Archives of rehabilitation research and clinical translation最新文献

{"title":"Defining Trajectories of Linguistic, Cognitive-Communicative, and Quality of Life Outcomes in Aphasia: Longitudinal Observational Study Protocol","authors":"Leora R. Cherney PhD , Allan J. Kozlowski PhD , Andrea A. Domenighetti PhD , Marwan N. Baliki PhD , Mary J. Kwasny ScD , Allen W. Heinemann PhD","doi":"10.1016/j.arrct.2024.100339","DOIUrl":"10.1016/j.arrct.2024.100339","url":null,"abstract":"<div><h3>Objective</h3><p>To describe the trajectories of linguistic, cognitive-communicative, and health-related quality of life (HRQOL) outcomes after stroke in persons with aphasia.</p></div><div><h3>Design</h3><p>Longitudinal observational study from inpatient rehabilitation to 18 months after stroke.</p></div><div><h3>Setting</h3><p>Four US mid-west inpatient rehabilitation facilities (IRFs).</p></div><div><h3>Participants</h3><p>We plan to recruit 400 adult (older than 21 years) English speakers who meet the following inclusion criteria: (1) Diagnosis of aphasia after a left-hemisphere infarct confirmed by CT scan or magnetic resonance imaging (MRI); (2) first admission for inpatient rehabilitation due to a neurologic event; and (3) sufficient cognitive capacity to provide informed consent and participate in testing. Exclusion criteria include any neurologic condition other than stroke that could affect language, cognition or speech, such as Parkinson's disease, Alzheimer's disease, traumatic brain injury, or the presence of right-hemisphere lesions.</p></div><div><h3>Interventions</h3><p>Not applicable.</p></div><div><h3>Main Outcome Measures</h3><p>Subjects are administered a test battery of linguistic, cognitive-communicative, and HRQOL measures. Linguistic measures include the Western Aphasia Battery-Revised and the Apraxia of Speech Rating Scale. Cognitive-communicative measures include the Communication Participation Item Bank, Connor's Continuous Performance Test-3, the Communication Confidence Rating Scale for Aphasia, the Communication Effectiveness Index, the Neurological Quality of Life measurement system (Neuro-QoL) Communication short form, and the Neuro-QoL Cognitive Function short form. HRQOL measures include the 39-item Stroke & Aphasia Quality of Life Scale, Neuro-QoL Fatigue, Sleep Disturbance, Depression, Ability to Participate in Social Roles & Activities, and Satisfaction with Social Roles & Activities tests, and the Patient-Reported Outcome Measurement and Information System 10-item Global Health short form. The test battery is administered initially during inpatient rehabilitation, and at 3-, 6-, 12-, and 18-months post-IRF discharge. Biomarker samples are collected via saliva samples at admission and a subgroup of participants also undergo resting state fMRI scans.</p></div><div><h3>Results</h3><p>Not applicable.</p></div><div><h3>Conclusions</h3><p>This longitudinal observational study will develop trajectory models for recovery of clinically relevant linguistic, cognitive-communicative, and quality of life outcomes over 18 months after inpatient rehabilitation. Models will identify individual differences in the patterns of recovery based on variations in personal, genetic, imaging, and therapy characteristics. The resulting models will provide an unparalleled representation of recovery from aphasia resulting from stroke. This improved understanding of recovery will enable clinicians to better tailor and","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100339"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000296/pdfft?md5=f08452b2605844cdde477fcfd7c18315&pid=1-s2.0-S2590109524000296-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights on Telecommunication Use by Rehabilitation Therapists Before, During, and Beyond COVID-19","authors":"Michael J. Sobrepera PhD ,&nbsp;Julie Elfishawy ,&nbsp;Anh T. Nguyen ,&nbsp;Laura P. Prosser PhD ,&nbsp;Michelle J. Johnson PhD","doi":"10.1016/j.arrct.2024.100326","DOIUrl":"10.1016/j.arrct.2024.100326","url":null,"abstract":"<div><h3>Objective</h3><p>To determine if the use of telerehabilitation among rehabilitation therapists during the first 11 months of the COVID-19 pandemic increased, if therapists’ identified plans to continue use after the pandemic, and to understand challenges that therapists face in using telerehabilitation, and to evaluate viable use-cases for telerehabilitation.