Dementia and neurocognitive disorders最新文献_第8页

Comparison of RCF Scoring System to Clinical Decision for the Rey Complex Figure Using Machine-Learning Algorithm. 利用机器学习算法比较雷伊复杂图形的 RCF 评分系统与临床决策。

Dementia and neurocognitive disorders Pub Date : 2021-10-01 Epub Date: 2021-10-31 DOI: 10.12779/dnd.2021.20.4.70

Chanda Simfukwe, Seong Soo An, Young Chul Youn

{"title":"Comparison of RCF Scoring System to Clinical Decision for the Rey Complex Figure Using Machine-Learning Algorithm.","authors":"Chanda Simfukwe, Seong Soo An, Young Chul Youn","doi":"10.12779/dnd.2021.20.4.70","DOIUrl":"10.12779/dnd.2021.20.4.70","url":null,"abstract":"Background and purpose: Interpreting the Rey complex figure (RCF) requires a standard RCF scoring system and clinical decision by clinicians. The interpretation of RCF using clinical decision by clinicians might not be accurate in the diagnosing of mild cognitive impairment (MCI) or dementia patients in comparison with the RCF scoring system. For this reason, a machine-learning algorithm was used to demonstrate that scoring RCF using clinical decision is not as accurate as of the RCF scoring system in predicting MCI or mild dementia patients from normal subjects.Methods: The RCF dataset consisted of 2,232 subjects with formal neuropsychological assessments. The RCF dataset was classified into 2 datasets. The first dataset was to compare normal vs. abnormal and the second dataset was to compare normal vs. MCI vs. mild dementia. Models were trained using a convolutional neural network for machine learning. Receiver operating characteristic curves were used to compare the sensitivity, specificity, and area under the curve (AUC) of models.Results: The trained model's accuracy for predicting cognitive states was 96% with the first dataset (normal vs. abnormal) and 88% with the second dataset (normal vs. MCI vs. mild dementia). The model had a sensitivity of 85% for detecting abnormal with an AUC of 0.847 with the first dataset. It had a sensitivity of 78% for detecting MCI or mild dementia with an AUC of 0.778 with the second dataset.Conclusions: Based on this study, the RCF scoring system has the potential to present more accurate criteria than the clinical decision for distinguishing cognitive impairment among patients.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 4","pages":"70-79"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1d/dc/dnd-20-70.PMC8585537.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39637468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurosyphilis as a Rare Cause of Mild Cognitive Impairment and Depression: Two Case Reports and Literature Review. 神经梅毒是一种罕见的引起轻度认知障碍和抑郁的原因:两例报告和文献复习。

Dementia and neurocognitive disorders Pub Date : 2021-10-01 Epub Date: 2021-10-20 DOI: 10.12779/dnd.2021.20.4.112

Kyung Won Lee, Yun Jeong Hong, Si Baek Lee, Seong Hoon Kim, Yun Sang Oh, Yongbang Kim, Jeong Wook Park

引用次数: 1

A Comparison of the Performance between the 60- and 120-Second Conditions of the Korean-Color Word Stroop Test: Color Reading (K-CWST: CR). 韩文颜色词Stroop测验:颜色阅读(K-CWST: CR) 60秒和120秒条件下的表现比较

Dementia and neurocognitive disorders Pub Date : 2021-10-01 Epub Date: 2021-10-21 DOI: 10.12779/dnd.2021.20.4.62

