Actas espanolas de psiquiatria最新文献

{"title":"Reflections on the Potential and Risks of AI for Scientific Article Writing after the AI Endorsement by Some Scientific Publishers: Focusing on Scopus AI.","authors":"Jose De Leon, Santiago De Leon-Martinez, Antonio Artés-Rodríguez, Enrique Baca-García, Carlos De Las Cuevas","doi":"10.62641/aep.v53i2.1849","DOIUrl":"10.62641/aep.v53i2.1849","url":null,"abstract":"<p><p>The introduction of ChatGPT3 in 2023 disrupted the field of artificial intelligence (AI). ChatGPT uses large language models (LLMs) but has no access to copyrighted material including scientific articles and books. This review is limited by the lack of access to: (1) prior peer-reviewed articles and (2) proprietary information owned by the companies. Despite these limitations, the article reviews the use of LLMs in the publishing of scientific articles. The first use was plagiarism software. The second use by the American Psychological Association and Elsevier helped their journal editors to screen articles before their review. These two publishers have in common a large number of copyrighted journals and textbooks but, more importantly, a database of article abstracts. Elsevier is the largest of the five large publishing houses and the only one with a database of article abstracts developed to compete with the bibliometric experts of the Web of Science. The third use and most relevant, Scopus AI, was announced on 16 January 2024, by Elsevier; a version of ChatGPT-3.5 was trained using Elsevier copyrighted material written since 2013. Elsevier's description suggests to the authors that Scopus AI can write review articles or the introductions of original research articles with no human intervention. The editors of non-Elsevier journals not willing to approve the use of Scopus AI for writing scientific articles have a problem on their hands; they will need to trust that the authors who have submitted articles have not lied and have not used Scopus AI at all.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"433-442"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of 16S rRNA on Intestinal Flora Alterations and Early Diagnosis in Early Alzheimer's Disease Patients.","authors":"Danping Lv, Xiuqin Lin, Xinyuan Zhang, Qundi Shen","doi":"10.62641/aep.v53i2.1682","DOIUrl":"10.62641/aep.v53i2.1682","url":null,"abstract":"<p><strong>Background: </strong>Alzheimer's Disease (AD), a complex clinical condition, relies on neuropsychological assessments for early diagnosis. Recently, the gut-brain axis has been recognized as crucial in AD development, with dysbiosis in gut microbiota implicated in disease progression. Utilizing 16S rRNA analysis provides comprehensive monitoring of gut microbiota, potentially revealing biological markers for Early Alzheimer's Disease (EAD). Therefore, this study aimed to investigate the diagnostic impact of 16S ribosomal RNA (rRNA) on changes in intestinal flora among EAD patients.</p><p><strong>Methods: </strong>This study analyzed stool samples from 50 AD patients and 50 healthy controls between June 2022 and June 2023. Based on the disease stage, patients were categorized into EAD (n = 14) and Late Alzheimer's Disease (LAD) groups (n = 36). The V3-V4 region was sequenced using 16S rRNA quantitative Polymerase Chain Reaction (qPCR) to compare the composition of gut microbiota and differences in abundance among the three experimental groups.</p><p><strong>Results: </strong>The abundance and diversity of gut microbiota significantly increased in EAD patients compared to the healthy control group. Furthermore, 39 genera showed considerable variations between EAD and LAD patients and healthy controls, with notable increases in the abundance of Bryantella, Gemmiger, Desulfovibrio, Collinsella, and Odoribacter among EAD patients. Additionally, significant differences were observed across the Desulfovibrioales and Verrucomicrobiales, which could help distinguish EAD patients (Area Under the Curve (AUC) range 0.854, 0.966, p < 0.05).</p><p><strong>Conclusion: </strong>16S rRNA technology can be used to identify EAD patients, with the Desulfovibrioales and Verrucomicrobiales indicators serving as potential biological markers.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"208-221"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Age and Underlying Disease Characteristics in Patients with Mild to Moderate Depression Comorbid with Parkinson's Disease: A Retrospective Case-control Study.","authors":"Yiran Meng, Xiaoning Li, Wei Wang, Cixiang Dai, Wanchen Li, Junfei Li, Liyan Pan","doi":"10.62641/aep.v53i2.1702","DOIUrl":"10.62641/aep.v53i2.1702","url":null,"abstract":"<p><strong>Background: </strong>Depression is a widely recognized neuropsychiatric condition that often occurs as a comorbidity with various medical illnesses, including neurodegenerative disorders like Parkinson's disease (PD). This study aimed to identify the age of onset and underlying disease characteristics associated with patients exhibiting mild to moderate depression comorbid with PD.