Biomedical engineering advances最新文献

{"title":"Problems and Countermeasures in Cost Control of Civil Construction Engineering","authors":"He Zhou","doi":"10.26855/ea.2023.08.001","DOIUrl":"https://doi.org/10.26855/ea.2023.08.001","url":null,"abstract":"","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135203795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In situ synchrotron quantitative analysis of competitive adsorption tendency of human serum protein to different clinical hemodialysis membranes and assessment of potential impacts","authors":"Amira Abdelrasoul ,&nbsp;Heloisa Westphalen ,&nbsp;Denis Kalugin ,&nbsp;Huu Doan ,&nbsp;Ahmed Shoker","doi":"10.1016/j.bea.2023.100104","DOIUrl":"10.1016/j.bea.2023.100104","url":null,"abstract":"<div><p>Protein adsorption on hemodialysis (HD) membrane matrices and surfaces is a highly undesirable process, as it triggers complement activation and leads to severe health complications for HD patients. However, there is a lack of systematic research investigating the correlation between membrane characteristics and their performance in the dialysis process. This study aims to provide a comprehensive understanding of the competitive adsorption tendencies of three human serum proteins (albumin (HSA), fibrinogen (FB), and transferrin (TRF)) on clinical dialysis membranes composed of polyethersulfone (PES), polyacrylonitrile (PAN), and polyvinyl fluoride (PVDF) polymers. To assess membrane morphology across the membrane cross-section, <em>in situ</em> synchrotron radiation micro-computed tomography (SR-µCT) imaging was conducted at the Canadian Light Source (CLS). Protein adsorption was analyzed qualitatively and quantitatively using an innovative synchrotron-based X-ray tomography technique. To determine the mutual influence of protein species on overall protein adsorption, adsorption from single-protein solutions was compared to adsorption from a protein mixture. Regarding single-protein adsorption, the PVDF membrane exhibited 40% less adsorption of HSA compared to the PES membrane. Conversely, FB adsorption was approximately 25% higher on the PVDF membrane compared to the PES membrane. The PAN membrane showed similar levels of HSA adsorption as the PES membrane and similar levels of FB adsorption as the PVDF membrane. In the case of adsorption from the protein mixture, a suppression of HSA adsorption and replacement of HSA with FB were observed. Consequently, the initial solution with a HSA content of 92% resulted in an adsorbed layer containing approximately 75–80% HSA across all the studied membranes. TRF adsorption remained unaffected by the presence of other proteins, consistent across all three membranes. Notably, the PES membrane exhibited the most significant change in the adsorbed protein composition between single-protein and multi-protein adsorption. In addition, this study comprehensively assesses the impact of fibrinogen adsorption on dialysis, including its consequences, blood activation, and implications for quality of life.</p></div>","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"6 ","pages":"Article 100104"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42910843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polylactic acid/silicon nitride biodegradable and biomedical Nanocomposites with optimized rheological and thermomechanical response for material extrusion additive manufacturing","authors":"Nectarios Vidakis ,&nbsp;Markos Petousis ,&nbsp;Nikolaos Michailidis ,&nbsp;Vassilis Papadakis ,&nbsp;Nikolaos Mountakis ,&nbsp;Apostolos Argyros ,&nbsp;Evgenia Dimitriou ,&nbsp;Chrysa Charou ,&nbsp;Amalia Moutsopoulou","doi":"10.1016/j.bea.2023.100103","DOIUrl":"10.1016/j.bea.2023.100103","url":null,"abstract":"<div><p>Silicon nitride (Si₃N₄) is a well-known bio-ceramic that is widely used for medical and healthcare purposes, due to its biocompatibility and superior chemical, physical and mechanical properties, which make it suitable for implants. Due to its unique features, examining its efficiency as a cost-effective reinforcement agent for thermoplastics in material extrusion (MEX) Additive Manufacturing (AM) seems promising for the development of composites for biomedical applications. The mainstream thermoplastic in MEX AM is the biodegradable and biocompatible Polylactic Acid (PLA). Herein, a biomedical grade PLA was used as a matrix for Si₃N₄ nanopowder in various filler loadings. Filaments were prepared with melt extrusion, whereas MEX 3D printing was engaged to prepare specimens for mechanical evaluation, according to standardized tests. The effect of the Si₃N₄ nanoparticles loading and its optimization was carried out by means of fifteen (15) different tests. The nanocomposites were fully characterized with Raman, Thermogravimetric Analysis, and Scanning Electron Microscopy, among others. Aspects of the process, such as rheology and processability, were also assessed and quantified. A more than 40% increase in both flexural and tensile strength of the samples was found, proving the hypothesis for the effectiveness of Si₃N₄ nanoparticles as a compelling alternative reinforcement agent in MEX AM of biomedical PLA-based parts.</p></div>","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"6 ","pages":"Article 100103"},"PeriodicalIF":0.0,"publicationDate":"2023-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42907293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Static Strength Analysis on Steel Structure of Locomotive Cooling and Design Explorer Optimization","authors":"Meng Zhao","doi":"10.26855/ea.2023.06.016","DOIUrl":"https://doi.org/10.26855/ea.2023.06.016","url":null,"abstract":"With the comprehensive development of diesel locomotive and the improvement of running speed, the design of locomotive cooling system get more attention, the basic is to ensure that the strength of the structure in order to make locomotive's operation safe and reliable. This paper establish cooling steel structure finite element model with parametric method, and gets static strength results of the structure under different conditions. In order to make the structure satisfy the standard of intensity and shorten the design cycle, putting the design parameters and the extract command of equivalent stress into the export file of Hyper Mesh, using Workbench Design Explorer modules with experimental design method, based on Monte-Carlo method simulating sampling points, and fitting for response surface between the Design parameters and target parameters. Setting structure’s optimization algorithm and then the program automatically calculates the candidate de-sign points. After those design points are determined, it needs to calculate again, steel structure meets the design requirements of strength criteria in locomotive running.","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"55 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83531158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis on Risks and Preventive Measures of Overseas Highway Engineering: Taking Bolivia