Mateo Marin-Cuartas, Bianca Dalbesio, Francesco Pollari, Matteo Scarpanti, Amedeo Anselmi, Manuela de la Cuesta, Miguel Sousa Uva, Jean-Philippe Verhoye, Francesco Musumeci, Fabio Barili, Alessandro Parolari
{"title":"Five-Year Mortality of Surgical and Transcatheter Aortic Valve Replacement in the Real-World Scenario: A Systematic Review and Meta-Analysis of Propensity Score Matching Studies.","authors":"Mateo Marin-Cuartas, Bianca Dalbesio, Francesco Pollari, Matteo Scarpanti, Amedeo Anselmi, Manuela de la Cuesta, Miguel Sousa Uva, Jean-Philippe Verhoye, Francesco Musumeci, Fabio Barili, Alessandro Parolari","doi":"10.21470/1678-9741-2024-0048","DOIUrl":"https://doi.org/10.21470/1678-9741-2024-0048","url":null,"abstract":"<p><strong>Introduction: </strong>Randomized controlled trials (RCTs) provide evidence of efficacy, while real-world data (RWD) demonstrate effectiveness in real-world practice. We designed a systematic review and meta-analysis of reconstructed time-to-event (RTE) data from propensity score matching studies comparing transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) to compare their effectiveness and evaluate the generalizability of TAVI indications.</p><p><strong>Methods: </strong>Systematic review of literature between 2007 and 2023 including propensity score matching studies comparing TAVI or SAVR that reported at least one-year Kaplan-Meier curves of endpoints.</p><p><strong>Results: </strong>Twenty-one studies were included (39538 participants). TAVI shows a higher all-cause mortality (hazard ratio [HR] 1.41; 95% confidence interval [CI] 1.34-1.47, P-value < 0.001), with a significant heterogeneity. The analysis of HR trend over time shows that TAVI superiority is limited to the first month with a steep reversal afterwards, when SAVR becomes clearly superior. All-cause mortality is significantly higher in TAVI in low-risk (HR 1.35; 95% CI 1.08-1.69, P-value < 0.001) as well as in intermediate (HR 1.73; 95% CI 1.35-2.22, P-value < 0.001) and high-risk (HR 1.61; 95% CI 1.38-1.88, P-value < 0.001) patients. The HR trend in the subgroups of risk confirms the data from the whole mixed population.</p><p><strong>Conclusion: </strong>In a real-word setting, TAVI is associated with higher incidence of all-cause death and maintains a survival benefit only in the first month after implantation. These results show that TAVI effectiveness may not reflect the efficacy demonstrated by RCTs and pose a threat to their external validity.</p>","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 4","pages":"e20240048"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12017277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rodrigo Cardoso Cavalcante, Laura Mercer-Rosa, Stephanie M Fuller
{"title":"What Is in a Name?","authors":"Rodrigo Cardoso Cavalcante, Laura Mercer-Rosa, Stephanie M Fuller","doi":"10.21470/1678-9741-2024-0221","DOIUrl":"https://doi.org/10.21470/1678-9741-2024-0221","url":null,"abstract":"","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 4","pages":"e20240221"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12017377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reviving Duran's Approach to Pericardial Valve Reconstruction in the Pulmonary Position Within the Right Ventricle-to-Pulmonary Artery Conduit: A Compelling Case Report.","authors":"Anupam Das, Alok Kumar Sharma, Anirudh Mathur","doi":"10.21470/1678-9741-2024-0123","DOIUrl":"https://doi.org/10.21470/1678-9741-2024-0123","url":null,"abstract":"<p><p>Various techniques of conduit repair have been employed during valve reconstruction. While Ozaki conduits have streamlined the procedure, their limited availability poses concerns. This case report presents 14-year-old patient with pulmonary atresia and an anomalous left anterior descending artery arising from the right sinus. A right ventricle-to-pulmonary artery conduit was created using Dacron® graft and a trileaflet valve employing Duran's technique of pericardial valve reconstruction, elucidating surgical methodology. In developing countries, the implementation of Duran's technique presents noteworthy advantage allowing for utilization of autologous tissue, addressing challenges associated with PTFE conduits. Unlike PTFE conduits, the results of Duran's technique at the pulmonary position needs to be followed up in a large number of cases.