Clinical nutrition research最新文献

{"title":"Development and Comparison of AI Algorithms for a Predictive Model of Cataracts: Analysis of the Korea National Health and Nutrition Examination Survey (2015-2017).","authors":"Jiyoung Choi, Eunju Park","doi":"10.7762/cnr.2025.14.4.297","DOIUrl":"10.7762/cnr.2025.14.4.297","url":null,"abstract":"<p><p>Cataracts are a major cause of visual impairment worldwide, particularly among older adults, with an increasing prevalence due to population aging. Surgery is the primary treatment; however, preventive strategies are crucial for reducing the disease burden. This study aimed to investigate dietary and health-related factors associated with cataract occurrence and develop a predictive model using machine learning. Data were derived from the Korea National Health and Nutrition Examination Survey 2015-2017. The study included 190 women aged 60-79 years: 124 with cataracts and 66 controls. Analyzed variables included sociodemographic, behavioral, chronic disease, and dietary intake factors. After data preprocessing, 4 machine learning algorithms: support vector machine (SVM), random forest (RF), eXtreme gradient boosting, and multilayer perceptron were used. Model performance was evaluated using accuracy, precision, recall, F1-score, and area under the receiver operating characteristic curve (AUROC) and precision-recall curves. Among the tested models, the SVM achieved the best performance under stratified 10-fold cross-validation, with 71% accuracy, 86% precision, 73% recall, 79% F1-score, 65% AUROC, and 81% AUPRC. According to our findings, the odds of having cataracts can be effectively predicted using dietary and health data without relying on specialized ophthalmic equipment. The proposed model demonstrates the potential of machine learning-based tools for early identification and prevention of cataracts. Future studies with larger and more diverse samples, as well as integrating additional data sources such as genomics and lifestyle factors, are warranted to refine predictive accuracy and enhance personalized nutrition-based interventions.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 4","pages":"297-307"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12629408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Muscle Quality and Quantitative Changes According to Nutritional Intake Differences in Patients Recovering From Trauma.","authors":"Ji-Hyun Lee, Songhee Kwon, Suyoung Yang, Donghwan Choi, Junsik Kwon, Yoo Kyoung Park","doi":"10.7762/cnr.2025.14.4.247","DOIUrl":"10.7762/cnr.2025.14.4.247","url":null,"abstract":"<p><p>Adequate nutrition reportedly can help reduce the degree of muscle loss and improve muscle quality in hospitalized patients recovering from trauma. This study investigated the association between nutritional intake and changes in muscle quality and quantity in these patients. The handgrip strength (HGS) and body composition of 52 patients admitted to the trauma ward were measured at 1-week intervals. According to their dietary intake, they were categorized into the hypocaloric nutrition group (HNG; < 70% of recommended caloric intake) and the isocaloric nutrition group (ING; ≥ 70% of recommended caloric intake). Within one week, body mass index (24.3 ± 4.4 kg/m² vs. 23.4 ± 4.5 kg/m²), body fat percentage (24.1% ± 9.8% vs. 17.2% ± 9.2%), and skeletal muscle mass (28.6 ± 4.9 kg vs. 27.5 ± 4.3 kg) significantly decreased in the ING compared with those in the HNG. Although the skeletal muscle mass decreased, the ING's left HGS significantly increased (26.6 ± 9.6 kg vs. 28.5 ± 10.1 kg). The ING also consumed a significantly greater amount of protein (beyond the recommended amount) than the HNG (72.6 ± 43.2 → 100.8 ± 27.0% vs. 58.6 ± 25.9 → 49.5 ± 20.1%; p = 0.039). In bioelectrical impedance vector analysis, the vectors of the ING shifted more within the normal range of the 75% tolerance ellipse than those of the HNG (23% vs. 10%). These results suggest that, although the muscle mass quantitatively decreased during trauma recovery, adequate nutritional support helps preserve muscle quality.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 4","pages":"247-259"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12629409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meal Patterns and Protein Food Utilization in Public and Private Geriatric Long-term Care Hospitals.","authors":"Ga-Eun Choi, Hye-Yeon Lee, Mi-Hyun Kim","doi":"10.7762/cnr.2025.14.4.260","DOIUrl":"10.7762/cnr.2025.14.4.260","url":null,"abstract":"<p><p>This study examined meal patterns and protein-rich food utilization in the foodservice practices of public and private geriatric long-term care hospitals in South Korea. Over a period of 6 months, a total of 612 daily menus (306 from each hospital type, breakfast, lunch, and dinner) were collected from four hospitals (two public, two private). Each menu was categorized