Acta veterinaria Hungarica最新文献_第5页

Epizootiological serosurvey on small ruminant lentiviruses: Prevalence, age and breed effects 小反刍动物慢病毒流行病学血清调查:流行率、年龄和品种影响

4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-10-17 DOI: 10.1556/004.2023.00833

Gülnur Kalaycı, Murat Kaplan, Buket Özkan, Kemal Pekmez, Abdurrahman Anıl Çağırgan, Ramazan Türkmen, Serra Tunalıgil

{"title":"Epizootiological serosurvey on small ruminant lentiviruses: Prevalence, age and breed effects","authors":"Gülnur Kalaycı, Murat Kaplan, Buket Özkan, Kemal Pekmez, Abdurrahman Anıl Çağırgan, Ramazan Türkmen, Serra Tunalıgil","doi":"10.1556/004.2023.00833","DOIUrl":"https://doi.org/10.1556/004.2023.00833","url":null,"abstract":"Abstract In this study, the prevalence of small ruminant lentivirus, i.e. Maedi-Visna and caprine arthritis encephalitis virus infections in sheep and goat populations were investigated through epizootiological serosurveillance in the Aegean region located in western Türkiye in 2018. A total of 1,840 serum samples (595 goats, 1,245 sheep) were collected from 92 villages in the region and examined by indirect ELISA. Thirty-nine goat and 304 sheep sera were found positive for small ruminant lentivirus antibodies. The prevalence was 24.42% in sheep and 6.55% in goats. An average of 18.64% was found in small ruminants in the Aegean region. The prevalence of small ruminant lentiviruses was found to be higher in Pirlak and Pirlak hybrid sheep and in Saanen and Saanen hybrid goats ( P < 0.05). The prevalence was found to increase with age, as it was higher in animals older than 48 months than in the age groups of 0–24 or 25–48 months ( P < 0.05). Moreover, the small ruminant lentivirus prevalence was higher in sheep than in goats ( P < 0.0001). With the epizootiological approach, this study is expected to contribute to the control and prevention of small ruminant lentivirus infections.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135943986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro effects of sodium butyrate, a histone deacetylase inhibitor on canine mammary tumour subtypes 组蛋白去乙酰化酶抑制剂丁酸钠对犬乳腺肿瘤亚型的体外作用

4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-10-17 DOI: 10.1556/004.2023.00899

Ozge Turna, Asuman Deveci Ozkan, Gamze Guney Eskiler, Aslıhan Baykal, Gulay Yuzbasioglu Ozturk

{"title":"In vitro effects of sodium butyrate, a histone deacetylase inhibitor on canine mammary tumour subtypes","authors":"Ozge Turna, Asuman Deveci Ozkan, Gamze Guney Eskiler, Aslıhan Baykal, Gulay Yuzbasioglu Ozturk","doi":"10.1556/004.2023.00899","DOIUrl":"https://doi.org/10.1556/004.2023.00899","url":null,"abstract":"Abstract Malignant canine mammary tumours (CMTs) are subdivided as carcinomas (C), sarcomas (S) and carcinosarcomas (CS) according to their histological type. Due to the varying responses to different treatments, novel therapeutic approaches are required. Sodium butyrate (NaBu) is the first histone deacetylase inhibitor and exhibits anti-cancer activity in different types of human cancers. However, no study is available in the literature evaluating the effects of NaBu on CMT cells. Therefore, for the first time, we aimed to investigate the in vitro efficacy of NaBu on three subtypes of CMT cells. Primary cells were isolated from neoplastic tissues of three dogs with CMT. Cell viability, apoptotic percentage and changes in the cell morphology, apoptosis-associated gene and protein expression levels were evaluated. Our findings showed that NaBu decreased the growth of the cells and increased the percentage of apoptosis in three subtypes of CMT cells. Additionally, NaBu treatment affected the expression levels of genes and proteins associated with apoptosis, especially in S cells. Our preliminary results, for the first time, revealed the efficacy of NaBu in CMT cells and the importance of the histological subtype in NaBu response. However, the molecular classification of CMT and the underlying mechanisms of the different NaBu responses should be further investigated.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135943985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence, characterization and antimicrobial resistance of non-O157 Shiga toxin-producing Escherichia coli isolates from healthy cattle in Tunisia 突尼斯健康牛中非o157产志贺毒素大肠杆菌的流行、特征和耐药性