</p>","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 4","pages":"e20240123"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12017276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Catheter for Hemodialysis in Persistent Left Superior Vena Cava in a Patient with Aortic Valve Endocarditis.","authors":"Dejan Marković, Sonja Grković, Vladimir Tutuš, Emilija Nestorović, Duško Terzić, Radmila Karan, Milica Karadžić Kočica, Svetozar Putnik","doi":"10.21470/1678-9741-2023-0266","DOIUrl":"10.21470/1678-9741-2023-0266","url":null,"abstract":"<p><p>Persistent left superior vena cava (PLSVC) is a common congenital venous anomaly, usually associated with other congenital heart diseases (12%). Its incidence in the general population is 0.5%. In cardiac surgery patients, it is suspected when using the left subclavian vein or left internal jugular vein for central venous catheter or hemodialysis catheter placement. Transthoracic ultrasound exam is useful in confirming the position of catheters in the venous system by injecting a 5% glucose solution that can be visualized in the right atrium after administration through the catheter. Hemodialysis catheters can be inserted in the PLSVC with good catheter function and no major risk in increase of complications.</p>","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 3","pages":"e20230266"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gaurav Pandey, Salman Pervaiz Butt, Arshad Ghori, Naveen G Singh
{"title":"Evaluation of Transcutaneous Non-Invasive Blood Gas Analysis for Monitoring Gas Exchange in Pediatric Cardiac Surgical Patients Post Extubation.","authors":"Gaurav Pandey, Salman Pervaiz Butt, Arshad Ghori, Naveen G Singh","doi":"10.21470/1678-9741-2024-0010","DOIUrl":"10.21470/1678-9741-2024-0010","url":null,"abstract":"<p><strong>Introduction: </strong>Pediatric cardiac surgery patients need close post-extubation monitoring for ventilation. Non-invasive transcutaneous partial pressure of oxygen (TcPO2) and transcutaneous partial pressure of carbon dioxide (TcPCO2) offer continuous insights and in improving care.</p><p><strong>Objective: </strong>To investigate the correlation of transcutaneous blood gases (TcPO2, TcPCO2) with arterial blood gases i.e. arterial partial pressure of oxygen (PaO2) and arterial partial pressure of carbon dioxide (PaCO2).</p><p><strong>Methods: </strong>We conducted a study on 30 pediatric post-cardiac surgery patients (four months to three years old) who were extubated and exhibited stable hemodynamics (inotropic score ≤ 5), normal sinus rhythm, and no respiratory or heart failure signs. Continuous transcutaneous and intermittent arterial blood gas monitoring started one hour after extubation, with recordings every 30 minutes for four hours. A single observer conducted probe calibration and data recording to minimize variability, while analysis of 240 paired samples included correlation coefficient, linear regression, Bland-Altman analysis, and Mountain plot.</p><p><strong>Results: </strong>The r-value between PaCO2 and TcPCO2 was 0.95, r2-value of 0.9060 (P<0.001). Bland-Altman showed a bias of 2.579, and 95% limits of agreement were -6.4 to 1.3. The r-value between PaO2 and TcPO2 was 0.8942, r2-value of 0.7996 (P<0.001); bias of 20.171 and 95% limit of agreement of -0.5 to 40.9. The Mountain plot revealed a median of 2.57 for PaCO2 vs. TcPCO2 and 20.17 for PaO2 vs. TcPO2.</p><p><strong>Conclusion: </strong>Transcutaneous carbon dioxide values are interchangeable with arterial PaCO2 in our population study, acting as a surrogate in postoperative pediatric cardiac surgery. Confirmation with arterial blood gases is needed if discrepancies occur.</p>","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 3","pages":"e20240010"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel Vilela de Abreu Haickel Nina, Tainá Belisa Ferreira Rosa, Barbara Neiva Tanaka
