Discover mental health最新文献

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Key actors in behavioral health services availability and accessibility research: a scoping review bibliometric analysis. 行为健康服务可用性和可及性研究的主要参与者:范围审查文献计量分析。
Discover mental health Pub Date : 2024-05-03 DOI: 10.1007/s44192-024-00068-3
Cole Hooley, Danielle R Adams, Wai Yan Ng, Carrie L E Wendt, Cory B Dennis
{"title":"Key actors in behavioral health services availability and accessibility research: a scoping review bibliometric analysis.","authors":"Cole Hooley, Danielle R Adams, Wai Yan Ng, Carrie L E Wendt, Cory B Dennis","doi":"10.1007/s44192-024-00068-3","DOIUrl":"https://doi.org/10.1007/s44192-024-00068-3","url":null,"abstract":"<p><p>This bibliometric review aims to identify key actors in the behavioral health services availability/accessibility literature. Coalescing information about these actors could support subsequent research efforts to improve the availability and accessibility of behavioral health services. The authors used a scoping review method and a bibliometric approach. The articles came from Medline, Embase, Web of Science, CINAHL, and PsycINFO. Articles were included if they assessed behavioral health service availability or accessibility quantitatively and were written in English. The final sample included 265 articles. Bibliometric data were extracted, coded, and verified. The authors analyzed the data using univariate and social network analyses. Publishing in this area has become more consistent and has grown since 2002. Psychiatric Services and Graduate Theses were the most frequently used publication venues. The National Institute on Drug Abuse, National Institute of Mental Health, and the Veterans Administration funded the most research. The most frequently used keyword was \"health services accessibility.\" The findings suggest that this literature is growing. There are a few clusters of researchers in this area. Government organizations primarily fund this research. The paper and supplementary materials list the top researchers, publication venues, funding sources, and key terms to promote further behavioral health availability/accessibility research.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11068714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does categorizing scale scores with cutoff points affect hypothesis-testing results? 用临界点对量表分数进行分类是否会影响假设检验结果?
Discover mental health Pub Date : 2024-04-22 DOI: 10.1007/s44192-024-00067-4
U. Sayılı, Esin Siddikoglu, Deniz Turgut, Hamza Emre Arisli, Betul Ceyhan, M. G. Gunver, Sevda Ozel Yildiz, E. Yurtseven, E. Erginoz
{"title":"Does categorizing scale scores with cutoff points affect hypothesis-testing results?","authors":"U. Sayılı, Esin Siddikoglu, Deniz Turgut, Hamza Emre Arisli, Betul Ceyhan, M. G. Gunver, Sevda Ozel Yildiz, E. Yurtseven, E. Erginoz","doi":"10.1007/s44192-024-00067-4","DOIUrl":"https://doi.org/10.1007/s44192-024-00067-4","url":null,"abstract":"","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140673336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between subjective difficulty in interoceptive processing and accuracy of heartbeat perception in autistic individuals 自闭症患者互感处理的主观困难与心跳感知准确性之间的关系
Discover mental health Pub Date : 2024-04-18 DOI: 10.1007/s44192-024-00065-6
C. Itoi, Yuta Ujiie, Yuuki Ooishi, M. Kashino
{"title":"The relationship between subjective difficulty in interoceptive processing and accuracy of heartbeat perception in autistic individuals","authors":"C. Itoi, Yuta Ujiie, Yuuki Ooishi, M. Kashino","doi":"10.1007/s44192-024-00065-6","DOIUrl":"https://doi.org/10.1007/s44192-024-00065-6","url":null,"abstract":"","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140689927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebrospinal fluid metabolomes of treatment-resistant depression subtypes and ketamine response: a pilot study 耐药抑郁症亚型的脑脊液代谢组与氯胺酮反应:一项试点研究
Discover mental health Pub Date : 2024-04-17 DOI: 10.1007/s44192-024-00066-5
Jon Berner, Animesh Acharjee
{"title":"Cerebrospinal fluid metabolomes of treatment-resistant depression subtypes and ketamine response: a pilot study","authors":"Jon Berner, Animesh Acharjee","doi":"10.1007/s44192-024-00066-5","DOIUrl":"https://doi.org/10.1007/s44192-024-00066-5","url":null,"abstract":"","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140690818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A network of transcriptomic signatures identifies novel comorbidity mechanisms between schizophrenia and somatic disorders. 转录组特征网络确定了精神分裂症与躯体疾病之间的新型合并机制。
Discover mental health Pub Date : 2024-04-04 DOI: 10.1007/s44192-024-00063-8
Youcheng Zhang, Vinay S Bharadhwaj, Alpha T Kodamullil, Carl Herrmann
