Continence (Amsterdam, Netherlands)最新文献

{"title":"Microbiome profiling in patients with Bladder Pain Syndrome/Interstitial cystitis","authors":"Puck Oude Elferink ,&nbsp;Aida Javan Balegh Marand ,&nbsp;John Heesakkers ,&nbsp;Ellen van den Munckhof ,&nbsp;Wilco Knetsch ,&nbsp;Frank Martens ,&nbsp;Mohammad Sajjad Rahnama’i ,&nbsp;Dick Janssen","doi":"10.1016/j.cont.2024.101743","DOIUrl":"10.1016/j.cont.2024.101743","url":null,"abstract":"<div><div>We conducted a microbiome study on BPS/IC patients with Hunner’s lesions to investigate the differences in local microbiome compositions within a single bladder. In addition, we compared BPS/IC urine samples with matched controls and overactive bladder (OAB) patients with or without detrusor overactivity. Furthermore, we performed a small pilot to evaluate the stability of the microbiome composition over time in a single BPS/IC patient.</div><div>Tissue samples were obtained from bladder mucosa from five adult female BPS/IC patients with confirmed Hunner’s lesions. From each patient one biopsy was taken from within the Hunner’s lesion area and one from outside the Hunner’s lesion area.</div><div>Urine samples from all five BPS/IC patients were compared to urine samples from normal age and sex matched controls (n <span><math><mo>=</mo></math></span> 12), female OAB patients with detrusor overactivity (n <span><math><mo>=</mo></math></span> 12) and female OAB patients without detrusor overactivity (n <span><math><mo>=</mo></math></span> 9). The 16S rRNA V1–V2 region amplification and gel electrophoresis were used to determine the microbiota.</div><div>Our results showed the small tissue size from a cold-cup mucosal biopsy yielded insufficient microbial DNA for 16S rRNA gene sequence analysis. Urine microbiome analyses demonstrated that there was no single bacterial genus that was specific for BPS/IC patients compared to the other groups. There was a wide variability in microbiome composition between the BPS/IC patients, but no significant difference was observed in the Shannon numerical analyses (microbiome diversity) in BPS/IC patients compared to controls. The small pilot that was done to evaluate microbiome stability over time in a single BPS/IC patient, showed remarkable stability of microbiome composition during a one-year follow-up.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"14 ","pages":"Article 101743"},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective, single-centre safety audit of the Altis® single incision sling in the surgical treatment of female stress urinary incontinence","authors":"E. Collier ,&nbsp;S. Housmans ,&nbsp;F. Van der Aa","doi":"10.1016/j.cont.2024.101741","DOIUrl":"10.1016/j.cont.2024.101741","url":null,"abstract":"<div><h3>Background:</h3><div>Single incision slings (SIS) and adjustable single incision slings (ASIS) are the latest generation of midurethral slings (MUS), used for the surgical treatment of female stress urinary incontinence, that seek to minimize the morbidity and complications associated to the conventional retropubic and transobturator midurethral slings. Its use has recently come under scrutiny following concerns about long-term complications.</div></div><div><h3>Aims:</h3><div>We conducted an internal audit of the short-to-medium term safety and absence of reported complications of the Altis® SIS in our medical centre (University Hospital of Leuven, Belgium). Secondary outcome was treatment efficacy, defined as no self-reported SUI symptoms.</div></div><div><h3>Methods:</h3><div>A file review of all patients implanted with an Altis® sling at our institution between 2014 and May 2021 was performed. Baseline characteristics and outcomes were reported with the use of descriptive statistics.</div></div><div><h3>Results:</h3><div>212 women were included in our safety analysis, 192 women in the efficacy analysis. The safety analysis showed 74 complications of any kind. Mesh exposure occurred in 16 women (7.5%) after a mean period of 15 months. Eleven of them (5.2%) underwent excision of the exposed mesh. Arterial haemorrhage requiring embolization, and mesh infection, both occurred once. Dyspareunia for the patient (3.3%) or her partner (1.4%) was encountered in nine cases. Four cases were linked to mesh exposure, of which three underwent partial sling excision. De novo urgency (5.7%) and urge incontinence (7.3%) were reported in 25 women (13%) and were managed with anticholinergic drugs. Regarding efficacy outcomes, 161 women (83.8%) reported no residual urine loss at the first post-operative consultation. Thirteen women (6.7%) had persistent SUI. Eight women (4.2%) underwent reintervention receiving a second sling.