Biomedical science and clinical research最新文献

{"title":"Transdermal and Moisturizing Effects of Novel Supramolecular Hyaluronic Acid","authors":"Haimiao Wang, Zhongxia Jin, Xiaoqing Lu, L. Wang, Xiyin Sheng, Shaocheng Wang, Tongxun Xu, Peng He, Chen Li","doi":"10.33140/bscr.02.02.06","DOIUrl":"https://doi.org/10.33140/bscr.02.02.06","url":null,"abstract":"Hyaluronic acid (HA) is an important macromolecular polymer widely existing in skin, which can lock water molecules in the skin.Due to the barrier effect of skin stratum corneum, high molecular weight HA cannot enter the deep skin, while low molecular weight HA has ability limited to maintian water.Nowadays, HA injection is widely used as a supplement method, which brings many disadvantages due to its invasiveness.Therefore, in this study, the ionic liquid induction technology was used to transform the macromolecular HA into the supermolecular state. Through in vitro transdermal experiment and human skin moisturizing experiment, it was proved that the supermolecular state HA has better transdermal and skin moisturizing ability, which provide a new potential method for non-invasive exogenous supplementation of HA.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81099718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of “Damage Control Orthopedics” Strategy in the Treatment of Severe Gunshot Wounds of the Limbs","authors":"A. Domanskyi","doi":"10.33140/bscr.02.02.05","DOIUrl":"https://doi.org/10.33140/bscr.02.02.05","url":null,"abstract":"Objectives: The objectives of this study were to evaluate the incidence and nature of gunshot wounds of the limbs in the general structure of combat trauma, and study the features of DCO (Damage Control Orthopedics) patient management strategy in the conditions of a regional hospital as a stage of care for this pathology. Background: Limb injuries account for between 52.3% and 60.1% of combat casualties. The problem of surgical management of limb gunshot wounds is of particular relevance at the present stage of active use of firearms. Thus, adequate choice of surgical treatment strategy for limb gunshot wounds is an important condition for preserving life and preventing severe complications in combat casualties. Methods: The study was conducted among 1000 injured from the combat zone during the period from 24.02.22 to 15.04.22. The trauma and orthopedic surgery department of “Dnipropetrovsk Regional Clinical Hospital named after I.I. Mechnikov” mainly performed secondary surgical debridement of wounds, comprehensive surgical and medical prevention of complications in the injured. Injury severity was assessed using the ISS (Injury Severity Score) based on the AIS (Abbreviated Injury Scale), which assesses the severity of injuries to several areas of the body. Results: DCO strategy was used in 287 (55.1%) injured patients in severe and extremely severe condition (16 points or higher on the ISS scale). A total of 602 surgical operations were performed in 287 injured patients. On average, 2.1±0.6 interventions per one injured person were performed. Overall mortality among victims with gunshot wounds of the limbs was 3.6% (19 wounded out of 521). In all cases there were polytrauma (100%), in 4 (21.1%) cases they were through-and-through injuries, in 2 (10.5%) - with the compartment syndrome development. Conclusions: Differentiated DCO strategy in the surgical treatment of the critically and severely injured (16 points and above on the ISS scale) are essential to save the lives of soldiers in the first period of traumatic illness and to prevent complications of the second and third periods of traumatic illness","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"79 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77511545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Worlds of Attitudes Towards Anti-COVID-19 Vaccination: a Multi-Sited Approach to Contextualise a European Society","authors":"D. Sandu","doi":"10.33140/bscr.02.02.04","DOIUrl":"https://doi.org/10.33140/bscr.02.02.04","url":null,"abstract":"What does the balance of attitudes towards the anti-COVID-19 vaccination look like in an Eastern European Society of today? We compared what the Romanians in Romania, interviewed on the subject in the Flash Eurobarometer 494, say with what those from other European Union countries say. From the “discussion with the data” we understood that there are not only ani-vaxxers, pro-vaxxers and hesitants. Other categories matter, between them. We tried to see how much it mattered, in the pro- or anti-vaccination beliefs, not only the usual demographic conditionings of education, age, gender or residential environment, but also personal pre-pandemic vaccination experiences, as an adult, or trust in institutions relevant to the COVID-19 vaccination.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83413874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dictatorial Psychopathological Commination in Server-Side Public Mental & Psychological Menace","authors":"Yang I. Pachankis","doi":"10.33140/bscr.02.02.03","DOIUrl":"https://doi.org/10.33140/bscr.02.02.03","url":null,"abstract":"Background: Communist formation introduced Marxist’s non-falsifiable anthropocentric theory for ideology and discourse. The form of communication sustaining torture has been noticed in the Chinese indoctrination both in education and mass communication. The research adopted scientific methods in observation to the Marxist structuralism with psychoanalysis of dominance in power-incentivized structuralism. Aim: With the global authoritarian drawbacks and emergence of dictatorship in the structural realist powers, the psychopathology of modern & contemporary cyber-based informatics penetrations with nuclear threat semantics is impacting global mental & psychological health, and especially for the LGBTQIA+ individuals. The research aims to mitigate the