Ingrid Raquel Dos Santos Araújo, Emilson Lima de Brito, Ubiratan Pereira de Melo, Amanda Louíse Bittencourt Mariz, Mauricio Teixeira Cavalheiro, Cintia Ferreira, Leonardo Fiusa de Morais, Renato Fernandes de Souza
{"title":"Knowledge levels regarding antibiotics and their use among horse owners in the State of Rio Grande do Norte, Brazil.","authors":"Ingrid Raquel Dos Santos Araújo, Emilson Lima de Brito, Ubiratan Pereira de Melo, Amanda Louíse Bittencourt Mariz, Mauricio Teixeira Cavalheiro, Cintia Ferreira, Leonardo Fiusa de Morais, Renato Fernandes de Souza","doi":"10.29374/2527-2179.bjvm000425","DOIUrl":"10.29374/2527-2179.bjvm000425","url":null,"abstract":"<p><p>This study aimed to evaluate the use of antimicrobials in horses, focusing on administration practices, adherence to veterinary prescriptions, and the impact on the development of antimicrobial resistance. The research was based on a questionnaire completed by 220 horse owners in the State of Rio Grande do Norte, Brazil. The data collected covered aspects including antibiotic use, prescription sources, the performance of culture and susceptibility tests, and the disposal of veterinary drug waste. The results indicated that 98.63% of horse owners administered antibiotics mainly to treat respiratory diseases. However, adherence to veterinary prescriptions was limited, with only 47.72% of horse owners correctly following the guidelines regarding dosage and treatment duration. Additionally, 68.18% of horse owners did not perform culture tests prior to antimicrobial treatment, and many obtained antibiotic recommendations from non-professional sources, such as friends or staff at veterinary product stores. These findings suggest that inappropriate antibiotic use practices, such as empirical and non-prescribed use, are contributing to the rise in antimicrobial resistance. The need for educational campaigns targeting horse owners is critical to raise awareness about the importance of rational antimicrobial use, risks of indiscriminate use, and necessity of performing laboratory tests to select appropriate treatment options.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e000425"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective five-year study of equine casuistry in a Colombian perinatology center.","authors":"Melissa Tovar Parra, Martha Susana Franco Ayala","doi":"10.29374/2527-2179.bjvm005824","DOIUrl":"10.29374/2527-2179.bjvm005824","url":null,"abstract":"<p><p>A retrospective study was conducted at the Foal Care Equine Perinatology Center in Colombia from October 2017 to May 2023. The goal was to analyze the most frequent pathologies, as well as assess the sexes, ages, and breeds of the patients, with an emphasis on the perinatal population. Out of 945 clinical histories, 776 pertained to perinatology. Survival rates were calculated, and a descriptive analysis was performed. The overall survival rate for neonates was 73.6%, with females constituting 57% of the neonatal patients. The most prevalent breed among mares and neonates was the Creole Colombian Horse. Neonatal maladjustment accounted for 39.34% of the neonatal cases, and regarding the affected systems, there was a common multisystemic presentation (71.40%). Of the 341 foals admitted for neonatal adaptation, 72 were clones (with a survival rate of 76.39%), while 269 were non-clones (with a survival rate of 72.49%). A total of 202 mares (88.98%) were hospitalized for pregnancy monitoring, while 25 mares (11.02%) were brought to the perinatology center to treat dystocia or other reproductive pathologies. The most frequent diagnosis among mares was placentitis (73.68%). This study noted an increase in survival rates over time, which was associated with improvements in protocols and the acquisition of new medical equipment. The survival rates observed in this study are consistent with those reported in previous research. The collected data indicate that foaling occurs year-round in Colombia since the country experiences no distinct seasons. Studies with larger sample sizes are suggested, as well as periodical analysis of casuistry in the equine neonatology field, to improve the clinical management of patients and enhance productivity in the horse breeding industry.