</p></div><div><h3>Design</h3><p>A survey was conducted among clinicians containing questions about tools being used before, during, and after (planned) COVID-19. Statistical analysis was conducted to evaluate the increase in actual usage of telerehabilitation during the pandemic and planned usage after the pandemic.</p></div><div><h3>Setting</h3><p>The study was survey-based and conducted remotely via online distribution.</p></div><div><h3>Participants</h3><p>387 participants (90.2% women) with an average age of 40.1 years participated in the survey and satisfied selection criteria. On average, they practiced for 14.8 years.</p></div><div><h3>Main Outcome Measures</h3><p>No interventions were made. Survey item results were used for analysis.</p></div><div><h3>Results</h3><p>Therapists used telerehabilitation more frequently during COVID-19 as compared with before COVID-19. Therapist use of video calls more than tripled (288.89% increase) during COVID-19. Speech therapists were far more likely to adopt telerehabilitation than physical therapists or occupational therapists. 18.9% of therapists planned to use video-based remote communication with patients after COVID-19. 31% of therapists who had not previously used telerehabilitation prior to the pandemic anticipated using it post-pandemic. Most therapists (88%) believed that discussion-based activities could be done remotely.</p></div><div><h3>Conclusions</h3><p>COVID-19 has affected the way therapists interact with patients. These changes may have lasting effect on patient interactions and a perceived potential for future use of telerehabilitation is evident. Therapists who had already made use of remote communication had more optimistic outlooks on the future utility of these mediums, indicating that exposure favors future use. Therapists anticipate a potential increase in utilization of Video-Based Telerehabilitation post-pandemic but have faced and expect to face challenges in use of telerehabilitation. While disparities and obstacles to access pose challenges, the progress made during COVID-19 is promising.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100326"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000090/pdfft?md5=6bcb421079fa1d170ad947e925b83789&pid=1-s2.0-S2590109524000090-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139821611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Inpatient Rehabilitation Functional Outcomes and Disposition After Liver Transplant","authors":"Meghan E. Willoughby BS ,&nbsp;Jacob L. Ramsey-Morrow MD ,&nbsp;Kyle A. Littell MD ,&nbsp;Flora M. Hammond MD","doi":"10.1016/j.arrct.2024.100332","DOIUrl":"10.1016/j.arrct.2024.100332","url":null,"abstract":"<div><h3>Objective</h3><p>To describe the outcomes (change in functional independence and discharge disposition) of patients who after liver transplantation received acute inpatient rehabilitation in a freestanding rehabilitation hospital.</p></div><div><h3>Design</h3><p>A retrospective chart review was conducted of patients admitted to an acute inpatient rehabilitation hospital within 6 months of undergoing liver transplantation between January 2014 and December 2018. Change in function from rehabilitation admission to discharge was measured using FIM Change and FIM Efficiency.</p></div><div><h3>Setting</h3><p>A freestanding rehabilitation hospital.</p></div><div><h3>Participants</h3><p>107 patients who underwent acute inpatient rehabilitation at a freestanding rehabilitation hospital within 6 months after liver transplantation who met inclusion criteria (N=107). Most were men (71.96%), and the mean age of the patient population was 62.15 years.</p></div><div><h3>Interventions</h3><p>Acute inpatient rehabilitation consisting of at least 3 hours of therapy 5 days a week split between physical therapy, occupational therapy, and speech language pathology services.</p></div><div><h3>Main Outcome Measure</h3><p>FIM Change, FIM Efficiency, Discharge Disposition.</p></div><div><h3>Results</h3><p>Participants were found to have statistically significant positive FIM Change (<em>P</em>&lt;.00001) and FIM Efficiency (<em>P</em>&lt;.00001). The mean FIM Change and Efficiency were 35.7±11.8 and 2.4±1.0, respectively. 