harms that transgress the Geneva Conventions and against the spirit of Universal Declaration of Human Rights. Methods: The research adopted a media analysis approach to the sexological elements in anthropological and sociological developments. It focuses on the derivatives of Oedipus Complex with relation to death wish that impact the LGBTQIA+ suicidal ideations in the structured cybercrimes, with a Gestalt psychoanalysis in informatics. The research conceived a somatic method in media psychology counteracting the media-based extension of gender & sexuality castes. Results: The Bell curve of memory were retrieved on the fundamental hypothesis of LGBTQIA+ stigmatization with new combinations in power structure, cosmological, and anthropological consciousness re-combinations. The multilateral dictatorial semantic spread in the cyber-information domains through the monopolization of the Internet Corporation for Assigned Names and Numbers (ICANN) was conceptualized as a structural source of dictatorial psychopathology epidemiology with artificial intelligence (AI). Military cyber psychological warfare spillover in the civil economy is recognized to be the source of global mental & psychological disparities, possibly the contributing factor for LGBTQIA+ suicidal ideation, and derogation of human security","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79968833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Post-Genocide Paradoxes of Peace With the Aging of Criminals — Phenomenological Studies on the Genocides of PRC","authors":"Yang I. Pachankis","doi":"10.33140/bscr.02.02.02","DOIUrl":"https://doi.org/10.33140/bscr.02.02.02","url":null,"abstract":"Introduction: The article dismantles genocide distortions as means of mass torture and purposes beyond genocide denials. The research analyzes into the organizational psychopathology behind the consistent genocides in PRC. Objective: The research dissects into the organizational culture of PRC genocide, and separates it from the biochemical & physiological harms of neuro-cognitive warfare. It is an indiscriminate attack. Method: With a brief explanation on my treatment of a tortured victim, I solicit the information my patient tried to convey to me from psychoanalysis. Further on, I provide inferential evidence on the biochemical sources of harm and the differentiated purposes of genocide denials behind neuro-cognitive warfare. The threat is analyzed to be de facto kinetic. Results: Evidences suggest the organizational psychopathological expansions have proliferated the genocide crimes to a scale of crime against humanity. Trial in absentia and unconditional surrender of the current CPC-led PRC regime is only appropriate to restore peace to the region, with UN Peacekeeping Missions for rebuilding a functional democracy.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85814991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Questioning the Administrative Accountability of the ITU on the QUESS Oversight","authors":"","doi":"10.33140/bscr.02.02.01","DOIUrl":"https://doi.org/10.33140/bscr.02.02.01","url":null,"abstract":"In accordance with the SI unit of the unperturbed ground-state hyperfine transition frequency of the cesium 133 atom, Eutelsat has secured the safety procedures of telecommunication decays in the development of quantum communication technology. As observers of the International Atomic Energy Agency (IAEA), the International Telecommunication Union (ITU) is bound for intergovernmental observers with specialized agencies of the United Nations and IAEA based on reciprocity. The apparent overpowered photon beam of the Quantum Experiment at Space Scale (QUESS) military intelligence purposed telecommunication encryption designs launched around 2016, along with a German photon experiment directed at earth, were neither intervened by the ITU nor the IAEA. According to Article 10 63. 1. of the International Telecommunication Convention, the ITU is responsible with International Frequency Registration Board for the administrative accountability, however, Article 8 54. (3) gives rent to the administrative powers of the organization for agenda settings by the Secretary-General. The article analyzes and questions the administrative accountability of the ITU in the oversight of the high energy photon applications in the telecommunications and if the IAEA was informed by the International Frequency Registration Board on this matter. Correlated behaviors in the cyber-based criminology, with significant impact on public health and biological integrity from such operations, is supplemented for the alteration of financial & economic incentives in the democratic systems, which constituted the liberal International institutionalism. The research contends that criminal liabilities ought to be sought for in the criminological chain.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135722099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of COVID mRNA Vaccine Linked Antiphospholipid Syndrome","authors":"","doi":"10.33140/bscr.02.01.13","DOIUrl":"https://doi.org/10.33140/bscr.02.01.13","url":null,"abstract":"Introduction: There have been several reports of thrombotic adverse events after administration of the mRNA Covid vaccine [1, 2]. The onset of autoimmune disease has also been reported following viral illness as well as following vaccination [3]. Antiphospholipid syndrome (APS) is an autoimmune hypercoagulable state that can result in thrombotic events such as deep venous thrombosis, pulmonary embolus, and stroke [4]. Antiphospholipid antibodies (aPLs) are associated with APS syndrome. However, not all individuals with aPLs will develop antiphospholipid syndrome as antiphospholipid antibodies are also present in up to 5% of the healthy population. Antiphospholipid antibodies have been reported after infections and vaccines. Antiphospholipid syndrome has also been reported following natural Covid infection [5]. Herein we present a case of antiphospholipid syndrome following Covid mRNA vaccination associated with life-threatening thrombosis, dyspnea, and hypoxia coupled with multiple adverse reactions affecting skin, respiratory, nervous, and vascular systems.