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e005824"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pleomorphic lobular carcinoma in a cat: Clinical, histopathological, and immunohistochemical characterization.","authors":"Júlia Gabriela Wronski, Maíra Meira Nunes, Érica Almeida Viscone, Evelyn Ane Oliveira, Mariana da Silva Figueiredo, Geovanni Dantas Cassali, Karen Yumi Ribeiro Nakagaki","doi":"10.29374/2527-2179.bjvm001725","DOIUrl":"10.29374/2527-2179.bjvm001725","url":null,"abstract":"<p><p>Mammary carcinomas in cats are highly aggressive neoplasms, often with the development of metastasis. Pleomorphic lobular carcinoma, on the other hand, is an invasive carcinoma with aggressive behavior, rarely diagnosed in humans and dogs. This report describes a case of pleomorphic lobular carcinoma in cats. The histopathological and immunohistochemical features of the neoplasm in this species were characterized. The neoplasm was diagnosed in a 10-year-old cat, with regional lymph node involvement at the time of diagnosis, but without systemic signs based on imaging tests performed prior to mastectomy. However, respiratory clinical signs developed approximately 40 days after surgery, accompanied by neoplastic pleural effusion, and the patient was euthanized due to the onset of neurological signs and poor prognosis. Although uncommon, pleomorphic lobular carcinoma is a neoplasm that can affect cats, and given its poor prognosis, it is important for oncologists and pathologists to be familiar with this entity.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e001725"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucas de Souza Viana, Diego Neves Vianna, Camila Cristina Rio Preto Martins de Sousa, Suzana de Souza Lima, Bruno Alberigi
{"title":"Evaluation of the lacrimal and nasolacrimal system in dogs treated at a veterinary ophthalmology service.","authors":"Lucas de Souza Viana, Diego Neves Vianna, Camila Cristina Rio Preto Martins de Sousa, Suzana de Souza Lima, Bruno Alberigi","doi":"10.29374/2527-2179.bjvm001125","DOIUrl":"10.29374/2527-2179.bjvm001125","url":null,"abstract":"<p><p>In routine veterinary medicine, the lacrimal and nasolacrimal systems are associated with several ophthalmopathies. Understanding its physiology and improving specific diagnostic tests will help establish an assertive approach and avoid lacrimal and nasolacrimal disorders that cause damage to the ocular surface. This prospective study was conducted on 43 dogs treated at the Veterinary Ophthalmology Service and approved by the Ethics Committee for the Use of Animals under protocol number 5154141022. The study's objective of this study was to evaluate lacrimal and nasolacrimal system findings in dogs treated byat an ophthalmology service, determine the frequency of lacrimal and nasolacrimal system disorders, and correlate the diagnosed changes with the patient's main complaint. All dogs underwent a complete ophthalmic examination, emphasizing the lacrimal and nasolacrimal tests: the Schirmer tear test, tear film break-up test, tear crystallization test, and Jones test. The findings of these tests correlated with those of the ocular surface and the general condition of the dogs. Statistical analyses were performed using the Shapiro-Wilk test, Pearson's chi-square test, and Student's <i>t</i> test. The Student's <i>t</i> test revealed that dogs with normal tear crystallization test scores had a significantly higher score (25.5 ± 4.94) than dogs with altered tear crystallization test scores (15.35 ± 6.64) (<i>t</i> (40) = 2.121, <i>p</i> = 0.004). Our findings suggest that quantitative and qualitative tear tests should be performed together and their interpretation depends on several factors, including ocular and systemic disorders.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e001125"},"PeriodicalIF":0.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
André Gustavo Alves Holanda, Patrick Antônio Sonaglio Civa, Carlos Eduardo Fonseca-Alves, Denner Santos Dos Anjos
{"title":"Safety and feasibility of lapatinib for the treatment of a EGFR1/HER-2-positive advanced gastrointestinal stromal tumor in a cat.","authors":"André Gustavo Alves Holanda, Patrick Antônio Sonaglio Civa, Carlos Eduardo Fonseca-Alves, Denner Santos Dos Anjos","doi":"10.29374/2527-2179.bjvm001825","DOIUrl":"10.29374/2527-2179.bjvm001825","url":null,"abstract":"<p><p>Gastrointestinal stromal tumors (GISTs) are uncommon mesenchymal tumors in cats that originate from interstitial cells of Cajal (ICC). ICCs are mesenchymal cells found within the muscle layers of the alimentary tract that facilitate communication between the autonomic nervous system and smooth muscles. In this case, lapatinib, a tyrosine kinase inhibitor (TKI) that targets EGFR1 and HER2, was used as part of precision therapy for metastatic GIST in an 8-year-old, 2.7 kg, spayed, female mixed-breed cat, guided by the high expression of these receptors in the tumor. The treatment resulted in partial remission of liver metastases, with a progression-free survival of 171 days and an overall survival of 192 days after starting lapatinib. Lapatinib was well tolerated, with minimal adverse gastrointestinal effects. These findings highlight the potential role of molecular profiling in guiding targeted therapy for feline GISTs and suggest that lapatinib may be a viable treatment option for EGFR1/HER2-positive tumors. Further studies are needed to evaluate the efficacy and safety of TKIs in veterinary oncology, as well as their impact on long-term survival and quality of life in feline patients with GISTs.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e001825"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Paula da Costa Rodrigues, Ricardo Pozzobon, Grasiela De Bastiani, Flávio Desessards De La Côrte, Marcos da Silva Azevedo