by meal composition, included staple food, soup, main dish, side dishes, and kimchi. The most common meal pattern consisted of a staple food, soup, main dish, two side dishes, and kimchi. Compared with private hospitals, public hospitals offered a greater variety in meal composition, staple foods, soups, and main dishes. However, no significant differences were observed in protein foods of main dishes. Overall, meat accounted for about half, whereas fish accounted for one-third. Approximately 30% of protein foods in main dishes were processed. In side dish 1, the proportion of protein-rich foods was lower in public than in private hospitals, whereas the proportion of processed foods exceeded two-thirds in both hospital, but was significantly higher in public hospitals. Soup was the second most important protein source after the main dish, with fish as the most often used; however, processed protein foods were also common. These findings indicate that the main dish and soup are the principal protein sources, and the relatively high inclusion of fish reflects a favorable pattern. However, to ensure intake of high-quality proteins by older adults, the high reliance on processed protein foods highlights the need to reconsider foodservice practices.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 4","pages":"260-269"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12629413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Replacing Skipped Meals With Oral Nutritional Supplement on Nutritional Status and Physical Function in Older Adults.","authors":"Jiyeon Lee, Seong Ah Cho, Seoyoon Choi, Eunbi Han, Hyeri Shin, Yoo Kyoung Park","doi":"10.7762/cnr.2025.14.3.191","DOIUrl":"10.7762/cnr.2025.14.3.191","url":null,"abstract":"<p><p>This study evaluated the effects of replacing skipped meals with oral nutritional supplements (ONS) on the nutritional status and functional health of older adults. A total of 29 participants aged ≥ 65 years who regularly skipped at least one meal per day were included in this single-arm study. For 8 weeks, participants consumed two packs of ONS daily (150 mL each, providing 400 kcal and 18 g of protein) as a substitute for skipped meals. Nutritional status, nutrient intake, body composition, and physical function were assessed before and after the intervention. The Nutrition Quotient for the Elderly score significantly increased from 58.97 to 63.62 (p = 0.014). Total nutrient intake, including ONS, significantly improved compared with baseline (p < 0.01). Body weight and body mass index increased significantly from 58.87 to 59.47 kg (p = 0.028) and from 23.9 to 24.18 kg/m² (p = 0.016), respectively. Calf circumference decreased significantly from 34.1 to 33.39 cm (p = 0.010). Physical function, assessed using the Short Physical Performance Battery, showed significant improvement (p = 0.003). In conclusion, replacing skipped meals with ONS may enhance nutritional status and support functional health in older adults.</p><p><strong>Trial registration: </strong>Clinical Research Information Service Identifier: KCT0010184.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"191-203"},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macronutrient Intake and Cataract Incidence Among Koreans Aged 60 and Older: A Cross-Sectional Study Using 2015-2017 Korea National Health and Nutrition Examination Survey Data.","authors":"Jiyoung Choi, Eunju Park","doi":"10.7762/cnr.2025.14.3.204","DOIUrl":"10.7762/cnr.2025.14.3.204","url":null,"abstract":"<p><p>Cataracts are a major cause of vision impairment in older adults and pose a growing concern in aging societies. This study examined the association between dietary macronutrient intake and the odds of having cataracts among 1,619 Korean adults aged ≥ 60 years using data from the 2015-2017 Korea National Health and Nutrition Examination Survey. Cataracts were present in 51.8% of participants. Dietary intake was assessed via 24-hour recall and macronutrient intake was categorized by quartiles and energy ratios. After adjusting for covariates, individuals in the highest quartile of carbohydrate-to-energy intake (> 80%) had 41% higher odds of having cataracts (odds ratio [OR], 1.41; 95% confidence interval [CI], 0.99-2.01), with a significant trend (p for trend = 0.022). In contrast, the highest quartile of protein intake (Q3: 12%-15% energy) was associated with significantly lower odds of having cataracts in women (OR, 0.59; 95% CI, 0.40-0.88). Likewise, fat intake exceeding 18% of total energy was associated with reduced odds of having cataracts (OR, 0.69; 95% CI, 0.49-0.97). Saturated and monounsaturated fat intake also showed inverse associations with the odds of having cataracts. These results suggest that excessive carbohydrate intake, particularly when replacing fats and proteins, may increase the odds of having cataracts in older adults, especially among women. Dietary adjustments aimed at reducing the proportion of carbohydrates and increasing high-quality protein and fat intake may help prevent cataracts in aging populations. Further longitudinal studies are needed to clarify causal relationships and to inform nutritional guideline development.