Sun Hwa Lee, Yeonwook Kang, Minji Song, Geon Ha Kim, Jee Hyang Jeong

{"title":"A Comparison of the Performance between the 60- and 120-Second Conditions of the Korean-Color Word Stroop Test: Color Reading (K-CWST: CR).","authors":"Sun Hwa Lee, Yeonwook Kang, Minji Song, Geon Ha Kim, Jee Hyang Jeong","doi":"10.12779/dnd.2021.20.4.62","DOIUrl":"https://doi.org/10.12779/dnd.2021.20.4.62","url":null,"abstract":"Background and purpose: The Korean-Color Word Stroop Test: Color Reading (K-CWST: CR) included in the Seoul Neuropsychological Screening Battery, 2nd Edition (SNSB-II) examines inhibitory control deficit. It provides normative data for both 60- and 120-second conditions, but the validity of the 60-second condition has not yet been proven. This study examined the validity of the 60-second condition by observing concordance between the performances in cognitively normal, MCI, and mild dementia groups.Methods: There were 1,336 patients performed the SNSB-II, including the K-CWST: CR. Based on the cognitive test results, activities of daily living, and clinical interview, the patients were assigned to normal cognition (n=104), MCI (n=884), or mild dementia (n=348) groups. Abnormal performance on the K-CWST: CR was operationally defined as 1SD below the normative mean. The receiver operating characteristic curve analyses were conducted to compare the discriminability between the 60- and 120-second conditions.Results: The percentages of abnormal performance in the MCI group were 41.5% and 42.3%, and those in the mild dementia group were 82.7% and 82.4% for the 60- and 120-second conditions, respectively. The areas under the curve for the 60- and 120-seconds were as follows; 0.80 and 0.81 in differentiating normal from MCI; 0.95 and 0.96 in normal from mild dementia; and 0.77 and 0.77 in MCI from mild dementia.Conclusions: The 60-second condition of the K-CWST showed very similar results, not statistically different from the 120-second condition. Therefore, the 60-second condition could be used interchangeably with the 120-second condition in a clinical setting.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 4","pages":"62-69"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fb/70/dnd-20-62.PMC8585531.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39637467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the Potential Benefit of Shunt Surgery in Idiopathic Normal-Pressure Hydrocephalus Patients with Alzheimer's Disease Pathology. 关于特发性常压脑积水合并阿尔茨海默病病理的分流手术的潜在益处。

Dementia and neurocognitive disorders Pub Date : 2021-10-01 Epub Date: 2021-09-07 DOI: 10.12779/dnd.2021.20.4.108

Kyunghun Kang, Ki-Su Park, Sang-Woo Lee, Ho-Won Lee, Myong Hun Hahm, Chi-Hun Kim, Uicheul Yoon, Shin Young Jeong

{"title":"On the Potential Benefit of Shunt Surgery in Idiopathic Normal-Pressure Hydrocephalus Patients with Alzheimer's Disease Pathology.","authors":"Kyunghun Kang, Ki-Su Park, Sang-Woo Lee, Ho-Won Lee, Myong Hun Hahm, Chi-Hun Kim, Uicheul Yoon, Shin Young Jeong","doi":"10.12779/dnd.2021.20.4.108","DOIUrl":"https://doi.org/10.12779/dnd.2021.20.4.108","url":null,"abstract":"Many institutions rule out shunt surgery for idiopathic normal-pressure hydrocephalus (INPH) patients with Alzheimer's disease (AD) pathology. However, we believe some INPH patients with AD pathology might benefit from shunt surgery. While some reports suggest AD pathology may not adversely affect improvement after shunt surgery in INPH patients,1 the predominant position today is that AD pathology will adversely affect shunt surgery outcomes.2-4 For example, Hamilton et al.3 reported that INPH patients with moderate to severe AD pathology were associated with worse post-shunt outcomes. And Patel et al.4 reported INPH patients with high phosphorylated tau/amyloid beta 1-42 ratios showed less improvement following shunt surgery. Based on these studies, Jang et al.5 used amyloid positivity on positron emission tomography (PET) to exclude INPH patients for shunt surgery. However, the view that INPH patients with amyloid pathology should not have shunt surgery is likely based on older studies with less reliable methods and shorter follow-ups. We believe further studies are warranted to investigate whether some INPH patients with AD pathology can benefit from shunt surgery.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 4","pages":"108-111"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/20/dnd-20-108.PMC8585530.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39637941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Measurement of Subjective Cognitive Decline (SCD) Using Korean-Everyday Cognition (K-ECog) as a Screening Tool: a Feasibility Study. 韩国人日常认知(K-ECog)作为筛选工具测量主观认知衰退(SCD)的可行性研究