83.2% (n = 89) were ultimately discharged to the community.</p></div><div><h3>Conclusion</h3><p>Acute inpatient rehabilitation provides patients who have received a liver transplant with the opportunity to measurably improve their function and independence, with most patients being able to return home.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100332"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000223/pdfft?md5=b59aa4376e8377880209ed808087fd53&pid=1-s2.0-S2590109524000223-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140274123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Depression Symptoms and Disability Outcomes in Older Adults at Risk of Mobility Decline","authors":"Patricia M. Bamonti PhD ,&nbsp;Meaghan A. Kennedy MD, MPH ,&nbsp;Rachel E. Ward PhD, MPH ,&nbsp;Thomas G. Travison PhD ,&nbsp;Jonathan F. Bean MD, MPH","doi":"10.1016/j.arrct.2024.100342","DOIUrl":"https://doi.org/10.1016/j.arrct.2024.100342","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the association between depression symptoms and physical functioning and participation in daily life over 2 years in older adults at risk of mobility decline.</p></div><div><h3>Design</h3><p>A secondary analysis of 2-year observational data from the Boston Rehabilitative Impairment Study of the Elderly.</p></div><div><h3>Setting</h3><p>Nine primary care clinics within a single health care system.</p></div><div><h3>Participants</h3><p>Participants (N=432; mean age ± SD, 76.6±7.0y; range, 65-96y; 67.7% women) were community-dwelling adults (&gt;65y) at risk of mobility decline.</p></div><div><h3>Interventions</h3><p>Not applicable.</p></div><div><h3>Main Outcome Measures</h3><p>Secondary data analyses of the Late Life Function and Disability Instrument (primary outcome), Short Physical Performance Battery (secondary outcome), and Patient Health Questionnaire-9 (PHQ-9) (predictor). Measures were administered at baseline, 12 months, and 24 months. Participants completed a self-report survey asking about 16 medical comorbidities, and demographic information was collected at baseline.</p></div><div><h3>Results</h3><p>Participants had an average ± SD PHQ-9 score of 1.3±3.1, ranging from 0 to 24 at baseline. Twenty-nine percent of participants reported a history of depression. Greater depression symptoms were associated with lower physical functioning (unstandardized beta [<em>B</em>]=−0.14, SE=0.05, P=.011) and restricted participation (frequency subscale: <em>B</em>=−0.21, SE=0.11, <em>P</em>=.001; limitation subscale: <em>B</em>=−0.45, SE=0.04, <em>P</em>&lt;.001) cross-sectionally over 2 years. PHQ-9 was not significantly associated with the rate of change in Late Life Function and Disability Instrument score over 2 years.</p></div><div><h3>Conclusions</h3><p>Treating depression in primary care may be an important strategy for reducing the burden of functional limitations and participation restrictions at any 1 time. Further research is needed on treatment models to cotarget depression and physical functioning among at-risk older adults.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100342"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000326/pdfft?md5=15a90e5cf7d3c2332924b7721d6567f9&pid=1-s2.0-S2590109524000326-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Hip and Knee Strengthening Compared With Knee Strengthening for Individuals With Lateral Patellar Dislocation: A Single-blind, Superiority, Randomized Controlled Trial","authors":"Lucas Simões Arrebola PhD ,&nbsp;Toby O. Smith PhD ,&nbsp;Vanessa Gonçalves Coutinho de Oliveira MSc ,&nbsp;Pedro Rizzi de Oliveira MSc ,&nbsp;Paloma Yan Lam Wun ,&nbsp;Rogério Teixeira de Carvalho PhD ,&nbsp;Carlos Eduardo Pinfildi PhD","doi":"10.1016/j.arrct.2024.100334","DOIUrl":"10.1016/j.arrct.2024.100334","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate whether a combined hip and knee muscle strengthening program is superior to a knee strengthening program for people after lateral patellar dislocation (LPD).</p></div><div><h3>Design</h3><p>Single-blind, superiority, randomized controlled trial with 48 weeks follow-up.</p></div><div><h3>Setting</h3><p>Physiotherapy out-patient clinic.