Die Ophthalmologie最新文献

{"title":"[Artificial intelligence in medicine-Opportunities and risks from an ethical perspective].","authors":"Saskia Metan, Florian Bruns","doi":"10.1007/s00347-025-02224-8","DOIUrl":"https://doi.org/10.1007/s00347-025-02224-8","url":null,"abstract":"<p><p>Imaging disciplines, such as ophthalmology, offer a wide range of opportunities for the beneficial use of artificial intelligence (AI). The analysis of images and data by trained algorithms has the potential to facilitate making the diagnosis and patient care and not just in ophthalmology. If AI brings about advances in clinical practice that benefit patients, this is ethically to be welcomed; however, respect for the self-determination of patients and data security must be guaranteed. Traceability and explainability of the algorithms would strengthen trust in automated decision-making and enable ultimate medical responsibility. It should be noted that algorithms are only as good and unbiased as the data used to train them. If the use of AI is likely to lead to a loss of skills on the part of doctors (deskilling), this must be counteracted, for example through improved training. Accompanying medical ethics research is necessary to identify those aspects of the use of AI that require regulation. In principle, care must be taken to ensure that AI serves people and adapts to their needs, not the other way round.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Uveal effusion syndrome due to immune-mediated reaction to pembrolizumab].","authors":"V Schöneberger, J Schätzel, L Kinzel, F Schaub, T A Fuchsluger, C Brockmann","doi":"10.1007/s00347-025-02215-9","DOIUrl":"https://doi.org/10.1007/s00347-025-02215-9","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Complaints and complications after intravitreal injection (IVI) and potential risk factors].","authors":"Lisa Prange, Daniel Böhringer, Thomas Reinhard, Hansjürgen Agostini, Felicitas Bucher","doi":"10.1007/s00347-025-02222-w","DOIUrl":"https://doi.org/10.1007/s00347-025-02222-w","url":null,"abstract":"<p><strong>Background: </strong>Intravitreal injections (IVI) are the most commonly used procedure worldwide in the treatment of retinal vascular diseases.</p><p><strong>Objective: </strong>This study investigates the endophthalmitis rate, the frequency of subjective complaints and potential risk factors associated with IVI.</p><p><strong>Material and methods: </strong>In the first part of this monocentric study the number of cases of endophthalmitis and potential risk factors were analyzed based on routine hospital documentation of 123,373 IVI procedures from 2013 to 2022. In the second part, subjective complaints and potential risk factors following IVI were investigated through a survey involving 584 patients.</p><p><strong>Results: </strong>From 2013 to 2022 a total of 27 cases of endophthalmitis occurred following IVI (0.02%). The analysis of potential risk factors (age, gender, disinfection method, number of prior injections, day of the week, year, bilateral injection) revealed that none of these factors were associated with an increased risk of endophthalmitis. The initial identification of bilateral injection as a risk factor was disproven through further analysis and classified as a statistical artifact. More than 10% of patients reported complaints the day after the injection, such as foreign body sensation (18%), seeing air bubbles (17%), itching (12%) and reddening of the eyes (11%). Subconjunctival hemorrhage (4%) or severe pain the day after the injection (2%) occurred less frequently. Male patients reported severe pain the day after less often (odds ratio 0.18, 95% confidence interval 0.03-0.72). Nearly 2% of patients sought unplanned ophthalmologist visits or considered treatment discontinuation due to the complaints.</p><p><strong>Conclusion: </strong>Subjective complaints are more prevalent than severe complications and can jeopardize treatment adherence. Therefore, providing information about expected discomfort is advisable.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ocular graft versus host disease].","authors":"Philipp Steven, Tina Dietrich-Ntoukas","doi":"10.1007/s00347-025-02212-y","DOIUrl":"https://doi.org/10.1007/s00347-025-02212-y","url":null,"abstract":"<p><p>Ocular graft versus host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (HSCT) is predominantly an inflammatory and destructive ocular surface disease with increasing incidence. It not only leads to a reduced quality-of-life but can also impair vision and in severe cases lead to blindness. The occurrence of GVHD can lead to a severe, often refractory disorders of the ocular surface, which is associated with chronic inflammation. The occurrence of corneal involvement is a major problem. The establishment of comprehensive care structures and individually adapted stage-appropriate treatment in interdisciplinary collaboration with colleagues in hemato-oncology is therefore of particular importance.