</div></div><div><h3>Conclusion:</h3><div>We can conclude that the short-to-medium term results in our centre align with those reported in existing literature.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101741"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing care for LUTS in older patients: Diagnostics, challenges of frailty and patient priorities—NOPIA meeting (ICI-RS 2024)","authors":"Andries Van Huele ,&nbsp;Michael Samarinas ,&nbsp;Wendy F. Bower ,&nbsp;Roger Dmochowski ,&nbsp;Dudley Robinson ,&nbsp;Mauro Van den Ende ,&nbsp;François Hervé ,&nbsp;William Gibson ,&nbsp;Adrian Wagg ,&nbsp;Alan Wein ,&nbsp;Karel Everaert ,&nbsp;George Bou Kheir","doi":"10.1016/j.cont.2024.101737","DOIUrl":"10.1016/j.cont.2024.101737","url":null,"abstract":"<div><div>As the global population ages, the prevalence of lower urinary tract symptoms (LUTS) in older adults is increasing, with frailty adding complexity to this challenge. There is a recognized paucity of data addressing LUTS in older adults with frailty.</div><div>This literature review, summarizing insights from a panel of experts at the 2024 NOPIA — Nocturia and Polyuria research group meeting at the International Consultation on Incontinence-Research Society (ICI-RS) congress in Bristol, addresses the need to optimize care for LUTS in older adults by refining diagnostics, adapting approaches for frail patients, considering patient priorities and identify indicators and predictors for LUTS.</div><div>The concept of lifelong LUTS underscores the persistence of urinary dysfunction across life stages, highlighting the importance of distinguishing age-related changes from pathology for accurate diagnosis. Due to age-related physiological changes, comorbidities, and cognitive decline, traditional diagnostics like frequency-volume charts may be challenging, emphasizing the value of a holistic, patient-centered approach. Treatments in frail populations require caution, as common medications can pose increased risks, often lacking safety data for this group, emphasizing the need for tailored approaches. Recognizing predictors and indicators of LUTS helps to prevent complications, understand progression and to aid in early intervention. Key patient priorities include effective symptom relief, low-risk management, and clear communication, with a strong preference for shared decision-making to accommodate individual needs, considering possible health illiteracy.</div><div>In conclusion, managing LUTS in older, frail adults requires a comprehensive approach that includes improving diagnostics, recognizing frailty’s impact, and aligning treatment with patient expectations. Future research should develop frailty-specific strategies to enhance quality of life, while a multidisciplinary, patient-centered approach can better address the complex needs of this population.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101737"},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survey of end user and health care professionals experience of discomfort as related to intermittent catheterisation","authors":"Angie Rantell ,&nbsp;Barbara Kearns ,&nbsp;Hanny Cobussen-Boekhorst ,&nbsp;Kay Willard ,&nbsp;Rene Zonderland","doi":"10.1016/j.cont.2024.101740","DOIUrl":"10.1016/j.cont.2024.101740","url":null,"abstract":"<div><h3>Background and Methods:</h3><div>Clinical evidence around discomfort experienced at the various stages of the intermittent catheterisation (IC) journey is limited. This research aimed to gain insights into discomforts encountered at initiation of IC and when products were changed/swapped during their lifetime of use. To gather a range of viewpoints, digital questionnaires were distributed to End Users and to Health Care Professionals (HCP’s) to consider how discomfort has/may be experienced and managed.</div></div><div><h3>Results:</h3><div>The surveys were completed by ninety nine End Users and 113 HCP’s. The results highlighted the variety of different ways in which discomfort may be described. For those End Users with urethral sensation, 89% stated the discomfort experienced acclimated i.e. they no longer felt the discomfort after a couple of days catheterising. Elements associated with improved experienced included End user education and how expectations were managed.