Die Ophthalmologie最新文献_第10页

[Bilateral conspicuous iris configuration and elevation of intraocular pressure of unclear origin]. [双侧虹膜形态明显，眼压升高原因不明]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-01-13 DOI: 10.1007/s00347-024-02178-3

Lukas Schloesser, Robert P Finger, Somar Hasan

引用次数: 0

[Etiology of pediatric ocular trauma in a tertiary referral hospital in Tanzania]. [坦桑尼亚一家三级转诊医院的儿童眼外伤病因学]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-02-28 DOI: 10.1007/s00347-025-02194-x

Patrizia Krauss, Heiko Philippin, Karin M Knoll, Matthias Eidel, Martin M Nentwich, Peter Shah, Freda Sii, Evarista Mgaya, Furahini G Mndeme, Christopher Mwanansao

{"title":"[Etiology of pediatric ocular trauma in a tertiary referral hospital in Tanzania].","authors":"Patrizia Krauss, Heiko Philippin, Karin M Knoll, Matthias Eidel, Martin M Nentwich, Peter Shah, Freda Sii, Evarista Mgaya, Furahini G Mndeme, Christopher Mwanansao","doi":"10.1007/s00347-025-02194-x","DOIUrl":"10.1007/s00347-025-02194-x","url":null,"abstract":"Background: Ocular trauma in childhood is a major cause of unilateral acquired blindness in Africa [3]. The aim of the study was to identify the underlying mechanisms of injury in order to develop region-specific prevention strategies.Patients and methods: The study was performed at the Department of Ophthalmology of Bugando Medical Centre in Mwanza, Tanzania, during a 3-month observation period in spring 2019. All children under the age of 17 years who presented with acute eye injury or a history of ocular trauma within 4 years prior to presentation were included. The data collection was performed using a standardized questionnaire based on the UK Paediatric Ocular Trauma Study I, which was adapted to the specific local conditions.Results: We included 49 patients. The mean age at the time of injury was 7 years. Boys were affected more often than girls (69% vs. 31%). The most frequent objects causing injury were wooden sticks (45%). The majority of the injuries happened at home (51%). Only 35% of the patients presented at an eye unit within 24 h after the injury, while 26% waited longer than 7 days. The most common clinical finding was corneal laceration (73%) and 33 patients needed immediate surgical treatment.Conclusion: Ocular trauma in children is a frequent and important ophthalmological issue in Tanzania. To prevent these injuries, more public education concerning adult supervision and eye protection is needed. Furthermore, it is important to raise awareness about the need for an immediate presentation at an eye unit, which can help to achieve a better visual outcome.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"297-303"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Biomarkers of neurodegeneration in diabetic retinopathy]. [糖尿病视网膜病变神经退行性变的生物标志物]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-02-12 DOI: 10.1007/s00347-025-02201-1

Thiago Gonçalves Dos Santos Martins, Diogo Gonçalves Dos Santos Martins

引用次数: 0

[Intraocular pressure rise, hyphema and uveitis in chronic lymphocytic leukemia undergoing ibrutinib treatment]. [依鲁替尼治疗慢性淋巴细胞白血病并发眼压升高、前房积血和葡萄膜炎]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-01-27 DOI: 10.1007/s00347-024-02177-4

Abdelrahman Assaf, Fidan Aghayeva, Ines M Lanzl

引用次数: 0

[Symptomatic Rathke's cyst of the pituitary gland-When the eye uncovers the invisible]. [有症状的Rathke脑垂体囊肿-当眼睛发现了看不见的东西]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-02-06 DOI: 10.1007/s00347-025-02182-1

A Struppe, Alaadin Abdin, Berthold Seitz, Loïc Hamon

引用次数: 0

Mitteilungen der DOG. 狗的信息。

Die Ophthalmologie Pub Date : 2025-04-01 DOI: 10.1007/s00347-025-02229-3

引用次数: 0

[EyeMatics-Multicenter data evaluation of real-world data with interoperable medical informatics]. [EyeMatics--利用可互操作的医疗信息学对真实世界数据进行多中心数据评估]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2024-11-14 DOI: 10.1007/s00347-024-02135-0

Lea Holtrup, Julian Varghese, Alexander K Schuster, Broder Poschkamp, Christopher Hampf, Dagmar Waltemath, Leonie Wahle, Myriam Lipprandt, David A Merle, Philipp Berens, Oliver Kohlbacher, Vinodh Kakkassery, Martin Bartos, Focke Ziemssen, Thomas Wendt, Katja Hoffmann, Nicole Eter

