Clinical nutrition research最新文献_第4页

Positive Effects of Adiponectin, BDNF, and GLP-1 on Cortical Neurons Counteracting Palmitic Acid Induced Neurotoxicity. 脂肪连接素、BDNF 和 GLP-1 对皮层神经元的积极作用可抵消棕榈酸诱导的神经毒性

Clinical nutrition research Pub Date : 2024-04-26 eCollection Date: 2024-04-01 DOI: 10.7762/cnr.2024.13.2.121

Danbi Jo, Seo Yeon Ahn, Seo Yoon Choi, Yoonjoo Choi, Dong Hoon Lee, Juhyun Song

{"title":"Positive Effects of Adiponectin, BDNF, and GLP-1 on Cortical Neurons Counteracting Palmitic Acid Induced Neurotoxicity.","authors":"Danbi Jo, Seo Yeon Ahn, Seo Yoon Choi, Yoonjoo Choi, Dong Hoon Lee, Juhyun Song","doi":"10.7762/cnr.2024.13.2.121","DOIUrl":"10.7762/cnr.2024.13.2.121","url":null,"abstract":"The prevalence of metabolic syndrome caused by diets containing excessive fatty acids is increasing worldwide. Patients with metabolic syndrome exhibit abnormal lipid profiles, chronic inflammation, increased levels of saturated fatty acids, impaired insulin sensitivity, excessive fat accumulation, and neuropathological issues such as memory deficits. In particular, palmitic acid (PA) in saturated fatty acids aggravates inflammation, insulin resistance, impaired glucose tolerance, and synaptic failure. Recently, adiponectin, brain-derived neurotrophic factor (BDNF), and glucose-like peptide-1 (GLP-1) have been investigated to find therapeutic solutions for metabolic syndrome, with findings suggesting that they are involved in insulin sensitivity, enhanced lipid profiles, increased neuronal survival, and improved synaptic plasticity. We investigated the effects of adiponectin, BDNF, and GLP-1 on neurite outgrowth, length, and complexity in PA-treated primary cortical neurons using Sholl analysis. Our findings demonstrate the therapeutic potential of adiponectin, BDNF, and GLP-1 in enhancing synaptic plasticity within brains affected by metabolic imbalance. We underscore the need for additional research into the mechanisms by which adiponectin, BDNF, and GLP-1 influence neural complexity in brains with metabolic imbalances.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 2","pages":"121-129"},"PeriodicalIF":0.0,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Thickened Beverage and Swallowing Aid Jelly Used for Dysphagic Patients on the Disintegration of Orally Administered Tablets. 用于吞咽困难患者的增稠饮料和吞咽辅助果冻对口服片剂崩解的影响

Clinical nutrition research Pub Date : 2024-04-25 eCollection Date: 2024-04-01 DOI: 10.7762/cnr.2024.13.2.89

Won Hyeong Cho, Whachun Yoo, Byoungseung Yoo

{"title":"Effect of Thickened Beverage and Swallowing Aid Jelly Used for Dysphagic Patients on the Disintegration of Orally Administered Tablets.","authors":"Won Hyeong Cho, Whachun Yoo, Byoungseung Yoo","doi":"10.7762/cnr.2024.13.2.89","DOIUrl":"10.7762/cnr.2024.13.2.89","url":null,"abstract":"Thickened beverages or swallowing aid jelly (SAJ), commonly used as tablet-swallowing aids for dysphagic patients, may influence the disintegration of orally administered tablets. With this in mind, we evaluated the disintegration times of therapeutic tablets immersed in thickened beverages or SAJ compared to immersion in ones without them. Thickened beverages and SAJs were prepared with various beverages (water, orange juice, and milk) using food thickeners and SAJ powders marketed in Korea. The tablet disintegration times were the same in thickened beverages and SAJs, and there was no statistically significant difference associated with the thickness levels of the thickened beverages. The disintegration times of Tylenol immersed in orange juice or milk were slightly higher compared to those immersed in water. Moreover, there was no difference in disintegration time when using the thickened beverages and SAJs. The disintegration times of Aspirin were similar in all of the thickened beverages or SAJs, and there were no differences between non-immersed and immersed tablets. These results demonstrate that the disintegration of Tylenol and Aspirin is not greatly affected by immersion in any of the thickened beverages and SAJs.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 2","pages":"89-95"},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association of Body Mass Index on Falls Risk and Mortality in Hospitalized Patients of Different Old-Age Categories Requiring Nutritional Support. 身体质量指数与需要营养支持的不同老年住院患者的跌倒风险和死亡率的关系。

