Die Ophthalmologie最新文献

[Morphological and functional changes of secondary macular neovascularization in central serous chorioretinopathy under anti-VEGF treatment]. [抗血管内皮生长因子治疗下中心性浆液性脉络膜视网膜病变继发性黄斑新生血管的形态和功能变化]。

Die Ophthalmologie Pub Date : 2025-04-08 DOI: 10.1007/s00347-025-02221-x

Nikolai Kleefeldt, Sophia Kuehnel, Lukas Reiser, Winfried Goebel, Jost Hillenkamp, Antony William

{"title":"[Morphological and functional changes of secondary macular neovascularization in central serous chorioretinopathy under anti-VEGF treatment].","authors":"Nikolai Kleefeldt, Sophia Kuehnel, Lukas Reiser, Winfried Goebel, Jost Hillenkamp, Antony William","doi":"10.1007/s00347-025-02221-x","DOIUrl":"https://doi.org/10.1007/s00347-025-02221-x","url":null,"abstract":"Background: Investigation of the morphological changes by optical coherence tomography angiography (OCT-A) and the development of visual acuity in secondary macular neovascularization (sMNV) in central serous chorioretinopathy (CCS) during anti-vascular endothelial growth factor (VEGF) treatment.Patients and methods: Retrospective study of all treatment-naïve eyes with respect to anti-VEGF treatment, in which sMNV in CCS was detected by fluorescein angiography (FA) and OCT‑A and which were treated at the University Eye Hospital Würzburg between July 2021 and the end of December 2022. All patients were treated according to a pro re nata injection regimen (PRN regimen) and followed up for 1 year.Results: In the study 20 eyes from 16 patients with sMNV in CCS were included. Using FA the sMNV could be confirmed in 35% of cases and using OCT‑A in 100% of cases. Morphologically, the sMNV was clearly demarcated by OCT‑A as \"sea-fan\"-like in 10 eyes and filamentous in 10 eyes. The decrease in area of the sMNV from 0.94 ± 1.2 mm2 at baseline to 0.72 ± 0.82 mm2 at 12 months was not statistically significant (p = 0.12). During the observational period an average of 8.7 ± 1.6 intravitreal injections (IVOM) were administered (5-12 IVOM, median 9 IVOM).Discussion: Both FA and OCT‑A were used to detect sMNV in CCS, with OCT‑A providing more reliable detection of sMNV than FA. With OCT‑A two different types of sMNV could be detected: 1) the \"sea-fan\" type and 2) the filamentous MNV type. Within the first year of treatment sMNV in CCS requires a comparable number of IVOMs as the treatment of neovascular age-related macular degeneration.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Morgagnian cataract]. (Morgagnian白内障)。

Die Ophthalmologie Pub Date : 2025-04-02 DOI: 10.1007/s00347-025-02219-5

Philip Wakili, Karl Boden, Peter Szurman, Paul Schütte, Clemens N Rudolph

引用次数: 0

[Digitalization and artificial intelligence in ophthalmology-Is the matrix not far off?] 数字化与人工智能在眼科的应用——矩阵不远了吗？］

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-04-08 DOI: 10.1007/s00347-025-02226-6

Vinodh Kakkassery, Katrin Engelmann

引用次数: 0

[Cataract surgery in sub-Saharan Africa-Possibilities and limits]. 【撒哈拉以南非洲的白内障手术——可能性与局限性】。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-03-06 DOI: 10.1007/s00347-025-02195-w

Stephan Irle, Hanne Irle, Rohil Paes, Piet Noë

{"title":"[Cataract surgery in sub-Saharan Africa-Possibilities and limits].","authors":"Stephan Irle, Hanne Irle, Rohil Paes, Piet Noë","doi":"10.1007/s00347-025-02195-w","DOIUrl":"10.1007/s00347-025-02195-w","url":null,"abstract":"Background: The importance of cataract surgery for the treatment of visual impairment and blindness is as uncontroversial as the cost-effectiveness of the procedure. In terms of quality, there are almost no published case series of cataract operations in sub-Saharan Africa that meet the World Health Organization (WHO) guidelines for postoperative visual acuity.Objective: The results after cataract surgery at a publicly accessible tertiary care eye clinic in Rwanda are presented and compared with standardized results from an eye clinic in Germany (AKW).Methods: Data from 100 consecutive eyes (manual small incision cataract surgery, MSICS-Rwanda, Phaco-Rwanda, Phaco-AKW) were retrospectively evaluated. The results were compared with each other and with WHO guidelines.Results: The number of patients with significantly reduced preoperative visual acuity (visual acuity > 1.3 logMAR) was highest in the MSICS group (MSICS 92%, Phaco-Rwanda 13%, Phaco-AKW 1%). Uncorrected postoperative visual acuity was similar in the Phako-Rwanda and Phako-AKW groups (0.22/0.21 logMAR) and better than MSICS Rwanda (0.33 logMAR). The best corrected postoperative visual acuity was significantly better in the Phako-Rwanda group (0.07 logMAR) than in the two comparison groups Phako-AKW (0.1 logMAR) and MSICS Rwanda (0.15 logMAR). The results of all three groups fulfilled the WHO criteria for postoperative visual acuity.Conclusion: Despite poor initial visual acuity, high quality results can be achieved in cataract surgery in a clinical setting in sub-Saharan Africa that are within WHO expectations. A coexistence of MSICS technique and phaco seems reasonable to avoid complications and achieve the best possible results.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"288-296"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Residual intravitreal PFCL]. [玻璃体内残留PFCL]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-03-17 DOI: 10.1007/s00347-025-02202-0