</p><p><strong>Methods: </strong>This retrospective case-control study included 114 elderly patients (age ≥65 years) diagnosed with Parkinson's disease. The patients were divided into two groups: the non-depressed group (n = 65) and the mild to moderate depression group (n = 49). Patients' emotional and affective symptoms, cognitive function, and clinical characteristics were assessed using standardized scales. Statistical analyses, including chi-square tests, Wilcoxon rank-sum tests, and logistic regression analysis, were performed to evaluate associations and correlations between the variables of interest.</p><p><strong>Results: </strong>Our findings revealed that patients in the mild to moderate depression group exhibited a significantly lower onset age of PD (52.33 ± 3.87 years) compared to the non-depressed group (59.27 ± 3.62 years, p < 0.001). Furthermore, patients with mild to moderate depression showed significantly higher scores in mood and affective symptoms measures, including the Hamilton Anxiety Scale (HAM-A) (p < 0.001) and Apathy Scale (p < 0.001). Additionally, the duration of Parkinson's disease was significantly longer in the mild to moderate depression group (6.78 ± 2.01 years) compared to the non-depressed group (3.45 ± 1.52 years, p < 0.001). Similarly, patients in the mild to moderate depression group exhibited significantly poorer performance on the Mini-Mental State Examination (MMSE) (p < 0.001), Montreal Cognitive Assessment (MoCA) (p = 0.025), verbal fluency (p < 0.001), and Trail Making Test (p = 0.005). Additionally, correlation and logistic regression analysis revealed associations and predictive value of these variables with the presence of mild to moderate depression in Parkinson's disease.</p><p><strong>Conclusion: </strong>The study highlights the complex interaction of age and underlying disease characteristics in patients with mild to moderate depression comorbid with Parkinson's disease. Early recognition and tailored management of depressive symptoms, mood and affective disturbances, cognitive impairment, and disease-specific characteristics are crucial for optimizing patient care and improving outcomes in individuals with Parkinson's disease. These findings underscore the need for a comprehensive, patient-centered approach that considers the diverse interaction of demographic, clinical, and cognitive variables.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"331-339"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Contributing to Sexual Dysfunction in Female Schizophrenia Patients During Recovery: A Multifactorial Analysis.","authors":"Jing Liu, Yina Zhang, Xu Mao","doi":"10.62641/aep.v53i2.1867","DOIUrl":"10.62641/aep.v53i2.1867","url":null,"abstract":"<p><strong>Background: </strong>Female patients with schizophrenia may experience sexual dysfunction during the recovery period. Therefore, this study conducted a multifactorial analysis to identify factors impacting sexual dysfunction, aiming to aid in developing effective personalized intervention strategies and improving sexual function recovery in these patients.</p><p><strong>Methods: </strong>This retrospective study included the clinical data from 261 female schizophrenia patients treated at the First Affiliated Hospital of Jinzhou Medical University, diagnosed between February 2022 and March 2024. Based on the total Female Sexual Function Index (FSFI) scores, the patients were divided into the female sexual dysfunction (FSD) group (n = 69) and the non-female sexual dysfunction (non-FSD) group (n = 192). The clinical data of these patients were evaluated using the FSFI, Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), and Olson Marital Quality Questionnaire. Furthermore, univariate and multivariate logistic regression analyses were used to investigate the factors influencing sexual dysfunction in these patients.</p><p><strong>Results: </strong>The FSD group exhibited significantly lower scores in sexual desire, orgasm, and sexual satisfaction than those in the non-FSD group (p < 0.001). Analysis revealed that menstrual status, reproductive history, and mental health status (anxiety and depression) were significantly associated with sexual dysfunction (p < 0.05). Furthermore, marital satisfaction, personality compatibility, spousal communication, conflict resolution methods, and sexual life were significantly linked to sexual dysfunction (p < 0.05). Additionally, childbirth (Odds Ratio (OR) = 2.531, 95% Confidence Interval (CI) = 1.025-6.25, p = 0.044), marital satisfaction (OR = 0.886, 95% CI = 0.824-0.952, p = 0.001), conflict resolution methods (OR = 0.816, 95% CI = 0.743-0.897, p < 0.001), sexual life (OR = 0.929, 95% CI = 0.876-0.986, p = 0.016), anxiety (OR = 1.459, 95% CI = 1.231-1.729, p < 0.001), and depression (OR = 1.116, 95% CI = 1.008-1.236, p = 0.035) were found as independent influencing factors for sexual dysfunction in these patients during the recovery phase.</p><p><strong>Conclusion: </strong>Childbirth, anxiety, depression, marital satisfaction, conflict resolution methods, and sexual life serve as independent influencing factors for sexual dysfunction in female schizophrenia patients during the recovery phase. Management approaches targeting these factors can significantly improve sexual dysfunction in this patient population.