Dementia and neurocognitive disorders Pub Date : 2021-10-01 Epub Date: 2021-10-29 DOI: 10.12779/dnd.2021.20.4.80

Minji Song, Sun Hwa Lee, Seong Yoon Kim, Yeonwook Kang

{"title":"Measurement of Subjective Cognitive Decline (SCD) Using Korean-Everyday Cognition (K-ECog) as a Screening Tool: a Feasibility Study.","authors":"Minji Song, Sun Hwa Lee, Seong Yoon Kim, Yeonwook Kang","doi":"10.12779/dnd.2021.20.4.80","DOIUrl":"https://doi.org/10.12779/dnd.2021.20.4.80","url":null,"abstract":"Background and purpose: Everyday Cognition (ECog) has been widely used to differentiate individuals with mild cognitive impairment (MCI) and dementia from normal elderly individuals. It has also been used to assess subjective cognitive decline (SCD). This study investigated the feasibility of using ECog as a screening measure for SCD in community-dwelling elderly individuals.Methods: The participants included 84 older adults with and 93 without SCD living in the community. These 2 groups were classified based on their response (\"yes\" or \"no\") to the question \"Do you perceive memory or cognitive difficulties?\" All participants were evaluated using the Korean-Mini Mental State Examination (K-MMSE), Short form of the Geriatric Depression Scale (SGDS), and the Korean version of Everyday Cognition (K-ECog).Results: The scores of all participants were within the normal range on the K-MMSE and SGDS. The total K-MMSE score did not differ significantly between the 2 groups after controlling for age, education, and depression. The scores of SCD group were significantly higher than those of the non-SCD group for memory, language, and executive function: planning domains, as well as K-ECog total score. Receiver operating characteristic curve analysis revealed that the K-ECog total score was effective in moderately differentiating between subjects with and without SCD (area under the curve: 0.73).Conclusions: ECog is a feasible and useful screening measure for SCD in older adults living in the community, and can be used to assess the full spectrum of cognitive and functional deficits, ranging from SCD to MCI and dementia.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 4","pages":"80-88"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/35/dnd-20-80.PMC8585529.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39637469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Dementia and COVID-19 Mortality in South Korea. 韩国的痴呆症和COVID-19死亡率。

Dementia and neurocognitive disorders Pub Date : 2021-07-01 Epub Date: 2021-05-31 DOI: 10.12779/dnd.2021.20.3.38

Dae-Sung Kyoung, Jeongwoo Lee, Hyewon Nam, Moon Ho Park

引用次数: 5

Mortality Rates during Hospitalization and Affecting Factors in Geriatric Delirium Patients: a Retrospective Cohort Study. 老年谵妄患者住院期间死亡率及其影响因素:一项回顾性队列研究

Dementia and neurocognitive disorders Pub Date : 2021-07-01 Epub Date: 2021-06-16 DOI: 10.12779/dnd.2021.20.3.19