</p></div><div><h3>Participants</h3><p>Forty individuals aged 16 or older, with a history of non-traumatic LPD were randomized to a knee-based strengthening (KBSG) or quadriceps and hip strengthening exercise (HQSG) program (N=40). Inclusion criteria included a positive apprehension sign, pain on palpation along the medial retinaculum, and J sign. Exclusion criteria included restricted range of motion (&lt;90° knee flexion), and traumatic or postsurgical LPD.</p></div><div><h3>Interventions</h3><p>Concealed randomization was performed using random permuted blocks of size 4. Individuals received their corresponding exercise program according to randomization and group allocation: knee-based strengthening (n=20) or combined hip and quadriceps strengthening (n=20) twice weekly for 8 weeks over 16 appointments.</p></div><div><h3>Main Outcome Measures</h3><p>Primary outcome was the Lysholm Knee Score. Secondary outcomes included Numerical Pain Ratings Scale (NPRS) at rest and during effort, Norwich Patellar Instability Score (NPIS), Kujala Anterior Knee Pain Scale (AKPS), Lower Extremity Functional Scale (LEFS), 4 domains of the WHOQOL-Bref, and recurrence rate. Patient-reported outcome measures were assessed from the baseline to 48 weeks. Assessments were performed by a physiotherapist who was blinded to the group allocation. Data were analyzed by using a repeated-measures ANOVA model with Tukey's post hoc test after an intention-to-treat principle.</p></div><div><h3>Results</h3><p>At the primary time-point of 8 weeks, there were no substantial between-group differences in the Lysholm Knee Score: mean difference=-6.8 (95% CI -14.3 to 3.7); NPIS: mean difference=23.5 (95% CI 5.6 to 41.3); AKPS: mean difference=-1.54 (95% CI -8.6 to 5.6), NPRS at rest and during effort (mean difference=0.32 (95% CI -0.37 to 1); and mean difference=0.68 (95% CI -0.9 to 1.86); LEFS mean difference=-1.08 (95% CI -5.9 to 2.4), WHOQOL-Bref domains (physical health: mean difference=-0.12, (95% CI -1.26 to 1.02); psychological: mean difference=-0.32 (95% CI -2.04 to 1.4); social relations: mean difference=-0.7 (95% CI -2.2 to 0.82); environment: mean difference=0.44 (95% CI -1 to 1.9), and recurrence rate (<em>P</em>=.69).</p></div><div><h3>Conclusion</h3><p>This study indicates that combined hip and knee muscle strengthening is not superior to knee-based strengthening for LPD treatment. The limitations stemming from the underpowered nature of the trial must be acknowledged, concerning the potential oversight of moderate intervention effects.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100334"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000247/pdfft?md5=3f3c71208d1d61d4107561ecb68ca5f4&pid=1-s2.0-S2590109524000247-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140268902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adapting the Multiple Sclerosis Functional Composite for Telehealth Administration Using Videoconference Delivery: Methodological Considerations and Interrater Reliability","authors":"Toni Van Denend OTD, OTR/L ,&nbsp;Virgil Mathiowetz PhD, OT, FAOTA ,&nbsp;Katharine Preissner EdD, OTR/L, FAOTA ,&nbsp;Francois Bethoux MD ,&nbsp;Marcia Finlayson PhD, OTR, OT Reg (Ont) ,&nbsp;Tanya Packer PhD OTReg (NS) ,&nbsp;Setareh Ghahari PhD, OT Reg (Ont) ,&nbsp;Matthew Plow PhD","doi":"10.1016/j.arrct.2024.100337","DOIUrl":"10.1016/j.arrct.2024.100337","url":null,"abstract":"<div><h3>Objective</h3><p>To describe the adaptations made and to examine interrater reliability and feasibility of administering a telehealth version of the Multiple Sclerosis Functional Composite (tele-MSFC).</p></div><div><h3>Design</h3><p>The Multiple Sclerosis Functional Composite (MSFC) is a commonly used, in-person clinical outcome assessment. It is composed of the timed 25-Foot Walk Test (T25FWT), Nine-Hole Peg Test (NHPT), and Paced Auditory Serial Addition Test (PASAT). The MSFC was adapted for videoconference administration as part of a larger clinical trial. One of the adaptations included administering a timed 12.5-Foot Walk Test (T12.5FWT) for participants who did not have adequate space in their homes for the T25FWT. Participants, examiners, and raters completed surveys online about their satisfaction and experience with tele-MSFC.