Actas espanolas de psiquiatria最新文献

{"title":"Differential Effects of Morning Versus Afternoon Accelerated High-Frequency Repetitive Transcranial Magnetic Stimulation on Sleep Outcomes in Hospitalised Patients With Schizophrenia: Retrospective Cohort Study.","authors":"Yufeng Xiong, Yan Zhang, Haoshui Hua, Jixin Lin, Mengting Li, Qicheng Zhang, Linlin Jiang","doi":"10.62641/aep.v54i3.2227","DOIUrl":"10.62641/aep.v54i3.2227","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the differential effects of accelerated high-frequency repetitive transcranial magnetic stimulation (aHF-rTMS) administered in the morning and afternoon on sleep outcomes in hospitalised patients with schizophrenia.</p><p><strong>Methods: </strong>This single-centre retrospective cohort study was based on existing inpatient records from the Department of Psychiatry at The Third People's Hospital of Fuyang between November 2023 and May 2025. Eligible cases were identified from electronic medical records, nursing documentation and aHF-rTMS treatment logs. Patients were divided into a morning aHF-rTMS group and an afternoon aHF-rTMS group according to the predominant treatment-time category documented during hospitalisation. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), and nighttime sleep duration was obtained from nursing records. Psychiatric symptoms and cognitive function were assessed using the Positive and Negative Syndrome Scale (PANSS) and Montreal Cognitive Assessment (MoCA), respectively. The influencing factors of sleep outcomes at discharge were explored by multivariate linear regression analysis, and sensitivity analysis was performed using propensity score matching.</p><p><strong>Results: </strong>The two groups were comparable in baseline demographics, sleep parameters and psychiatric symptoms. During hospitalisation, both groups showed substantial improvement in sleep quality and psychiatric symptoms compared with those upon admission. The morning aHF-rTMS group had significantly lower total PSQI scores at discharge (p < 0.001) and longer nighttime sleep duration (β = 0.58, p < 0.001) than the afternoon aHF-rTMS group. Sensitivity analysis showed that morning aHF-rTMS remained associated with low total PSQI scores at discharge (β = -1.83, p < 0.001). No statistically significant differences in PANSS total scores and MoCA scores at discharge were found between the two groups (both p > 0.05). The overall incidence of adverse reactions was 44.44%, slightly higher in the morning group than in the afternoon group (54.02% vs. 35.48%, p = 0.012).</p><p><strong>Conclusions: </strong>The timing of aHF-rTMS treatment may be associated with sleep-related treatment outcomes in hospitalised patients with schizophrenia. Compared with afternoon treatment, morning aHF-rTMS was associated with better subjective sleep quality and longer nighttime sleep duration.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"612-625"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatrists' Knowledge, Attitudes, and Practices Regarding the Use of Modified Electroconvulsive Therapy in Adolescents With Major Depressive Disorder: A Cross-Sectional Survey in Chongqing, China.","authors":"Jingran Li, Xiwen Tan, Ruishen Li, Ning Du, Yang Zhou, Wo Wang","doi":"10.62641/aep.v54i3.2197","DOIUrl":"10.62641/aep.v54i3.2197","url":null,"abstract":"<p><strong>Background: </strong>Adolescent major depressive disorder (MDD) is a serious condition often resistant to treatment. Despite established efficacy in adults, modified electroconvulsive therapy (MECT) remains limited and controversial in youth. This study examined psychiatrists' knowledge, attitudes and practices (KAPs) regarding MECT for adolescent MDD, along with their interrelationships and associated factors.</p><p><strong>Methods: </strong>A cross-sectional online survey was conducted (May-July 2025) amongst psychiatrists in Chongqing, China. Using a validated KAP questionnaire, data were collected via WeChat and examined via descriptive, correlation and regression analyses.