Acta veterinaria Hungarica最新文献

{"title":"First detection of myxomatosis in European brown hares (Lepus europaeus) in West-Hungary.","authors":"János Gál, Sándor Faragó, Gáspár Keszthelyi, Zoltán Vincze, Yaoqin Shen, Míra Mándoki, Lilla Dénes, Miklós Süth, Péter Sótonyi","doi":"10.1556/004.2025.01264","DOIUrl":"10.1556/004.2025.01264","url":null,"abstract":"<p><p>The authors were the first to identify myxomatosis in brown hares (Lepus europaeus) in a hunting area in western Hungary. During the necropsy of brown hares, dermatitis accompanied by multiplex pustule formation and keratinisation disorders were observed primarily on the head, eyelids, ears and skin around the mouth. Subacute keratoconjunctivitis and catarrhal-purulent rhinitis were confirmed during the autopsy. In addition, multiplex, nodular pneumonia and hemorrhages in the intertubular space of the kidneys, as well as tubulonephrosis, were also observed. Hyperkeratosis and parakeratosis were seen in the epithelium, along with the appearance of myxoma cells and heterophil granulocyte infiltration. The lesions found in the hares, such as significant swelling of the eyelids and keratoconjunctivitis, significantly impaired the animals' orientation. The clinical picture observed by the authors was preceded by infection with Leporipoxvirus myxoma, a member of the Leporipoxvirus genus. This virus strain belonging to the same phylogenetic group as the classic Lausanne, Cornwall, Sussex, and Munich strains previously described in rabbits.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"26-33"},"PeriodicalIF":0.8,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145538519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possible effect of artificial insemination and multiple ovulation embryo transfer on the health and survival of Holstein-Friesian calves.","authors":"Eszter Tóth, József Rátky, János Posta, Renáta Knop","doi":"10.1556/004.2025.01183","DOIUrl":"10.1556/004.2025.01183","url":null,"abstract":"<p><p>Reproductive technologies like artificial insemination (AI) and multiple-ovulation embryo transfer (MOET) are extensively used in cattle breeding, but their effects on the health and growth of calves remain unclear. This study evaluated the effects of AI and MOET on morbidity, survival and weaning weight in Holstein-Friesian heifer calves. A total of 366 calves (AI: n = 314; MOET: n = 52) were followed for 91 days from birth. Morbidity was classified based on the incidence and severity of diarrhoeal and respiratory disease. Weaning weights were contrasted with disease incidence. Statistical analyses included chi-square tests for categorical data and ANOVA for continuous data (P < 0.05). Survival and overall morbidity rates were not influenced greatly by reproductive technology. The prevalence of diarrhoeal disease was similar for MOET and AI groups (P > 0.05), but respiratory disease was greater and more severe in MOET calves (P < 0.05). Morbidity negatively impacted weaning weight in AI calves (P < 0.05) but had no significant impact on MOET calves. Season and colostrum quality significantly influenced survival, with greater survival rates noted for autumn-born calves and calves that received high-quality colostrum (>25% IgG) (P < 0.05). While reproductive technology had little effect on survival, MOET calves showed a heightened susceptibility to respiratory illnesses, highlighting the importance of targeted health management.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"277-286"},"PeriodicalIF":0.8,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145450489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saliva as alternative diagnostic biofluid for non-invasive health and disease appraisal in domestic and wild animals: A review of salivary biomarkers and sialochemistry.","authors":"Mayur M Jadav, Vivek Joshi","doi":"10.1556/004.2025.01192","DOIUrl":"10.1556/004.2025.01192","url":null,"abstract":"<p><p>Saliva is a readily available biofluid that contains a wide variety of biomarkers similar to blood. In this context, sialochemistry offers a new non-invasive and animal-friendly diagnostic technique, which may ultimately replace traditional invasive blood-based testing. Saliva presents distinct advantages over blood as it can be collected by non-specialist personnel with minimal stress to animals and sialochemistry is a cost-effective and easily replicable technique. The present article highlights the emerging paradigm of salivary biomarkers and diagnostic feasibility of sialochemistry in veterinary medicine. The current state of knowledge of salivary biomarkers of infectious and non-infectious diseases with diagnostic value in domestic and wild/zoo animals is summarised. Evidence illustrated that salivary biomarkers are linked to animal diseases, immune status, stress and systemic inflammation in the body. The presence of economically important pathogens and antibodies in saliva makes it a profoundly useful specimen for early screening and redressal of disease outbreak. Diagnostically, zoo veterinarians find salivary biomarkers handy for health surveillance purposes. Saliva is anticipated to serve as an alternative diagnostic specimen to blood. Future research is sought to validate novel salivary proteins as disease biomarkers and eventually, formulate saliva-based point-of-care assays.