Brain & NeuroRehabilitation最新文献_第3页

Biofluid-based Biomarkers in Traumatic Brain Injury: A Narrative Review. 创伤性脑损伤中基于生物流体的生物标志物：叙述性综述。

Brain & NeuroRehabilitation Pub Date : 2024-03-18 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e8

Da-Sol Kim, Gi-Wook Kim

{"title":"Biofluid-based Biomarkers in Traumatic Brain Injury: A Narrative Review.","authors":"Da-Sol Kim, Gi-Wook Kim","doi":"10.12786/bn.2024.17.e8","DOIUrl":"https://doi.org/10.12786/bn.2024.17.e8","url":null,"abstract":"Traumatic brain injury (TBI) is a complex condition characterized by a multifaceted pathophysiology. It presents significant diagnostic and prognostic challenges in clinical settings. This narrative review explores the evolving role of biofluid biomarkers as essential tools in the diagnosis, prognosis, and treatment of TBI. In recent times, preclinical and clinical trials utilizing these biofluid biomarkers have been actively pursued internationally. Among the biomarkers for nerve tissue proteins are neuronal biomarkers like neuronal specific enolase and ubiquitin C-terminal hydrolase L1; astroglia injury biomarkers such as S100B and glial fibrillary acidic protein; axonal injury and demyelination biomarkers, including neurofilaments and myelin basic protein; new axonal injury and neurodegeneration biomarkers like total tau and phosphorylated tau; and others such as spectrin breakdown products and microtubule-associated protein 2. The interpretation of these biomarkers can be influenced by various factors, including secretion from organs other than the injury site and systemic conditions. This review highlights the potential of these biomarkers to transform TBI management and emphasizes the need for continued research to validate their efficacy, refine testing platforms, and ultimately improve patient care and outcomes.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"17 1","pages":"e8"},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Undernutrition Risk on Rehabilitation Outcomes in Ischemic Stroke Survivors: A Hospital-Based Study. 营养不良风险对缺血性脑卒中幸存者康复结果的影响：一项基于医院的研究

Brain & NeuroRehabilitation Pub Date : 2024-02-26 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e7

Daniela Figueiredo Corrêa Pereira, Karen Barros Parron Fernandes, Andreo Fernando Aguiar, Juliano Casonatto

{"title":"The Impact of Undernutrition Risk on Rehabilitation Outcomes in Ischemic Stroke Survivors: A Hospital-Based Study.","authors":"Daniela Figueiredo Corrêa Pereira, Karen Barros Parron Fernandes, Andreo Fernando Aguiar, Juliano Casonatto","doi":"10.12786/bn.2024.17.e7","DOIUrl":"https://doi.org/10.12786/bn.2024.17.e7","url":null,"abstract":"Patients experiencing a cerebrovascular event are vulnerable to declining nutritional status, hindering rehabilitation. This study aims to analyze the association between malnutrition risk and hospital rehabilitation indicators in ischemic stroke survivors (ISS). This analytical study examined medical records of 160 adult patients (69.3 ± 13 years). Undernutrition risk (UR; independent variable) and rehabilitation indicators (dependent variables) like hospital stay, clinical outcome, functionality, stroke severity, food intake, mobility (bedridden), mechanical ventilation, and enteral nutrition were assessed. Data were dichotomized, and the chi-square test identified associations (p ≤ 0.05), followed by Poisson regression for prevalence ratios. Patients at UR had 2-fold higher risk of death (95% confidence interval [CI], 0.99-4.79), 1.8-fold higher risk of high stroke severity (95% CI, 1.06-3.11), 76% higher chance of being bedridden (95% CI, 1.28-2.44), and 3-fold higher risk of mechanical ventilation (95% CI, 1.20-9.52). UR in hospitalized ISS is associated with deteriorating rehabilitation indicators, including mobility, decreased food intake, mechanical ventilation use, and neurological deficit, indicating an increased mortality risk post-stroke.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"17 1","pages":"e7"},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Rhin sling," A Novel Type of Shoulder Sling in Post-Stroke Shoulder Subluxation: A Case Report. "Rhin 吊衣"，一种治疗中风后肩关节脱位的新型肩部吊衣：病例报告。

Brain & NeuroRehabilitation Pub Date : 2024-02-19 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e6

Soohoan Lee, Sun Im, Il Soo Kim, Jae Yi Kim

引用次数: 0

Update on Non-invasive Brain Stimulation on Stroke Motor Impairment: A Narrative Review. 无创脑电刺激治疗脑卒中运动障碍的最新进展：叙述性综述。