</p><p><strong>Results: </strong>Amongst the 125 questionnaires distributed, 113 valid responses were analysed (90.4%). Psychiatrists showed moderate knowledge (3.31 ± 0.88), positive attitude (3.68 ± 0.51) and moderate practice (3.09 ± 0.98) levels regarding MECT. KAPs were positively correlated. Higher professional level (attending physician: β = 0.374, p = 0.007; associate senior or above: β = 0.470, p = 0.004) significantly predicted greater knowledge. Better knowledge (β = 0.225, p = 0.028) predicted more positive attitude. Higher knowledge (β = 0.496, p < 0.001) and attitude (β = 0.226, p = 0.006) significantly predicted greater MECT-related practice. Working in a specialized psychiatric hospital (β = -0.525, p < 0.001) and clinical experience greater than 20 years (β = 0.324, p = 0.030) were significantly associated with practice.</p><p><strong>Conclusions: </strong>Psychiatrists in Chongqing showed positive attitude but only moderate knowledge and practice regarding MECT for adolescent MDD. Enhancing clinician education and addressing patient- and system-level barriers may help promote appropriate MECT use.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"680-691"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148314903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the MOLDES Questionnaire in a Clinical Sample of Patients With Psychotic Spectrum Disorders.","authors":"Juan Jesús Muñoz García, Ricardo M Hodann-Caudevilla, Alfonso García Castaño, Sergio Aguilera Garrido, Rafael Durán Tischhauser, Álvaro Pico Rada, Rafael Salom","doi":"10.62641/aep.v54i3.2176","DOIUrl":"10.62641/aep.v54i3.2176","url":null,"abstract":"<p><strong>Background: </strong>Psychotic spectrum disorders are associated with persistent impairments in psychosocial functioning that are not fully explained by symptom severity, particularly in individuals with chronic courses and prolonged hospitalization. Beyond psychopathological symptoms, relatively stable cognitive-emotional styles may influence long-term adaptation, subjective recovery, and quality of life in severe mental disorders. To examine the psychometric properties of the MOLDES questionnaire in a clinical sample of patients with psychotic spectrum disorders receiving long-term psychiatric care.</p><p><strong>Methods: </strong>A cross-sectional observational study was conducted in a sample of 83 clinically stable male patients with psychotic spectrum disorders hospitalized in a long-term psychiatric care unit. Internal consistency of the global MOLDES score and its three dimensions (Vital Spontaneity, Adjustment, and Optimization) was assessed using Cronbach's alpha. Convergent and discriminant validity were explored through Spearman's correlations with psychotic symptom severity, depressive symptoms, internalized stigma, and quality of life.</p><p><strong>Results: </strong>The global MOLDES score and its dimensions showed acceptable internal consistency, with Cronbach's alpha values ranging from 0.70 to 0.77. No significant associations were observed between MOLDES dimensions and psychotic or depressive symptom severity, supporting discriminant validity. In contrast, Vital Spontaneity and Adjustment were negatively correlated with internalized stigma, while the Optimization dimension showed a positive association with quality of life.</p><p><strong>Conclusions: </strong>These findings provide preliminary evidence supporting the reliability and validity of the MOLDES questionnaire in patients with chronic psychotic disorders. The instrument appears to capture adaptive cognitive-emotional styles that are largely independent of symptom severity and meaningfully related to relevant psychosocial outcomes, suggesting its potential usefulness as a complementary assessment tool in long-term psychiatric care and rehabilitation-oriented settings.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"602-611"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for First-Attempt Suicide Fatalities: Evidence From the MCOSUL Cohort.","authors":"Eugènia Nicolau-Subires, María Irigoyen-Otiñano, Teresa Jové-Miró, Laura Arenas-Pijoan, Rubèn Gavilà-Esquerdo, Samuel Pámpols-Pérez, Anna Gallart-López, Ana Marina Lao-García, Núria Domènech-Martínez, Andrea Jiménez-Mayoral, Vicent Llorca-Bofí","doi":"10.62641/aep.v54i3.2220","DOIUrl":"10.62641/aep.v54i3.2220","url":null,"abstract":"<p><strong>Background: </strong>Individuals who die by suicide may differ depending on whether the fatal act is their first attempt or follows previous non-fatal attempts. Understanding these differences may help refine prevention strategies.