Continence (Amsterdam, Netherlands)最新文献

{"title":"Increased prevalence of type 2 diabetes mellitus in urologic chronic pelvic pain syndrome","authors":"Benjamin E. Rubin ,&nbsp;Jacob I. Bleau ,&nbsp;Curtis A. Plante ,&nbsp;Craig V. Comiter","doi":"10.1016/j.cont.2025.102281","DOIUrl":"10.1016/j.cont.2025.102281","url":null,"abstract":"<div><h3>Background and objective</h3><div>Urologic chronic pelvic pain syndrome (UCPPS) includes interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). These conditions, hypothesized to be inflammatory in nature, are characterized by pelvic pain and urinary symptoms. Recent research has identified a higher prevalence of type 2 diabetes mellitus (T2DM) in females with IC/BPS; however, this association remains underexplored in males with CP/CPPS.</div></div><div><h3>Methods</h3><div>We conducted an observational study using the TriNetX database from 2004 to 2024. Males and females (≥18 years) were categorized into cohorts based on IC/BPS or CP/CPPS diagnoses. Each cohort was compared to a control group using propensity score matching based on age and BMI. Odds ratios (ORs) with 95 % confidence intervals were calculated for T2DM prevalence.</div></div><div><h3>Key findings and limitations</h3><div>T2DM was more prevalent in patients with UCPPS than in controls. Among IC/BPS patients, the OR for T2DM was 2.27 in males and 1.54 in females. In males with CP/CPPS, the OR was 1.75. All associations were statistically significant (p &lt; 0.0001). The use of ICD-10 codes introduces the potential for misclassification and missing data. Additionally, the severity of UCPPS cannot be captured using only ICD-10 codes.</div></div><div><h3>Conclusions</h3><div>Our findings demonstrate a significant association between UCPPS and T2DM, particularly in males with IC/BPS and CP/CPPS. The increased T2DM prevalence in IC/BPS aligns with prior studies. These results suggest shared inflammatory or metabolic pathways and support consideration of T2DM screening in this population. Further research is warranted to elucidate underlying mechanisms linking chronic pelvic pain and T2DM.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"16 ","pages":"Article 102281"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144913527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive symptoms as mediator between adverse childhood events and fecal incontinence and constipation in community-dwelling men and women","authors":"Dina M. Mahjoob ,&nbsp;Gommert A. van Koeveringe ,&nbsp;Marco H. Blanker ,&nbsp;Grietje E. Knol‐de Vries","doi":"10.1016/j.cont.2025.102287","DOIUrl":"10.1016/j.cont.2025.102287","url":null,"abstract":"<div><h3>Background</h3><div>Fecal incontinence (FI) and constipation affect quality of life and are influenced by intricate interactions between psychological and physiological factors. This study explores the association between adverse childhood events (ACEs) and adult bowel dysfunction (FI and constipation) in community-dwelling men and women, examining depressive symptoms as a potential mediator.</div></div><div><h3>Method</h3><div>A secondary analysis was conducted using baseline data from a population-based cohort (n = 1,691, age ≥16 years). Participants completed validated questionnaires on FI, constipation, history of emotional neglect, psychological, physical, sexual abuse, and depressive symptoms. Regression models were used, for men and women separately, to examine the associations between ACEs, FI, and constipation, and to test for mediation via depressive symptoms. Analyses were adjusted for age, body mass index, and smoking status.</div></div><div><h3>Result</h3><div>Complete data were available for 553 men and 787 women. Depressive symptoms significantly mediated the relationship between ACEs and both FI and constipation. For FI, ACEs had a small direct effect (β = 0.104, p &lt; 0.001) and a small, mediated effect (β = 0.057, p &lt; 0.001, Sobel test: z = 6.47). For constipation, ACEs showed a moderate direct effect (β = 0.171, p &lt; 0.001) and a moderate mediated effect (β = 0.130, p &lt; 0.001, Sobel test: z = 10.84).</div></div><div><h3>Conclusion</h3><div>Depression mediates the relationship between ACEs and bowel dysfunction, with a stronger role in constipation (moderate effect) compared to FI (small effect). These findings underscore the importance of addressing psychological factors and childhood adversity in understanding bowel dysfunction and informing clinical approaches.