Brain & NeuroRehabilitation Pub Date : 2024-01-31 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e5

Sejoon Kim, Hae-Yeon Park

引用次数: 0

Attitude Toward Virtual Rehabilitation and Active Video Games Among Therapists in Korea: A Nationwide Survey. 韩国治疗师对虚拟康复和主动视频游戏的态度：全国调查。

Brain & NeuroRehabilitation Pub Date : 2024-01-19 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e4

Hee-Mun Cho, Hyunji Kim, Jihui Jang, Seungwoo Cha, Won Kee Chang, Bong-Keun Jung, Dae-Sung Park, Sungju Jee, Sung-Hwa Ko, Joon-Ho Shin, Ji Soo Choi, Won-Seok Kim, Nam-Jong Paik

{"title":"Attitude Toward Virtual Rehabilitation and Active Video Games Among Therapists in Korea: A Nationwide Survey.","authors":"Hee-Mun Cho, Hyunji Kim, Jihui Jang, Seungwoo Cha, Won Kee Chang, Bong-Keun Jung, Dae-Sung Park, Sungju Jee, Sung-Hwa Ko, Joon-Ho Shin, Ji Soo Choi, Won-Seok Kim, Nam-Jong Paik","doi":"10.12786/bn.2024.17.e4","DOIUrl":"https://doi.org/10.12786/bn.2024.17.e4","url":null,"abstract":"In this study, we conducted a survey targeting 191 physical therapists (PTs) and 159 occupational therapists (OTs) in South Korea to explore attitudes toward virtual rehabilitation. Utilizing the Korean version of the ADOPT VR by Glegg et al., OT exhibited significantly more experience with virtual reality (VR) and active video games (AVG) than PT. Therapists with VR/AVG experience scored significantly higher in most categories, and the scores in each category were significantly correlated with the Behavioral Intention category, reflecting the willingness to use VR/AVG. The biggest barriers identified were insufficient funds and setup assistance for the equipment. Differences in responses between the groups with and without VR/AVG experience were most prominent in terms of lack of interest and funding. Therapists' attitudes, perceptions, and intentions toward VR/AVG are crucial factors in the establishment and implementation of VR/AVG; thus, the results of this study provide valuable evidence for future policies related to VR/AVG in rehabilitation medicine.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"17 1","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intrathecal Baclofen Injection Efficacy for Spasticity Management in Patients With Stroke: A Meta-Analysis. 鞘内注射巴氯芬治疗脑卒中患者痉挛的疗效：一项 Meta 分析。

Brain & NeuroRehabilitation Pub Date : 2024-01-17 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e3

Ki Deok Park, Min-Keun Song

{"title":"Intrathecal Baclofen Injection Efficacy for Spasticity Management in Patients With Stroke: A Meta-Analysis.","authors":"Ki Deok Park, Min-Keun Song","doi":"10.12786/bn.2024.17.e3","DOIUrl":"https://doi.org/10.12786/bn.2024.17.e3","url":null,"abstract":"Although intrathecal baclofen injections have been used for spasticity management regarding stroke, spinal cord injury, and central nervous system diseases, their relative efficacy is controversial. This systematic review scoured 3 multinational electronic databases (Cochrane Library, MEDLINE, and Embase) to isolate relevant studies. We analyzed non-randomized studies and randomized control trials (RCTs) with direct comparisons against other spasticity management interventions for adult stroke patients. Risk of Bias (RoB) and the Risk of Bias Assessment tool for Non-randomized Studies evaluations were implemented with Cochrane's RoB tool. Meta-analysis was performed with Revman 5.4, and evidence validity was assessed with the Grading of Recommendations, Assessment, Development, and Evaluations method. Lastly, the intrathecal baclofen injection meta-analysis included 2 RCTs and 7 non-RCTs for assessing spasticity and 4 non-RCTs to measure gait velocity. Based on this data, intrathecal baclofen injection significantly impacted spasticity and gait speed. Thus, intrathecal baclofen injection can potentially treat severe spasticity unresponsive to conventional spasticity therapy. Furthermore, clinicians must consider individual patient characteristics and conditions when contemplating intrathecal baclofen injection for spasticity intervention.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"17 1","pages":"e3"},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quadriplegia, Dysphagia and Ataxia Manifested in a Child With COVID-19 Related Acute Necrotizing Encephalopathy: A Case Report. 一名患 COVID-19 相关急性坏死性脑病的儿童出现四肢瘫痪、吞咽困难和共济失调：病例报告。

Brain & NeuroRehabilitation Pub Date : 2024-01-04 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e2

