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[TES-GPS and VIRON: clinical trials on electrical stimulation for glaucomatous optic neuropathy]. [TES-GPS和VIRON：电刺激治疗青光眼视神经病变的临床试验]。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-27 DOI: 10.1007/s00347-026-02441-9
Katrin Lorenz, Anna Beck, Verena Prokosch, Andrea Antal, Johanna Pohlner, Michael Schittkowski
{"title":"[TES-GPS and VIRON: clinical trials on electrical stimulation for glaucomatous optic neuropathy].","authors":"Katrin Lorenz, Anna Beck, Verena Prokosch, Andrea Antal, Johanna Pohlner, Michael Schittkowski","doi":"10.1007/s00347-026-02441-9","DOIUrl":"https://doi.org/10.1007/s00347-026-02441-9","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recommend smoking cessation to prevent vision loss]. [建议戒烟预防视力下降]。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-24 DOI: 10.1007/s00347-026-02440-w
Robert P Finger, Alexander K Schuster
{"title":"[Recommend smoking cessation to prevent vision loss].","authors":"Robert P Finger, Alexander K Schuster","doi":"10.1007/s00347-026-02440-w","DOIUrl":"https://doi.org/10.1007/s00347-026-02440-w","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of central serous chorioretinopathy in comparison-microsecond-pulse laser versus photodynamic therapy. 微秒脉冲激光与光动力治疗中枢性浆液性脉络膜视网膜病变的比较。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-22 DOI: 10.1007/s00347-026-02433-9
Vasilena Sitnilska, Ulrike Brocks, Jan Tode, Georg Spital, Lebriz Altay
{"title":"Treatment of central serous chorioretinopathy in comparison-microsecond-pulse laser versus photodynamic therapy.","authors":"Vasilena Sitnilska, Ulrike Brocks, Jan Tode, Georg Spital, Lebriz Altay","doi":"10.1007/s00347-026-02433-9","DOIUrl":"https://doi.org/10.1007/s00347-026-02433-9","url":null,"abstract":"<p><p>The therapeutic management of central serous chorioretinopathy (CSC) remains challenging. Although CSC shows a high rate of self-resorption, frequent recurrences or chronification of the disease can result in irreversible loss of vision. Low-dose photodynamic therapy (half-dose or half-fluence PDT) represents the current standard of care for CSC, although regenerative laser procedures may also offer a safe and effective alternative for the treatment of CSC.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recurrent spontaneous hyphema assosiated with focal iris vascular leakage-successful treatment with argon laser photocoagulation]. 【复发性自发性前房积血伴局灶性虹膜血管渗漏——氩激光光凝治疗成功】。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-21 DOI: 10.1007/s00347-026-02438-4
Karla Knop, Tobias Röck, Karl Ulrich Bartz-Schmidt, Daniel Röck
{"title":"[Recurrent spontaneous hyphema assosiated with focal iris vascular leakage-successful treatment with argon laser photocoagulation].","authors":"Karla Knop, Tobias Röck, Karl Ulrich Bartz-Schmidt, Daniel Röck","doi":"10.1007/s00347-026-02438-4","DOIUrl":"https://doi.org/10.1007/s00347-026-02438-4","url":null,"abstract":"<p><p>Spontaneous non-traumatic anterior chamber bleeding is rare and may be caused by focal vascular iris changes at the pupillary margin. A 53-year-old woman presented in 01/2024 with painless sudden visual loss in the left eye. Findings: a localized reddish vascular lesion at the 2 o'clock pupillary margin, no hyphema, no inflammation, and intraocular pressure of 15 mm Hg. In 02/2025, recurrence occurred with erythrocytes in the anterior chamber, renewed bleeding from the localized reddish vascular lesion at the pupillary margin, and IOP rise to 24 mm Hg. Iris fluorescein angiography showed localized hyperfluorescence with leakage. After initial pressure-lowering therapy, targeted argon laser photocoagulation was performed. This led to rapid stabilization without further bleeding or pressure elevation. The findings remained stable through 11/2025. The case highlights the diagnostic value of iris fluorescein angiography and the effectiveness of focal argon laser photocoagulation.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Valsalva retinopathy]. (并发视网膜病变)。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-20 DOI: 10.1007/s00347-026-02435-7
Clemens Niklas Rudolph, Peter Szurman, Colya N Englisch, Philip Wakili
{"title":"[Valsalva retinopathy].","authors":"Clemens Niklas Rudolph, Peter Szurman, Colya N Englisch, Philip Wakili","doi":"10.1007/s00347-026-02435-7","DOIUrl":"https://doi.org/10.1007/s00347-026-02435-7","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition and dietary supplements in age-related macular degeneration. 年龄相关性黄斑变性的营养和膳食补充剂。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-15 DOI: 10.1007/s00347-026-02432-w
Matthias M Mauschitz, Lukas Goerdt, Horst Helbig, Frank G Holz, Robert P Finger, Caroline Brandl
{"title":"Nutrition and dietary supplements in age-related macular degeneration.","authors":"Matthias M Mauschitz, Lukas Goerdt, Horst Helbig, Frank G Holz, Robert P Finger, Caroline Brandl","doi":"10.1007/s00347-026-02432-w","DOIUrl":"https://doi.org/10.1007/s00347-026-02432-w","url":null,"abstract":"<p><strong>Background: </strong>Nutrition has an influence on the condition of our retina and appears to play a role in the complex, multifactorial pathogenesis of age-related macular degeneration (AMD).</p><p><strong>Objectives: </strong>This article summarizes the current epidemiological evidence on nutrition and AMD and discusses the intake of specific nutrients as well as nutritional supplements and their potential role in prevention and disease modification.</p><p><strong>Material and methods: </strong>A narrative literature review of epidemiological studies, clinical trials and experimental work on the role of individual micronutrients, supplements and dietary patterns in AMD was carried out.