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"16 ","pages":"Article 102287"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short- and long-term outcome of sphincteroplasty for anal incontinence: Results from the Norwegian Registry of Anal Incontinence","authors":"Anna E. Kohler ,&nbsp;Tone Prosch-Bilden ,&nbsp;Stig Norderval","doi":"10.1016/j.cont.2025.102298","DOIUrl":"10.1016/j.cont.2025.102298","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to assess outcome after 1 and 5 years in patients who had undergone sphincteroplasty for anal incontinence (AI) in Norway.</div></div><div><h3>Methods</h3><div>The study was conducted as a retrospective cohort study based on prospectively recorded data from the Norwegian Registry of Anal Incontinence. AI was quantified using the St. Mark's score. Quality of life (QoL) was assessed with a simple visual analog scale with range 0–10. Primary endpoints were reduction in St. Mark's score and QoL score at follow-up.</div></div><div><h3>Results</h3><div>Some 75 patients had available results at year 1 follow-up, and 34 patients at year 5. Between baseline and year 1 there was a mean decrease in St. Mark's score of 3.9 points (p &lt; 0.001) and an increase in QoL-score of 0.4 points (p = 0.282). Between year 1 and year 5 mean St. Mark's score increased by 1.0 points (p = 0.359), while the QoL decreased by 1.7 points (p = 0.020). Comparing baseline with year 5, there was still a mean decrease in the St. Mark's score (p &lt; 0.001). A low St. Mark's score at baseline was statistically significantly associated with less reduction in St. Mark's score at year 1 (p &lt; 0.001), and patients with a baseline St. Mark's score of 9 or less experienced a mean St Mark's score increase of 0.25 point (p = 0.901). Neither age, menopause or ultrasonographic extent of sphincter defect prior to surgery affected outcome.</div></div><div><h3>Conclusion</h3><div>Patients with a baseline St. Mark's score of 9 or less have little to no benefit from sphincteroplasty for AI.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"16 ","pages":"Article 102298"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145465359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autonomic dysreflexia during urodynamics: A systematic review of incidence and predictors","authors":"Yash Khanna ,&nbsp;Tran Ngoc An Huynh ,&nbsp;Paul Manohar","doi":"10.1016/j.cont.2025.102288","DOIUrl":"10.1016/j.cont.2025.102288","url":null,"abstract":"<div><h3>Objectives</h3><div>Urodynamic investigation is a mainstay in assessment of lower urinary tract dysfunction in spinal cord injury (SCI). However, like with many forms of urological intervention in the SCI cohort – it carries a risk of autonomic dysreflexia (AD). This systematic review aims to ascertain the incidence and predictors of autonomic dysreflexia during urodynamic investigation, in those with SCI.</div></div><div><h3>Methods</h3><div>Systematic review was conducted according to PRISMA guidelines, and prospectively registered on PROSPERO (ID CRD420251000507). Ovid MEDLINE, Embase, Web of Science Core Collection and CINAHL databases were searched.</div></div><div><h3>Results</h3><div>Of total 2098 articles screened, 21 were ultimately included for systematic review. Of the 21 included studies, 13 reported incidence of AD during urodynamics, with reported incidence varyingly broadly from 7.9 to 90.9 %. In studies reporting SCI above T6 specifically, incidence of AD during urodynamics varied from 42.5 to 83.7 %, while in studies reporting incidence in SCI below T6, incidence varied from 5.9 to 82.3 %. There was heterogeneity in results regarding predictors of AD during urodynamics: level of injury was generally predictive of AD incidence, completeness of injury and patient age did not predict AD incidence but did potentially predict severity, and data regarding urodynamic predictors (detrusor overactivity, detrusor-sphincter dyssynergia, compliance, detrusor pressures) was conflicting. Several studies had high proportion of silent/asymptomatic AD (38–63 %), hence some authors suggested continuous/beat-to-beat cardiac monitoring during urodynamics in SCI patients to allow early identification and intervention for AD.</div></div><div><h3>Conclusion</h3><div>This systematic review identified the incidence of AD during urodynamics in SCI to be high, although results regarding predictors of AD were variable. Clinicians should consider continuous cardiac monitoring during urodynamics in at-risk SCI patients, and remain vigilant to risk of AD in SCI below T6. Future studies should aim to adopt a universal definition of AD and be prospective, to permit statistical synthesis and meta-analysis to conclusively define predictors of AD during urodynamics.