their biodegradability, and they, in this way, have ecological sustainability. The outcome is the improved properties of medicine and its associated positive impact on the environment. They have broad applications in antimicrobial agents, drug carriers, tissue regeneration, wound care, dentistry, bioimaging, and bone filler, among others. The dissertation on the elements of bio-nanocomposites emphasizes production techniques, their diverse applications in medicine, match-up issues, and future-boasting prospects in the bio-nanocomposites field. Through the utilization of such materials, scientists can develop more suitable for the environment and healthy biomedical solutions, and world healthcare in this way improves as well.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"86"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11082105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of temporal resolution in single particle tracking analysis. 单粒子跟踪分析中时间分辨率的影响

Discover nano Pub Date : 2024-05-09 DOI: 10.1186/s11671-024-04029-1

Chiara Schirripa Spagnolo, Stefano Luin

{"title":"Impact of temporal resolution in single particle tracking analysis.","authors":"Chiara Schirripa Spagnolo, Stefano Luin","doi":"10.1186/s11671-024-04029-1","DOIUrl":"10.1186/s11671-024-04029-1","url":null,"abstract":"Temporal resolution is a key parameter in the observation of dynamic processes, as in the case of single molecules motions visualized in real time in two-dimensions by wide field (fluorescence) microscopy, but a systematic investigation of its effects in all the single particle tracking analysis steps is still lacking. Here we present tools to quantify its impact on the estimation of diffusivity and of its distribution using one of the most popular tracking software for biological applications on simulated data and movies. We found important shifts and different widths for diffusivity distributions, depending on the interplay of temporal sampling conditions with various parameters, such as simulated diffusivity, density of spots, signal-to-noise ratio, lengths of trajectories, and kind of boundaries in the simulation. We examined conditions starting from the ones of experiments on the fluorescently labelled receptor p75NTR, a relatively fast-diffusing membrane receptor (diffusivity around 0.5-1 µm2/s), visualized by TIRF microscopy on the basal membrane of living cells. From the analysis of the simulations, we identified the best conditions in cases similar to these ones; considering also the experiments, we could confirm a range of values of temporal resolution suitable for obtaining reliable diffusivity results. The procedure we present can be exploited in different single particle/molecule tracking applications to find an optimal temporal resolution.","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"87"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11082114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0