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"204-215"},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enteral Nutrition Management in a Patient With Traumatic Brain Injury in the Neuro-Intensive Care Unit: A Case Report.","authors":"Eunjin So, Yoon-Hee Choo","doi":"10.7762/cnr.2025.14.3.157","DOIUrl":"10.7762/cnr.2025.14.3.157","url":null,"abstract":"<p><p>Neurocritically ill patients often encounter challenges in maintaining adequate enteral nutrition (EN) owing to metabolic disturbances associated with increased intracranial pressure, trauma, seizures, and targeted temperature management. This case report highlights the critical role of the nutrition support team (NST) in overcoming these barriers and optimizing EN delivery in a patient with traumatic brain injury (TBI). A 59-year-old man was admitted to the neuro-intensive care unit following TBI. EN was initiated early in accordance with clinical guidelines. By the time of transfer to the general ward, 82.4% of the estimated energy requirement and 102.8% of the protein requirement were met. Despite this, the patient experienced 19.4% weight loss, likely due to underestimation of hypermetabolic demands and delays in EN advancement caused by fluctuating clinical conditions. NST adjusted the nutrition strategy by incorporating high-protein formulas, parenteral nutrition supplementation, and gastrointestinal management. This case report demonstrates the importance of individualized, multidisciplinary nutritional interventions in improving clinical outcomes for neurocritically ill patients.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"157-163"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of <i>Vaccinium meridionale</i> Swartz (agraz) Supplementation on Inflammatory and Oxidative Stress Markers in Patients With Metabolic Syndrome: A Systematic Review of Randomized Controlled Clinical Trials.","authors":"Zahra Moghaddas Mashhour, Hanieh Barghchi, Alireza Gheflati, Amir Hossein Mansouri, Zahra Dehnavi, Zahra Khorasnchi, Narjes Bahri Binabaj, Mohsen Sahebanmaleki, Jalil Moshari, Elyas Nattagh-Eshtivani","doi":"10.7762/cnr.2025.14.3.230","DOIUrl":"10.7762/cnr.2025.14.3.230","url":null,"abstract":"<p><p><i>Vaccinium meridionale</i> Swartz (commonly known as agraz or Andean blueberry is a wild fruit native to Colombia and rich in anthocyanins. In this systematic review, we evaluated the effects of agraz supplementation on inflammatory and oxidative stress markers in individuals with metabolic syndrome (MetS). A comprehensive literature search was conducted using PubMed, Scopus, ISI Web of Science, and Google Scholar for articles published up to March 2024, without restrictions on language, publication date, or geographical region. Among the 2,616 records identified initially through the database searches, 6 studies were included in this review. The risk of bias in the included studies was assessed using the Cochrane Collaboration's tool. Six randomized controlled trials (RCTs) involving 252 participants were analyzed. The intervention durations ranged from 21 days to 4 weeks, and the agraz supplementation doses were between 200 and 250 mL per day. Agraz supplementation significantly reduced urinary and serum levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG). However, among 3 studies examining high-sensitivity C-reactive protein (hs-CRP) levels, only 1 reported a statistically significant decrease in its levels. No significant effects were observed for other inflammatory or oxidative stress biomarkers. Agraz supplementation notable reduced urinary and serum 8-OHdG levels, suggesting potential antioxidant effects; however, its effect on hs-CRP levels remains inconclusive. No significant changes were observed in the levels of the other biomarkers. Further RCTs with larger doses and longer durations are necessary to confirm these findings and to clarify the therapeutic potential of agraz in MetS.</p><p><strong>Trial registration: </strong>PROSPERO Identifier: CRD42022369292.