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"16 ","pages":"Article 102288"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endogenous Vasopressin and Vasopressin Receptor 2 in Bladder as Anti-diuretic / Anti-spasmodic Targets for the Treatment of Multifactorial Nocturia","authors":"Irina Zabbarova ,&nbsp;Pradeep Tyagi ,&nbsp;Youko Ikeda ,&nbsp;Xiangyu Yan ,&nbsp;Visishta Ginjupally ,&nbsp;Sophia Percy ,&nbsp;Amanda Wolf-Johnson ,&nbsp;Shachi Tyagi ,&nbsp;Marcus Drake ,&nbsp;Karl-Erik Andersson ,&nbsp;Alan Wein ,&nbsp;Christopher Fry ,&nbsp;Anthony Kanai","doi":"10.1016/j.cont.2025.102292","DOIUrl":"10.1016/j.cont.2025.102292","url":null,"abstract":"<div><h3>Introduction</h3><div>Nocturia, the urge to wake from sleep to void, is targeted sub-optimally by existing drugs that modulate circadian dysregulation of urine production in kidney without alleviating detrusor overactivity, a key aspect in the multifactorial etiology of nocturia. This study reports age-related upregulation of arginine vasopressin (AVP) synthesis in mouse urinary bladder to counter the concurrent decline in the kidneys’ ability to concentrate urine, another prevalent symptom of nocturia.</div></div><div><h3>Methods</h3><div>Adult/aged C57Bl/6 mice of both sexes were anesthetized with isoflurane for bladder permeability experiments and used awake for cystometries with saline and soybean oil. Bladder overactivity was induced by chronic acrolein instillation. AVP and VR expression was examined by western blot and immunofluorescence.</div></div><div><h3>Results</h3><div>Aged mice showed lower urine osmolality relative to adults that coincided with upregulation of urothelial pre-pro AVP synthesis and VR2 expression that would complement the endocrine action of AVP in promoting bladder reabsorption of free water from stored urine. This was evident from the amplified systemic uptake of tritiated water following bladder instillation of AVP or vasopressin receptor 2 (VR2) agonist, desmopressin (dAVP). Fedovapagon, a small molecule VR2 agonist, exerted anti-diuretic action in kidney, surpassing the efficacy of AVP or dAVP in free water reabsorption from stored urine in bladder and dampened detrusor overactivity.</div></div><div><h3>Conclusion</h3><div>Fedovapagon, with its anti-diuretic actions on kidney, augments the therapeutic benefit activating VR2 receptors in urothelium to promote water reabsorption and relax the detrusor. Therefore, bladder VR2 activation by fedovapagon exemplifies a mechanistic paradigm for addressing the multifactorial etiology of nocturia.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"16 ","pages":"Article 102292"},"PeriodicalIF":1.2,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of urodynamic study in pudendal nerve entrapment syndrome","authors":"C. Fernandes ,&nbsp;V. Viegas ,&nbsp;A. Artiles Medina ,&nbsp;J. Morale Herrea ,&nbsp;J. Casado ,&nbsp;L. Vega ,&nbsp;C. Luque ,&nbsp;L. San José ,&nbsp;L. López-Fando Lavalle","doi":"10.1016/j.cont.2025.101917","DOIUrl":"10.1016/j.cont.2025.101917","url":null,"abstract":"<div><h3>Introductions and aims:</h3><div>Pudendal nerve entrapment is a rare cause of pelvic pain that can be associated with lower urinary tract symptoms (LUTS). The LUTS incidence among PNE patients and the urodynamic study (UDS) role are underexplored. This study aims to explore the role of the UDS in PNE diagnosis and describe the prevalence of LUTS in this population.</div></div><div><h3>Material and methods:</h3><div>This retrospective, multicentric, cross-sectional study analyzed 144 patients with suspected PNE syndrome between 2016 and 2024. Electronic medical urology records of chronic pelvic pain patients were evaluated. The diagnosis of PNE was established based on neurophysiological tests (NFS) and response to pudendal nerve block. Complaints of LUTS were recorded, and UDS was systematically performed as part of the diagnostic course. PNE patients with LUTS who underwent surgery were evaluated considering LUTS and pain improvement at 12 months postoperatively.