C. Fernandes , V. Viegas , A. Artiles Medina , J. Morale Herrea , J. Casado , L. Vega , C. Luque , L. San José , L. López-Fando Lavalle
{"title":"The role of urodynamic study in pudendal nerve entrapment syndrome","authors":"C. Fernandes , V. Viegas , A. Artiles Medina , J. Morale Herrea , J. Casado , L. Vega , C. Luque , L. San José , L. López-Fando Lavalle","doi":"10.1016/j.cont.2025.101917","DOIUrl":"10.1016/j.cont.2025.101917","url":null,"abstract":"<div><h3>Introductions and aims:</h3><div>Pudendal nerve entrapment is a rare cause of pelvic pain that can be associated with lower urinary tract symptoms (LUTS). The LUTS incidence among PNE patients and the urodynamic study (UDS) role are underexplored. This study aims to explore the role of the UDS in PNE diagnosis and describe the prevalence of LUTS in this population.</div></div><div><h3>Material and methods:</h3><div>This retrospective, multicentric, cross-sectional study analyzed 144 patients with suspected PNE syndrome between 2016 and 2024. Electronic medical urology records of chronic pelvic pain patients were evaluated. The diagnosis of PNE was established based on neurophysiological tests (NFS) and response to pudendal nerve block. Complaints of LUTS were recorded, and UDS was systematically performed as part of the diagnostic course. PNE patients with LUTS who underwent surgery were evaluated considering LUTS and pain improvement at 12 months postoperatively.</div></div><div><h3>Results:</h3><div>A total of 87 patients (60.4%) were diagnosed with PNE. Among them, 51% reported LUTS, with a similar prevalence in women (56%) and men (55%). A statistically significant difference was found between gender and UDS dysfunction (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>013</mn></mrow></math></span>), with underactive detrusor predominance in women (44%) and bladder outlet obstruction in men (40%). LUTS were more prevalent in patients with CPP from other causes, in both females (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>027</mn></mrow></math></span>) and males (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>030</mn></mrow></math></span>). UDS dysfunctions showed a statistically significant difference between PNE and other CPP causes only in females (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>023</mn></mrow></math></span>). Female PNE patients have more UDS anomalies in comparison to CPP from other causes. Of the PNE patients with LUTS, only 24 (60%) underwent surgery, and 11 (45.8%) experienced symptom improvement. In the univariate analysis, UDS results did not predict LUTS improvement after surgery (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>680</mn></mrow></math></span>).</div></div><div><h3>Conclusion:</h3><div><em>LUTS are highly prevalent in PNE and detectable in UDS. Assessing u</em>rinary symptoms is crucial in <em>PNE evaluation.</em> Urodynamic tests help clarify if LUTS stems from PNE or other CP causes. However, UDS findings do not predict LUTS improvement after surgery.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 101917"},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144330557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omer Anis , Mikolaj Przydacz , Tyler Trump , Saar Anis , Howard B. Goldman
{"title":"Global insights into overactive bladder management: A survey of physician preferences and practices","authors":"Omer Anis , Mikolaj Przydacz , Tyler Trump , Saar Anis , Howard B. Goldman","doi":"10.1016/j.cont.2025.101913","DOIUrl":"10.1016/j.cont.2025.101913","url":null,"abstract":"<div><h3>Introduction</h3><div>Overactive bladder syndrome (OAB) is a prevalent condition characterized by urinary urgency, frequency, and nocturia, significantly affecting quality of life. Despite advancements in treatment options, physician practices and preferences for managing OAB vary widely, especially between different specialties. This study aims to evaluate the current global trends, preferences, and barriers regarding the selection and use of available third-line therapies for OAB, with a focus on which treatments are most commonly available and preferred in clinical practice.</div></div><div><h3>Methods:</h3><div>This cross-sectional survey aimed to gather insights into physicians’ practices and opinions regarding OAB management. A 17-item questionnaire was developed and distributed electronically to members of the International Continence Society (ICS). The survey, conducted from April to July 2024, collected anonymous responses from 201 physicians. Data analysis included descriptive statistics, chi-square tests, and ANOVA using R software.</div></div><div><h3>Results:</h3><div>A total of 201 physicians responded, 60.7% of whom had completed fellowship training in relevant specialties. Among third line therapies, botulinum toxin injections and sacral neuromodulation (SNM) were the most favored treatments, with 46.2% and 29.9% of respondents rating them highly favorable, respectively. Urogynecologists from obstetrics and gynecology (OB-GYN) specialties were less likely to favor posterior tibial nerve stimulation (PTNS) compared to their urology-trained counterparts (p<0.001). Fellowship training significantly impacted the timing of follow-ups, with fellowship-trained physicians more likely to see patients at 4 weeks post-treatment. Key barriers to advanced therapies included patient resistance to implantable devices (65.8%) and limited neuromodulation training (27.9%).