Actas espanolas de psiquiatria最新文献

{"title":"Impact of 16S rRNA on Intestinal Flora Alterations and Early Diagnosis in Early Alzheimer's Disease Patients.","authors":"Danping Lv, Xiuqin Lin, Xinyuan Zhang, Qundi Shen","doi":"10.62641/aep.v53i2.1682","DOIUrl":"10.62641/aep.v53i2.1682","url":null,"abstract":"<p><strong>Background: </strong>Alzheimer's Disease (AD), a complex clinical condition, relies on neuropsychological assessments for early diagnosis. Recently, the gut-brain axis has been recognized as crucial in AD development, with dysbiosis in gut microbiota implicated in disease progression. Utilizing 16S rRNA analysis provides comprehensive monitoring of gut microbiota, potentially revealing biological markers for Early Alzheimer's Disease (EAD). Therefore, this study aimed to investigate the diagnostic impact of 16S ribosomal RNA (rRNA) on changes in intestinal flora among EAD patients.</p><p><strong>Methods: </strong>This study analyzed stool samples from 50 AD patients and 50 healthy controls between June 2022 and June 2023. Based on the disease stage, patients were categorized into EAD (n = 14) and Late Alzheimer's Disease (LAD) groups (n = 36). The V3-V4 region was sequenced using 16S rRNA quantitative Polymerase Chain Reaction (qPCR) to compare the composition of gut microbiota and differences in abundance among the three experimental groups.</p><p><strong>Results: </strong>The abundance and diversity of gut microbiota significantly increased in EAD patients compared to the healthy control group. Furthermore, 39 genera showed considerable variations between EAD and LAD patients and healthy controls, with notable increases in the abundance of Bryantella, Gemmiger, Desulfovibrio, Collinsella, and Odoribacter among EAD patients. Additionally, significant differences were observed across the Desulfovibrioales and Verrucomicrobiales, which could help distinguish EAD patients (Area Under the Curve (AUC) range 0.854, 0.966, p < 0.05).</p><p><strong>Conclusion: </strong>16S rRNA technology can be used to identify EAD patients, with the Desulfovibrioales and Verrucomicrobiales indicators serving as potential biological markers.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"208-221"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stressful Life Events and Neuroticism among Chinese Women with Recurrent Major Depressive Disorder.","authors":"Fengfeng Chu, Chu Wang, Shufei Tao, Jingfang Gao, Xiangzhen Zhu, Danhong Tao, Bijun Chen, Ming Tao","doi":"10.62641/aep.v53i2.1730","DOIUrl":"10.62641/aep.v53i2.1730","url":null,"abstract":"<p><strong>Background: </strong>Depression is associated with a high incidence of stressful life events (SLEs) and neuroticism. However, the impact of SLEs and neuroticism on the recurrence of major depressive disorder (MDD) remains unclear. Therefore, we aimed to identify the potential causal relationship between SLEs, neuroticism, and depression recurrence.</p><p><strong>Methods: </strong>This study included 5561 female patients with recurrent MDD (ages 30-60) and 4257 healthy volunteers (ages 40-60) from the China, Oxford, and Virginia Commonwealth University Experimental Research on Genetic Epidemiology (CONVERGE) study. We compared the female patients with recurrent MDD to a gender and age-matched group of healthy volunteers. Odds ratios (ORs) were calculated using logistic regression analysis to assess the impact of SLEs on depression onset. Furthermore, we employed bootstrapping sampling procedures to explore the mediating role of neuroticism between SLEs and the number of depressive episodes.</p><p><strong>Results: </strong>SLEs contributed to the occurrence of major depression, with rape (OR = 19.14, p = 0.004), serious neglect (OR = 3.65, p < 0.001), legal problems (OR = 2.51, p < 0.001), and divorce or relationship breakup (OR = 2.14, p < 0.001) being significantly associated with the onset of MDD. Following MDD onset, certain SLEs, such as the death of a family member (Z = 3.64, p < 0.001), unemployment (Z = 5.63, p < 0.001), job termination (Z = 6.43, p < 0.001), and financial crisis (Z = 5.53, p < 0.001), led to a significant increase in the number of depressive episodes. Furthermore, mediation analysis demonstrated that events such as divorce or relationship breakup (p < 0.05), rape (p < 0.05), financial crisis (p < 0.05), and physical abuse (p < 0.05) indirectly affected the number of depressive episodes through neuroticism.</p><p><strong>Conclusions: </strong>Our study demonstrates that SLEs in different categories have different effects on the onset and recurrence of MDD, and their effects regarding personal maltreatment, interpersonal relationship, and finance on the recurrence of depression are mediated by neuroticism.