Helin Arda, Christos Haritoglou

引用次数: 0

[Change in the use of data for research-A hurdle race for medicine?] 研究数据使用的改变——医学的跨栏赛跑？］

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-01-07 DOI: 10.1007/s00347-024-02161-y

Katrin Engelmann, Vinodh Kakkassery, Gabriel Stolze, Jens Weidner, Martin Sedlmayr

引用次数: 0

[Bilateral conspicuous iris configuration and elevation of intraocular pressure of unclear origin]. [双侧虹膜形态明显，眼压升高原因不明]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-01-13 DOI: 10.1007/s00347-024-02178-3

Lukas Schloesser, Robert P Finger, Somar Hasan

引用次数: 0

[Etiology of pediatric ocular trauma in a tertiary referral hospital in Tanzania]. [坦桑尼亚一家三级转诊医院的儿童眼外伤病因学]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-02-28 DOI: 10.1007/s00347-025-02194-x

Patrizia Krauss, Heiko Philippin, Karin M Knoll, Matthias Eidel, Martin M Nentwich, Peter Shah, Freda Sii, Evarista Mgaya, Furahini G Mndeme, Christopher Mwanansao

{"title":"[Etiology of pediatric ocular trauma in a tertiary referral hospital in Tanzania].","authors":"Patrizia Krauss, Heiko Philippin, Karin M Knoll, Matthias Eidel, Martin M Nentwich, Peter Shah, Freda Sii, Evarista Mgaya, Furahini G Mndeme, Christopher Mwanansao","doi":"10.1007/s00347-025-02194-x","DOIUrl":"10.1007/s00347-025-02194-x","url":null,"abstract":"Background: Ocular trauma in childhood is a major cause of unilateral acquired blindness in Africa [3]. The aim of the study was to identify the underlying mechanisms of injury in order to develop region-specific prevention strategies.Patients and methods: The study was performed at the Department of Ophthalmology of Bugando Medical Centre in Mwanza, Tanzania, during a 3-month observation period in spring 2019. All children under the age of 17 years who presented with acute eye injury or a history of ocular trauma within 4 years prior to presentation were included. The data collection was performed using a standardized questionnaire based on the UK Paediatric Ocular Trauma Study I, which was adapted to the specific local conditions.Results: We included 49 patients. The mean age at the time of injury was 7 years. Boys were affected more often than girls (69% vs. 31%). The most frequent objects causing injury were wooden sticks (45%). The majority of the injuries happened at home (51%). Only 35% of the patients presented at an eye unit within 24 h after the injury, while 26% waited longer than 7 days. The most common clinical finding was corneal laceration (73%) and 33 patients needed immediate surgical treatment.Conclusion: Ocular trauma in children is a frequent and important ophthalmological issue in Tanzania. To prevent these injuries, more public education concerning adult supervision and eye protection is needed. Furthermore, it is important to raise awareness about the need for an immediate presentation at an eye unit, which can help to achieve a better visual outcome.","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"297-303"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Biomarkers of neurodegeneration in diabetic retinopathy]. [糖尿病视网膜病变神经退行性变的生物标志物]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-02-12 DOI: 10.1007/s00347-025-02201-1

Thiago Gonçalves Dos Santos Martins, Diogo Gonçalves Dos Santos Martins

引用次数: 0

[Symptomatic Rathke's cyst of the pituitary gland-When the eye uncovers the invisible]. [有症状的Rathke脑垂体囊肿-当眼睛发现了看不见的东西]。

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-02-06 DOI: 10.1007/s00347-025-02182-1

A Struppe, Alaadin Abdin, Berthold Seitz, Loïc Hamon

引用次数: 0