</div></div><div><h3>Conclusions:</h3><div>The management of OAB varies significantly across specialties, with notable differences in treatment preferences and barriers. While botulinum toxin and SNM remain popular choices, the availability of newer therapies such as implantable tibial nerve stimulation remains limited. Understanding these trends can inform future research and clinical guidelines aimed at improving OAB management and addressing barriers to advanced therapies.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 101913"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benjamin E. Rubin , Jacob I. Bleau , Curtis A. Plante , Craig V. Comiter
{"title":"Increased prevalence of primary bladder neck obstruction in conditions associated with hyperadrenergic signaling","authors":"Benjamin E. Rubin , Jacob I. Bleau , Curtis A. Plante , Craig V. Comiter","doi":"10.1016/j.cont.2025.101911","DOIUrl":"10.1016/j.cont.2025.101911","url":null,"abstract":"<div><div>Voiding dysfunction in primary bladder neck obstruction (PBNO) results from incomplete relaxation of the bladder neck, creating a functional obstruction. The efficacy of alpha-adrenergic antagonists supports the contention that adrenergic overactivity may contribute to increased bladder neck tone. This study examines the association between hyperadrenergic conditions and PBNO prevalence.</div><div>We conducted an observational study using the TriNetX database from 2004–2024. Males and females (<span><math><mo>≥</mo></math></span>18 years) were stratified into cohorts based on common disease states associated with hyperadrenergic signaling: anxiety, hypertension, obstructive sleep apnea, or heart failure. Each cohort was propensity score-matched to controls by age and BMI. Odds ratios (OR) with 95% confidence intervals (CIs) were calculated for PBNO prevalence, with statistical significance set at p < 0.01.</div><div>PBNO prevalence was significantly higher in all hyperadrenergic cohorts than in control groups without the diseases. Hypertension showed the strongest association, with ORs of 3.86 (males) and 4.96 (females). Anxiety also demonstrated substantial associations (ORs: 2.68 males, 3.14 females). All comparisons were statistically significant (p < 0.0001).</div><div>Our findings demonstrate a significant association between conditions characterized by increased adrenergic signaling and PBNO. The consistently higher ORs observed across all studied conditions, particularly hypertension and anxiety disorders, support the hypothesis that adrenergic overactivity may contribute to PBNO pathogenesis. These results suggest that patients with hyperadrenergic conditions may be at increased risk for PBNO and could benefit from targeted screening. Clinicians should consider the potential impact of these systemic conditions when evaluating and managing patients with lower urinary tract symptoms suggestive of PBNO.</div></div>","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"15 ","pages":"Article 101911"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144230450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eugenia Fragalà , Alberto Feruzzi , Valerio Vagnoni , Giulia Guidotti , Giovanni Sernaglia , Maria Grazia Conti , Samanta Fornia , Giacomo Saraceni , Rocco Francesco Delle Fave , Marco Guerra , Alexia Vici , Mara Bacchiani , Roberta Gunelli
{"title":"85 - Sharing a Best Practice for the use of intermittent catheterization in management of Urinary Retention due to benign prostatic hyperplasia","authors":"Eugenia Fragalà , Alberto Feruzzi , Valerio Vagnoni , Giulia Guidotti , Giovanni Sernaglia , Maria Grazia Conti , Samanta Fornia , Giacomo Saraceni , Rocco Francesco Delle Fave , Marco Guerra , Alexia Vici , Mara Bacchiani , Roberta Gunelli","doi":"10.1016/j.cont.2025.101851","DOIUrl":"10.1016/j.cont.2025.101851","url":null,"abstract":"","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"14 ","pages":"Article 101851"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damiano Graziani, Antonio Luigi Pastore, Antonio Carbone, Yazan Al Salhi, Andrea Fuschi, Paolo Pietro Suraci, Manfredi Bruno Sequi, Alice Antonioni, Onofrio Antonio Rera, Fabio Maria Valenzi, Giorgio Martino, Giuseppe Candita, Gianfrancesco Filippo, Paolo Benanti, Luca Erra, Giovanni Di Gregorio, Hila Rogozinski, Salvatore Viola, Gaia Vivarelli
{"title":"16 - Clean intermittent self catheterization in male patients with BOO and AUR might reintroduce spontaneous micturition: A prospective study","authors":"Damiano Graziani, Antonio Luigi Pastore, Antonio Carbone, Yazan Al Salhi, Andrea Fuschi, Paolo Pietro Suraci, Manfredi Bruno Sequi, Alice Antonioni, Onofrio Antonio Rera, Fabio Maria Valenzi, Giorgio Martino, Giuseppe Candita, Gianfrancesco Filippo, Paolo Benanti, Luca Erra, Giovanni Di Gregorio, Hila Rogozinski, Salvatore Viola, Gaia Vivarelli","doi":"10.1016/j.cont.2025.101783","DOIUrl":"10.1016/j.cont.2025.101783","url":null,"abstract":"","PeriodicalId":72702,"journal":{"name":"Continence (Amsterdam, Netherlands)","volume":"14 ","pages":"Article 101783"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}