Clinical nutrition research Pub Date : 2024-04-25 eCollection Date: 2024-04-01 DOI: 10.7762/cnr.2024.13.2.96

Eunjung Kim, Eun-Mi Seol, Hyuk-Joon Lee

{"title":"The Association of Body Mass Index on Falls Risk and Mortality in Hospitalized Patients of Different Old-Age Categories Requiring Nutritional Support.","authors":"Eunjung Kim, Eun-Mi Seol, Hyuk-Joon Lee","doi":"10.7762/cnr.2024.13.2.96","DOIUrl":"10.7762/cnr.2024.13.2.96","url":null,"abstract":"Malnutrition affect clinical outcomes in hospitalized old age patients, but the data on the related outcomes on the basis of different age categories are still limited. We aimed to investigate the interplay of associations among body mass index (BMI), falls risk, and mortality rate in different older adult patient age categories. This retrospective study included hospitalized patients aged ≥ 65 years who received artificial nutrition. Demographic, biochemical, and survival data were collected. BMI was evaluated using the World Health Organization BMI cutoffs for Asians, and patients were classified into high (≥ 23.0 kg/m2), normal (18.5-22.9 kg/m2), and low (< 18.5 kg/m2) BMI groups. The Morse Fall Scale was used to assess falls risk. By age categories, all patients (n = 4,642) were divided into the 65-74 (n = 2,649) and ≥ 75 (n = 1,993) years age groups. We found that the proportion of low-BMI and high risk of falls increased with age. Further, low-BMI was associated with increased falls risk in both age groups. Overall survival rate tended to be lower in the low-BMI and ≥ 75 years group than that in other patient groups, but did not differ significantly compared with the low-BMI and 65-74 years group. Low-BMI was associated with increased falls risk and mortality; however, the association depended on specific patient age groups.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 2","pages":"96-107"},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Oral Chamomile on Anxiety: A Systematic Review of Clinical Trials. 口服甘菊对焦虑的影响：临床试验系统回顾

Clinical nutrition research Pub Date : 2024-04-23 eCollection Date: 2024-04-01 DOI: 10.7762/cnr.2024.13.2.139

Sogand Saadatmand, Foad Zohroudi, Hadith Tangestani

{"title":"The Effect of Oral Chamomile on Anxiety: A Systematic Review of Clinical Trials.","authors":"Sogand Saadatmand, Foad Zohroudi, Hadith Tangestani","doi":"10.7762/cnr.2024.13.2.139","DOIUrl":"10.7762/cnr.2024.13.2.139","url":null,"abstract":"Anxiety disorder is a prevalent psychiatric issue that affects 4.05% of the global population. As complementary and alternative medicine gains popularity, many individuals with anxiety symptoms seek herbal remedies. This systematic review aims to explore the sedative efficacy of chamomile as an herbal medicine for anxiety treatment. Our search was conducted in PubMed, Google Scholar, and Scopus databases until August 2023. Among 389 papers found, after removing duplicates and irrelevant papers, 10 clinical trials investigating the effect of oral consumption of chamomile on anxiety were included. Two researchers independently completed all steps, including the screening process and data extraction. Out of the 10 articles selected, 9 studies have concluded that chamomile is effective in reducing anxiety. Even though, the exact mechanism of chamomile's anxiolytic action is not well understood, evidence suggests that its active compounds, including apigenin, may modulate the function of the hypothalamic-pituitary-adrenocortical axis by affecting neurotransmitter pathways. This systematic review showed that chamomile potentially has an anxiolytic effect. In addition, due to the side effects of drugs used to treat anxiety disorders, the use of chamomile seems to be effective and less dangerous.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 2","pages":"139-147"},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association Between Food Quality Score (FQS) and Metabolic Syndrome Risk Factors in Overweight and Obese Individuals: A Cross-Sectional Study. 超重和肥胖者的食物质量得分（FQS）与代谢综合征风险因素之间的关系：一项横断面研究