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"348-358"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Self-objectification and Adolescent Appearance Anxiety: A Mediated Model with Moderation.","authors":"He Zhang, Hongyu Li, Can Jiang, Yafeng Tu, Mengyao Xi","doi":"10.62641/aep.v53i2.1742","DOIUrl":"10.62641/aep.v53i2.1742","url":null,"abstract":"<p><strong>Background: </strong>The physical appearances of an individual are frequently scrutinized and evaluated by others in daily life. The rise of social media has intensified this scrutiny, leading to increased attention to and comparison of the appearance of an individual with others, leading to psychological challenges such as appearance anxiety. This study, from the perspective of self-objectification, explored the influence of self-objectification on appearance anxiety and the role of social appearance comparison and self-compassion in the relationship between self-objectification and appearance anxiety.</p><p><strong>Methods: </strong>A questionnaire survey was conducted among 842 adolescents using validated instruments, including the Self-objectification Scale, the Social Appearance Comparison Scale, the Self-compassion Scale, and the Appearance Anxiety Scale. Of these, 766 valid questionnaires were completed and analyzed.</p><p><strong>Results: </strong>(1) Self-objectification was a significant positive predictor of appearance anxiety. (2) Social appearance comparison partially mediated the relationship between self-objectification and appearance anxiety. (3) The second half of the mediation process in which self-objectification affects appearance anxiety through social appearance comparison was moderated by self-compassion.</p><p><strong>Conclusion: </strong>The effect of self-objectification on appearance anxiety is a mediated process with moderation.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"359-365"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the Correlation between Frailty Index, Clinical Characteristics, Use of Anti-Epileptic Drug, and Prognosis in Elderly Patients with Epilepsy.","authors":"Jianzhong Wang, Hengzhang Ma, Xiaodan Lin, Lixian Li, Zhixiong Zheng, Xiaohua Huang","doi":"10.62641/aep.v53i2.1729","DOIUrl":"10.62641/aep.v53i2.1729","url":null,"abstract":"<p><strong>Background: </strong>Epilepsy is a common neurological disorder among the elderly, often leading to significant morbidity. Therefore, it is necessary to study the correlation between the frailty index, clinical characteristics of epilepsy, use of anti-epileptic drug, and the prognosis of elderly patients with epilepsy.</p><p><strong>Methods: </strong>This retrospective study included 106 elderly patients with epilepsy who were treated at the Affiliated Mindong Hospital, Fujian Medical University, China, between January 2018 and December 2022. Based on the severity of the prognosis, the seizures were classified into the major seizure group (tonic-clonic), minor seizure group (absence, myoclonus, clonus, tonic, atonic and partial seizures), and no seizure group. Furthermore, the relationship between the frailty index, clinical characteristics, use of epilepsy drugs, and the degree of epileptic seizures was assessed using the Logistic regression analysis.</p><p><strong>Results: </strong>Univariate analysis indicated that older age (p < 0.001), longer disease duration (p = 0.009), and the presence of comorbid conditions such as diabetes (p = 0.002) and coronary heart disease (p < 0.001) were all associated with seizure severity. Additionally, frailty was significantly related to seizure severity, with the non-frailty group having fewer major seizures compared to the pre-frailty and frailty groups (p < 0.001). Similarly, regular medication use (p < 0.001) and the number of drugs taken (p < 0.001) were significant factors, with irregular medication use and single-drug regimens being more common in patients with more severe seizures. Multivariate Logistic regression analysis indicated that a higher frailty index (p = 0.033), age over 70 years (p = 0.015), longer disease duration (p = 0.003), the presence of coronary heart disease (p < 0.001), and regular medication use (p = 0.022) were all significantly associated with more severe seizures.</p><p><strong>Conclusion: </strong>Frailty index, age, disease duration, coronary heart disease, and regular medication are related to the prognosis of elderly patients with epilepsy. These findings highlight the significance of comprehensive management strategies to improve clinical outcomes in this group of patients.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"284-291"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Behavioral Therapy Improves the Quality of Life for Patients with Mild to Moderate Depression due to Glaucoma or Cataracts: A Retrospective Study.","authors":"Yinchen Lin, Hong Zhang, Chunliu Shi, Na Yang, Xiaoqing Li, JinHua Gan","doi":"10.62641/aep.v53i2.1673","DOIUrl":"10.62641/aep.v53i2.1673","url":null,"abstract":"<p><strong>Background: </strong>Individuals affected with glaucoma and cataracts are more likely to experience depressive symptoms, which can affect their overall quality of life (QOL) and functioning. Therefore, this retrospective cohort study aimed to evaluate the impact of cognitive behavioral therapy (CBT) on glaucoma or cataracts patients with mild to moderate depression.