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"237-244"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Self-objectification and Adolescent Appearance Anxiety: A Mediated Model with Moderation.","authors":"He Zhang, Hongyu Li, Can Jiang, Yafeng Tu, Mengyao Xi","doi":"10.62641/aep.v53i2.1742","DOIUrl":"10.62641/aep.v53i2.1742","url":null,"abstract":"<p><strong>Background: </strong>The physical appearances of an individual are frequently scrutinized and evaluated by others in daily life. The rise of social media has intensified this scrutiny, leading to increased attention to and comparison of the appearance of an individual with others, leading to psychological challenges such as appearance anxiety. This study, from the perspective of self-objectification, explored the influence of self-objectification on appearance anxiety and the role of social appearance comparison and self-compassion in the relationship between self-objectification and appearance anxiety.</p><p><strong>Methods: </strong>A questionnaire survey was conducted among 842 adolescents using validated instruments, including the Self-objectification Scale, the Social Appearance Comparison Scale, the Self-compassion Scale, and the Appearance Anxiety Scale. Of these, 766 valid questionnaires were completed and analyzed.</p><p><strong>Results: </strong>(1) Self-objectification was a significant positive predictor of appearance anxiety. (2) Social appearance comparison partially mediated the relationship between self-objectification and appearance anxiety. (3) The second half of the mediation process in which self-objectification affects appearance anxiety through social appearance comparison was moderated by self-compassion.</p><p><strong>Conclusion: </strong>The effect of self-objectification on appearance anxiety is a mediated process with moderation.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"359-365"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the Correlation between Frailty Index, Clinical Characteristics, Use of Anti-Epileptic Drug, and Prognosis in Elderly Patients with Epilepsy.","authors":"Jianzhong Wang, Hengzhang Ma, Xiaodan Lin, Lixian Li, Zhixiong Zheng, Xiaohua Huang","doi":"10.62641/aep.v53i2.1729","DOIUrl":"10.62641/aep.v53i2.1729","url":null,"abstract":"<p><strong>Background: </strong>Epilepsy is a common neurological disorder among the elderly, often leading to significant morbidity. Therefore, it is necessary to study the correlation between the frailty index, clinical characteristics of epilepsy, use of anti-epileptic drug, and the prognosis of elderly patients with epilepsy.</p><p><strong>Methods: </strong>This retrospective study included 106 elderly patients with epilepsy who were treated at the Affiliated Mindong Hospital, Fujian Medical University, China, between January 2018 and December 2022. Based on the severity of the prognosis, the seizures were classified into the major seizure group (tonic-clonic), minor seizure group (absence, myoclonus, clonus, tonic, atonic and partial seizures), and no seizure group. Furthermore, the relationship between the frailty index, clinical characteristics, use of epilepsy drugs, and the degree of epileptic seizures was assessed using the Logistic regression analysis.</p><p><strong>Results: </strong>Univariate analysis indicated that older age (p < 0.001), longer disease duration (p = 0.009), and the presence of comorbid conditions such as diabetes (p = 0.002) and coronary heart disease (p < 0.001) were all associated with seizure severity. Additionally, frailty was significantly related to seizure severity, with the non-frailty group having fewer major seizures compared to the pre-frailty and frailty groups (p < 0.001). Similarly, regular medication use (p < 0.001) and the number of drugs taken (p < 0.001) were significant factors, with irregular medication use and single-drug regimens being more common in patients with more severe seizures. Multivariate Logistic regression analysis indicated that a higher frailty index (p = 0.033), age over 70 years (p = 0.015), longer disease duration (p = 0.003), the presence of coronary heart disease (p < 0.001), and regular medication use (p = 0.022) were all significantly associated with more severe seizures.</p><p><strong>Conclusion: </strong>Frailty index, age, disease duration, coronary heart disease, and regular medication are related to the prognosis of elderly patients with epilepsy. These findings highlight the significance of comprehensive management strategies to improve clinical outcomes in this group of patients.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"284-291"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stressful Life Events and Neuroticism among Chinese Women with Recurrent Major Depressive Disorder.","authors":"Fengfeng Chu, Chu Wang, Shufei Tao, Jingfang Gao, Xiangzhen Zhu, Danhong Tao, Bijun Chen, Ming Tao","doi":"10.62641/aep.v53i2.1730","DOIUrl":"10.62641/aep.v53i2.1730","url":null,"abstract":"<p><strong>Background: </strong>Depression is associated with a high incidence of stressful life events (SLEs) and neuroticism. However, the impact of SLEs and neuroticism on the recurrence of major depressive disorder (MDD) remains unclear. Therefore, we aimed to identify the potential causal relationship between SLEs, neuroticism, and depression recurrence.