</p></div><div><h3>Setting</h3><p>Participants underwent the tele-MSFC in their homes using a laptop or smartphone while examiners scored the tele-MSFC in real-time at a remote location.</p></div><div><h3>Participants</h3><p>Community-dwelling adults (n=61) with mild-to-moderate multiple sclerosis (MS) symptoms.</p></div><div><h3>Interventions</h3><p>Not applicable.</p></div><div><h3>Main Outcome Measure</h3><p>Tele-MSFC.</p></div><div><h3>Results</h3><p>Intraclass correlation coefficients (ICC) assessed interrater reliability between the examiner and 2 independent raters who later scored a recording of the tele-MSFC. Interrater reliability was excellent (ICC&gt;0.90) for all tests, including the T12.5FWT. Participants were highly satisfied with tele-MSFC. However, challenges included adequate space for T25FWT, technical difficulties, and safety and privacy considerations of individuals with moderate impairments who were requested to have their caregivers present during testing.</p></div><div><h3>Conclusion</h3><p>The tele-MSFC is reliable and feasible to administer with adaptations for community-dwelling adults with mild to moderate MS symptoms. Further validation of T12.5FWT is needed.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100337"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000272/pdfft?md5=a7ad8cd2b8b89c417b7aef4e832bdc16&pid=1-s2.0-S2590109524000272-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140401976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rehabilitation Professionals’ Perspectives on Human Rights, Disability, and Science: A Qualitative Study","authors":"Anne M. Bryden PhD, OTR/L ,&nbsp;Kim D. Anderson PhD ,&nbsp;Brian Gran PhD, JD","doi":"10.1016/j.arrct.2024.100336","DOIUrl":"10.1016/j.arrct.2024.100336","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the attitudes and knowledge of rehabilitation professionals concerning human rights within the context of disability, science, and technology access.</p></div><div><h3>Design</h3><p>A qualitative study using in-depth semi-structured interviews.</p></div><div><h3>Setting</h3><p>A large, urban, academically-affiliated rehabilitation research center.</p></div><div><h3>Participants</h3><p>We conducted semi-structured interviews with rehabilitation professionals who specialize in spinal cord injury (SCI) care, including 6 physicians, 3 physical therapists, 2 occupational therapists, 2 nurses, 1 rehabilitation engineer, and 1 rehabilitation psychologist (N=15). Participants were purposively recruited through e-mail letters to members of the American Spinal Injury Association. Efforts were made to recruit a diverse cohort of rehabilitation professionals based on profession, sex, age, and race. Interviews were conducted in person during the 2018 annual meeting or by phone after the meeting.</p></div><div><h3>Interventions</h3><p>Not applicable.</p></div><div><h3>Main Outcome Measures</h3><p>Interviews were recorded, transcribed verbatim, and coded to identify emerging themes within and across participants’ content.</p></div><div><h3>Results</h3><p>Primary findings show that most respondents were unaware of disability-relevant human rights doctrine. None was aware of the right to science as articulated in Article 15 of the International Covenant on Economic, Social, and Cultural Rights. Only 2 respondents had previously considered injustices experienced by their clients as human rights violations, yet nearly all were intrigued by framing access difficulties within the right to science paradigm. Overall, participants reported they would find value in implementing human rights in their work.</p></div><div><h3>Conclusions</h3><p>Rehabilitation professionals are receptive to a human rights framework. Further research is needed to identify actionable steps for implementing principles of human rights to increase access to technology by individuals with SCI.