</p><p><strong>Methods: </strong>This study included patients with mild to moderate depression resulting from glaucoma or cataracts in our hospital from January 2023 to December 2023. The study participants were divided into an untreated group and a cognitive behavioral therapy group based on different intervention methods. We assessed depressive symptoms using the Center for Epidemiologic Studies Depression Scale (CES-D) and Patient Health Questionnaire-9 (PHQ-9). QOL was evaluated using the Chinese translation version of the European Quality of Life-5 Dimensions scale (EQ-5D), Short Form Health Survey (SF-36), National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Additionally, cognitive behavioral therapy (CBT) was administered to a subgroup of patients with mild to moderate depression, and the impact of CBT on the well-being of the patients was analyzed.</p><p><strong>Results: </strong>This study included 3010 individuals, consisting of untreated patients (n = 2151) and those who received cognitive behavioral therapy (n = 859). Post-intervention analysis revealed that compared to baseline, the CES-D scores (p < 0.001), PHQ-9 scores (p < 0.001), and HADS anxiety subscale scores (p < 0.001) were significantly reduced in the CBT group. Furthermore, the CBT group demonstrated a significant increase in EQ-5D scores (p < 0.001) and SF-36 mental component scores (p < 0.001) post-intervention compared to baseline.</p><p><strong>Conclusion: </strong>These findings offer significant insights into the prospective effectiveness of CBT in improving depressive symptoms and QOL in individuals with glaucoma or cataracts.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"245-252"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Morita Therapy for Treating Hospitalized Patients with Depression.","authors":"Haiqun Shen, Yiyu Mao, Yu'e Fei, Yuchao Lu","doi":"10.62641/aep.v53i2.1714","DOIUrl":"10.62641/aep.v53i2.1714","url":null,"abstract":"<p><strong>Background: </strong>Depression is a common mental illness worldwide. Morita therapy is a novel and effective intervention method for treating depression patients. This study aimed to investigate the effects of modified Morita therapy on social functioning and quality of life in individuals suffering from depression.</p><p><strong>Methods: </strong>The data of depressive patients hospitalized in Kangci Hospital of Jiaxing from June 2021 to May 2022 were collected and analyzed by propensity score matching (PSM). The control group received antidepressant treatment and standard psychiatric care (n = 30), while the study group received modified Morita therapy on the basis of standard treatment (n = 30). Both experimental groups received a six-week intervention. The 17-item Hamilton Depression Scale (HAMD-17) was used to assess the severity of depression before and after the intervention. Hamilton Anxiety Scale (HAMA) was used to assess the anxiety level of patients. Social Dysfunction Screening Scale (SDSS) was used to evaluate the social functioning of the patients. Generic Quality of Life Inventory-74 (GQOLI-74) was implemented to evaluate the quality of life of patients based on four dimensions: physical function, psychological function, social function, and material life status through 74 items.</p><p><strong>Results: </strong>After six weeks of intervention, the study group exhibited significantly reduced HAMD-17, HAMA, and SDSS scores compared to the control group (p < 0.05). Furthermore, significant improvements were observed in physical function, psychological function, social function, material well-being domains, and the overall GQOLI-74 questionnaire scores within the study group compared to the control group (p < 0.05).</p><p><strong>Conclusion: </strong>Modified Morita therapy effectively alleviates depression and anxiety levels among depressed patients while enhancing their social functioning and improving their quality of life, thus highlighting its clinical applications.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"324-330"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptability of VloV, a Mobile App Developed in Latin America for People with Substance Use Disorder among an Intensive Outpatient Treatment.","authors":"Diana Milena Berrio Cuartas, Carola Cassinelli, Luciana Noemi Garcia, Federico Pavlovsky","doi":"10.62641/aep.v53i2.1701","DOIUrl":"10.62641/aep.v53i2.1701","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Digital therapeutic tools seem to be helpful for substance use disorders (SUD), but there are few studies in Latin America about this approach. Our group of therapists developed VloV (an abbreviation for Pavlovsky), a mobile app that attempts to digitize practical tools along with strengthening the therapeutic alliance and user practice.