Project as an Example","authors":"Ying Pan, Jun Dong, Likuan Tian","doi":"10.26855/ea.2023.06.024","DOIUrl":"https://doi.org/10.26855/ea.2023.06.024","url":null,"abstract":"Under the Belt and Road Initiative, the pace of Chinese enterprises to explore overseas markets obviously quickens, and the international project contracting business has been maintaining rapid growth. At the same time, series of issues have brought the unprecedented impacts on human society, such as the scientific and technological revolution, the industrial revolution, climate change, etc. With more and more risk factors in the international project contracting market, the uncertainties faced by Chinese enterprises \"going global\" to carry out international business are increasing. Based on the \"the Two-San Project\" and \"the Yukumo Project\" being implemented by China Construction Group in Bolivia, the paper focuses on the internal and external risks, involved in the development of highway engineering projects. The various risk factors will be explained in detail so as to provide reference for the smooth implementation of the road projects under construction and the road projects to enter Bolivia in the future.","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73026522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discussion on the Difficulties and Countermeasures of Steel Structure Construction Technology in Building Engineering","authors":"Wei Sun","doi":"10.26855/ea.2023.06.019","DOIUrl":"https://doi.org/10.26855/ea.2023.06.019","url":null,"abstract":"","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"175 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77471897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Assessment of Water Conservancy Projects Based on Portfolio Empowerment","authors":"Hung Nguyen","doi":"10.26855/ea.2023.06.015","DOIUrl":"https://doi.org/10.26855/ea.2023.06.015","url":null,"abstract":"Water is the source of ecology, the foundation of ecology, and indispensable in the life and development of human society. Water conservancy is an important infrastructure in China, an indispensable primary condition for modern agricultural construction, an irreplaceable basic support for economic and social development, and an inseparable guarantee system for the improvement of the ecological environment. Water conservancy projects have always been key projects in China, playing an important role in ecological civilization construction and flood control power generation. However, due to the complexity of influencing factors, construction problems are becoming increasingly serious. In view of this, a risk evaluation system composed of different indicators is established, and AHP and entropy weight method are combined to determine the weight of each risk factor. The results show that the overall human risk has the most significant impact, accounting for the first proportion, and the gap between other factors is small. This shows that the proposed method can effectively analyze the project risks, promote the development of water conservancy projects, and better reduce the risks in water conservancy construction.","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87037032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress on Prefabricated Concrete Shear Wall","authors":"Gang Zhang, Jian Liu, Ting Xiong, Chun-Guang Zeng","doi":"10.26855/ea.2023.06.021","DOIUrl":"https://doi.org/10.26855/ea.2023.06.021","url":null,"abstract":"Prefabricated buildings have the advantages of high efficiency, a short construction period, high quality, and green environmental protection, making them the development trend and representatives of construction industrialization in the construction industry. Prefabricated buildings are also considered the future direction of the construction industry. Among various types of structures, the prefabricated shear wall structure has rapidly developed due to its weight advantages and various other benefits. It was the most mature and widely used prefabricated concrete structure. Numerous studies on prefabricated shear wall structures have been carried out in the United States and other countries to further promote the development of this structure. The connection mode of the prefabricated shear wall structure greatly influences its structural performance. It is necessary to ensure a reliable connection both between the precast wall panel and other components and among the components themselves to optimize the structure's performance. The current study introduces the development status of precast concrete structures and presents its research results. It also reviews the seismic performance, main connections, and design methods of precast concrete shear wall structures, offering valuable insights for the research and application of such structures.","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87297123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on New Cold Land Resource Recycling Village Residence—Take Shenyang Gulazi Village as an Example","authors":"D. Bu, E. Li","doi":"10.26855/ea.2023.06.023","DOIUrl":"https://doi.org/10.26855/ea.2023.06.023","url":null,"abstract":"","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81501203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on Distributed Storage Technology for Big Data","authors":"Zhenyao Duan","doi":"10.26855/ea.2023.06.020","DOIUrl":"https://doi.org/10.26855/ea.2023.06.020","url":null,"abstract":"With the widespread popularity of mobile Internet and the rapid development of Internet technology, a large number of new applications have emerged in the network, and the amount of data generated by these applications has shown an amazing explosive growth, and people are deeply aware of the huge value contained in these huge data. The term \"big data\" is widely used in various industries.\" With the continuous development of emerging fields such as artificial intelligence, machine learning, and user profiling, the term \"big data\" has been widely used to describe the amount of data and has become an indispensable support force in these fields. Cloud storage, as an emerging data service approach, has been widely used among various business systems in recent years. With the booming development of cloud storage technology, its performance is also improving by leaps and bounds, along with the rapid progress of cloud computing technology. At present, cloud storage technologies are mainly divided into two types of distributed computing models based on virtualization platforms and centralized architectures based on file systems. The purpose of this paper is to study the application of distributed database technology in the big data environment in order to achieve its continuous optimization in the real environment, so as to better serve the daily life of human beings.","PeriodicalId":72384,"journal":{"name":"Biomedical engineering advances","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73751090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}