</p><p><strong>Methods: </strong>We conducted a cross-sectional analysis within the MCOSUL Cohort, a clinical registry of all patients treated for a suicide attempt in two general hospitals in Lleida, Spain. We included all cohort members who died by suicide between January 2009 and December 2022. Sociodemographic, clinical, and method-related variables were compared between first-attempt and repeat-attempt fatalities. Variables with p < 0.20 in bivariate analyses were entered into a multivariable logistic regression model to identify independent predictors of first-attempt fatalities.</p><p><strong>Results: </strong>Among 117 suicide deaths, 38 (32.5%) occurred at the first attempt and 79 (67.5%) after one or more prior non-fatal attempts. Repeat-attempt fatalities had a mean of 1.89 (SD = 1.73) attempts from cohort entry to death. In multivariable analysis, unemployment (OR = 0.17, 95% CI: 0.04-0.66, p = 0.011) and recognized disability (OR = 0.20, 95% CI: 0.04-0.80, p = 0.035) were less frequent among first-attempt fatalities, indicating they were more common in those who died after repeated attempts. No significant differences were found for age, sex, alcohol use, psychiatric diagnosis, or fatal attempt method.</p><p><strong>Conclusions: </strong>Unemployment and recognized disability (formal legal/administrative disability certification issued by relevant regional authorities, which may encompass physical and/or psychiatric disabilities) appear to characterize individuals who die by suicide after a series of non-fatal attempts, suggesting a subgroup with a more prolonged suicidal course that may benefit from sustained engagement and prevention strategies.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"657-662"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal Relationship Between Vitamin D and Anxiety and Depression: A Bidirectional Mendelian Randomization Study.","authors":"Ting Wang, Ran Chen, Jiacheng Kong, Qiu Zhang, Shouhong Shu","doi":"10.62641/aep.v54i3.2046","DOIUrl":"10.62641/aep.v54i3.2046","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the causal relationship between serum 25-hydroxyvitamin D (25(OH)D) levels and the risk of depression and anxiety, using Mendelian Randomization (MR) analysis from a genetic variation perspective.</p><p><strong>Methods: </strong>Genome-wide association study (GWAS) summary statistics for 25(OH)D levels, depression and anxiety were retrieved from the IEU Open GWAS Project, specifically from datasets \"ebi-a-GCST90000617\", \"ebia-GCST90013878\", and \"ukb-a-82\". A two-sample MR analysis was conducted with 25(OH)D levels as the exposure and depression and anxiety as outcome variables. Cochran's Q test was used to assess heterogeneity among the instrumental variables, and horizontal pleiotropy was tested using the MR-Egger intercept method. Sensitivity analyses were conducted via the leave-one-out approach.</p><p><strong>Results: </strong>The MR analysis, utilizing 32 single nucleotide polymorphisms (SNPs) as instrumental variables, revealed a significant causal association between 25(OH)D levels and depression, with all MR methods (excluding Simple Mode) yielding p-values < 0.05. The odds ratios (ORs) and 95% confidence intervals (CIs) for the significant methods were: OR = 0.82 [95% CI: 0.68-0.98], OR = 0.85 [95% CI: 0.77-0.95], OR = 0.80 [95% CI: 0.68-0.93] and OR = 0.90 [95% CI: 0.82-0.98]. However, no significant causal relationship was found between 25(OH)D levels and anxiety. In the reverse direction, genetically predicted depression showed a potential causal association with lower 25(OH)D levels (inverse variance weighting (IVW) OR = 0.98, 95% CI: 0.96-1.00, p = 0.02), while no such association was observed for anxiety.</p><p><strong>Conclusions: </strong>This study suggests that higher serum 25(OH)D levels may be associated with a lower risk of depression, highlighting the potential of serum 25(OH)D as an early biomarker for depression prevention and clinical management. However, no causal association was found between 25(OH)D levels and anxiety, warranting further investigation. This study provides a potential vitamin D-related intervention direction for the prevention and clinical management of depression.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"878-890"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional and Behavioural Problems Including Anxiety and Depressive Symptoms Across Tanner Stages in Girls With Central Precocious Puberty: A Retrospective Clinical Study.","authors":"Peili Jin, Duomei Wang","doi":"10.62641/aep.v54i3.2205","DOIUrl":"10.62641/aep.v54i3.2205","url":null,"abstract":"<p><strong>Background: </strong>To examine the Tanner stage-specific patterns of psychological and behavioural problems in girls with central precocious puberty (CPP) and to identify clinical predictors of clinically significant psychological impairment.