</p><p><strong>Methods: </strong>This study included 5561 female patients with recurrent MDD (ages 30-60) and 4257 healthy volunteers (ages 40-60) from the China, Oxford, and Virginia Commonwealth University Experimental Research on Genetic Epidemiology (CONVERGE) study. We compared the female patients with recurrent MDD to a gender and age-matched group of healthy volunteers. Odds ratios (ORs) were calculated using logistic regression analysis to assess the impact of SLEs on depression onset. Furthermore, we employed bootstrapping sampling procedures to explore the mediating role of neuroticism between SLEs and the number of depressive episodes.</p><p><strong>Results: </strong>SLEs contributed to the occurrence of major depression, with rape (OR = 19.14, p = 0.004), serious neglect (OR = 3.65, p < 0.001), legal problems (OR = 2.51, p < 0.001), and divorce or relationship breakup (OR = 2.14, p < 0.001) being significantly associated with the onset of MDD. Following MDD onset, certain SLEs, such as the death of a family member (Z = 3.64, p < 0.001), unemployment (Z = 5.63, p < 0.001), job termination (Z = 6.43, p < 0.001), and financial crisis (Z = 5.53, p < 0.001), led to a significant increase in the number of depressive episodes. Furthermore, mediation analysis demonstrated that events such as divorce or relationship breakup (p < 0.05), rape (p < 0.05), financial crisis (p < 0.05), and physical abuse (p < 0.05) indirectly affected the number of depressive episodes through neuroticism.</p><p><strong>Conclusions: </strong>Our study demonstrates that SLEs in different categories have different effects on the onset and recurrence of MDD, and their effects regarding personal maltreatment, interpersonal relationship, and finance on the recurrence of depression are mediated by neuroticism.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"348-358"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Behavioral Therapy Improves the Quality of Life for Patients with Mild to Moderate Depression due to Glaucoma or Cataracts: A Retrospective Study.","authors":"Yinchen Lin, Hong Zhang, Chunliu Shi, Na Yang, Xiaoqing Li, JinHua Gan","doi":"10.62641/aep.v53i2.1673","DOIUrl":"10.62641/aep.v53i2.1673","url":null,"abstract":"<p><strong>Background: </strong>Individuals affected with glaucoma and cataracts are more likely to experience depressive symptoms, which can affect their overall quality of life (QOL) and functioning. Therefore, this retrospective cohort study aimed to evaluate the impact of cognitive behavioral therapy (CBT) on glaucoma or cataracts patients with mild to moderate depression.</p><p><strong>Methods: </strong>This study included patients with mild to moderate depression resulting from glaucoma or cataracts in our hospital from January 2023 to December 2023. The study participants were divided into an untreated group and a cognitive behavioral therapy group based on different intervention methods. We assessed depressive symptoms using the Center for Epidemiologic Studies Depression Scale (CES-D) and Patient Health Questionnaire-9 (PHQ-9). QOL was evaluated using the Chinese translation version of the European Quality of Life-5 Dimensions scale (EQ-5D), Short Form Health Survey (SF-36), National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Additionally, cognitive behavioral therapy (CBT) was administered to a subgroup of patients with mild to moderate depression, and the impact of CBT on the well-being of the patients was analyzed.</p><p><strong>Results: </strong>This study included 3010 individuals, consisting of untreated patients (n = 2151) and those who received cognitive behavioral therapy (n = 859). Post-intervention analysis revealed that compared to baseline, the CES-D scores (p < 0.001), PHQ-9 scores (p < 0.001), and HADS anxiety subscale scores (p < 0.001) were significantly reduced in the CBT group. Furthermore, the CBT group demonstrated a significant increase in EQ-5D scores (p < 0.001) and SF-36 mental component scores (p < 0.001) post-intervention compared to baseline.</p><p><strong>Conclusion: </strong>These findings offer significant insights into the prospective effectiveness of CBT in improving depressive symptoms and QOL in individuals with glaucoma or cataracts.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"245-252"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Morita Therapy for Treating Hospitalized Patients with Depression.","authors":"Haiqun Shen, Yiyu Mao, Yu'e Fei, Yuchao Lu","doi":"10.62641/aep.v53i2.1714","DOIUrl":"10.62641/aep.v53i2.1714","url":null,"abstract":"<p><strong>Background: </strong>Depression is a common mental illness worldwide. Morita therapy is a novel and effective intervention method for treating depression patients. This study aimed to investigate the effects of modified Morita therapy on social functioning and quality of life in individuals suffering from depression.