Die Ophthalmologie最新文献_第10页

[Julius Springer Prize for Ophthalmology 2024 : Dr. Mael Lever honored for outstanding original paper]. [2024 年朱利叶斯-施普林格眼科奖：Mael Lever 博士因发表杰出原创论文而获奖]。

Die Ophthalmologie Pub Date : 2024-10-24 DOI: 10.1007/s00347-024-02133-2

Michal Marie Meyer Zu Tittingdorf

引用次数: 0

[Bilateral fibrinous iridocyclitis with extensive myopization]. [双侧纤维素性虹膜睫状体炎伴广泛近视]。

Die Ophthalmologie Pub Date : 2024-10-01 Epub Date: 2024-08-07 DOI: 10.1007/s00347-024-02087-5

Peter Werkl, Gerald Seidel, Christoph Singer, Hrvoje Tomasic, Tobias Peschaut, Astrid Heidinger, Katharina Valentin, Michael Sommer

引用次数: 0

[Pathogenesis of Fuchs endothelial corneal dystrophy, the fibrillar layer and individualized treatment]. [福氏内皮角膜营养不良症的发病机制、纤维层和个体化治疗]。

Die Ophthalmologie Pub Date : 2024-10-01 DOI: 10.1007/s00347-024-02123-4

Antonia Howaldt, Thomas Clahsen, Mert Mestanoglu, Margarete Odenthal, Volkan Tahmaz, Claus Cursiefen, Mario Matthaei

{"title":"[Pathogenesis of Fuchs endothelial corneal dystrophy, the fibrillar layer and individualized treatment].","authors":"Antonia Howaldt, Thomas Clahsen, Mert Mestanoglu, Margarete Odenthal, Volkan Tahmaz, Claus Cursiefen, Mario Matthaei","doi":"10.1007/s00347-024-02123-4","DOIUrl":"10.1007/s00347-024-02123-4","url":null,"abstract":"Fuchs endothelial corneal dystrophy (FECD) is a genetic and age-associated corneal disease characterized by an accelerated loss of corneal endothelial cells and an increased subendothelial deposition of extracellular matrix (ECM). Clinically, advanced disease leads to corneal edema with subsequent reduction in visual acuity. In the majority of patients with advanced FECD, a fibrillar layer (FL) appears on the posterior corneal surface. This FL is mostly localized in the inferotemporal corneal quadrant, marks areas with significantly reduced endothelial cell density and increased corneal thickness in the sense of edema and can be visualized and measured using Scheimpflug backscatter analysis due to increased backscatter. FECD is currently the most common indication for corneal transplantation worldwide, usually in the form of Descemet membrane endothelial keratoplasty (DMEK). New treatment approaches include variations of DMEK surgery such as hemi- or quarter DMEK with individualized and smaller grafts or Descemet membrane stripping only (DSO). In the future, clinical imaging of the FL as a particularly affected endothelial area could be important for FECD progression assessment and planning of surgical interventions. This article provides an overview of the current state of research on the clinical aspects, pathogenesis, fibrillar layer and individualized treatment of FECD.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"787-795"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[How to talk to relatives about corneal donation]. [如何与亲属谈论角膜捐献]。

Die Ophthalmologie Pub Date : 2024-10-01 Epub Date: 2024-09-23 DOI: 10.1007/s00347-024-02111-8

Roberto D'Amelio, Loïc Hamon, Berthold Seitz, Isabel Weinstein

引用次数: 0

[Enucleations, eviscerations and orbital implants in German eye hospitals]. [德国眼科医院的去核、切除和眼眶植入手术]。

Die Ophthalmologie Pub Date : 2024-10-01 Epub Date: 2024-08-09 DOI: 10.1007/s00347-024-02088-4

Anna Schuh, Nicolas Pensel, Siegfried Priglinger, Christoph Hintschich

引用次数: 0

[Rosette-shaped coatings on the anterior surface of the lens after silicone oil implantation]. [硅油植入术后晶状体前表面的玫瑰花状涂层]。

Die Ophthalmologie Pub Date : 2024-10-01 Epub Date: 2024-07-25 DOI: 10.1007/s00347-024-02081-x

Maximilian Berger, Fabian Norbert Fries, Berthold Seitz

引用次数: 0

[EndoArt®: results in patients with glaucoma drainage devices]. [EndoArt®：患者使用青光眼引流装置的结果]。

Die Ophthalmologie Pub Date : 2024-10-01 Epub Date: 2024-10-02 DOI: 10.1007/s00347-024-02122-5

Johanna Wiedemann, Mert Mestanoglu, Anne Rekate, Caroline Gietzelt, Claus Cursiefen, Björn Bachmann