4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-10-17 DOI: 10.1556/004.2023.00904

Ghassan Tayh, Salma Mariem Boubaker, Rym Ben Khedher, Mounir Jbeli, Monia Dâaloul-Jedidi, Lilia Messadi

{"title":"Prevalence, characterization and antimicrobial resistance of non-O157 Shiga toxin-producing Escherichia coli isolates from healthy cattle in Tunisia","authors":"Ghassan Tayh, Salma Mariem Boubaker, Rym Ben Khedher, Mounir Jbeli, Monia Dâaloul-Jedidi, Lilia Messadi","doi":"10.1556/004.2023.00904","DOIUrl":"https://doi.org/10.1556/004.2023.00904","url":null,"abstract":"Abstract As a continuation of our previous work, here we examined the occurrence, virulence factors and antibiotic resistance of non-O157 Shiga toxin-producing Escherichia coli (STEC) bacteria in faecal samples of healthy cattle in Tunisia. From 260 faecal samples, 236 E. coli isolates were obtained, of which 30 (12.7%) proved to be non-O157:H7 STEC. The presence of STEC-serogroup virulence genes stx1, stx2 , eaeA and ehxA was detected by PCR. Further virulence genes and other genes used for phylogenetic grouping were also examined among the STEC isolates. The most dominant serogroup was O145, followed by O103 and O45. Shiga toxin gene ( stx1 ) was found in 70% of the STEC strains, stx2 and ehxA were detected in 17 isolates (56.7%). Other virulence genes, including fimH , traT, sfa/focDE , iutA , cdt3 , hly, fyuA and ibeA, were detected in 100%, 60%, 46.7%, 46.7%, 36.7%, 10%, 6.7% and 3.3%, of the strains, respectively. More than 70% of the isolates were susceptible to most of the tested antibiotics. We concluded that the presence of STEC O145, O103 and O45 (12.7%), together with the earlier described STEC O157:H7 (4.2%) in cattle, intended for slaughter, may represent a threat to public health. Efficient control measures are needed in the farms and slaughterhouses in Tunisia.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135993990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental exposure of rainbow trout eggs to water mould, Saprolegnia parasitica (Oomycota): intraspecific differences in pathogenicity 虹鳟鱼卵暴露于水霉菌的实验研究:种内致病性差异

4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-10-17 DOI: 10.1556/004.2023.00931

Tímea Hardy, Noémi Erdei, Dóra Sipos, Viktória Verebélyi, Edit Eszterbauer

{"title":"Experimental exposure of rainbow trout eggs to water mould, Saprolegnia parasitica (Oomycota): intraspecific differences in pathogenicity","authors":"Tímea Hardy, Noémi Erdei, Dóra Sipos, Viktória Verebélyi, Edit Eszterbauer","doi":"10.1556/004.2023.00931","DOIUrl":"https://doi.org/10.1556/004.2023.00931","url":null,"abstract":"Abstract In in vivo infection trials, rainbow trout eyed eggs were exposed to three Saprolegnia parasitica (Oomycota) isolates, which differed in biological and genetic characteristics. Infection prevalence, hatching rate, hatching dynamics of fish eggs were quantified, and the study was complemented with histopathology and phylogenetic analyses. We experimentally detected intraspecific differences in the pathogenicity of S. parasitica on rainbow trout eggs. The isolate from rainbow trout eggs was the most virulent to eggs of the same host, whereas isolates from carp skin and fry did not cause as much damage to the eggs. Comparing the outcome of two experimental settings, we confirmed that invasion of fish eggs is more effective by hyphae growth than by the actively moving zoospores. In addition, our findings highlighted that S. parasitica isolates with 100% identical ITS DNA sequences, could differ significantly in virulence. These isolates can be clearly distinguished based on a 650-bp DNA fragment of the DNA-directed RNA polymerase II subunit ( RPB2 ) gene.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":"166 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135945125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sequencing and analysis of micro RNAs in camel milk exosomes. 骆驼奶外泌体中微小RNA的测序和分析。