{"title":"A network of transcriptomic signatures identifies novel comorbidity mechanisms between schizophrenia and somatic disorders.","authors":"Youcheng Zhang, Vinay S Bharadhwaj, Alpha T Kodamullil, Carl Herrmann","doi":"10.1007/s44192-024-00063-8","DOIUrl":"https://doi.org/10.1007/s44192-024-00063-8","url":null,"abstract":"<p><p>The clinical burden of mental illness, in particular schizophrenia and bipolar disorder, are driven by frequent chronic courses and increased mortality, as well as the risk for comorbid conditions such as cardiovascular disease and type 2 diabetes. Evidence suggests an overlap of molecular pathways between psychotic disorders and somatic comorbidities. In this study, we developed a computational framework to perform comorbidity modeling via an improved integrative unsupervised machine learning approach based on multi-rank non-negative matrix factorization (mrNMF). Using this procedure, we extracted molecular signatures potentially explaining shared comorbidity mechanisms. For this, 27 case-control microarray transcriptomic datasets across multiple tissues were collected, covering three main categories of conditions including psychotic disorders, cardiovascular diseases and type II diabetes. We addressed the limitation of normal NMF for parameter selection by introducing multi-rank ensembled NMF to identify signatures under various hierarchical levels simultaneously. Analysis of comorbidity signature pairs was performed to identify several potential mechanisms involving activation of inflammatory response auxiliarily interconnecting angiogenesis, oxidative response and GABAergic neuro-action. Overall, we proposed a general cross-cohorts computing workflow for investigating the comorbid pattern across multiple symptoms, applied it to the real-data comorbidity study on schizophrenia, and further discussed the potential for future application of the approach.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10994898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospitalization and help-seeking among first episode psychosis patients 首次发病的精神病患者的住院和求助情况
Discover mental health Pub Date : 2024-04-03 DOI: 10.1007/s44192-024-00064-7
Anna Yee, Sarah Greene, Ashley Weiss, Serena Chaudhry, Spencer Steadman
{"title":"Hospitalization and help-seeking among first episode psychosis patients","authors":"Anna Yee, Sarah Greene, Ashley Weiss, Serena Chaudhry, Spencer Steadman","doi":"10.1007/s44192-024-00064-7","DOIUrl":"https://doi.org/10.1007/s44192-024-00064-7","url":null,"abstract":"","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140748997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opportunities and challenges for the use of deep brain stimulation in the treatment of refractory major depression. 使用脑深部刺激治疗难治性重度抑郁症的机遇与挑战。
Discover mental health Pub Date : 2024-03-14 DOI: 10.1007/s44192-024-00062-9
Prashin Unadkat, Joao Quevedo, Jair Soares, Albert Fenoy
{"title":"Opportunities and challenges for the use of deep brain stimulation in the treatment of refractory major depression.","authors":"Prashin Unadkat, Joao Quevedo, Jair Soares, Albert Fenoy","doi":"10.1007/s44192-024-00062-9","DOIUrl":"10.1007/s44192-024-00062-9","url":null,"abstract":"<p><p>Major Depressive Disorder continues to remain one of the most prevalent psychiatric diseases globally. Despite multiple trials of conventional therapies, a subset of patients fail to have adequate benefit to treatment. Deep brain stimulation (DBS) is a promising treatment in this difficult to treat population and has shown strong antidepressant effects across multiple cohorts. Nearly two decades of work have provided insights into the potential for chronic focal stimulation in precise brain targets to modulate pathological brain circuits that are implicated in the pathogenesis of depression. In this paper we review the rationale that prompted the selection of various brain targets for DBS, their subsequent clinical outcomes and common adverse events reported. We additionally discuss some of the pitfalls and challenges that have prevented more widespread adoption of this technology as well as future directions that have shown promise in improving therapeutic efficacy of DBS in the treatment of depression.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10940557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140133370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steroid-induced mania in a patient with previously well-controlled organic bipolar 1-like affective disorder secondary to acquired brain injury: case report and literature review. 一名因后天性脑损伤继发的双相1型情感障碍患者由类固醇诱发的躁狂症:病例报告和文献综述。
Discover mental health Pub Date : 2024-03-08 DOI: 10.1007/s44192-024-00061-w
Jacob D King, Thomas Elliott, Alexandra Pitman
{"title":"Steroid-induced mania in a patient with previously well-controlled organic bipolar 1-like affective disorder secondary to acquired brain injury: case report and literature review.","authors":"Jacob D King, Thomas Elliott, Alexandra Pitman","doi":"10.1007/s44192-024-00061-w","DOIUrl":"10.1007/s44192-024-00061-w","url":null,"abstract":"<p><p>Steroid-induced neuropsychiatric sequelae are common, and pose significant risks to people usually receiving glucocorticoids in the context of physical illness. Steroid-induced mania and hypomania are the most common of the acute complications, yet despite great progress in understandings in neurophysiology there are no recent studies which review the factors which might predict who will experience this severe complication, nor are there consensus guidelines on management. We report the unusual case of a woman in her 50s admitted to a psychiatric unit with steroid-induced mania despite compliance with two mood stabilisers, several days after the administration of a Dexamethasone and Docetaxel chemotherapy regime adjunctive to lumpectomy for breast cancer. She had previously been diagnosed with an organic affective disorder (with classical bipolar 1 pattern) following severe ventriculitis related to ventricular