{"title":"Perspectives of Pediatric Cardiology on the Creation of Pediatric Congenital Heart Surgery Subspecialty in Brazil.","authors":"Rachel Vilela de Abreu Haickel Nina, Tainá Belisa Ferreira Rosa, Barbara Neiva Tanaka","doi":"10.21470/1678-9741-2024-0200","DOIUrl":"10.21470/1678-9741-2024-0200","url":null,"abstract":"","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 3","pages":"e20240200"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Sales Fagundes, Diego Chemello, Luana Quintana Marchesan, Vitória Carolina Kohlrausch, Rafael Fortes Locateli, Eduardo Porto Santos, Isabella Klafke Brixner, Valéria Maria Limberger Bayer, Mateus Diniz Marques
{"title":"Predictors of Postoperative Hospital-Acquired Infection and Mortality Following Cardiac Surgery in a Low-Income Country: A Retrospective Cohort Study.","authors":"Camila Sales Fagundes, Diego Chemello, Luana Quintana Marchesan, Vitória Carolina Kohlrausch, Rafael Fortes Locateli, Eduardo Porto Santos, Isabella Klafke Brixner, Valéria Maria Limberger Bayer, Mateus Diniz Marques","doi":"10.21470/1678-9741-2024-0111","DOIUrl":"10.21470/1678-9741-2024-0111","url":null,"abstract":"<p><strong>Introduction: </strong>Recognizing the risk factors for postoperative hospital-acquired infection and mortality is crucial for better outcomes. We aimed to determine the risk predictors for postoperative hospital-acquired infection and death following cardiac surgery.</p><p><strong>Methods: </strong>This is a retrospective cohort study that included 880 consecutive adult patients who underwent cardiac surgery between 2015 and 2021. Multivariable logistic regression was performed to assess the predictors of postoperative hospital-acquired infection and mortality.</p><p><strong>Results: </strong>Patients who developed postoperative hospital-acquired infection had higher values on European System for Cardiac Operative Risk Evaluation score (4.01% vs. 2.51%; P=0.001), as well as longer hospital preoperative stay (9.44 vs. 8.28 days; P=0.049) and hospital length of stay (28.41 vs. 16.16 days; P<0.001). After multivariable analysis, predictors of postoperative hospital-acquired infection were longer hospital preoperative stay (odds ratio 1.024; 95% confidence interval 1.005-1.044; P=0.009), higher body mass index (odds ratio 1.043; 95% confidence interval 1.008-1.079; P=0.015), and longer extracorporeal circulation time (odds ratio 1.007; 95% confidence interval 1.003-1.012; P<0.001). Both longer extracorporeal circulations time and postoperative hospital-acquired infection were significantly associated with higher mortality before hospital discharge (odds ratio 1.012; 95% confidence interval 1.006-1.019; P<0.001; and odds ratio 2.418; 95% confidence interval 1.385-4.233; P=0.001, respectively).</p><p><strong>Conclusion: </strong>Extended preoperative hospitalization, body mass index, and extracorporeal circulation time are correlated with heightened postoperative hospital-acquired infection rates. Moreover, longer extracorporeal circulation time and postoperative hospital-acquired infection incidence emerged as significant predictors of mortality following cardiac surgery.</p>","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 2","pages":"e20240111"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksey V Voitov, Meline G Morsina, Serezha N Manukian, Ilya A Soynov, Nataliya R Nichay, Yury Yu Kulyabin, Aleksey N Arkhipov, Manolis G Pursanov, Artem V Gorbatykh, Alexander V Bogachev-Prokophiev
{"title":"Comparative Study on the Outcomes of Right Ventricular Outflow Tract Stenting vs. Modified Blalock-Taussig Shunt in Patients with Tetralogy of Fallot: A Prospective Randomized Trial.","authors":"Aleksey V Voitov, Meline G Morsina, Serezha N Manukian, Ilya A Soynov, Nataliya R Nichay, Yury Yu Kulyabin, Aleksey N Arkhipov, Manolis G Pursanov, Artem V Gorbatykh, Alexander V Bogachev-Prokophiev","doi":"10.21470/1678-9741-2023-0478","DOIUrl":"10.21470/1678-9741-2023-0478","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate pulmonary vascular development and outcomes of complete correction following palliative treatment in infants with critical tetralogy of Fallot.</p><p><strong>Methods: </strong>This prospective, randomized, two-center study included infants with tetralogy of Fallot who underwent surgery between June 2018 and 2022. The patients were divided into two groups - those who underwent stenting of the right ventricular outflow tract (stent group, n=21) and those who underwent modified Blalock-Taussig shunt placement (shunt group, n=21).