Clinical nutrition research Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.7762/cnr.2024.13.1.51

Ali Hojati, Mahdieh Abbasalizad Farhangi

{"title":"The Association Between Food Quality Score (FQS) and Metabolic Syndrome Risk Factors in Overweight and Obese Individuals: A Cross-Sectional Study.","authors":"Ali Hojati, Mahdieh Abbasalizad Farhangi","doi":"10.7762/cnr.2024.13.1.51","DOIUrl":"10.7762/cnr.2024.13.1.51","url":null,"abstract":"Obesity and overweight pose a significant public health problem, as they are associated with an elevated risk of metabolic syndrome (MetS). Several studies have shown that diet quality is associated with the development of MetS risk factors. Analyzing dietary patterns may be more helpful in determining the relationship between eating habits and chronic diseases compared to focusing on single foods or nutrients. In this study, our objective was to evaluate the association of food quality score (FQS) with risk factors for MetS in individuals with obesity and overweight. The participants in this cross-sectional study were 340 adults with overweight and obesity. Participants' food intake was measured using a Food Frequency Questionnaire, then the FQS was calculated. A fasting blood sample assessed serum glucose, triglycerides, total cholesterol (TC), high-density lipoprotein cholesterol, and serum insulin levels. Fat-free mass, height, basal metabolic rate, socio-economic score, and waist-to-hip ratio significantly differed among FQS tertiles. TC, systolic and diastolic blood pressure, and fasting blood glucose were significantly lower in the highest tertile of FQS. After multivariable adjustment, our results showed that individuals in the third tertile of FQS had reduced risk of higher levels of TC (odds ratio [OR], 0.982; 95% confidence interval [CI], 0.970-0.984) and higher levels of low-density lipoprotein cholesterol (OR, 0.974; 95% CI, 0.974-0.999). Our findings demonstrate an inverse relationship between diet quality, as measured by FQS, and MetS risk factors. However, further experimental and longitudinal investigations are warranted to elucidate the causal nature of this association.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 1","pages":"51-60"},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between the Risk of Multiple Sclerosis and Dietary Proinflammatory/Anti-Inflammatory Food Intake and Dietary Diversity: A Case-Control Study. 多发性硬化症风险与膳食中促炎/抗炎食物摄入量和膳食多样性之间的关系：病例对照研究》。

Clinical nutrition research Pub Date : 2024-02-01 eCollection Date: 2024-01-01 DOI: 10.7762/cnr.2024.13.1.61

Alireza Hatami, Maryam Ahmadi-Khorram, Fatemeh Keykhaei, Ali Jafarzadeh Esfehani, Mohsen Nematy

{"title":"Association Between the Risk of Multiple Sclerosis and Dietary Proinflammatory/Anti-Inflammatory Food Intake and Dietary Diversity: A Case-Control Study.","authors":"Alireza Hatami, Maryam Ahmadi-Khorram, Fatemeh Keykhaei, Ali Jafarzadeh Esfehani, Mohsen Nematy","doi":"10.7762/cnr.2024.13.1.61","DOIUrl":"10.7762/cnr.2024.13.1.61","url":null,"abstract":"A diet rich in proinflammatory components and inflammation are suggested to be significant risk factors for multiple sclerosis (MS). This study aimed to investigate the association between the risk of MS and the inflammatory potential of an individual's diet and dietary diversity through pro-inflammatory/anti-inflammatory food intake score (PAIFIS) and dietary diversity score (DDS). In a hospital-based case-control study, 397 participants, including 197 patients with MS and 200 healthy participants aged over 18 years, were evaluated. The history of smoking, dietary intake, and anthropometric characteristics, including body mass index, waist circumference, total body fat, and fat-free mass were assessed. A validated 160-item semiquantitative food frequency questionnaire was used to calculate the PAIFIS and DDS scores. The mean age of the participants was 32.45 ± 8.66 years, and most were females (274, 79.4%). The PAIFIS score was significantly higher among MS patients than healthy participants (p = 0.001). Between PAIFIS and DDS, only PAFIS was significantly related to MS risk (odds ratio, 1.002; 95% confidence interval, 1.001-1.004; p = 0.001). PAIFIS, as an index of dietary inflammation, can predict MS. Further studies are needed to document these findings.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 1","pages":"61-73"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Dietary Fiber Intake and Low Muscle Strength Among Korean Adults. 韩国成年人膳食纤维摄入量与肌肉力量低下之间的关系