IF 0.9 4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-09-19 DOI: 10.1556/004.2023.00869

Rinile Wu, Caifeng Yue, Yina Xie, Yuerong Fu, Xin Yu, Zhuoyuan Li, Bin Yang

{"title":"Sequencing and analysis of micro RNAs in camel milk exosomes.","authors":"Rinile Wu, Caifeng Yue, Yina Xie, Yuerong Fu, Xin Yu, Zhuoyuan Li, Bin Yang","doi":"10.1556/004.2023.00869","DOIUrl":"https://doi.org/10.1556/004.2023.00869","url":null,"abstract":"In order to study the species and functions of micro (mi)RNAs in the exosomes of camel milk, non-coding small (s)RNAs were sequenced and identified by Illumina sequencing technology, and the miRNA fraction was analysed by bioinformatics. After quality control, the average length of sRNA of camel milk exosomes was 18-24 nucleotides. A total of 2,659 miRNAs were identified, including 2,458 known, and 201 new miRNAs. Among the known miRNAs, miR-148a and let-7i had the highest expression levels. The results of gene ontology enrichment analysis indicated that the target genes of camel milk exosome miRNAs were involved in multicellular organismal, catabolic and other biological processes. They play role in the extracellular region, in the cytoskeleton and other cell components, in protein binding, but also have structural molecule activity and other molecular functions. According to the results of the Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis, the target genes of camel milk exosome miRNAs are involved in Alzheimer's disease, non-alcoholic fatty liver disease, Staphylococcus aureus infection and other pathological pathways. We speculate that the reported beneficial effect of camel milk in various pathologic conditions may be closely related to the regulatory function of the exosomal miRNAs exerted on target genes of the diseases.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41097650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multilocus sequence analysis (MLSA) of a Nocardia cyriacigeorgica strain causing severe bovine mastitis in Bosnia and Herzegovina. 波斯尼亚和黑塞哥维那一株引起严重乳腺炎的cyriacigeorgica诺卡氏菌菌株的多基因座序列分析（MLSA）。

IF 0.9 4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-09-07 Print Date: 2023-10-17 DOI: 10.1556/004.2023.00893

Oliver Stevanović, Dubravka Milanov, Isidora Prošić, Vladimir Gajdov, Drago Nedić, Željko Sladojević, Andrea Radalj

{"title":"Multilocus sequence analysis (MLSA) of a Nocardia cyriacigeorgica strain causing severe bovine mastitis in Bosnia and Herzegovina.","authors":"Oliver Stevanović, Dubravka Milanov, Isidora Prošić, Vladimir Gajdov, Drago Nedić, Željko Sladojević, Andrea Radalj","doi":"10.1556/004.2023.00893","DOIUrl":"10.1556/004.2023.00893","url":null,"abstract":"Nocardia cyriacigeorgica is a well-known agent of human nocardiosis and is considered an emerging pathogen, however, its identification to the species level is complex for many clinical laboratories. Available data on the clinical significance of N. cyriacigeorgica in veterinary medicine are sparse and mainly concern isolated reports of pyogranulomatous lesions in domestic animals. We report a case of severe bovine mastitis caused by N. cyriacigeorgica that did not respond to conventional antimicrobial therapy in a small holding in Bosnia and Herzegovina. After isolation of the pathogen, further identification by routine microbiological methods was not possible. Susceptibility to antimicrobials was tested using the disc diffusion method according to published recommendations. The sample was also tested by MALDI-ToF MS with inconclusive results. In addition, 16S rRNA sequence analysis, verified by multilocus sequence analysis (MLSA) using the gyrB, 16S rRNA, secA1, and hsp65 sequences, confirmed the species N. cyriacigeorgica. To our knowledge, this is the first report of isolation of N. cyriacigeorgica from a clinical case of bovine mastitis in a European dairy farm and the first MLSA method approach to distinguish a Nocardia spp. strain isolated from animals.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"65-70"},"PeriodicalIF":0.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10178902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plasma melatonin concentration during the early post-partum period in Thoroughbred mares and their foals. 纯种母马及其小马驹产后早期的血浆褪黑素浓度。

IF 0.9 4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-09-06 Print Date: 2023-10-17 DOI: 10.1556/004.2023.00883