</p><p><strong>Results: </strong>In the stent group, a significantly greater increase in Nakata index was observed, with mean values rising from 104.2 to 208.6 mm2/m2, compared to an increase from 107.3 to 169.4 mm2/m2 in the shunt group (P<0.01). According to the mixed model analysis, the rate of growth of the right pulmonary artery in the stent group was 2.05*10-2 z score/day, which was 3.01 times greater than that in the shunt group (P<0.01). The rate of growth of the left pulmonary artery in the stent group was 2.3*10-2 z score/day, which was 1.47 times greater than that in the shunt group (P<0.01). In one patient (4.8%), after 76 days following the stenting of the RVOT, a severe infectious process with sepsis occurred, leading to a fatal outcome. Complete correction in the stent group involved transannular patch repair of the right ventricular outflow tract to the pulmonary artery in 12 patients (60%), while the same procedure was performed in 15 patients (71.4%) in the shunt group (P=0.52).</p><p><strong>Conclusion: </strong>Stenting of the right ventricular outflow tract provides hemodynamic stabilization and symmetric growth of the pulmonary vascular bed compared to the formation of a modified Blalock-Taussig shunt.</p>","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 2","pages":"e20230478"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitrios Starvridis, Arian Arjomandi Rad, Paola Keese Montanhesi, Hristo Kirov, Max Wacker, Panagiotis Tasoudis, Murat Mukharyamov, Ricardo E Treml, Jens Wippermann, Torsten Doenst, Ibrahim Sultan, Michel Pompeu Sá, Tulio Caldonazo
{"title":"Mini-Sternotomy vs. Right Anterior Mini-Thoracotomy for Surgical Aortic Valve Replacement - A Systematic Review and Meta-Analysis.","authors":"Dimitrios Starvridis, Arian Arjomandi Rad, Paola Keese Montanhesi, Hristo Kirov, Max Wacker, Panagiotis Tasoudis, Murat Mukharyamov, Ricardo E Treml, Jens Wippermann, Torsten Doenst, Ibrahim Sultan, Michel Pompeu Sá, Tulio Caldonazo","doi":"10.21470/1678-9741-2024-0211","DOIUrl":"10.21470/1678-9741-2024-0211","url":null,"abstract":"<p><strong>Introduction: </strong>Minimally invasive techniques for aortic valve replacement have become increasingly popular. The most common minimally invasive approaches are mini-sternotomy and right anterior mini-thoracotomy. We aimed to review the literature and compare clinical outcomes for these two approaches.</p><p><strong>Methods: </strong>Three databases were assessed. The primary endpoint was perioperative mortality. The secondary endpoints were reoperation for bleeding, stroke, operation duration, intensive care unit length of stay, cardiopulmonary bypass time, cross-clamping time, hospital length of stay, paravalvular leak, renal complications, conversion to full sternotomy, permanent pacemaker implantation, and wound infection. Random effects models were performed.</p><p><strong>Results: </strong>Ten studies were included in the meta-analysis (30,524 patients). There was no difference in perioperative mortality between groups (odds ratio: 0.83; 95% confidence interval 0.57-1.21; P=0.33). In comparison with mini-sternotomy, right anterior mini-thoracotomy showed higher rates of reoperation for bleeding (odds ratio: 0.69; 95% confidence interval 0.50-0.97; P=0.03), lower rates of stroke (odds ratio: 1.27; 95% confidence interval 1.01-1.60; P=0.04), and longer operation duration (standard mean difference: -0.58; 95% confidence interval -1.01 to -0.14; P=0.01). Other secondary endpoints were not statistically significant.</p><p><strong>Conclusion: </strong>The results suggest that both techniques present similar perioperative mortality rates for aortic valve replacement. However, right anterior mini-thoracotomy is associated with higher rates of reoperation for bleeding, lower rates of stroke, and longer operation duration time.</p>","PeriodicalId":72457,"journal":{"name":"Brazilian journal of cardiovascular surgery","volume":"40 3","pages":"e20240211"},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}