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Unilateral gonococcal keratoconjunctivitis].","authors":"M Kogan, B Book, E Sokolenko, D Brockmann, C Framme, J Tode","doi":"10.1007/s00347-025-02218-6","DOIUrl":"https://doi.org/10.1007/s00347-025-02218-6","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Current trends in the treatment of rhegmatogenous retinal detachment and perioperative positioning strategies in Germany: results of a retina.net survey].","authors":"Piotr Strzalkowski, Alicja Strzalkowska, Andreas Stahl, Alexander K Schuster, Sema Kaya, Mathias Roth, Tim U Krohne, Robert P Finger, Friederike Schaub, Stefan Dithmar, Carsten Framme, Armin Wolf, Martin Spitzer, Hansjürgen Agostini, Nicolas Feltgen, Oliver Zeitz, Julian Klaas, Jost Hillenkamp, Amelie Pielen, Horst Helbig, Salvatore Grisanti, Hans Hoerauf, Nikolaos E Bechrakis, Peter Walter, Johann Roider, Jens Schrecker, Thomas Ach, Teresa Barth, Jan Tode, Gerd Geerling, Rainer Guthoff","doi":"10.1007/s00347-025-02216-8","DOIUrl":"https://doi.org/10.1007/s00347-025-02216-8","url":null,"abstract":"<p><strong>Background: </strong>Rhegmatogenous retinal detachment (RRD) is an ophthalmological emergency with an increasing incidence in Germany. Despite established methods, perioperative positioning is important to improve outcomes and avoid complications but may be challenging, particularly in immobile patients. An analysis of the current trends in surgical treatment and perioperative positioning practices for RRD in Germany compared to historical data from 2018 is essential.</p><p><strong>Material and methods: </strong>An online survey with five hypothetical cases of acute RRD was distributed to vitreoretinal surgeons via the retina.net research network. A total of 27 questionnaires were analyzed focusing on participant demographic data, surgical techniques, anesthesia types, perioperative positioning and aftercare strategies.</p><p><strong>Results: </strong>Of the respondents 50% were over 50 years old, 86% worked at university eye clinics and 89% had performed over 1000 vitreoretinal procedures. For RRD in the temporal upper quadrant, preoperative and postoperative temporal lateral positioning is recommended. Of the respondents 86% consider postoperative positioning crucial to prevent macular folds. Complete subretinal fluid drainage is favored by 82% and 23 G trocars were used by 77%. For phakic eyes with uncomplicated RRD 86% chose buckling surgery, while 50% opted for silicone oil in complex inferior RRD cases. General anesthesia was preferred by 61%, always in an in-patient setting.</p><p><strong>Conclusion: </strong>Preoperative and postoperative temporal lateral positioning followed by prone positioning is favored for temporal upper quadrant RRD, whereas no specific positioning is recommended for inferior RRD managed with silicone oil or buckling surgery. Postoperative positioning after pars plana vitrectomy (ppV) and gas endotamponade is considered by 86% to be decisive in preventing macular folds. The 23 G trocar system remains the preferred choice despite smaller alternatives. In certain cases buckling is still of importance.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Spontaneous visual improvement after DMEK despite transplant dislocation].","authors":"Broder Poschkamp, Andreas Stahl, Marie-Christine Bründer","doi":"10.1007/s00347-025-02214-w","DOIUrl":"https://doi.org/10.1007/s00347-025-02214-w","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Sequential toric IOL implantation after phakic DMEK due to secondary transplant failure after perforating keratoplasty with high corneal astigm].","authors":"A Struppe, B Seitz, L Daas, L Hamon","doi":"10.1007/s00347-025-02217-7","DOIUrl":"https://doi.org/10.1007/s00347-025-02217-7","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Retinopathy of prematurity in a pair of premature twins-A discordant case].","authors":"Stefanie Gniesmer, Viktorija Belousova, Roya Piria, Julius Caspar Rotering, Guido Stichtenoth, Malte Spielmann, Andreas Stahl, Salvatore Grisanti","doi":"10.1007/s00347-025-02220-y","DOIUrl":"https://doi.org/10.1007/s00347-025-02220-y","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Intrasaccal foreign body after lacrimal duct surgery-A relic from the past?]","authors":"Julian Zimmermann, Nicole Eter, Ralph-Laurent Merté","doi":"10.1007/s00347-025-02211-z","DOIUrl":"https://doi.org/10.1007/s00347-025-02211-z","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}