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135723172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Segmented Linear Regression Under a Bayesian Approach to Detect Climate Change in Different Regions of the World","authors":"","doi":"10.33140/bscr.02.01.12","DOIUrl":"https://doi.org/10.33140/bscr.02.01.12","url":null,"abstract":"In this work we study the behavior of some climate data (annual temperature and precipitation averages) obtained from climate stations in eleven countries in different regions of the world. One of the goals of the study is to determine whether the climate variables have change-points that could indicate the possible beginning of a change in climate. Another goal is to analyze the possible changes detected by the change-points in terms of the linear trends of the climate variables under investigation. Based on the information provided, differences between different regions in terms of the locations of the change-points and the changes they produce may also be inferred. The data sets used in the study consist of the annual averages of the twelve monthly temperature averages and the annual averages of the total rain precipitation observed in each one of the twelve months of the year obtained over a period of time from the end of the 19th century to the end of the 20th century. Segmented linear regression models are used to study the existence of possible changes in the behavior of climatic variables, as well as the types of changes produced.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"900 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77484490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction of Porencephalic Cyst Along with the Revival of Motor Control Using the Deep Brain Sound Stimulation (DBSS) Technology as a Novel Approach","authors":"","doi":"10.33140/bscr.02.01.11","DOIUrl":"https://doi.org/10.33140/bscr.02.01.11","url":null,"abstract":"A porencephalic cyst is a rare disorder, with the etiology of brain parenchymal loss as a result of perinatal cerebral ischemia or hemorrhage leading to the accumulation of cerebrospinal fluid within the parenchyma. It is diagnosed radiologically, and management depends on the clinical manifestations. The present case depicts a porencephalic cyst presenting with cerebral right-sided hemiparesis in adulthood. The cyst dimensions measured 2.6*0.6*0.5 cm in the left lateral ventricle with associated hemiparesis of the right side at the time of the first MRI scan before Deep Brain Sound Stimulation (DBSS) sessions. A reduction in the size of the cyst to 16*7*7 mm and then to a subsequent 8 mm was documented during a novel, non-invasive deep brain stimulation via sound (DBSS) treatment. In addition, right upper and lower limb power increased to 5/5 with improved coordination in a complete neurological evaluation. DEXA scan showed an increased bone density and muscle bulk.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91192105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studying Vaccination Coverage and Design of Short Message Service Based Reminder to Improve Children Vaccination Coverage in Hawassa; Sidama Region; Ethiopia","authors":"","doi":"10.33140/bscr.02.01.07","DOIUrl":"https://doi.org/10.33140/bscr.02.01.07","url":null,"abstract":"A vaccine is a kind of remedy that trains the body’s protection system so that it can combat an infection. The national routine immunization coverage in Ethiopia is low. Among the main reason for defaulting children vaccinations are disremembering the appointment date, communication gap between service providers and the community, knowhow about vaccination and etc. This work is to investigate vaccination coverage in Hawassa city and main reasons of vaccination drop out, and then provide a solution for that main reason. Data was collected from 360 children whose age is between 1 to 2 years who live in Hawassa city. The data analysis result showed that only 51% of the children are fully vaccinated; and the main reason for vaccination dropout which weighs 57% was found to be disremembering the appointment date. Providing a solution to not only one of the main reasons but also for the one which weighs the most in the city of this study will improve the vaccination coverage. As the main reason is found to be disremembering the vaccination appointment date, this work provides a Short Message Service (SMS) based automatic reminding system. The design part uses database, OzekiNG network gateway and global system for mobile communication modem with active subscriber identity module. In this system the health extension workers will register the clients’ detailed information including appointment dates during the birth of baby that will be accessed periodically by the OzekiNG to send the reminder SMS to the mothers one day a head to the day of vaccination. After automatic reminding mechanism was developed and implemented, coverage of fully vaccinated children increases from 51% to 71% and the problem of forgetting appointment date decreases from 57% to 14%. The efficiency of the developed system is found to be 85%. From the above-mentioned results and the current available communication mechanisms, it can be concluded that the reminding system can be simply implemented to improve the child vaccination coverage by bridging the gap due to disremembering the vaccination appointment date.","PeriodicalId":72393,"journal":{"name":"Biomedical science and clinical research","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135185860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}