{"title":"[EyeMatics-Multicenter data evaluation of real-world data with interoperable medical informatics].","authors":"Lea Holtrup, Julian Varghese, Alexander K Schuster, Broder Poschkamp, Christopher Hampf, Dagmar Waltemath, Leonie Wahle, Myriam Lipprandt, David A Merle, Philipp Berens, Oliver Kohlbacher, Vinodh Kakkassery, Martin Bartos, Focke Ziemssen, Thomas Wendt, Katja Hoffmann, Nicole Eter","doi":"10.1007/s00347-024-02135-0","DOIUrl":"10.1007/s00347-024-02135-0","url":null,"abstract":"The evaluation of real-world data (RWD) enables insights to be gained from a wide range of patient data collected in routine clinical practice. In addition, multicenter analyses represent a broad and representative patient population and have the potential to capture the actual treatment situation. As a basis for this, the definition of datasets and an infrastructure for data exchange is necessary. Data integration centers (DIC) have already been established at (university) hospitals throughout Germany in order to extract RWD for scientific analyses from the various source systems and integrate them into research-compatible data infrastructures. The project described here aims to demonstrate the added value of this data integration using a case of application in ophthalmology, defining a core dataset as an ophthalmology extension module and establishing a cross-site data exchange infrastructure. As a first step, the treatment success of eye diseases treated with intravitreal injection (IVI) should be improved. To achieve this goal a dashboard for clinical data is provided that clearly visualizes the merged data. Furthermore, algorithms will be developed to identify new imaging biomarkers that can be used for treatment monitoring and predict treatment outcomes.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"270-277"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Secondary calcification of a multifocal additive intraocular lens]. [多焦人工晶状体继发性钙化]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-02-24 DOI: 10.1007/s00347-025-02203-z

Lars H B Mackenbrock, Timur M Yildirim, Gerd U Auffarth, Ramin Khoramnia

引用次数: 0

[Artificial intelligence in medicine-Opportunities and risks from an ethical perspective]. [医学中的人工智能——从伦理角度看的机遇和风险]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-04-02 DOI: 10.1007/s00347-025-02224-8

Saskia Metan, Florian Bruns

引用次数: 0

[MiHUBx: a digital progress hub for the use of intersectoral clinical data sets using the example of diabetic macular edema]. [MiHUBx：以糖尿病性黄斑水肿为例，使用跨部门临床数据集的数字进展中心]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2024-12-18 DOI: 10.1007/s00347-024-02146-x

Gabriel Stolze, Vinodh Kakkassery, Danny Kowerko, Martin Bartos, Katja Hoffmann, Martin Sedlmayr, Katrin Engelmann

{"title":"[MiHUBx: a digital progress hub for the use of intersectoral clinical data sets using the example of diabetic macular edema].","authors":"Gabriel Stolze, Vinodh Kakkassery, Danny Kowerko, Martin Bartos, Katja Hoffmann, Martin Sedlmayr, Katrin Engelmann","doi":"10.1007/s00347-024-02146-x","DOIUrl":"10.1007/s00347-024-02146-x","url":null,"abstract":"Background: Evidence-based treatment recommendations are helpful in the corresponding discipline-specific treatment but can hardly take data from real-world care into account. In order to make better use of this in everyday clinical practice, including with respect to predictive statements about disease development or treatment success, models with data from treatment must be developed in order to use them for the development of assistive artificial intelligence.Goal: The aim of the Use Case 1 of the medical informatics hub in Saxony (MiHUBx) is the development of a model based on treatment and research data for a treatment algorithm supported by biomarkers and also the development of the necessary digital infrastructure.Material and methods: Step by step, the necessary partners in hospitals and practices will be brought together technically or through research questions within Use Case 1 \"Ophthalmology meets Diabetology\", a regional digital progress hub in health, the medical informatics hub in Saxony (MiHUBx ) of the nationwide medical informatics initiative (MII).Results: Based on joint studies with diabetologists, robust serological and imaging biomarkers were selected that provide evidence of the development of diabetic macular edema (DME). In the future, these and other scientifically proven prognostic markers will be incorporated into a treatment algorithm that is supported by artificial intelligence (AI). For this purpose, model procedures are being developed together with medical informatics specialists. At the same time, a data integration center (DIZ) was established.Conclusion: In addition to the structured and technical combination of the previously disseminated and partially heterogeneous treatment data, the Use Case 1 defines the chances and hurdles for using such real-world data to develop artificial intelligence.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"262-269"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0