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"264-276"},"PeriodicalIF":0.8,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145436723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of primary uterine inertia on blood gases and acid-base parameters in a chronically cannulated bovine foetus during calving: A case report.","authors":"Ottó Szenci, Gijsbert Cornelis Van Der Weyden, Lea Lénárt, Marcel Antoine Marie Taverne","doi":"10.1556/004.2025.01159","DOIUrl":"10.1556/004.2025.01159","url":null,"abstract":"<p><p>Foetal arterial catheterisation is an effective tool for conducting longitudinal in vivo studies on foetal blood gases and acid-base fluctuations. These surgical techniques have made obtaining daily blood samples under aseptic conditions feasible to determine arterial and/or venous blood gases and acid-base parameters. The present study aimed to elucidate the changes in arterial blood gases and acid-base variables obtained from a catheterised foetus during the final days preceding and during the calving process. It focused specifically on a case of primary uterine inertia and two typical cases. The average gestation length observed in three cows with chronically catheterised foetuses was 285 ± 10 days. The arterial and venous acid-base variables recorded in the three catheterised dams remained stable throughout the late gestation and calving phases. Similarly, these acid-base parameters remained consistent until the last 35 min before birth for Foetus B and until the last 22 min for Foetus A. At these points, physiological acidosis emerged in Foetus B, while moderate respiratory and metabolic acidosis developed in Foetus A until birth. In contrast, Foetus C experienced a gradual development of severe respiratory and metabolic acidosis during the last 8 h before birth, with continued deterioration observed in the 37 min leading up to birth. While there were no significant differences in the duration of electromyography (EMG) activities among the cows, a notable increase was recorded at 7 h before birth in Cow A and 15 h before birth in Cow B. Conversely, Cow C exhibited elevated EMG activity (>1,500 s*h-1) 8 h before birth. Additionally, during the last 3 h leading to birth in Cow C, a discernible reduction was noted compared to the other two cows. This case study highlights the importance of performing an exploratory vaginal examination when no clear clinical signs of stage one or any suspicious clinical symptoms, such as bloody vaginal mucus, are observed during the expected last day of gestation to prevent foetal mortality during calving.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"287-293"},"PeriodicalIF":0.8,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145421001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reference values of intraocular pressure in captive bred European brown hares (Lepus europaeus).","authors":"János Gál, Judit Sebesztha-Kojer, Endre Sós, Bence Sebesztha, Márton Hoitsy, Anna Linda Nógrádi, Árisz Ziszisz","doi":"10.1556/004.2025.01179","DOIUrl":"10.1556/004.2025.01179","url":null,"abstract":"<p><p>In a preliminary survey study, the authors measured intraocular pressure in the right and left eye of 63 (32 females and 31 bucks) 3-8 month old, clinically healthy European brown hares (Lepus europaeus, Pallas, 1778). The mean intraocular pressure was 25.35 millimeters of mercury (mmHg) (n = 63), 25.4 mmHg for bucks and 25.3 mmHg for females. The average standard deviation was 4.86. The difference in intraocular pressure (IOP) between rabbits aged 3-5 months and 6-8 months was not significant, nor was the difference between females and bucks.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"207-211"},"PeriodicalIF":0.8,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145407810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The accuracy and precision of a portable refractometer in measuring the plasma total protein concentrations in Nigerian trade cattle.","authors":"Onyinyechukwu A Agina, Arinzechukwu S Ezema, John C Umezinwa","doi":"10.1556/004.2025.01166","DOIUrl":"10.1556/004.2025.01166","url":null,"abstract":"<p><p>This study aimed to obtain the accuracy and precision of a refractometer compared to the biuret methods in measuring plasma total protein in cattle. The total protein concentrations were determined in 131 cattle plasma samples using the biuret and refractometry methods. Paired samples t-test values, Passing-Bablok regression equations and Bland-Altman plots were generated following statistical analysis of the total protein values. Statistical analysis revealed that the refractometer produced a significantly (P < 0.05) higher mean total protein value than the biuret method. The statistical precision and accuracy were 97.16% and 97.52%, respectively. The concordance correlation coefficient test (0.9476) showed a strong linear relationship between the total protein values obtained by the two methods and a moderate agreement between the two methods of total protein determination, but based on the Passing- Bablok analysis, both methods can be used independently. Furthermore, the CUSUM test for linearity with a large P of 0.10 also indicated a linear relationship between the two methods. The Bland-Altman plot indicated an analytical error of 3.0% which is clinically insignificant. The refractometry method was accurate with high precision for the determination of plasma total protein concentrations in cattle. It is portable, accurate and cost-effective.