Cancer health disparities最新文献

Breast and Cervical cancer disparities in Alabama: current scenario, ongoing efforts to reduce the disparity gaps, and what more we could be doing. 阿拉巴马州乳腺癌和宫颈癌的差异:目前的情况，正在努力减少差距，以及我们还可以做些什么。

Cancer health disparities Pub Date : 2022-01-01

Kiley Caroline Brady, Claudia Paige Stephens, Sarabjeet Kour Sudan, Ajay Pratap Singh, Santanu Dasgupta, Seema Singh

{"title":"Breast and Cervical cancer disparities in Alabama: current scenario, ongoing efforts to reduce the disparity gaps, and what more we could be doing.","authors":"Kiley Caroline Brady, Claudia Paige Stephens, Sarabjeet Kour Sudan, Ajay Pratap Singh, Santanu Dasgupta, Seema Singh","doi":"","DOIUrl":"","url":null,"abstract":"Over the years, we have made considerable progress in our understanding of the biology of various cancers leading to advancements in their management strategies. Consequently, we have witnessed steady improvements in survival rates of cancer patients post-diagnosis. The progress; however, has been slow for some cancer types and the advances in cancer care have not benefited all the communities equally in the United States. The state of Alabama has one of the most diverse demographics in the country and as a result, we witness significant health disparities among our populations. Breast and cervical cancers are the two major cancer types that disparately affect the women in our state. Here, we describe the extent of disparities in the diagnosis and death rates from these cancers in the state of Alabama and discuss potential underlying causes affecting the health outcomes. We also discuss ongoing efforts undertaken to reduce the disparity gaps and provide a perspective for addressing these disparities more effectively.","PeriodicalId":72512,"journal":{"name":"Cancer health disparities","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909834/pdf/nihms-1839584.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9787465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Racial differences in prostate tumor microenvironment: implications for disparate clinical outcomes and potential opportunities. 前列腺肿瘤微环境的种族差异:对不同临床结果和潜在机会的影响

Cancer health disparities Pub Date : 2022-01-01

Sandeep Goswami, Chandrani Sarkar, Seema Singh, Ajay Pratap Singh, Debanjan Chakroborty

{"title":"Racial differences in prostate tumor microenvironment: implications for disparate clinical outcomes and potential opportunities.","authors":"Sandeep Goswami, Chandrani Sarkar, Seema Singh, Ajay Pratap Singh, Debanjan Chakroborty","doi":"","DOIUrl":"","url":null,"abstract":"Disparities in cancer incidence and outcome are common among the racial and ethnical minorities in the United States and are of significant social and clinical concern. Prostate cancer is the most commonly diagnosed non-cutaneous malignancy in American men and exhibits substantial racial disparities with African American men bearing the highest burden in terms of incidence and mortality. A multitude of factors, including socioeconomic, behavioral, and access to healthcare, have been implicated as the underlying causes of such disparities. More recent data also suggest that there are inherent molecular and biological differences in prostate tumors of patients having distinct racial backgrounds. Tumor microenvironment has tremendous impact on the course of cancer progression and clinical outcome and may also contribute to the racial disparities observed in prostate cancer. Therefore, a better understanding of critical differences in the tumor microenvironment components may provide newer directions to study the biological causes of prostate cancer health disparities and may identify novel therapeutic targets. This review discusses the findings related to the tumor microenvironment differences between African American and Caucasian American prostate cancer patients and makes suggestion regarding their potential significance in prostate cancer disparities.","PeriodicalId":72512,"journal":{"name":"Cancer health disparities","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910060/pdf/nihms-1818770.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9787467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highlights from International Conference on Cancer Health Disparities 2021. 2021 年癌症健康差异问题国际会议要点。

Cancer health disparities Pub Date : 2022-01-01

Murali M Yallapu, Jorge Teniente, Andrew Tsin, Subhash C Chauhan

{"title":"Highlights from International Conference on Cancer Health Disparities 2021.","authors":"Murali M Yallapu, Jorge Teniente, Andrew Tsin, Subhash C Chauhan","doi":"","DOIUrl":"","url":null,"abstract":"The first International Conference on Cancer Health Disparities (ICCHD) was held on August 13-14, 2021, in Harlingen, TX, USA. This two-day ICCHD-2021 was organized by the University of Texas Rio Grande Valley, School of Medicine (UTRGV-SOM). About 200 national and international delegates from 10 countries attended this hybrid meeting in person and through online digital platforms. The event delegates were representatives from National Institutes of Health (NIH), Cancer Prevention and Research Institute of Texas (CPRIT), and the City of Harlingen, in addition to clinicians, faculty, researchers, scientists, bioinformaticians, geneticists, bioethicists, and others. Under the theme of Cancer Health Disparities, this event featured a number of special talks and showcased the work done by researchers from a broad array of disciplines (academia, community, and health care) to identify gaps and/or solutions to multi-faceted heath and health disparity issues impacting minority and underserved populations across the country and worldwide. The conference was comprised of six sessions: Session 1: Introduction to the conference and tackling cancer health disparities; Session 2: Elimination of cancer health disparities; Session 3: Cancer cellular and molecular biology; Session 4: Diversity and Inclusion in cancer research: Session 5: Poster and oral presentations, and Early career investigator talks; Session 6: An award ceremony and closing remarks. This conference report summarizes the meeting's content, discussions, and conclusions.","PeriodicalId":72512,"journal":{"name":"Cancer health disparities","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205099/pdf/nihms-1849069.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9514154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Racial disparities in the genetic landscape of lung cancer. 肺癌基因图谱中的种族差异。