</div></div><div><h3>Results:</h3><div>A total of 87 patients (60.4%) were diagnosed with PNE. Among them, 51% reported LUTS, with a similar prevalence in women (56%) and men (55%). A statistically significant difference was found between gender and UDS dysfunction (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>013</mn></mrow></math></span>), with underactive detrusor predominance in women (44%) and bladder outlet obstruction in men (40%). LUTS were more prevalent in patients with CPP from other causes, in both females (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>027</mn></mrow></math></span>) and males (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>030</mn></mrow></math></span>). UDS dysfunctions showed a statistically significant difference between PNE and other CPP causes only in females (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>023</mn></mrow></math></span>). Female PNE patients have more UDS anomalies in comparison to CPP from other causes. Of the PNE patients with LUTS, only 24 (60%) underwent surgery, and 11 (45.8%) experienced symptom improvement. In the univariate analysis, UDS results did not predict LUTS improvement after surgery (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>680</mn></mrow></math></span>).</div></div><div><h3>Conclusion:</h3><div><em>LUTS are highly prevalent in PNE and detectable in UDS. Assessing u</em>rinary symptoms is crucial in <em>PNE evaluation.</em> Urodynamic tests help clarify if LUTS stems from PNE or other CP causes. However, UDS findings do not predict LUTS improvement after surgery.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 101917"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144330557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lower Urinary Tract Dysfunction in Uncommon Neurological Diseases – Part IV: Infections, Inflammatory, Toxic, and Structural Disorders – A NUPC Report","authors":"Charalampos Konstantinidis ,&nbsp;Ryuji Sakakibara ,&nbsp;Desiree Vrijens ,&nbsp;Glenn T. Werneburg ,&nbsp;Blayne Welk ,&nbsp;Stephanie Kotes ,&nbsp;Marcus J. Drake ,&nbsp;Christina – Anastasia Rapidi ,&nbsp;Cristiano M. Gomes ,&nbsp;Luis Abranches-Monteiro ,&nbsp;Kadir Onem ,&nbsp;Stefan de Wachter ,&nbsp;Sanjay Sinha","doi":"10.1016/j.cont.2025.102274","DOIUrl":"10.1016/j.cont.2025.102274","url":null,"abstract":"<div><div>The manuscript examines the impact of various rare neurological disorders on lower urinary tract dysfunction (LUTD), building upon previous parts of this series. It discusses several infections and their sequelae, such as Neuroborreliosis (Lyme Disease), Herpes Zoster (HZ), and Neurosyphilis. Lyme Disease is a vector-borne infection leading to storage and voiding symptoms. Herpes Zoster (HZ) is associated with various types of LUTD due to its effect on spinal nerves. Neurosyphilis, historically, is a common cause of LUTD due to the degeneration of the spinal cord. In the manuscript, other miscellaneous conditions, such as Radiation Myelopathy, Decompression Sickness and Charcot Spine, are also discussed. Radiation Myelopathy is a chronic condition affecting bladder function post-radiation therapy. Decompression Sickness occurs in scuba divers and can lead to LUTD as a neurological complication. Charcot Spine represents a destructive spinal condition that can lead to LUTD and may require intensive management. Some degenerative disorders such as Progressive Multifocal Leucoencephalopathy (PML), Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), RSF1 related disorder – CANVAS (Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome), Acute Disseminated Encephalomyelitis (ADEM) and Spinal Cord Sarcoidosis which have varying impacts on LUT function are also included in this report. Additionally, the paper includes two metabolic and toxic myelopathies (severe B12 deficiency and Nitrous oxide myelopathy), which may cause LUTD.</div><div>The document emphasizes the necessity for urologists to recognize and manage LUTD in patients with these uncommon neurological conditions, promoting a comprehensive understanding of their overlaps in clinical symptoms. The overall goal is to better inform clinicians and aid in patient management by summarizing current knowledge and encouraging further research. This serves as the fourth installment in a series aiming to provide insights into rare neuro-urological diseases.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 102274"},"PeriodicalIF":1.