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"222-227"},"PeriodicalIF":0.8,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the efficacy of intra-articular botulinum toxin type A application in the treatment of experimentally induced osteoarthritis in rats.","authors":"Tolga Meriç Dümbek, Zeynep Bozkan Ünal","doi":"10.1556/004.2025.01152","DOIUrl":"10.1556/004.2025.01152","url":null,"abstract":"<p><p>This study aimed to evaluate the effectiveness of botulinum toxin type A in rat model of experimentally induced osteoarthritis. The experiment was conducted on 30 male Sprague-Dawley rats. Osteoarthritis was induced via intra-articular injection of MIA at a dose of 3 mg per rat. The efficacy of intra-articular injections of 10 U BoNT-A and 20 U BoNT-A was assessed through body weight monitoring, knee circumference measurements, leg posture scoring, as well as X-ray, µCT and histopathological examination. Data were analysed using repeated measures ANOVA, generalised linear model, Kruskal-Wallis test, independent samples T test and Mann-Whitney U test. BoNT-A administration led to a significant decrease in body weight and a significant increase in lameness scoring. No significant change was observed in knee circumference measurements by the end of the study. While X-ray evaluations showed no significant differences, micro-CT analyses revealed statistically significant changes. In conclusion, BoNT-A produced statistically significant yet clinically negligible effects on pain and bone parameters. Additionally, higher doses (20U) of BoNT-A were associated with adverse effects.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"251-263"},"PeriodicalIF":0.8,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological and molecular effects of buckwheat-enriched diets in male rats with a focus on reproductive tissue.","authors":"Elif Erbaş, Gamze Uçak, Seviye Olgun, Sıla Ektaş Kalaycı, Halit İmi̇k, Adem Kara","doi":"10.1556/004.2025.01203","DOIUrl":"10.1556/004.2025.01203","url":null,"abstract":"<p><p>In this study, the effect of dietary buckwheat on rat testicular tissue was investigated. In the study, 28 male Sprague Dawley rats were used. The rats were randomly divided into four equal groups. The Control Group was fed with a diet containing 36% wheat, Group-1 with 12% buckwheat and 24% wheat, Group-2 with 24% buckwheat and 12% wheat and Group-3 with 36% buckwheat. At the end of the study, the expression levels of Bcl-2, Caspase-3, P38-MAPK, STAT3, JAK2 and PI3K genes were analyzed by Western blot analysis. As the proportion of buckwheat in the diet increased, caspase-3 gene expression increased, but the expression of other genes decreased. In testicular histology, the structure of the Control Group and Group-1 was preserved, while deterioration was observed in the other two groups. Since this damage would also affect spermatogenesis and spermatozoa in the epididymis, subsequent spermatologic analysis showed a significant decrease in semen quality in Group-3. It was concluded that 12% buckwheat supplementation positively affected the testicular structure and semen quality of rats, while 36% buckwheat supplementation negatively affected the testicular structure and semen quality.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"212-221"},"PeriodicalIF":0.8,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection by SARS-CoV-2 in a rescued serval (Leptailurus serval, Schreber, 1776).","authors":"Endre Sós, Tibor Papp, Viktória Sós-Koroknai, Márton Hoitsy, Anna Szilasi, Nándor Balogh, Miklós Marosán, János Gál","doi":"10.1556/004.2025.01178","DOIUrl":"https://doi.org/10.1556/004.2025.01178","url":null,"abstract":"<p><p>In late November 2021, a male serval (Leptailurus serval) which had escaped from an unknown holding facility was observed in the Bükk Mountains of Northern Hungary. A few days were needed to capture the animal with a live trap, after which it was transported to a national Rescue Centre at the Budapest Zoo and Botanical Garden. The exact origin of the specimen was never identified and apart from being emaciated, it seemed only to be stressed and weakened by the cold weather and starvation. Contrary to the initial fair prognosis, 2.5 days after admittance, the animal rapidly developed pronounced respiratory and central nervous system signs and despite intensive treatment died within a few hours. The subsequent diagnostic investigation revealed that the cause of death was SARS-CoV-2 infection. These diagnostic steps excluded other possible, lethal felid pathogens as causative agents and confirmed that the disease process was attributed to this virus.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Report of a feline Cryptococcus neoformans infection in Hungary.","authors":"Zsombor Tóth, Márton Márialigeti, Zoltán Lajos, Noémi Tarpataki","doi":"10.1556/004.2025.01187","DOIUrl":"10.1556/004.2025.01187","url":null,"abstract":"<p><p>Cryptococcosis is a globally occurring fungal disease that affects both humans and animals. It is the most common systemic mycosis in cats, primarily documented through case reports and retrospective studies. In feline cases, clinical symptoms typically begin with skin lesions appearing in the nasal and frontal regions, as observed in the case presented here. This case report details a 13-year-old European shorthair cat that presented with a 3-month history of progressive naso-ocular lesions and weight loss. The cat was likely infected through cat scratches, leading to contamination with encapsulated yeast cells, which resulted in localized skin lesions. Skin scrape cytology of the lesions showed many macrophages with numerous extra and intracytoplasmic organisms compatible with Cryptococcus species. Histopathological examination revealed pyogranulomatous inflammation with encapsulated yeasts. Latex cryptococcal antigen agglutination test on serum was positive. Fungal culture identified Cryptococcus neoformans. Unfortunately, shortly after the initiation of targeted treatment, the cat passed away. The authors provide a comprehensive overview of this cryptococcosis case. Cryptococcosis is an underdiagnosed disease and its early detection can be challenging due to nonspecific symptoms. Early initiation of targeted antifungal therapy significantly increases the chances of recovery.</p>","PeriodicalId":7247,"journal":{"name":"Acta veterinaria Hungarica","volume":" ","pages":"237-242"},"PeriodicalIF":0.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}