</p><p><strong>Results: </strong>There is evidence of a protective effect for individual nutrients such as lutein, zeaxanthin, zinc and omega‑3 fatty acids. The AREDS studies in particular show a reduction in the progression of intermediate AMD to late stages through defined supplements. In addition, a Mediterranean diet correlates with a reduced risk of AMD. Nevertheless, the study results remain contradictory in some cases, which is due to methodological limitations and the complex pathogenesis of AMD.</p><p><strong>Discussion: </strong>Nutrition can potentially influence and reduce the risk for and progression of AMD. The existing literature underlines the potential of nutrition-based approaches, which must be further investigated in the future.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging pathogens of ocular infections due to environmental changes-what lies ahead? 环境变化引起的眼部感染新出现的病原体——未来会发生什么？
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-14 DOI: 10.1007/s00347-026-02434-8
M Roth, G Geerling, P Strzalkowski, H H Lindhof, R Guthoff
{"title":"Emerging pathogens of ocular infections due to environmental changes-what lies ahead?","authors":"M Roth, G Geerling, P Strzalkowski, H H Lindhof, R Guthoff","doi":"10.1007/s00347-026-02434-8","DOIUrl":"https://doi.org/10.1007/s00347-026-02434-8","url":null,"abstract":"<p><p>Due to the global effects of climate change numerous infectious diseases are increasingly spreading to regions that were previously hardly or only slightly affected. As ocular involvement is possible in many of these infectious diseases, we must also adapt to new pathogens and clinical pictures in Germany in the medium to long term. Using selected bacterial, viral and mycotic pathogens and diseases as examples, the causes of the increase in dissemination and the consequences for ophthalmology are presented.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for age-related macular degeneration. 年龄相关性黄斑变性的危险因素。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-14 DOI: 10.1007/s00347-026-02431-x
Caroline Brandl, Iris M Heid, H Helbig, Frank G Holz, Robert P Finger, Matthias M Mauschitz
{"title":"Risk factors for age-related macular degeneration.","authors":"Caroline Brandl, Iris M Heid, H Helbig, Frank G Holz, Robert P Finger, Matthias M Mauschitz","doi":"10.1007/s00347-026-02431-x","DOIUrl":"https://doi.org/10.1007/s00347-026-02431-x","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Salzmann-like corneal deposits-A case series]. [salzmann样角膜沉积-病例系列]。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-13 DOI: 10.1007/s00347-026-02430-y
Viola Merk, Berthold Seitz, Elias Flockerzi, Loay Daas, Tim Berger
{"title":"[Salzmann-like corneal deposits-A case series].","authors":"Viola Merk, Berthold Seitz, Elias Flockerzi, Loay Daas, Tim Berger","doi":"10.1007/s00347-026-02430-y","DOIUrl":"https://doi.org/10.1007/s00347-026-02430-y","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Real-life data of the IVI interval after switching to faricimab therapy]. [转入法利昔单抗治疗后IVI间隔的真实数据]。
IF 0.6
Die Ophthalmologie Pub Date : 2026-04-01 Epub Date: 2026-02-06 DOI: 10.1007/s00347-026-02389-w
D S Muranyi, J Molling, U Hammer, A Habermann, G Lehmann, E Luci, C Buchwald, T Hammer
{"title":"[Real-life data of the IVI interval after switching to faricimab therapy].","authors":"D S Muranyi, J Molling, U Hammer, A Habermann, G Lehmann, E Luci, C Buchwald, T Hammer","doi":"10.1007/s00347-026-02389-w","DOIUrl":"10.1007/s00347-026-02389-w","url":null,"abstract":"<p><strong>Background: </strong>For neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME), intravitreal injection (IVI) of anti-vascular endothelial growth factor (anti-VEGF) agents currently represents the standard of care. Both treatment intervals and the choice of the optimal agent are critical determinants of therapeutic outcomes.</p><p><strong>Objective: </strong>This study evaluated the effect of switching from established anti-VEGF agents (ranibizumab, bevacizumab or aflibercept) to faricimab on injection intervals in patients with nAMD or DME.</p><p><strong>Material and methods: </strong>Data were collected in a routine outpatient ophthalmology practice. Inclusion criteria were: (I) treatment according to a treat-and-extend protocol, (II) at least six intravitreal injections prior to switching to faricimab and (III) at least three subsequent faricimab injections. To assess disease-specific effects, patients were stratified into nAMD and DME subgroups.</p><p><strong>Results: </strong>A total of 86 patients with a mean of 37 prior injections were included. The mean injection interval before switching to faricimab was 44 days. In the nAMD subgroup (n = 74, mean age 72 years), the interval significantly increased from 46 to 53 days (mean difference 7.45 days, p < 0.05). In the DME subgroup (n = 12, mean age 65 years), the interval significantly increased from 42 to 57 days (mean difference 15.25 days, p < 0.05). The effect size was moderate (Cohen's d = 0.56) with high statistical power (99.93%).</p><p><strong>Conclusion: </strong>Switching to faricimab resulted in a significant extension of treatment intervals in both indications, with patients with DME deriving the greatest benefit. Limitations include the small sample size and potential selection bias. These findings suggest an improved benefit-risk profile through reduced injection frequency. Additional real-world data and meta-analyses may help identify biomarkers to further individualize anti-VEGF therapy in the future.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"298-303"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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