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"230-240"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Similarity in Diet Quality Between Children or Adolescents With Obesity and Their Mothers.","authors":"Hangsook Lee, Jieun Kim, Nayoung Kim, Hyung Gyu Park, Yoon Myung Kim, Kyung Hee Park, Hyunjung Lim","doi":"10.7762/cnr.2025.14.3.164","DOIUrl":"10.7762/cnr.2025.14.3.164","url":null,"abstract":"<p><p>Obesity is a multifactorial chronic disease influenced by behavioral, environmental, genetic, and psychological factors. One primary determinant of childhood obesity is the presence of dietary factors commonly acquired through the shared home food environment, which parents can greatly influence. Thus, the present study examined the similarity in diet quality between children or adolescents with obesity and their mothers. We analyzed baseline data collected from the Intervention for Children and Adolescent obesity via Activity and Nutrition study. Seventy mother-offspring dyads were identified, which included children and adolescents with obesity aged 8-16 years and their mothers living in Seoul and Gyeonggi Province, South Korea. Food or nutrient intake and diet quality were evaluated from 3-day food records. Childhood obesity was defined as body mass index ≥ 95th percentile based on the 2007 Korean National Growth Charts. No significant difference was observed in the diet quality score between children with obesity and their mothers. However, correlation coefficients between mothers and their children's total Diet Quality Index-International (DQI-I) score (r = 0.30) and subcategories, such as variety (r = 0.29), adequacy (r = 0.43), moderation (r = 0.45), and overall balance (r = 0.30), were positively correlated (p < 0.05). Linear regression analysis of the influence of maternal diet quality on offspring diet quality revealed that the maternal DQI-I score influenced the offspring's DQI-I score, consistent with our prediction. Further studies with larger and more representative samples are needed to confirm the applicability of our findings to all children and adolescent populations.</p><p><strong>Trial registration: </strong>Clinical Research Information Service Identifier: KCT0002718.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"164-173"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Dietary Intake and Its Association With Pulmonary Function and Chronic Obstructive Pulmonary Disease Risk in Korean Adults: 2016-2018 Korea National Health and Nutrition Examination Survey.","authors":"Seoyeon Park, Heejung Park","doi":"10.7762/cnr.2025.14.3.182","DOIUrl":"10.7762/cnr.2025.14.3.182","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is a major respiratory disorder characterized by irreversible airflow limitation. The role of diet in the prevention and management of COPD is receiving increasing attention. This study aimed to examine the association between the composite intake of vegetables, fruits, meat, and fish and pulmonary function as well as COPD prevalence in a representative sample of Korean adults aged ≥ 40 years using data from the 7th Korea National Health and Nutrition Examination Survey. Higher vegetable intake was associated with significantly better pulmonary function parameters, including forced vital capacity (p < 0.001), forced vital capacity percent predicted (p = 0.050), forced expiratory volume (FEV) in 1 second (FEV₁; p < 0.001), FEV₁ percent predicted (p = 0.038), FEV in 6 seconds (p < 0.001), and peak expiratory flow (p < 0.001). Furthermore, individuals with a high combined intake of vegetables, fruits, meat, and fish demonstrated a 0.261-fold lower COPD prevalence than those without such intake (p = 0.039). The dietary inflammatory index (DII) was significantly lower among participants without COPD than among those with COPD (mean DII = -3.6947, p = 0.002), indicating that a diet rich in anti-inflammatory nutrients can help reduce COPD risk. These findings suggest that vegetable consumption supports improved respiratory function, and a composite dietary pattern incorporating various food groups may help reduce the prevalence of COPD in the adult population.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"182-190"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions of Meat Alternatives Among Adolescents in Korea.","authors":"Bo-Young Lyum, Su-Ryeon Han, Minseo Choi, Mi-Kyeong Choi","doi":"10.7762/cnr.2025.14.3.174","DOIUrl":"10.7762/cnr.2025.14.3.174","url":null,"abstract":"<p><p>We investigated adolescents' perceptions of meat alternatives and examined the relationships among their views on various types of these alternatives. A survey was conducted with 372 middle and high school students, focusing on their perceptions of 3 categories of meat alternatives: plant-based meats, edible insects, and cultured meats. The relationships among these perceptions were subsequently analyzed. Overall, 77.4% of respondents were aware of meat alternatives, and 38.7% reported having consumed them. Perception levels differed by category, with plant-based meats receiving the highest scores, followed by cultured meats and edible insects. Notably, perceptions across the different categories of meat alternatives were significantly correlated. These findings suggest that increasing awareness about meat alternatives-particularly through education-may help promote sustainable and healthy eating behaviors among adolescents.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"174-181"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}