András Gáspárdy, Gemma Gallagher, Boróka Bartha, Sándor Cseh, Sándor György Fekete, Bence Somoskői

{"title":"Plasma melatonin concentration during the early post-partum period in Thoroughbred mares and their foals.","authors":"András Gáspárdy, Gemma Gallagher, Boróka Bartha, Sándor Cseh, Sándor György Fekete, Bence Somoskői","doi":"10.1556/004.2023.00883","DOIUrl":"10.1556/004.2023.00883","url":null,"abstract":"The authors aimed to determine the plasma melatonin concentration in mares and their new-born foals in the early post-partum period. Blood samples were collected from the jugular vein of 53 mare-foal pairs within twelve hours after parturition. Plasma melatonin levels were measured by ELISA. The melatonin concentration, adjusted for the moment of parturition using a generalised linear model, was 34.58 pg mL-1 in mares. It was significantly lower (27.63 pg mL-1) in the new-born foals. However, the melatonin concentration declined differently by the end of the twelve hours, it decreased less in the offspring than in the mothers. An artificial light supplementation at the end of gestation reduced the melatonin concentration both in mares and their foals by about 10 pg mL-1, compared to the controls. An elevated melatonin production may be related to preparation of mares for parturition and ensures the chances of survival of offspring, therefore the melatonin may reach its peak at the moment of foaling regardless of its actual time. The effect of low melatonin concentration in new-born foals might be associated with the foal's health and subsequent performance. The need to monitor the melatonin concentration in the offspring justifies further studies.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"119-127"},"PeriodicalIF":0.9,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10182199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of pituitary adenylate cyclase-activating polypeptide supplementation, applied during or after vitrification on mouse embryo. 玻璃化过程中或玻璃化后补充垂体腺苷酸环化酶激活多肽对小鼠胚胎的影响。

IF 0.9 4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-09-06 Print Date: 2023-10-17 DOI: 10.1556/004.2023.00903

Dóra Török, Bence Somoskői, Lilla Bordás, Dóra Reglődi, Sándor Cseh

{"title":"Effect of pituitary adenylate cyclase-activating polypeptide supplementation, applied during or after vitrification on mouse embryo.","authors":"Dóra Török, Bence Somoskői, Lilla Bordás, Dóra Reglődi, Sándor Cseh","doi":"10.1556/004.2023.00903","DOIUrl":"10.1556/004.2023.00903","url":null,"abstract":"Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide with widespread occurrence and diverse functions. It occurs in high levels in the gonads suggesting a potential central role in reproduction. The aim of our study was to assess the effect of PACAP treatment during embryo vitrification on the developmental rate and the expression of the heparin-binding EGF-like growth factor gene (Hbegf). Mouse embryos, obtained from superovulated females were allocated into the four treatment groups. In EM1 and EM2, the embryos were prepared for vitrification in an Equilibration Solution that was supplemented with 1 or 2 μM PACAP1-38, respectively. The embyos in groups CM1 and CM2 were not treated prior to vitrification but were cultured in a medium supplemented with 1 or 2 μM PACAP1-38 after thawing. The Vitrified Control group consisted of embryos vitrified and thawed then cultured without PACAP1-38 treatment. A non-vitrified, non-treated Fresh Control group was also used. After 24 h of culture, the developmental rate of the embryos, as well as the relative expression level of the Hbegf gene, as determined by qPCR, were compared among groups. Higher developmental rate and Hbegf gene expression level were found in the embryos treated with a higher concentration of PACAP. These results indicate that PACAP treatment has a beneficial effect on the survival and development of vitrified/thawed mouse embryos.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"112-118"},"PeriodicalIF":0.9,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10183901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism. 慢性甲状腺功能亢进失控引起的肥厚型心肌病表型引起的猫心力衰竭。

IF 0.9 4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-07-31 Print Date: 2023-10-17 DOI: 10.1556/004.2023.00815

Hayoon Lee, Dohee Lee, Jooyoung Park, Taesik Yun, Yoonhoi Koo, Yeon Chae, Byeong-Teck Kang, Mhan-Pyo Yang, Hakhyun Kim