</p><p><strong>Methods: </strong>This retrospective cross-sectional study included 116 girls with CPP treated between January 2020 and December 2024. Clinical data were extracted from electronic medical records. Pubertal development was classified by breast Tanner staging into stage II (n = 32), stage III (n = 42) and stages IV-V (n = 42). Psychological outcomes were evaluated using the age-standardised Child Behavior Checklist (CBCL) T-scores. For participants aged ≥7 years, depressive and anxiety symptoms were assessed using the Children's Depression Inventory and the Screen for Child Anxiety Related Emotional Disorders. The independent predictors of clinically significant psychological problems were identified through logistic regression analysis, defined as CBCL Total Problems T-score of ≥64, and model performance was assessed using receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>The mean CBCL Total Problems T-score was 58.6 ± 12.4, and 50 girls (43.1%) had clinically significant psychological problems. Psychological burden increased across Tanner stages. The CBCL Total T-scores were 52.4 ± 10.8 in stage II, 58.6 ± 11.6 in stage III and 65.8 ± 13.2 in stages IV-V (p < 0.001). The prevalence of clinically significant problems increased from 21.9% to 40.5% and 61.9% (p = 0.002). Internalising symptoms showed a stronger stage-related pattern than externalising symptoms. Early age at onset was associated with increased symptom severity (r = -0.385, p < 0.001). Multivariable analysis identified Tanner stages IV-V versus stage II (odds ratio [OR] = 2.94, 95% confidence interval [CI]: 1.44-5.99, p = 0.003), younger age at onset (OR = 0.72, 95% CI: 0.55-0.94, p = 0.016), higher peak luteinising hormone (LH) (OR = 1.45, 95% CI: 1.08-1.95, p = 0.014) and family history of early puberty (OR = 2.18, 95% CI: 1.26-3.77, p = 0.005) as independent predictors. The prediction model showed good discrimination (area under the curve = 0.812, 95% CI: 0.738-0.886).</p><p><strong>Conclusions: </strong>Girls with CPP experience substantial psychological burden, and risk increases with pubertal stage. Advanced Tanner stage, earlier pubertal onset, increase in peak LH and family history are indicators for enhanced psychological monitoring and support.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"714-725"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148314868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Humanistic Postoperative Care Integrated With the 6S Management Model on Postoperative Delirium and Psychiatric Symptoms in Patients With Schizophrenia Undergoing Surgery.","authors":"Junxia Tong, Meijuan Lan, Yanling Xiao, Xiaoli Liu","doi":"10.62641/aep.v54i3.2239","DOIUrl":"10.62641/aep.v54i3.2239","url":null,"abstract":"<p><strong>Background: </strong>To explore the effects of humanistic postoperative nursing integrated with the 6S management model on psychiatric symptoms, postoperative delirium and stress response in patients with schizophrenia undergoing surgery.</p><p><strong>Methods: </strong>This study adopted a retrospective research design, selecting 80 schizophrenia patients who underwent elective general surgery treatment at People's Hospital of Pingyang between 1 August 2023 and 1 August 2025 as the research subjects. Based on the different treatment methods, the study subjects were divided into a control group (n = 40, receiving routine care) and an observation group (n = 40, receiving humanistic postoperative care integrating the 6S management model on the basis of routine care). Statistical analysis was used to examine the incidence of postoperative delirium, incidence of complications, stress response levels before and after nursing care, social function scores, Positive and Negative Syndrome Scale (PANSS) scores, and mental status scores in both groups.