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Method: &lt;/strong&gt;We conducted a mixed-method pilot study between August 2021 and January 2022 to collect data about the patient experience using VloV and the therapeutic alliance among 23 patients. VloV is a Spanish mobile app available for free that focuses on SUD and covers therapeutic elements and tools from an intensive outpatient treatment program. A monthly PDF report containing the patient's daily interactions is generated and can be shared via e-mail with the therapist for follow-up. We run three questionnaires (Q), Q1 regarding technology use indications Q2 to review content information and the utility of the different elements of VloV, and Q3 to collect qualitative data about participants' experiences and perceptions. Several aspects of the therapeutic alliance were evaluated using the patient version of the Working Alliance Inventory in its short version (WAI-S-P). Several aspects of the therapeutic alliance were assessed using the patient version of the Working Alliance Inventory in its short version (WAI-S-P). The level of agreement between the raters-provider and monthly VloV reports-was calculated for treatment variables in patients and their mood state records. For some sub-analysis, patients were divided into two categories, those who have a daily app's use and those who have a weekly or sporadic use.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Patient characteristics were similar to the statistics of the treatment center data, including the dropout rate; only 15 out of 23 (65.2%) patients completed the 12 weeks of the pilot study. Participants reported daily use of the technology, but only 5.0% searched for health topic information on the web. Patients expressed positive feedback by using the app and found some functional aspects in VloV that contributed to their treatments and self-care as mood scale record, money earned display, sobriety calculator, and treatment skill functions. However, the \"red button\" function, which allows the patient to ask for help, was not found to be of much use. We found a correlation between the frequency app's use and a higher accuracy in the provider register of treatment related to variables. Although working alliance therapeutic scores were mainly high and non-differences were found.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This is the first study on a mobile application for SUD developed in our region, and although it is only a preliminary study, it pointed out important lessons about incorporating digital therapeutic tools into mental health treatment in an intensive outpatient treatments (IOT) setting.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical trial ","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"304-314"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Mindfulness Therapy on Breast Cancer Patients with Depression or Anxiety: A Systematic Review and Meta-analysis.","authors":"Jingjing Yan, Fenhua Wang, Xianghua Yu","doi":"10.62641/aep.v53i2.1949","DOIUrl":"10.62641/aep.v53i2.1949","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer (BC) is the most common malignant tumor threatening women's health globally, with rising incidence rates and significant psychological impacts, particularly in China, where the prevalence of depressive and anxious mood disorders among BC patients is notably higher than the global average. To evaluate the effect of mindfulness therapy on anxiety and depressive symptoms in breast cancer patients, as psychological distress significantly affects their quality of life and often persists despite medical treatment.</p><p><strong>Methods: </strong>A computerized search of Web of Science, PubMed, ScienceDirect, Cochrane Library, and Embase databases was conducted for randomized controlled trials involving the effects of positive thinking interventions on anxiety and depressive symptoms in breast cancer patients. The search was conducted from the time of database construction to December 2023. Two researchers completed literature screening, data extraction, and quality assessment, and then analyzed using RevMan 5.4 software.</p><p><strong>Results: </strong>A total of 15 studies involving 1823 patients were included. Meta-analysis results demonstrated that anxiety scores [mean difference (MD) = -0.67, 95% CI (-1.05, -0.29), p = 0.0005] and depression scores [MD = -2.26, 95% CI (-2.91, -1.61), p < 0.00001] were lower in the positive mindfulness intervention group than in the control group after the intervention, and the difference was statistically significant. Meanwhile, the follow-up time (>8 weeks vs ≤8 weeks) had little effect on the improvement of patients' depression and anxiety scores. The distribution of studies was unsymmetrical, and there was a certain degree of publication bias.