</div></div><div><h3>Conclusions:</h3><div>The findings highlight the need to ensure that all End Users receive adequate education and counselling to manage all aspects of IC not only when they start their journey of IC, but also on product switching and during their lifetime of use and that this should be tailored to their individual needs. By having a better understanding in relation to discomfort it may help HCP’s to understand challenges faced, prepare End Users and set their expectations, and aid the development of more evidence-based education and training for IC users.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101740"},"PeriodicalIF":0.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there any association between socio-demographic characteristics and presenting complaints in patients with posterior compartment pelvic floor disorders?","authors":"Tanzeela Gala ,&nbsp;Abigail Fernandes ,&nbsp;Mehak Saini ,&nbsp;Carlotta Sarzo ,&nbsp;Noman Shahzad ,&nbsp;Carlene Igbedioh ,&nbsp;Alexis Schizas ,&nbsp;Alison Hainsworth ,&nbsp;Linda Ferrari","doi":"10.1016/j.cont.2024.101736","DOIUrl":"10.1016/j.cont.2024.101736","url":null,"abstract":"<div><h3>Introduction:</h3><div>Posterior compartmental pelvic floor disorders (PC-PFD) include symptoms of anal incontinence, obstructed defaecation (ODS) and functional anal pain <span><span>[1]</span></span>. According to the pelvic floor report in 2021, 6.5 million people suffered from bowel problems in the UK.</div><div>We determined the association of socio-demographic and clinical characteristics with presenting complaints in patients with PC-PFD and prevalence of the type of presenting complaint.</div></div><div><h3>Methods:</h3><div>This is a cross-sectional single-institution study of patients with (PC-PFD)reviewed in a tertiary pelvic floor unit between 2013 and 2019. Data was collected for socio-demographics from a prospectively maintained database and retrospectively for clinical factors.</div></div><div><h3>Results:</h3><div>Initial appointment was attended by 1956 patients with a mean age of 52.9 <span><math><mrow><mo>+</mo><mo>/</mo><mo>−</mo></mrow></math></span> 15.5 years. The. Main presenting complaints reported were obstructive defaecation (ODS – <span><math><mi>n</mi></math></span> = 819, 42.2%), anal incontinence (AI) (503, 25.9%), mixed (ODS and AI) (411, 21.2%), rectal prolapse (84, 4.3%), other complaints (rectal pain or bleeding – <span><math><mrow><mi>n</mi><mo>=</mo><mn>84</mn></mrow></math></span>, 4.3%) and symptoms of vaginal prolapse (38,2.1%).</div><div>ODS was associated with age &lt; 50 years, female gender and episiotomy while AI was associated with parity and prior hysterectomy and pelvic floor surgery. Rectal prolapse was associated with female gender while other complaints with age &lt; 50 years.</div></div><div><h3>Conclusion:</h3><div>This study reports socio-demographic and clinical risk factors associated with presenting complaints in patients with PC-PFD. This can form a basis for future prospective research to take initiatives for creating awareness about PC-PFD and identify symptoms in high-risk patients early to offer treatment or make timely referral from the community or primary care.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101736"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety and depression in colorectal Pelvic Floor Disorders among low Socioeconomic Status and ethnic groups","authors":"Aliki Rompou,&nbsp;Carlotta Sarzo,&nbsp;Abigail Fernandes,&nbsp;Fernando Safadi,&nbsp;Maxwell Renna,&nbsp;Alison Hainsworth,&nbsp;Linda Ferrari","doi":"10.1016/j.cont.2024.101734","DOIUrl":"10.1016/j.cont.2024.101734","url":null,"abstract":"<div><h3>Rationale:</h3><div>While anxiety and depression are noted in Pelvic Floor Disorders (PFD) patients, their influence on care and association with Socioeconomic Status (SES) and ethnicity are unstudied.</div></div><div><h3>Objective:</h3><div>To assess the impact of psychiatric conditions on PFD among ethnic minorities and different SES.</div></div><div><h3>Methods:</h3><div>A retrospective study conducted at Guy’s and St Thomas’ Hospital, London, UK. Patient demographics, main complaints, symptoms, psychiatric disorders, and data related to the entire care process were collected.