</p><p><strong>Methods: </strong>The data of depressive patients hospitalized in Kangci Hospital of Jiaxing from June 2021 to May 2022 were collected and analyzed by propensity score matching (PSM). The control group received antidepressant treatment and standard psychiatric care (n = 30), while the study group received modified Morita therapy on the basis of standard treatment (n = 30). Both experimental groups received a six-week intervention. The 17-item Hamilton Depression Scale (HAMD-17) was used to assess the severity of depression before and after the intervention. Hamilton Anxiety Scale (HAMA) was used to assess the anxiety level of patients. Social Dysfunction Screening Scale (SDSS) was used to evaluate the social functioning of the patients. Generic Quality of Life Inventory-74 (GQOLI-74) was implemented to evaluate the quality of life of patients based on four dimensions: physical function, psychological function, social function, and material life status through 74 items.</p><p><strong>Results: </strong>After six weeks of intervention, the study group exhibited significantly reduced HAMD-17, HAMA, and SDSS scores compared to the control group (p < 0.05). Furthermore, significant improvements were observed in physical function, psychological function, social function, material well-being domains, and the overall GQOLI-74 questionnaire scores within the study group compared to the control group (p < 0.05).</p><p><strong>Conclusion: </strong>Modified Morita therapy effectively alleviates depression and anxiety levels among depressed patients while enhancing their social functioning and improving their quality of life, thus highlighting its clinical applications.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"324-330"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptability of VloV, a Mobile App Developed in Latin America for People with Substance Use Disorder among an Intensive Outpatient Treatment.","authors":"Diana Milena Berrio Cuartas, Carola Cassinelli, Luciana Noemi Garcia, Federico Pavlovsky","doi":"10.62641/aep.v53i2.1701","DOIUrl":"10.62641/aep.v53i2.1701","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Digital therapeutic tools seem to be helpful for substance use disorders (SUD), but there are few studies in Latin America about this approach. Our group of therapists developed VloV (an abbreviation for Pavlovsky), a mobile app that attempts to digitize practical tools along with strengthening the therapeutic alliance and user practice.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Method: &lt;/strong&gt;We conducted a mixed-method pilot study between August 2021 and January 2022 to collect data about the patient experience using VloV and the therapeutic alliance among 23 patients. VloV is a Spanish mobile app available for free that focuses on SUD and covers therapeutic elements and tools from an intensive outpatient treatment program. A monthly PDF report containing the patient's daily interactions is generated and can be shared via e-mail with the therapist for follow-up. We run three questionnaires (Q), Q1 regarding technology use indications Q2 to review content information and the utility of the different elements of VloV, and Q3 to collect qualitative data about participants' experiences and perceptions. Several aspects of the therapeutic alliance were evaluated using the patient version of the Working Alliance Inventory in its short version (WAI-S-P). Several aspects of the therapeutic alliance were assessed using the patient version of the Working Alliance Inventory in its short version (WAI-S-P). The level of agreement between the raters-provider and monthly VloV reports-was calculated for treatment variables in patients and their mood state records. For some sub-analysis, patients were divided into two categories, those who have a daily app's use and those who have a weekly or sporadic use.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Patient characteristics were similar to the statistics of the treatment center data, including the dropout rate; only 15 out of 23 (65.2%) patients completed the 12 weeks of the pilot study. Participants reported daily use of the technology, but only 5.0% searched for health topic information on the web. Patients expressed positive feedback by using the app and found some functional aspects in VloV that contributed to their treatments and self-care as mood scale record, money earned display, sobriety calculator, and treatment skill functions. However, the \"red button\" function, which allows the patient to ask for help, was not found to be of much use. We found a correlation between the frequency app's use and a higher accuracy in the provider register of treatment related to variables. Although working alliance therapeutic scores were mainly high and non-differences were found.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This is the first study on a mobile application for SUD developed in our region, and although it is only a preliminary study, it pointed out important lessons about incorporating digital therapeutic tools into mental health treatment in an intensive outpatient treatments (IOT) setting.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical trial ","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"304-314"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}