Young-Su Ku, Kyung-Lim Joa, Myeong-Ok Kim, Chang-Hwan Kim, Han-Young Jung

{"title":"Quadriplegia, Dysphagia and Ataxia Manifested in a Child With COVID-19 Related Acute Necrotizing Encephalopathy: A Case Report.","authors":"Young-Su Ku, Kyung-Lim Joa, Myeong-Ok Kim, Chang-Hwan Kim, Han-Young Jung","doi":"10.12786/bn.2024.17.e2","DOIUrl":"https://doi.org/10.12786/bn.2024.17.e2","url":null,"abstract":"Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, presents primarily with respiratory symptoms. However, children with COVID-19 are usually asymptomatic or mild acute symptoms and also neurological manifestations have also been observed. We report the case of a 7-year-old girl who presented with high fever and altered mental status, leading to a diagnosis of COVID-19 and acute necrotizing encephalopathy (ANE). The patient received intensive medical care in the intensive care unit and subsequently underwent rehabilitation programs due to neurological functional sequelae. Neurological complications in COVID-19, including ANE, may result from potential viral nerve involvement, cytokine storms, and the blood-brain barrier disruption. Early rehabilitation plays a pivotal role in managing COVID-19-related neurological complications and enhancing patients' functional outcomes. Further research is essential to gain a better understanding of the mechanisms and treatment strategies for neurological manifestations in pediatric COVID-19 patients, particularly those with multisystem inflammatory syndrome in child.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"17 1","pages":"e2"},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain & NeuroRehabilitation Pub Date : 2023-12-22 eCollection Date: 2024-03-01 DOI: 10.12786/bn.2024.17.e1

Mijung Jang, Heedong Park, Miyoung Kim, Galam Kang, Hayan Shin, Donghyun Shin, KyooSang Kim

{"title":"Health-Related Quality of Life of Post-Stroke Patients in a Public Hospital.","authors":"Mijung Jang, Heedong Park, Miyoung Kim, Galam Kang, Hayan Shin, Donghyun Shin, KyooSang Kim","doi":"10.12786/bn.2024.17.e1","DOIUrl":"https://doi.org/10.12786/bn.2024.17.e1","url":null,"abstract":"This study aimed to identify the correlation between influencing factors of activities of daily living (ADLs), mental health, and health-related quality of life (HRQoL) among post-stroke patients who enrolled in a transitional care service in a public hospital. This cross-sectional study involved 67 stroke patients who were enrolled in a transitional care service and visited the outpatient clinic at a public hospital in Seoul between March and December 2022. Their general characteristics, ADLs, mental health, and HRQoL were assessed. The data were analyzed using independent samples t-tests, analysis of variance, and Pearson correlation analysis, and the influencing factors were analyzed using regression analysis. HRQoL showed a statistically significant difference between patients living in different types of arrangements (t = 2.50, p = 0.015), and patients scores on the modified Rankin Scale (t = 7.08, p < 0.001). HRQoL was also significantly correlated with ADLs and mental health in stroke patients (r = -0.59, p < 0.001; r = -0.41, p < 0.001, respectively). Meanwhile, stroke severity (β = -0.30, p = 0.002), living arrangements (β = -0.30, p = 0.009) and ADLs (β = -0.45, p < 0.001) were found to influence HRQoL (F = 6.87, p < 0.001, R2 = 0.47). Reduced dependence for ADLs, improvements in symptoms consequent to stroke, and support related to living arrangements contributed to improved HRQoL and interventions for post-stroke patients in the transitional care service of a public hospital.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"17 1","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cerebral Infarction and Recovery in a 12-Year-Old Child With Intracranial Fibromuscular Dysplasia. 颅内纤维肌肉发育不良12岁儿童脑梗死及康复。

Brain & NeuroRehabilitation Pub Date : 2023-11-09 eCollection Date: 2023-11-01 DOI: 10.12786/bn.2023.16.e35

Min Hwan Kim, Jae In Lee, Shin-Seung Yang

引用次数: 0

Compensatory Hyperactivity of the Ipsilesional Red Nucleus in a Patient With Somatosensory Cortex Damage: A Case Report. 体感觉皮质损伤患者同侧红核代偿性亢进1例报告。

Brain & NeuroRehabilitation Pub Date : 2023-11-06 eCollection Date: 2023-11-01 DOI: 10.12786/bn.2023.16.e33

Jeongeun Lee, Eunjee Lee, Shahid Bashir, Gyu Jin Kim, Suk Hoon Ohn, Kwang-Ik Jung, Woo-Kyoung Yoo

引用次数: 0