{"title":"[EndoArt®: results in patients with glaucoma drainage devices].","authors":"Johanna Wiedemann, Mert Mestanoglu, Anne Rekate, Caroline Gietzelt, Claus Cursiefen, Björn Bachmann","doi":"10.1007/s00347-024-02122-5","DOIUrl":"10.1007/s00347-024-02122-5","url":null,"abstract":"Background: EndoArt® (Eye Yon Medical, Ness Ziona, Israel) is a novel artificial corneal inner layer transplant and an innovative treatment alternative for patients at high risk for graft failure after posterior lamellar corneal transplantation (EK).Aim of the study: We present the initial results of the EndoArt® implantation in patients with glaucoma drainage devices (GDD).Patients and surgical procedure: In this study 12 eyes with GDD were retrospectively evaluated. All had a high risk of transplant rejection in cases of EK (previous other glaucoma surgery in addition to GDD, n = 8, condition following Descemet membrane endothelial keratoplasty, DMEK, n = 9, uveitis, n = 2, or synechiae, n = 2). The EndoArt® was secured with a gas bubble and one to three holding sutures. The preoperative and postoperative best spectacle-corrected visual acuity (BSCVA) and central corneal thickness (CCT) were determined. The need for additional gas injections (rebubbling) was analyzed.Results: Octafluoropropane (C3F8) 12% was used in nine patients and sulfur hexafluoride (SF6) 20% in three patients as anterior chamber tamponade to ensure adhesion of the EndoArt®. At least one rebubbling was necessary in four eyes. The preoperative BSCVA was 1.6 (± 0.5) logMAR and significantly improved to 1.1 (± 0.6) logMAR after 12 weeks (p = 0.028). The preoperative CCT was 719 µm ± 145.7, which significantly decreased to 622.4 µm ± 174.9 after six weeks (p = 0.004) and to 591.7 µm ± 190.8 after 12 weeks (p = 0.096). In one eye, the prosthesis was explanted due to a suspected fibrotic remodelling of the cornea following multiple previous DMEKs.Discussion: EndoArt® led to a significant improvement in BSCVA and reduction in CCT; however, there was a high rebubbling rate in patients with GDD. In high-risk patients, the use of EndoArt® may be advantageous in avoiding graft failure after EK.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"803-813"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Digital remote monitoring of chronic retinal conditions-A clinical future tool? : Remote monitoring of chronic retinal conditions]. [慢性视网膜病症的数字远程监控--未来的临床工具？ : 慢性视网膜病症的远程监控]。

Die Ophthalmologie Pub Date : 2024-10-01 Epub Date: 2024-09-14 DOI: 10.1007/s00347-024-02109-2

Jan Henrik Terheyden, Matthias M Mauschitz, Maximilian W M Wintergerst, Petrus Chang, Philipp Herrmann, Raffael Liegl, Thomas Ach, Robert P Finger, Frank G Holz

{"title":"[Digital remote monitoring of chronic retinal conditions-A clinical future tool? : Remote monitoring of chronic retinal conditions].","authors":"Jan Henrik Terheyden, Matthias M Mauschitz, Maximilian W M Wintergerst, Petrus Chang, Philipp Herrmann, Raffael Liegl, Thomas Ach, Robert P Finger, Frank G Holz","doi":"10.1007/s00347-024-02109-2","DOIUrl":"10.1007/s00347-024-02109-2","url":null,"abstract":"Background: In view of the predicted increase in incidence and prevalence of chronic retinal diseases and undersupply of care in the population, telemedicine could contribute to reducing access barriers to healthcare and improving the results of treatment.Objective: A literature review on remote monitoring of chronic retinal diseases was carried out.Material and methods: The medical literature was searched for publications on remote monitoring of chronic retinal diseases. The results were compiled in a narrative overview.Results: The four main topics in the literature are: validation studies, implementation strategies, acceptance/target group analyses and health economic analyses. Remote monitoring systems are based on visual function tests, imaging or patient reports and have been particularly investigated in age-related macular degeneration (AMD) and diabetic eye disease (DED). Studies indicate positive effects regarding an optimization of clinical care and a favorable safety profile but randomized controlled trials are lacking for the majority of monitoring tools.Conclusion: Remote monitoring could complement existing care structures for patients with chronic retinal diseases, especially AMD and DED. Promising systems are based on hyperacuity or optical coherence tomography, while patient-reported data are not commonly used; however, there is currently insufficient evidence justifying the use of remote monitoring systems in chronic retinal diseases in Europe and more research on the validation of remote monitoring systems is needed.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"826-834"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Innovative surgical treatment approaches for endothelial dysfunction : Descemet stripping only (DSO) and endothelial cell injection]. [内皮功能障碍的创新手术治疗方法：单纯去骨瓣剥离术（DSO）和内皮细胞注射术]。

Die Ophthalmologie Pub Date : 2024-10-01 Epub Date: 2024-10-11 DOI: 10.1007/s00347-024-02119-0

V Tahmaz, M Mestanoğlu, A Howaldt, B O Bachmann, M Matthaei, C Cursiefen

{"title":"[Innovative surgical treatment approaches for endothelial dysfunction : Descemet stripping only (DSO) and endothelial cell injection].","authors":"V Tahmaz, M Mestanoğlu, A Howaldt, B O Bachmann, M Matthaei, C Cursiefen","doi":"10.1007/s00347-024-02119-0","DOIUrl":"10.1007/s00347-024-02119-0","url":null,"abstract":"Currently, due to a rising number of patients Germany and many other countries experience a large deficit of donor eyes for posterior lamellar keratoplasty procedures in the treatment of corneal endothelial diseases. To address this unmet need there is an ongoing investigation of treatment modalities which do not rely on donor tissue or enable clinicians to treat more patient eyes per donor eye. The authors introduce a promising approach for both treatment principles. First, the technique of Descemet stripping only (DSO) is detailed, in which a central part of the Descemet's membrane including the endothelium is surgically removed without replacement with donor tissue. This then allows endothelial cells from the periphery of the cornea to migrate into the central area and can reduce corneal opacification and swelling. As a representative technique of the second group, the authors introduce endothelial cell injection, in which human corneal endothelial cells are cultivated in vitro and then, after removal of the diseased endothelium, injected into the anterior chamber of the recipient's eye to form a new and healthy endothelium. This is supported by injection of Rho kinase inhibitors and a face-down positioning of the patient after surgery. It is postulated that endothelial cell injection could possibly enable clinicians to treat up to 300 patient eyes with the tissue generated from 1 donor eye. Whether and how these novel approaches will become established in Europe remains to be seen.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"796-802"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abstractband DOG 2024. Abstband DOG 2024。

Die Ophthalmologie Pub Date : 2024-10-01 DOI: 10.1007/s00347-024-02107-4

引用次数: 0