{"title":"Objective lameness assessment of 235 horses undergoing lameness examination in Brazil: A retrospective study.","authors":"Ana Paula da Costa Rodrigues, Ricardo Pozzobon, Grasiela De Bastiani, Flávio Desessards De La Côrte, Marcos da Silva Azevedo","doi":"10.29374/2527-2179.bjvm008224","DOIUrl":"10.29374/2527-2179.bjvm008224","url":null,"abstract":"<p><p>Lameness, which arises from functional or structural changes in the limbs or axial skeleton, causes asymmetry in the movement of the equine head and/or pelvis. This study aimed to investigate the lameness patterns of horses that underwent lameness examination or monitoring during the years 2016 to 2020. This retrospective study used data from the lameness examination, evaluated using an objective assessment with body-mounted wireless inertial sensors. The lameness examination comprised clinical history, static inspection, palpation, gait evaluation (for which the animals were equipped with a wireless inertial sensor system), flexion tests, lunging examination, diagnostic anesthetic blocks, and imaging examinations. Based on objective assessment data, the condition of lameness, limb with primary lameness, type of lameness, intensity, and location of lameness were determined. Of the 235 animals included in this study, 93,6% presented lameness. Of the animals with lameness, 59,5% had forelimb lameness and 40,5% had hindlimb lameness. The most frequent lameness condition was primary lameness in one limb and secondary lameness in the other. Impact lameness was the most frequent type in both the forelimb and hindlimb. Moderate-to-severe lameness was the most frequent level of intensity. Regarding the lameness location, in the forelimb, the distal region was the most affected, while in the hindlimb, the proximal lower region was the most affected. We conclude that forelimb lameness is more frequent in horses examined in southern Brazil and mainly affects the distal limb region.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e008224"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luiz Felipe Crispim Lourenço, Frederico Monfardini, Carlos Eduardo Nogueira Martins, Ricardo Evandro Mendes
{"title":"Kernel Density Estimation (KDE) as a tool to enhance bovine tuberculosis surveillance in Santa Catarina, Brazil.","authors":"Luiz Felipe Crispim Lourenço, Frederico Monfardini, Carlos Eduardo Nogueira Martins, Ricardo Evandro Mendes","doi":"10.29374/2527-2179.bjvm001025","DOIUrl":"https://doi.org/10.29374/2527-2179.bjvm001025","url":null,"abstract":"<p><p>In areas with low bovine tuberculosis (bTB) prevalence, such as Santa Catarina state, Brazil, effective surveillance is essential for disease eradication. Current strategies may miss high-risk farms by inadequately considering spatial risk factors. This study used Kernel Density Estimation (KDE) to analyze spatial risk patterns in Santa Catarina, Brazil, leveraging the official veterinary service's (CIDASC's Sigen+ database) farm data, testing history, and animal movement records. Results revealed that while existing surveillance targets many high-risk areas, some remain unmonitored. Practices such as on-farm slaughter and insufficient movement testing create vulnerabilities that can hinder bTB detection. Integrating KDE-derived risk maps into the current surveillance efforts can improve targeted resource allocation and disease control. This study demonstrated the value of spatial risk analysis for enhancing bTB surveillance in Santa Catarina state, offering a strategic tool to support CIDASC's eradication efforts and serving as a model for other regions seeking to strengthen their surveillance programs.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e001025"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitor Luz Carvalho, Daniel Araújo Viana, Alexsandro Antonio Portilho Damasceno, Maria Vivina Barros Monteiro, Frederico Ozanan Barros Monteiro