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients’ experiences with self-management of conservative interventions for fecal incontinence","authors":"Donna Z. Bliss ,&nbsp;Marshall K. Muehlbauer ,&nbsp;Dominique Jamison ,&nbsp;Alexandra Weinberger ,&nbsp;Molly Conway ,&nbsp;Casey Kirchschlager ,&nbsp;Olga V. Gurvich ,&nbsp;Jeannine McCormick ,&nbsp;Ryanne Johnson ,&nbsp;Mary Benbenek ,&nbsp;Emma Jennings ,&nbsp;Joseph A. Konstan ,&nbsp;Holly E. Richter","doi":"10.1016/j.cont.2025.102273","DOIUrl":"10.1016/j.cont.2025.102273","url":null,"abstract":"<div><h3>Aims</h3><div>To describe patients’ experience self-managing conservative interventions for fecal incontinence (FI) during usual FI care.</div></div><div><h3>Methods</h3><div>Community-living adults with FI recruited from urogynecology and continence clinics participated in a pilot study developing a mobile application for FI self-management support. Data were collected using a demographics questionnaire, FI severity index tool, and semi-structured interviews about participants’ experience self-managing conservative interventions for FI which were part of their usual care treatment plan. Interviews were recorded and transcribed verbatim using online video software. Transcripts were analyzed using content analysis.</div></div><div><h3>Results</h3><div>Data from 17 women, aged 30 to ≥60 years, 9 White, 8 Black/African American, who had FI ranging from less than one year to more than 10 years were analyzed in this study. Themes of responses described starting interventions soon after receiving them, mixed opinions about ease of performing some interventions (e.g., pelvic floor muscle exercises, completing diaries), barriers to performing interventions (e.g., forgetfulness, no time), practical strategies facilitating self-management (e.g., setting alarms, keeping a schedule), emotional strategies that were supportive and motivating (e.g., maintaining hope, seeing positive results), and advice about self-management to others with FI (seek help, give it time).</div></div><div><h3>Conclusion</h3><div>Patient experiences provided clinicians with specific topics to target for patient education and ways to support themselves in self-managing FI.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 102273"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144680751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Group-based pelvic floor muscle training for urinary incontinence in Postmenopausal Women: Tips and tricks for successful practice: ICS 2023 workshop","authors":"Gabrielle Carrier-Noreau ,&nbsp;Mélanie Le Berre ,&nbsp;Joanie Mercier ,&nbsp;Sophie Mont-Briant ,&nbsp;Chantale Dumoulin","doi":"10.1016/j.cont.2025.101906","DOIUrl":"10.1016/j.cont.2025.101906","url":null,"abstract":"<div><div>Pelvic floor muscle training (PFMT) is the recommended first-line treatment for urinary incontinence and lower urinary tract symptoms. However, global availability of human and financial resources limits its accessibility. Group-based PFMT, which has been studied in postmenopausal women, offers a potential solution. This paper is based on the <em>Group-based intervention for pelvic floor muscle dysfunctions in postmenopausal women</em> workshop held during the 2023 International Continence Society Annual Scientific Meeting, in Toronto. It reviews the current evidence on group-based PFMT, discusses participant inclusion criteria, details the structure of the 12-week PFMT programme, presents remote group-based PFMT as an alternative to in-person group-based PFMT and proposes tips and tricks to empower clinicians in conducting Group-Based interventions for urinary incontinence and lower urinary tract symptoms.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 101906"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144694920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ketamine-induced uropathy","authors":"Hann-Chorng Kuo","doi":"10.1016/j.cont.2025.101907","DOIUrl":"10.1016/j.cont.2025.101907","url":null,"abstract":"<div><div>Ketamine induced uropathy has become a new bladder pain syndrome affecting the bladder, kidney, and quality of life in ketamine abusers. Ketamine-associated cystitis (KC) is an emerging public health concern, particularly among young adults who abuse ketamine recreationally and, to a lesser extent, in patients receiving ketamine therapeutically for depression. Although currently rare in clinical psychiatry, the incidence of KC might rise as ketamine-based therapies become more prevalent. This manuscript reviews recent knowledge in the ketamine induced uropathy and potential clinical implications.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 101907"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144178257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}