</div><div>To assess the patients’ SES, we used the Index of Multiple Deprivation scores and grouped them into quintiles, with the lowest quintile representing the most deprived. Statistical tests evaluated how the care process differed between patients with and without psychiatric disorders, anxiety, or depression.</div></div><div><h3>Findings:</h3><div>Out of 2001 patients, 399 had at least one psychiatric disorder. These patients had higher rates of fecal​ incontinence (p = 0.02) and missed follow-up appointments more often (p = 0.005). No significant differences in clinical variables were found between patients with and without anxiety. Patients with depression had higher rates of anal incontinence (p = 0.005) and higher rates of referrals from the Telephone Assessment Triage Clinic to tests, diagnostic tests, and discussions in multidisciplinary meetings (p = 0.03, p = 0.04, p = 0.04). Furthermore, they were less likely to complete the care cycle (p = 0.02).</div></div><div><h3>Conclusions:</h3><div>This study highlights the impact of depression on patient care, underscoring the need to prioritize mental health for optimal treatment. No significant associations were found between psychiatric disorders and SES or ethnicity. Larger future studies are needed to explore potential correlations and develop targeted emotional support strategies.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101734"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urodynamic assessment of lower urinary tract function for women with symptoms of stress urinary incontinence. ICS Educational Module","authors":"Maurizio Serati ,&nbsp;Tufan Tarcan ,&nbsp;Anna Padoa ,&nbsp;Hashim Hashim ,&nbsp;Andrea Braga ,&nbsp;Karl Dietrich Sievert ,&nbsp;Peter F.W.M. Rosier","doi":"10.1016/j.cont.2024.101722","DOIUrl":"10.1016/j.cont.2024.101722","url":null,"abstract":"<div><h3>Aims:</h3><div>To present the body of evidence about the practice of objective assessment of lower urinary tract (LUT) function and dysfunction of female patients with stress urinary incontinence symptoms It serves as a scientific background review and evidence base for a presentation made available on the International Continence Society (ICS) website.</div></div><div><h3>Methods:</h3><div>This narrative review has been prepared by a working group instituted by the ICS Urodynamics Committee. The method to develop the educational module used included narrative literature review, consensus formation by the members of the Working Group, and review by members of the ICS Urodynamics Committee core panel.</div></div><div><h3>Results:</h3><div>On the basis of the available guidelines and articles, we addressed the following topics: Indications for comprehensive urodynamic study (UDS); the best way to inform and prepare the patient; the urodynamic study protocol in women with SUI; the practice of the different tests (cystometry with pressure flow study, leak point pressure and urethral pressure profile).</div></div><div><h3>Conclusions:</h3><div>This ICS teaching module includes an expert-based profile of patients with signs and symptoms of SUI that can be considered complicated and includes specific recommendations for the practice of testing. UDS helps diagnosing the dysfunction that leads to the symptoms. Most of the testing for women with stress urinary incontinence can be performed in the already standardized manner; some adaptions of practice and evaluation are mentioned.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101722"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of missed hospital appointments in patients with posterior compartment pelvic floor disorders in a tertiary referral centre","authors":"Tanzeela Gala ,&nbsp;Mehak Saini ,&nbsp;Abigail Fernandes ,&nbsp;Carlotta Sarzo ,&nbsp;Noman Shahzad ,&nbsp;Carlene Igbedioh ,&nbsp;Alexis Schizas ,&nbsp;Linda Ferrari ,&nbsp;Alison Hainsworth","doi":"10.1016/j.cont.2024.101729","DOIUrl":"10.1016/j.cont.2024.101729","url":null,"abstract":"<div><h3>Aim:</h3><div>Missed hospital appointments pose a major challenge to the healthcare system leading to worse patient outcomes. We ascertained the incidence of missed hospital appointments in patients with Posterior Compartment Pelvic Floor Disorders (PC-PFD) and associated socio-demographic and clinical predictors.