Cancer health disparities Pub Date : 2022-01-01

Shashi Anand, Kunwar Somesh Vikramdeo, Seema Singh, Ajay Pratap Singh, Santanu Dasgupta

引用次数: 0

NACP: Partnership for Native American Cancer Prevention. NACP:美洲原住民癌症预防伙伴关系。

Cancer health disparities Pub Date : 2021-01-01 Epub Date: 2021-09-21

Francine C Gachupin, Jani C Ingram, Kelly A Laurila, Maria C Lluria-Prevatt, Nicolette I Teufel-Shone, Margaret M Briehl

引用次数: 0

Enhancing African American Participation in Biospecimens: A Case in Point for Pancreatic Cancer. 加强非洲裔美国人对生物样本的参与：胰腺癌案例。

Cancer health disparities Pub Date : 2020-12-01 DOI: 10.1158/1538-7755.DISP20-PO-236

Linda Behar-Horenstein, Rueben C Warren, V Wendy Setiawan, Corey Perkins, Thomas D Schmittgen

{"title":"Enhancing African American Participation in Biospecimens: A Case in Point for Pancreatic Cancer.","authors":"Linda Behar-Horenstein, Rueben C Warren, V Wendy Setiawan, Corey Perkins, Thomas D Schmittgen","doi":"10.1158/1538-7755.DISP20-PO-236","DOIUrl":"10.1158/1538-7755.DISP20-PO-236","url":null,"abstract":"Diseases of the pancreas (i.e. chronic pancreatitis, diabetes, and pancreatic cancer) disproportionally affect the African American community. Challenges associated with engaging the African American community in biospecimen research are longstanding. We surveyed a number of pancreas-related biobanks, and data repositories for African American representation. While some of the biobanks and databases surveyed contain biospecimens and data from African American donors at levels that reflect minority representation among the general population, others do not. A number of factors have historically contributed to reduced participation of the African Americans community in biospecimen donation including medical mistrust, lack of transparency, fear, and a poor knowledge and understanding about the use of biospecimens for research. Suggestions for increasing African American participation in organ and biospecimen donation include educational interventions, particularly in community groups, and providing printed and online recruitment materials to patients, patient advocates, and care partners. Increasing awareness of the many benefits of biospecimen donation among African Americans will positively affect health disparities research into pancreatic cancer and other diseases.","PeriodicalId":72512,"journal":{"name":"Cancer health disparities","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294622/pdf/nihms-1633114.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39211827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Liver cancer incidence and mortality: Disparities based on age, ethnicity, health and nutrition, molecular factors, and geography. 肝癌发病率和死亡率:基于年龄、种族、健康和营养、分子因素和地理的差异。

Cancer health disparities Pub Date : 2020-03-01

Santosh Kumar Singh, Rajesh Singh

引用次数: 0

SPEECH: Synergistic Partnership for Enhancing Equity in Cancer Health. 演讲：加强癌症健康平等的协同伙伴关系。

Cancer health disparities Pub Date : 2020-01-01 Epub Date: 2019-05-07

Olorunseun O Ogunwobi, Grace X Ma

引用次数: 0

Cervical cancer outcome by type of health care facilities: National Cancer Database, 2004-2015. 按医疗机构类型分列的宫颈癌结果:2004-2015年国家癌症数据库。

Cancer health disparities Pub Date : 2020-01-01 Epub Date: 2019-04-23

HyounKyoung G Park, Zhixin E Wang, Chenguang Wang, Warner K Huh, Sejong Bae

{"title":"Cervical cancer outcome by type of health care facilities: National Cancer Database, 2004-2015.","authors":"HyounKyoung G Park, Zhixin E Wang, Chenguang Wang, Warner K Huh, Sejong Bae","doi":"","DOIUrl":"","url":null,"abstract":"The National Cancer Database from 2004 to 2015 was analyzed to identify cervical cancer outcomes associated with demographic and clinical characteristics measured by types of facility. Chi-Square tests were used to compare proportions and logistic regression to determine factors associated with cervical cancer outcomes. Women treated at Academic/Research Programs (ARPs) were younger at diagnosis, more likely black, less educated and more in Stage 2, lived further away from treatment facilities, had less comorbidities and better 5-year survival, and were more likely to be alive at 30 and 90 days after surgery compared to other programs. Women treated at Community Cancer Programs were more likely 75 and older at diagnosis, more likely to receive radiation treatment and more in Stage 4, more living in rural areas and less than 10 miles from the facility, and had more comorbidities, and lower 5-year survival compared to other programs. Women treated at Comprehensive Community Cancer Programs were more likely white and educated, had more private insurance, and underwent surgery. Women treated at Integrated Network Cancer Programs were more likely to live in urban, south region, and in Stage 1B2, had more surgery and one comorbidity, and died fewer than 30 days after surgery. The type of facility and treatment had varied effects on mortality and 5-year survival. Considering the different cervical cancer outcomes from different health care facilities, further research is needed to identify what factors influence women to choose a health care facility for their treatment and how this choice can affect different health outcomes.","PeriodicalId":72512,"journal":{"name":"Cancer health disparities","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136613/pdf/nihms-1034624.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39012298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Looking at cancer health disparities without the colored lenses. 不带有色眼镜看癌症健康差异。

Cancer health disparities Pub Date : 2019-08-19 DOI: 10.9777/CHD.2019.1004

M. A. Khan, G. Patel, S. Srivastava, J. Carter, J. Pierce, R. Rocconi, Seema Singh, A. Singh

引用次数: 5