</p><p><strong>Results: </strong>The incidence of postoperative delirium and complications was lower in the observation group than in the control group. There were no significant differences in stress response levels, social function scores, PANSS scores, and mental status scores between the two groups before nursing care (p > 0.05). After nursing care, the observation group had lower stress response levels, PANSS scores, mental status scores and higher social function scores than the control group (p < 0.001).</p><p><strong>Conclusions: </strong>Humanistic postoperative nursing integrated with the 6S management model can reduce the incidence of postoperative delirium, complications, alleviate stress response, improve social function, and reduce psychiatric symptoms in patients with schizophrenia undergoing surgery.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"626-634"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortality Risks in Patients With Schizophrenia in Shanghai: A Longitudinal Cohort Study.","authors":"Yu Zhou, PanPan Zhang, Feng Wang, WeiBo Zhang, YiHua Jiang","doi":"10.62641/aep.v54i3.2022","DOIUrl":"10.62641/aep.v54i3.2022","url":null,"abstract":"<p><strong>Background: </strong>Schizophrenia is a severe mental disorder associated with significantly higher mortality risk than the general population, constituting a major public health challenge. Clarifying temporal trends in mortality among patients with schizophrenia helps inform targeted clinical and public health interventions. To assess changes in mortality rates over the last 2 years in patients with schizophrenia from one district of Shanghai, China.</p><p><strong>Methods: </strong>This longitudinal cohort study assessed the mortality of individuals with schizophrenia (n = 5234) from April 1, 2021, to March 31, 2023. The early cohort (up to March 31, 2022) contained 5207 individuals and the late cohort (up to March 31, 2023) contained 5114 individuals. Partitions of Pearson's chi-square statistic were used to conduct pairwise comparisons. A multivariable Cox proportional hazards model was used to assess the effects of different factors on mortality risk. Data were drawn from the official Shanghai database used for following-up individuals with severe mental health disorders.</p><p><strong>Results: </strong>The total number of deaths was 370. Of these, 120 occurred in the early cohort (2.30% of the cohort) and 250 in the late cohort (4.89% of the cohort). Individuals with schizophrenia in the late cohort had a 5.08- fold increased mortality risk than individuals in the general population. In the early cohort, mortality rates remained relatively stable (0.29%-0.48%). There were peaks in mortality rates (2.23%) in December 2022 and January 2023. Men had a higher risk of mortality than women (hazard ratio [HR], 1.294; 95% confidence interval [CI], 1.035-1.618; p = 0.024). Age was a contributing factor to the mortality of people with schizophrenia (HR, 1.048; 95% CI, 1.040- 1.056; p < 0.001). Being unmarried (HR, 1.956; 95% CI, 1.522-2.513; p < 0.001), divorced (HR, 1.481; 95% CI, 1.010-2.170; p = 0.044), or widowed (HR, 1.334; 95% CI, 0.958-1.856; p = 0.088) was associated with a high risk of mortality. Age of onset (HR, 1.046; 95% CI, 1.037- 1.054; p < 0.001) and illness duration (HR, 1.044; 95% CI, 1.037-1.051; p < 0.001) were associated with high mortality risk. The late cohort showed a higher mortality rate than the early cohort (HR, 2.427; 95% CI, 1.467-4.014; p = 0.001). The mortality of patients with schizophrenia was not significantly related to education level, economic status, or symptom onset.</p><p><strong>Conclusions: </strong>These findings highlight trends in schizophrenia mortality since April 2021. Compared with the general population, individuals with schizophrenia had higher mortality risk, particularly adults aged ≥65 years and women with low education.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"635-643"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148314871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resilience and Social Support as Predictors of Life Satisfaction in Healthy Older Adults: A Moderation Analysis.","authors":"Lorena González-García, Aranzazu Duque, Mireia Molins, Marta Aliño, Francisco Molins, Patricia Mesa-Gresa","doi":"10.62641/aep.v54i3.2218","DOIUrl":"10.62641/aep.v54i3.2218","url":null,"abstract":"<p><strong>Background: </strong>Previous literature has highlighted the importance of psychosocial factors such as the perception of an adequate social support network or the subjective experience of life satisfaction in promoting well-being in older adults and facilitating healthy aging processes. The objective of the present study was to analyze the possible relationship between the level of resilience and social support in healthy older adults, and how these variables may influence experiences of life satisfaction. Furthermore, potential moderation relationships between these variables were analyzed.