</div></div><div><h3>Methods:</h3><div>This is a cross-sectional single-institution study from a tertiary pelvic floor unit (PFU) with data collected from a prospectively maintained database.</div><div>A missed appointment was marked if patients did not​ attend two consecutive appointments without informing or asking to re-schedule and were recorded for Telephone Triage Assessment Clinic (TTAC), Specialist-nurse, face-to-face bowel function clinic (BFC), Investigations including endoanal (EAUS) and pelvic floor ultrasound (PFUS) and defaecating proctogram (DP). All results yielding p&lt;0.05 were considered significant.</div></div><div><h3>Results:</h3><div>PFU received 2001 referrals between 2013 and 2019 with a mean age of 52 years. Missed appointments recorded were: TTAC — 45 (2.2%), BFC — 309 (15.8%), EAUS — 476(24%), PFUS — 484(37.2%) and DP — 432(26.2%).</div><div>Predictors determined were: Male gender, age &lt;50 years, complaints of rectal pain and bleeding for missing telephone and face-to-face appointments, low socioeconomic status for missing face-to-face appointments, and mixed and other ethnic groups with missing telephone appointments.</div></div><div><h3>Conclusion:</h3><div>This is the first study to report the incidence and socio-demographic and clinical predictors for missed appointments in patients with PC-PFD. Future prospective research, including qualitative studies interviewing patients, is needed to identify and address potential barriers patients face when accessing care for PC-PFD. This will help improve patient care and allow better utilisation of already constrained healthcare resources.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101729"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive therapies for older patients with urgency urinary incontinence: Current evidence and recommendations","authors":"Jacqueline Zillioux ,&nbsp;Amrita Ladwa ,&nbsp;Parker Holum ,&nbsp;Howard B. Goldman","doi":"10.1016/j.cont.2024.101733","DOIUrl":"10.1016/j.cont.2024.101733","url":null,"abstract":"<div><div>Overactive bladder (OAB) and urgency urinary incontinence (UUI) disproportionately affect older patients and overlap with multiple geriatric syndromes including frailty and cognitive impairment. Given concerns regarding polypharmacy and anticholinergic risks in older patients, there has recently been a push from multiple societies to eliminate the concept of “step therapy” and offer patients more individualized treatment options. This may involve offering minimally invasive therapies, traditionally referred to as “third line therapies”, without requiring trials of non-invasive or pharmacologic management. This narrative review considers current evidence and recommendations for minimally invasive therapies (onabotulinumtoxin A (BTX), sacral neuromodulation (SNM), percutaneous tibial nerve stimulation (PTNS), and implantable tibial nerve stimulation (ITNS)) in older and frail patients. There are no data to support one minimally invasive therapy over another. BTX and SNM may have slightly lower efficacy compared to younger patients, but the clinical relevance of this difference is unclear. BTX may have a higher risk of UTI and retention in older frail patients. While cognitive impairment alone should not preclude SNM, it is important to consider if planning for SNM. PTNS is the lowest risk option but carries a significant logistical burden that may reduce adherence. ITNS may mitigate this logistical burden; however, there are minimal data specific to this group and older frail patients may not be appropriate candidates. Ultimately, older patients with or without frailty should be considered candidates for minimally invasive therapies for OAB/UUI as available data support their safety and efficacy in these populations. However, there may be unique considerations for this group and treatment decisions should be individualized and based on shared decision making.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101733"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Fowler’s syndrome—Patient led phenotyping of 265 patients","authors":"Peter F.W.M. Rosier","doi":"10.1016/j.cont.2024.101730","DOIUrl":"10.1016/j.cont.2024.101730","url":null,"abstract":"","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"13 ","pages":"Article 101730"},"PeriodicalIF":0.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}