drain insertion for obstructive hydrocephalus secondary to a colloid cyst. She had no psychiatric illness before this brain injury, but has a maternal history of idiopathic bipolar 1 affective disorder. Her episode of steroid-induced mania resolved following use of sedative medications, continuation of her existing mood stabilisers, and reductions of the steroid dosing in collaboration with her oncology team, which also protected her from further manic relapses during continued chemotherapy. Established mental illness, a family history, and acquired brain injury may reflect risk factors for steroid-induced mania through currently unclear pathways. Future epidemiological studies could better confirm these observations, and basic neuroscience may look to further explore the role of extrinsic glucocorticoids in the pathophysiology of affective disorders.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the executive functions and quality of life in a sample of Egyptian male adolescents with substance use disorder: A case-control study. 评估埃及男性青少年药物使用障碍患者的执行功能和生活质量:病例对照研究。
Discover mental health Pub Date : 2024-03-04 DOI: 10.1007/s44192-024-00060-x
Hassan Mohammed Sonbol, Youmna Sabri, Mohamed Shahda, Eman Abdallah Shouman
{"title":"Evaluation of the executive functions and quality of life in a sample of Egyptian male adolescents with substance use disorder: A case-control study.","authors":"Hassan Mohammed Sonbol, Youmna Sabri, Mohamed Shahda, Eman Abdallah Shouman","doi":"10.1007/s44192-024-00060-x","DOIUrl":"10.1007/s44192-024-00060-x","url":null,"abstract":"<p><strong>Background: </strong>Adolescent substance use is a major problem that has serious medical, psychological, and legal consequences later in life. Substance use disorder is closely linked to deficits in executive functions. Impaired executive functions (EFs) have been linked to all stages of the substance use disorder (SUD) life cycle, increasing the likelihood of commencing use, escalating use more quickly, and increasing the likelihood of relapsing following treatment. The current study aimed at evaluating of the executive functions and quality of life in a sample of adolescent Egyptian males with substance use disorder.</p><p><strong>Results: </strong>A significantly higher mean Trail Making Test-A, B (TMT-A and TMT-B) scores among studied cases than the control group (equals lower executive functions) with a mean score of TMT-A is 74.38 versus 63.2 among controls and for TMT-B; the mean score for control is 97.22 versus 142.04 among cases. A statistically significant difference between the case and control groups on all quality of life scores measuring the following domains: general health and well-being, physical health, psychological health, social interactions, and the environment, also there has been a negative correlation between TMT-A and the environmental domain (r = - 0.279) and TMT-B with the same variable (r = - 0.414).</p><p><strong>Conclusions: </strong>Substance use disorders are a major health problem among youth. Deficits in executive functions are strongly associated with adolescent substance use. The more affected executive functions are associated with more affected quality of life of these patients.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10912384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new performance-based measure of personality functioning impairment: development and preliminary evaluation of reliability and validity. 基于表现的人格功能障碍新测量方法:开发及信度和效度初步评估。
Discover mental health Pub Date : 2024-02-22 DOI: 10.1007/s44192-024-00059-4
Adam P Natoli, Chloe M Rodriguez
{"title":"A new performance-based measure of personality functioning impairment: development and preliminary evaluation of reliability and validity.","authors":"Adam P Natoli, Chloe M Rodriguez","doi":"10.1007/s44192-024-00059-4","DOIUrl":"10.1007/s44192-024-00059-4","url":null,"abstract":"<p><p>Personality functioning impairment is at the center of many dimensional models of personality. Available measures of personality functioning impairment are limited to self-report, clinician-/informant-rated, and interview methods. Although researchers have begun investigating established performance-based instruments' potential for assessing personality functioning impairment, administration and scoring of these instruments is complex and the latent variables they measure diverge from personality functioning impairment as described in the ICD-11 and the Alternative Model for Personality Disorders (AMPD) of the DSM. We address this absence by developing and psychometrically evaluating the Level of Personality Functioning Scale-Questionnaire-based Implicit Association Test (LPFS-qIAT). The LPFS-qIAT's psychometric properties were evaluated across four studies, producing initial evidence supporting the new instrument's reliability as well as its convergent, discriminant, and criterion-related validity. As the first performance-based measure of personality functioning impairment that aligns with the AMPD and, to a degree the ICD-11, that is easily administered, scored, and interpreted, the LPFS-qIAT shows potential to become a valuable tool in both research and clinical practice.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10884381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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