Selçuk Özdin, Recep Bolat

{"title":"Mortality Rates during Hospitalization and Affecting Factors in Geriatric Delirium Patients: a Retrospective Cohort Study.","authors":"Selçuk Özdin, Recep Bolat","doi":"10.12779/dnd.2021.20.3.19","DOIUrl":"https://doi.org/10.12779/dnd.2021.20.3.19","url":null,"abstract":"Background and purpose: The purpose of this study was to investigate the prevalence of mortality during hospitalization among patients diagnosed with delirium at geriatric consultations requested in the previous one year, together with the factors affecting this.Methods: The electronic medical records of geriatric consultations requested from the psychiatry department between January 1, 2019 and December 31, 2019 were examined from the automation system. The 200 geriatric delirium patients were included in the study. Patients' age, sex, length of hospital stay (LOHS), time between hospitalization and consultation, the department requesting consultation, reason for consultation request, psychiatric recommendations after consultation, reason for hospitalization, number of comorbid medical diseases, number of daily medications used, and history of psychiatric disease were retrieved from the electronic medical records in the automation system.Results: LOHS and time from hospitalization to consultation were longer in the exitus group. Numbers of comorbid disease and daily medications used were higher in the died patients. Male gender, higher numbers of comorbid diseases, and daily medications were predictors of death.Conclusions: Early detection of delirium may be important for short term results of disease. When evaluating these patients, reviewing the drugs used as much as possible can affect the outcome of the disease.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 3","pages":"19-27"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/51/dnd-20-19.PMC8326309.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39280694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Validity of the Montreal Cognitive Assessment (MoCA) Index Scores: a Comparison with the Cognitive Domain Scores of the Seoul Neuropsychological Screening Battery (SNSB). 蒙特利尔认知评估(MoCA)指数得分的效度:与首尔神经心理筛选组(SNSB)认知领域得分的比较。

Dementia and neurocognitive disorders Pub Date : 2021-07-01 Epub Date: 2021-07-27 DOI: 10.12779/dnd.2021.20.3.28

Haeyoon Kim, Kyung-Ho Yu, Byung-Chul Lee, Byeong-Chae Kim, Yeonwook Kang

{"title":"Validity of the Montreal Cognitive Assessment (MoCA) Index Scores: a Comparison with the Cognitive Domain Scores of the Seoul Neuropsychological Screening Battery (SNSB).","authors":"Haeyoon Kim, Kyung-Ho Yu, Byung-Chul Lee, Byeong-Chae Kim, Yeonwook Kang","doi":"10.12779/dnd.2021.20.3.28","DOIUrl":"https://doi.org/10.12779/dnd.2021.20.3.28","url":null,"abstract":"Background and Purpose A new approach was proposed to score the Montreal Cognitive Assessment (MoCA) index scores for 6 cognitive domains: orientation (OIS), attention (AIS), language (LIS), visuospatial function (VIS), memory (MIS), and executive function (EIS). This study investigated whether the MoCA index scores represent the functions of each cognitive domain by examining the correlations with the corresponding cognitive domain scores derived from conventional neuropsychological tests included in the Seoul Neuropsychological Screening Battery, 2nd Edition (SNSB-II). Methods The participants were 104 amnestic mild cognitive impairment (aMCI), 74 vascular mild cognitive impairment (VaMCI), 73 dementia of the Alzheimer's type (DAT), and 41 vascular dementia (VaD) patients. All participants were administered the Korean-MoCA and SNSB-II. Results Like the MoCA total score, the MoCA-OIS, MoCA-VIS, and MoCA-MIS showed differences between aMCI and AD groups and between VaMCI and VaD groups. The MoCA-AIS, MoCA-LIS, and MoCA-EIS showed significant differences between VaMCI and VaD groups, but no difference between aMCI and DAT groups. In the aMCI and VaMCI groups, all index scores of the MoCA showed significant correlations with the corresponding cognitive domain scores of the SNSB-II. Except for MoCA-MIS, the MoCA-AIS, MoCA-LIS, MoCA-VIS, and MoCA-EIS also showed significant correlations with the corresponding domain scores of the SNSB-II in the DAT and VaD groups. Conclusions These results indicate that all MoCA index scores, except for MoCA-MIS, which does not reflect the severity of memory impairment in dementia patients, provide highly valid information on the function of each cognitive domain in patients with mild cognitive impairment and dementia.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 3","pages":"28-37"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/8c/dnd-20-28.PMC8326308.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39280695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Coronavirus Disease 2019 and Dementia: The Survey for Dementia Patients in COVID-19 Crisis. 2019冠状病毒病与痴呆:对2019冠状病毒病危机中痴呆患者的调查

Dementia and neurocognitive disorders Pub Date : 2021-04-01 Epub Date: 2021-04-27 DOI: 10.12779/dnd.2021.20.2.16