{"title":"Capture myopathy in a wild Clymene dolphin (<i>Stenella clymene</i>) stranded alive on the coast of Ceará State, Brazil.","authors":"Vitor Luz Carvalho, Daniel Araújo Viana, Alexsandro Antonio Portilho Damasceno, Maria Vivina Barros Monteiro, Frederico Ozanan Barros Monteiro","doi":"10.29374/2527-2179.bjvm00625","DOIUrl":"https://doi.org/10.29374/2527-2179.bjvm00625","url":null,"abstract":"<p><p>Stranded cetaceans face critical illnesses and often present with multiple co-morbidities, which are further exacerbated by the stress induced by stranding events and interactions with humans. Capture myopathy (CM) is a common condition in dolphins and other wildlife subjected to extreme stress during capture, handling, or transportation. This condition is particularly problematic in highly sensitive species such as dolphins, whose intense physiological response to stress can lead to severe complications. In this case report, we present the hematological, biochemical, and histopathological findings that contributed to the diagnosis of secondary CM in a wild Clymene dolphin, <i>Stenella clymene</i>, stranded alive on a beach in northeastern Brazil.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e000625"},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful deslorelin implant treatment in a neutered female Pomeranian dog with Alopecia X.","authors":"Priscila Alves Bastos Coimbra, Aline Bomfim Vieira","doi":"10.29374/2527-2179.bjvm001325","DOIUrl":"https://doi.org/10.29374/2527-2179.bjvm001325","url":null,"abstract":"<p><p>The Pomeranian dog is recognized as one of the predisposed breeds for alopecia X, a noninflammatory hair cycle arrest disorder. Although it is considered a cosmetic issue unrelated to systemic illness, having a pet with alopecia can be distressing for owners. Sex steroid imbalance seems to influence the development of alopecia X, but the exact pathogenesis is still unknown. Although some treatment alternatives are currently available for alopecia X, results can vary, as well as costs, risks, and owner adherence. GnRH analogs have been used extensively in the modulation of sex hormone synthesis in humans. Previous studies support the use of the GnRH analog in treating male dogs with alopecia X, but current literature discourages its use in females. We aim to report the first scientific description of a neutered female dog with alopecia X successfully treated with a 4.7 mg deslorelin acetate implant after failing to respond to melatonin. Profuse hair regrowth took 9 months to occur after the first implant, but the treatment was considered uncomplicated, cost-effective, and safe.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e001325"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12017581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular detection and hematological alterations in dogs infected by <i>Babesia vogeli</i> from Paraguay.","authors":"Liz Aurora Castro Rojas, Elvio Gayozo, Guadalupe Gómez, Pedro Torres, Deydra Valenzuela Zaracho, Raquel Pedrozo Prieto","doi":"10.29374/2527-2179.bjvm008824","DOIUrl":"https://doi.org/10.29374/2527-2179.bjvm008824","url":null,"abstract":"<p><p>Babesiosis is a vector-borne disease caused by an intraerythrocytic protozoan parasite of the genus <i>Babesia</i>. There are several species of <i>Babesia</i> that can infect dogs, however, <i>B. vogeli</i> is the most widely distributed in South America. Anemia and thrombocytopenia are the most frequent hematologic alterations reported in dogs with babesiosis. The aim of the present study was to perform a molecular characterization of the <i>Babesia</i> species and describe the hematological findings regarding dogs with the <i>Babesia</i> infection. Blood samples were collected from 35 dogs living in an urban area with symptoms compatible with babesiosis, and the data was analyzed using molecular as well as hematological approaches. Molecular detection was performed by nested Polymerase Chain Reaction (PCR) targeting the 18S rRNA gene. To identify species, positives samples were sequenced and analyzed. Among the total number of samples, four (11%) were reported as positive due to a high identity (99-100%) and were clustered with the <i>B. vogeli</i> clade. The main hematological alteration found in infected dogs was thrombocytopenia (100%). Other abnormalities were also observed, although to a lesser extent, such as: normocytic normochromic anemia, monocytosis and eosinopenia. It is important to emphasize that this research is the first study involving molecular detection and hematology abnormalities in dogs with <i>B. vogeli</i> from Paraguay.</p>","PeriodicalId":72458,"journal":{"name":"Brazilian journal of veterinary medicine","volume":"47 ","pages":"e008824"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12017582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}