</p><p><strong>Conclusion: </strong>This study provides scientific evidence and practical guidance for psychological care in breast cancer patients, supporting the effectiveness of mindfulness-based interventions (excluding mindfulness-based cognitive therapy (MBCT)) in alleviating anxiety and depression. Future research should focus on high-quality randomized controlled trials to confirm and expand these findings and explore more effective intervention strategies.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"422-432"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Childhood Trauma and Depression in Early Adulthood: The Roles of Resilience and Personality Type.","authors":"Binbin Wang, Jingyi Zhang, Chengqi Cao, Ling Xu, Mingyue Gao, Qin Zhang, Kunlin Zhang","doi":"10.62641/aep.v53i2.1690","DOIUrl":"10.62641/aep.v53i2.1690","url":null,"abstract":"<p><strong>Background: </strong>The relationship between childhood trauma and depression in early adulthood is complex and influenced by factors such as resilience and personality type. This study aims to investigate the mediating role of resilience and the moderating role of personality types in this relationship.</p><p><strong>Methods: </strong>A total of 1059 undergraduates (mean age = 19.87 ± 1.82 years; 48.1% men, 51.9% women) were surveyed. The Big Five Personality Inventory (BFI) was used to assess the personality dimensions of the participants, which were further analyzed using latent profile analysis (LPA). Childhood trauma experiences were evaluated using the short form of the Childhood Trauma Questionnaire (CTQ), while resilience was measured using the Connor-Davidson Resilience Scale (CD-RISC). Depressive symptoms were assessed using the Center for Epidemiological Studies-Depression Scale (CES-D). All scales demonstrated high reliability and validity.</p><p><strong>Results: </strong>The findings indicated a positive correlation between childhood trauma and depression, mediated by resilience. Personality types moderated this mediation, with significant indirect effects observed only for individuals categorized as Type 2.</p><p><strong>Conclusions: </strong>This study provides insight into the mechanisms of depression in early adulthood, suggesting that an intervention targeting resilience and considering personality type may be beneficial. The result highlight the importance of a human-centered approach in understanding the interaction among personality traits and their potential moderating effect on the relationship between childhood trauma and depression symptoms.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"292-303"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Anxiety and Depression Based on Video Game Addiction with the Mediating Role of Social Support.","authors":"Zahra Jahanbakhshi, Nima Rezvani, Motahare Pourhasan, Shirin Ahmadi, Sayed Jafar Ahmadi","doi":"10.62641/aep.v53i2.1745","DOIUrl":"10.62641/aep.v53i2.1745","url":null,"abstract":"<p><strong>Background: </strong>Today, computer games have become one of the most popular forms of entertainment, especially among teenagers. While games may have various benefits, video games are shown to have different consequences for players, especially those who are younger, and can be highly addictive. The present research investigated the effect of computer game addiction on anxiety and depression in adolescents with the mediating role of social support.</p><p><strong>Methods: </strong>Overall, 304 adolescents aged 12-18 years old living in Tehran were included in the research through a convenient method. The required data were collected using the Trait-state Anxiety Questionnaire, Depression Scale, Social Support Questionnaire, and Computer Game Addiction Questionnaire and then analyzed using the structural equation model in AMOS software.</p><p><strong>Results: </strong>The results revealed that addiction to computer games had a significant effect on anxiety and depression. In addition, social support could act as a mediator in this relationship and reduce the harmful effects of computer game addiction on anxiety and depression.</p><p><strong>Discussion: </strong>According to the findings, to reduce anxiety and depression related to computer game addiction, it is necessary to pay attention to the improvement of social support for people through providing appropriate treatment plans, informing family and friends, and strengthening social connections and support networks.</p><p><strong>Conclusion: </strong>It is suggested that appropriate treatment programs be designed and implemented to reduce anxiety and depression in individuals with computer game addiction. These programs could include time management, behavior modification, enhancement of communication and social skills, and the provision of adequate social support through families, friends, and professional communities.</p>","PeriodicalId":7251,"journal":{"name":"Actas espanolas de psiquiatria","volume":"53 2","pages":"267-274"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}