Hojin Choi, Jae-Sung Lim, Chan-Nyoung Lee, Jae-Won Jang, SangHak Yi, Seunghee Na, Nayoung Ryoo, Kun Woo Park, Yong S Shim

{"title":"Coronavirus Disease 2019 and Dementia: The Survey for Dementia Patients in COVID-19 Crisis.","authors":"Hojin Choi, Jae-Sung Lim, Chan-Nyoung Lee, Jae-Won Jang, SangHak Yi, Seunghee Na, Nayoung Ryoo, Kun Woo Park, Yong S Shim","doi":"10.12779/dnd.2021.20.2.16","DOIUrl":"https://doi.org/10.12779/dnd.2021.20.2.16","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) crisis that began last year, has had a disruptive impact on our society.1 While the impact has affected society in general, it has affected certain groups of individuals disproportionately. Dementia patients are among the most vulnerable individuals in the society, and the COVID-19 crisis has further worsened their susceptibility. Notably, most of them are elderly patients who are vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19 complications.2,3 In order to prevent the spread of SARS-CoV-2 infection, most governments imposed mitigation measures including quarantine and movement restrictions. This confinement significantly limits physical, cognitive, and social activities and has consequently led to the rapid deteriorating of clinical symptoms in dementia patients.4 In addition, confinement is associated with several psychological effects, including depression, irritability, and anger, which are likely to have a negative impact on the already burdened caregivers both at home and nursing facilities. The Korean Dementia Association has been very concerned about the consequences of the pandemic on dementia patients and their families and has come up with two measures aimed at developing a strong support system; 1, developing care guidelines for dementia patients and caregivers, and 2, Conducting a survey to identify the extent of COVID-19 impact in dementia patients. The guidelines have already been published,5 herein, we report the findings of the survey.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 2","pages":"16-17"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/66/99/dnd-20-16.PMC8093012.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38976555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Multiple Enhanced Lesions in the Brain MRI of a Patient with COVID-19. 1例COVID-19患者脑MRI多发强化病灶

Dementia and neurocognitive disorders Pub Date : 2021-04-01 Epub Date: 2021-04-08 DOI: 10.12779/dnd.2021.20.2.13

Yu Min Kang, Noh Hyuck Park, Min Jae Seong, Hyun Jeong Han, Young Hee Jung

{"title":"Multiple Enhanced Lesions in the Brain MRI of a Patient with COVID-19.","authors":"Yu Min Kang, Noh Hyuck Park, Min Jae Seong, Hyun Jeong Han, Young Hee Jung","doi":"10.12779/dnd.2021.20.2.13","DOIUrl":"https://doi.org/10.12779/dnd.2021.20.2.13","url":null,"abstract":"A 67-year-old-male was hospitalised for COVID-19-associated-pneumonia on April 2, 2020. His first symptoms consisted of myalgia and a cough. COVID-19 was diagnosed based on the detection of SARS-CoV-2 viral nucleic acid through a nasopharyngeal swab specimen using real-time polymerase-chain-reaction assay. Chest computerised tomography showed patchy areas of consolidation in the peribronchial and subpleural areas of both lungs, which was consistent with COVID-19-associated-pneumonia. He had diabetes, chronic kidney disease without dialysis, and alcoholic liver disease. The patient was not a smoker, but a heavy drinker. Lopinavir/ritonavir and antibiotic therapy were initiated. On the 5th day of illness, the patient was intubated due to desaturation. On the 14th day, multi-organ failure was diagnosed, and continuous-renal-replacement-therapy and extracorporeal-membraneoxygenation were administered. On the 25th day, he was released from quarantine due to the negative results of three consecutive COVID-19-tests. He had stupor, but diffusion, and MRI showed no abnormal findings. The response was not improved until 42nd day, although sedative was not used.","PeriodicalId":72779,"journal":{"name":"Dementia and neurocognitive disorders","volume":"20 2","pages":"13-15"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/0b/dnd-20-13.PMC8093011.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38976554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0