Clinical nutrition research Pub Date : 2024-01-31 eCollection Date: 2024-01-01 DOI: 10.7762/cnr.2024.13.1.33

Sunhye Shin

{"title":"Association Between Dietary Fiber Intake and Low Muscle Strength Among Korean Adults.","authors":"Sunhye Shin","doi":"10.7762/cnr.2024.13.1.33","DOIUrl":"10.7762/cnr.2024.13.1.33","url":null,"abstract":"The health benefits of dietary fiber are widely recognized, but its impact on muscle health remains unclear. Therefore, this study aimed to elucidate the relationship between dietary fiber intake and muscle strength through a cross-sectional analysis of data from the Korea National Health and Examination Survey (KNHANES). Data from a single 24-h dietary recall and handgrip strength tests of 10,883 younger adults aged 19 to 64 years and 3,961 older adults aged ≥ 65 years were analyzed. Low muscle strength was defined as handgrip strength < 28 kg for men and < 18 kg for women. Multivariable linear and logistic regression analyses were conducted to determine the association of dietary fiber intake with muscle strength. Approximately 43% of Korean adults met the recommended intake of dietary fiber, and those with higher dietary fiber consumption also had higher total energy and protein intake. After adjusting for confounding variables, dietary fiber intake was found to be positively associated with maximal handgrip strength in younger women aged 19 to 64 years (β = 0.015; standard error [SE] = 0.006) and older men aged ≥ 65 years (β = 0.035; SE = 0.014). For older women aged ≥ 65 years, those in the lowest quartile of dietary fiber intake had a higher risk of low muscle strength than those in the highest quartile after adjustment of confounders (odds ratio 1.709; 95% confidence interval 1.130-2.585). These results suggest that adequate dietary fiber intake may reduce the risk of sarcopenia in older Korean women.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 1","pages":"33-41"},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Health Status and Life Satisfaction According to Food Security in Single-Person Households of Elderly Population. 老年人单人家庭的健康状况和生活满意度与食品安全的比较。

Clinical nutrition research Pub Date : 2024-01-31 eCollection Date: 2024-01-01 DOI: 10.7762/cnr.2024.13.1.42

Dong Hoon Jung, Jae Won Han, Wonha Kim, Hee-Sook Lim

{"title":"Comparison of Health Status and Life Satisfaction According to Food Security in Single-Person Households of Elderly Population.","authors":"Dong Hoon Jung, Jae Won Han, Wonha Kim, Hee-Sook Lim","doi":"10.7762/cnr.2024.13.1.42","DOIUrl":"10.7762/cnr.2024.13.1.42","url":null,"abstract":"This study analyzed the 2019 Community Health Survey data to compare and analyze the health levels and life satisfaction of single-person elderly households based on food security. The final study subjects were 15,606 single-person elderly individuals aged 65 and above. These subjects were classified based on their response to food security into three groups: food sufficient-diverse, food sufficient-not diverse, and food insufficient. The study results showed that the proportion of the food insufficient group among single-person elderly households was 7.4% for men and 10.6% for women, with a slightly higher rate for female elderly. Both male and female elderly over 80 years of age, with low education levels, and basic living support recipients showed significantly higher proportions in the sufficient-not diverse and food insufficient groups. For male elderly, significant differences were observed in subjective health status and oral health level in the food insufficient group, and for female elderly, stress levels also showed significant differences. Life satisfaction scores were generally lower for female elderly compared to male, and significant differences were found in both male and female elderly based on food security. Common factors that significantly influence life satisfaction among single-person elderly households, both male and female, include food security, subjective health status, and living environment satisfaction, with food security being the most impactful factor. The study suggests that it is necessary to include these significant factors in the development of various social activity programs, such as dietary programs, to enhance life satisfaction and food security of single-person elderly households.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 1","pages":"42-50"},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Cinnamon Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 肉桂补充剂对血脂谱的影响：随机对照试验的系统回顾和元分析