{"title":"Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism.","authors":"Hayoon Lee, Dohee Lee, Jooyoung Park, Taesik Yun, Yoonhoi Koo, Yeon Chae, Byeong-Teck Kang, Mhan-Pyo Yang, Hakhyun Kim","doi":"10.1556/004.2023.00815","DOIUrl":"10.1556/004.2023.00815","url":null,"abstract":"A 16-year-old castrated male Persian cat was presented with weight loss, anorexia and dyspnoea. Tachycardia and tachypnoea were observed upon presentation. The cat was previously diagnosed with hyperthyroidism and left ventricular hypertrophy and received methimazole, but was subsequently not followed up and treated appropriately. Thoracic radiography revealed mild pleural effusion, interstitial lung pattern, moderate cardiomegaly and moderate-to-severe dilation of the pulmonary artery and pulmonary vein. On echocardiography, the left ventricular hypertrophy, identified earlier, shoed partial regression. Therefore, the previous myocardial hypertrophy was diagnosed as a hypertrophic cardiomyopathy phenotype related to hyperthyroidism. ST-segment elevation was identified on electrocardiography, and the thyroid profile examination revealed increased total thyroxine and free thyroxine and decreased thyroid-stimulating hormone levels, suggesting myocardial injury and uncontrolled hyperthyroidism, respectively. In addition, normal N-terminal pro-B-type natriuretic peptide and high cardiac troponin I levels were found. Based on these findings, the observed congestive heart failure was considered as a sequel of myocardial injury caused by uncontrolled hyperthyroidism. Clinical signs resolved after intravenous administration of furosemide and butorphanol, oxygen supply and thoracocentesis. Furosemide and pimobendan were additionally administered, and the cat was discharged. This case demonstrates that myocardial damage due to chronic uncontrolled hyperthyroidism may cause heart failure in cats.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"96-100"},"PeriodicalIF":0.9,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9922472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital cerebral and cerebellar anomalies in relation to bovine viral diarrhoea virus and Akabane virus in newborn calves. 新生牛犊先天性脑和小脑异常与牛病毒性腹泻病毒和阿卡巴纳病毒的关系。

IF 0.9 4区农林科学

Acta veterinaria Hungarica Pub Date : 2023-06-20 DOI: 10.1556/004.2023.00764

Diba Golchin, Farhang Sasani, Farhad Moosakhani, Arya Badiei, Mohsen Zafari, Minoo Partovi Nasr

{"title":"Congenital cerebral and cerebellar anomalies in relation to bovine viral diarrhoea virus and Akabane virus in newborn calves.","authors":"Diba Golchin, Farhang Sasani, Farhad Moosakhani, Arya Badiei, Mohsen Zafari, Minoo Partovi Nasr","doi":"10.1556/004.2023.00764","DOIUrl":"https://doi.org/10.1556/004.2023.00764","url":null,"abstract":"Congenital malformations occur sporadically in cattle; however, congenital structural and functional disorders of the nervous system are rather common in ruminants. Among the numerous causes of congenital nervous system defects, infectious agents are highlighted in this paper. Virus-induced congenital malformations are well known, among which those caused by bovine viral diarrhoea virus (BVDV), Akabane virus (AKAV), Schmallenberg virus (SBV), Bluetongue virus (BTV), and Aino virus (AV) are the most studied. In this study, we specify and categorise macroscopic and histopathological lesions in the brain of 42 newborn calves suffering from severe neurologic signs and diagnosed with BVDV and AKAV infection. Following a complete necropsy, specimens were collected from the brains to track the presence of BVDV, AKAV and SBV utilising reverse transcription polymerase chain reaction. Of the 42 examined calves, 21 were BVDV positive and 6 were AKAV positive, while 15 brains were negative for the studied agents. Regardless of the aetiology, cerebellar hypoplasia, hydranencephaly, hydrocephalus, porencephaly, and microencephaly were detected. Cerebellar hypoplasia was the most common lesion seen in both BVDV-positive and AKAV-positive cases. Virus-induced necrosis of the germinative cells of the external granular layer of cerebellum, as well as vascular damages, are believed to be the underlying causes of cerebellar hypoplasia. BVDV was the most important aetiological agent of such cases in this study.","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":"71 1","pages":"34-40"},"PeriodicalIF":0.9,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9696793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1