</p><p><strong>Methods: </strong>The sample consisted of 42 healthy older adults (71.4% women), with a mean age of 66.57 years (standard deviation (SD) = 5.82). Participants completed a battery of questionnaires that included a sociodemographic questionnaire, the Connor-Davidson Resilience Scale (CDRISC), the Duke-UNC Functional Social Support Questionnaire (Duke-UNC-11), and the Satisfaction With Life Scale (SWLS).</p><p><strong>Results: </strong>The results of the multiple regression analyses indicate that resilience and social support positively and significantly predict life satisfaction. Furthermore, moderation analyses indicate that social support moderates the relationship between resilience and life satisfaction, jointly explaining 44.98% of the variance of this indicator of wellbeing. Specifically, the positive association between resilience and life satisfaction was stronger at lower levels of perceived social support.</p><p><strong>Conclusions: </strong>These findings suggest that resilience may play a particularly relevant role in life satisfaction when perceived social support is limited. However, the small sample size, the predominance of women, and the selective recruitment of healthy older adults warrant caution when generalizing the results. Overall, the findings support the need to expand the study of the correlations of well-being in old age, as well as to develop intervention programs aimed at promoting optimal aging that include strategies to improve resilience and foster functional social support networks.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"854-866"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Comfort Nursing in Operating Room on Anxiety Depression and Postoperative Recovery in Thyroidectomy Patients With Coexisting Sleep Disorders.","authors":"Wenjing Wu, Xiulan Huang, Qianwen Xu, Mei Dai, Jingjing Huang","doi":"10.62641/aep.v54i3.2238","DOIUrl":"10.62641/aep.v54i3.2238","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the effects of comfort nursing in the operating room on anxiety, depression and postoperative recovery in thyroidectomy patients with sleep disorders.</p><p><strong>Methods: </strong>This retrospective analysis included 156 propensity-score-matched patients undergoing thyroidectomy at Taizhou Second People's Hospital (January 2023- September 2025). The patients were assigned to conventional care (n = 78) or comfort nursing (n = 78). Outcomes included Hospital Anxiety and Depression Scale (HADS), Pittsburgh Sleep Quality Index (PSQI), polysomnography (PSG), Quality of Recovery-15 (QoR-15), Visual Analogue Scale (VAS), thyroid cancer-specific quality of life (THYCA-QoL), recovery indices, complications and satisfaction.</p><p><strong>Results: </strong>Repeated-measures ANOVA revealed significant time, group and interaction effects for HADS-A, HADS-D and PSQI scores (all p < 0.001). Both groups improved postoperatively, with the comfort group showing greater reductions at 5 days and 4 weeks (p < 0.05). PSG parameters (total sleep time, sleep efficiency, REM%, sleep latency and microarousals) also improved in both groups, with superior outcomes in the comfort group (p < 0.05). Comfort nursing was associated with short times to first flatus and ambulation, reduced hospital stay, low choking incidence and high normal swallowing rate at 72 hours (p < 0.05). Complication rates did not differ between groups (p > 0.05). The comfort group achieved higher QoR-15 and lower VAS scores on days 1-3 (p < 0.001) and lower THYCA-QoL anxiety, psychological and sensory scores at 4 weeks (p < 0.001). Satisfaction was higher in the comfort group (84.62% vs. 69.23%, p < 0.05).</p><p><strong>Conclusions: </strong>Operating room comfort nursing alleviates anxiety and depression, improves sleep architecture, promotes early recovery and enhances quality of life and satisfaction in thyroidectomy patients with sleep disorders.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"54 3","pages":"701-713"},"PeriodicalIF":2.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}