Clinical nutrition research Pub Date : 2024-01-26 eCollection Date: 2024-01-01 DOI: 10.7762/cnr.2024.13.1.74

Hawal Lateef Fateh, Saman M Amin

{"title":"Effects of Cinnamon Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Hawal Lateef Fateh, Saman M Amin","doi":"10.7762/cnr.2024.13.1.74","DOIUrl":"10.7762/cnr.2024.13.1.74","url":null,"abstract":"Since the effects of cinnamon supplementation on lipid profiles are still controversial, this study conducted a meta-analysis of randomized controlled trials to assess the effect of cinnamon supplementation on lipid profiles. The study was designed and conducted according to the guidelines of the 2020 preferred reporting items for systematic reviews and meta-analysis (PRISMA) statements. A systematic and comprehensive search was performed in several databases from inception up to 11 November 2023. The meta-analysis on the impact of Cinnamon on lipid profiles indicates a non-significant overall effect on low-density lipoprotein (weighted mean differences [WMD], -2.48; 95% confidence interval [CI], -9.70, 4.72). However, significant reductions are seen with doses < 500 mg/day (-10.26), and non-significant increases with doses ≥ 500 mg/day (1.18). The overall effect on high-density lipoprotein is non-significant (WMD, 3.97; 95% CI, -7.877, 15.831), showing varying responses at different doses. Triglycerides exhibit a significant overall reduction (WMD, -6.88; 95% CI, -12.62, -1.15), particularly in the < 500 mg/day group. The overall effect on cholesterol is non-significant (WMD, -4.314; 95% CI, -15.011, 6.384), with diverse responses at different doses. High heterogeneity underlines the importance of standardized study designs and further exploration of dosage-specific effects. Findings from this study suggest that cinnamon supplements might be beneficial to modulate the blood lipid profile.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 1","pages":"74-87"},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enteral Nutrition in Critically Ill Patient With Septic Shock Requiring Vasopressor: Case Report. 需要使用血管加压素的脓毒性休克重症患者的肠内营养：病例报告。

Clinical nutrition research Pub Date : 2024-01-26 eCollection Date: 2024-01-01 DOI: 10.7762/cnr.2024.13.1.1

Hee Young Kim, Min Young Noh, Jisun Lee

{"title":"Enteral Nutrition in Critically Ill Patient With Septic Shock Requiring Vasopressor: Case Report.","authors":"Hee Young Kim, Min Young Noh, Jisun Lee","doi":"10.7762/cnr.2024.13.1.1","DOIUrl":"10.7762/cnr.2024.13.1.1","url":null,"abstract":"Nutritional support in critically ill patients is an essential aspect of treatment. In particular, the benefits of enteral nutrition (EN) are well recognized, and various guidelines recommend early EN within 48 hours in critically ill patients. However, there is still controversy regarding EN in critically ill patients with septic shock requiring vasopressors. Therefore, this case report aims to provide basic data for the safe and effective nutritional support in septic shock patients who require vasopressors. A 62-year-old male patient was admitted to the intensive care unit with a deep neck infection and mediastinitis that progressed to a septic condition. Mechanical ventilation was initiated after intubation due to progression of respiratory acidosis and deterioration of mental status, and severe hypotension required the initiation of norepinephrine. Due to hemodynamic instability, the patient was kept nil per os. Subsequently, trophic feeding was initiated at the time of norepinephrine dose tapering and was gradually increased to achieve 75% of the energy requirement through EN by the 7th day of enteral feeding initiation. Although there were signs of feeding intolerance during the increasing phase of EN, adjusting the rate of EN resolved the issue. This case report demonstrates the gradual progression and adherence to EN in septic shock patient requiring vasopressors, and the progression observed was relatively consistent with existing studies and guidelines. In the future, further case reports and continuous research will be deemed necessary for safe and effective nutritional support in critically ill patients with septic shock requiring vasopressors.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"13 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0