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100336"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000260/pdfft?md5=a00b4c821e67f90d0f96fb330cc0a814&pid=1-s2.0-S2590109524000260-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140406281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relations Between Cardiorespiratory Fitness and Cognition in Older Adults With Amnestic Mild Cognitive Impairment From the Aerobic Exercise and Cognitive Training (ACT) Trial: Sex Differences","authors":"Fang Yu PhD, RN ,&nbsp;Dereck Salisbury PhD ,&nbsp;Keenan A. Pituch PhD ,&nbsp;Feng Vankee Lin PhD","doi":"10.1016/j.arrct.2024.100341","DOIUrl":"10.1016/j.arrct.2024.100341","url":null,"abstract":"<div><h3>Objective</h3><p>To examine the associations of cardiorespiratory fitness with executive function, episodic memory, and global cognition and sex differences in these associations in community-dwelling older adults with amnestic mild cognitive impairment.</p></div><div><h3>Design</h3><p>A cross-sectional study using baseline data from the aerobic exercise and cognitive training (ACT) trial.</p></div><div><h3>Setting</h3><p>The ACT trial conducted exercise testing in an exercise laboratory and data collections in a research facility.</p></div><div><h3>Participants</h3><p>ACT trial participants were recruited through referrals, registries, exhibits, flyers, media, and advertisements and screened for eligibility. To be eligible for this study, ACT enrollees needed complete data on all study variables. Among 146 ACT enrollees, 142 met eligibility for this study (N=142).</p></div><div><h3>Interventions</h3><p>None.</p></div><div><h3>Main Outcome Measures</h3><p>Cardiorespiratory fitness was measured as peak oxygen consumption (V<span>o</span>_2peak) with a peak cycle-ergometer test, executive function with the EXAMINER, episodic memory with the Brief Visuospatial Memory Test-Revised, and global cognition with Montreal Cognitive Assessment.</p></div><div><h3>Results</h3><p>The average age of the sample was 73.8±5.8 years with 16.9±2.9 years of education, with 87.3% White, 51.4% men, and 69.7% married. After controlling for covariates, V<span>o</span>_2peak was significantly related to executive function (<em>b</em>=.037, standard error [SE]=0.015, <em>P</em>=.0154, semipartial [<em>sr</em>] correlation coefficient=.239) and episodic memory (<em>b</em>=.590, SE=0.226, <em>P=</em>.0102, <em>sr</em>=.216), but not global cognition (<em>b</em>=.074, SE=0.055, <em>P=</em>.1837, <em>sr</em>=.125). For men, V<span>o</span>_2peak was significantly associated with executive function (<em>b</em>=.063, SE=0.024, <em>P</em>=.0099, <em>r</em>=.430) and episodic memory (<em>b</em>=1.088, SE=0.312, <em>P</em>=.0009, <em>r</em>=.382).</p></div><div><h3>Conclusions</h3><p>Our findings show that V<span>o</span>_2peak was associated with executive function and episodic memory in the overall sample and in men. Future studies can examine the longitudinal relations between cardiorespiratory fitness and cognition.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100341"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000314/pdfft?md5=904480054dec6c0688927228a7db0cf5&pid=1-s2.0-S2590109524000314-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140793639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Submaximal, Low-Dose Eccentric vs Traditional Cycling Exercise: Reduced Oxygen Uptake and Pulmonary Artery Pressure Assessed by Echocardiography in Healthy Middle-aged Adults. A Randomized Controlled, Crossover Trial","authors":"Julian Müller MSc ,&nbsp;Meret Bauer MD ,&nbsp;Simon R. Schneider PhD ,&nbsp;Laura Mayer MD ,&nbsp;Anna Titz MD ,&nbsp;Nico Sturzenegger ,&nbsp;Esther I. Schwarz MD ,&nbsp;Christoph Bauer PhD ,&nbsp;Ekkehard Grünig MD ,&nbsp;Malcolm Kohler MD ,&nbsp;Mona Lichtblau MD ,&nbsp;Silvia Ulrich MD","doi":"10.1016/j.arrct.2024.100331","DOIUrl":"10.1016/j.arrct.2024.100331","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the ventilatory and circulatory differences between eccentric (ECC) and concentric (CON) cycling exercise at submaximal, low-dose intensity from onset to end-exercise in healthy middle-aged participants.</p></div><div><h3>Design</h3><p>Randomized controlled crossover trial.</p></div><div><h3>Setting</h3><p>The participants underwent 1 ECC and 1 CON test according to stepwise incremental exercise protocols at identical, submaximal intensities. Breath-by-breath analyses of ventilatory gas exchange and echocardiography were used to assess cardiopulmonary function during exercise.</p></div><div><h3>Participants</h3><p>24 healthy middle-aged, untrained participants (14 women, 10 men, 50±14 years) were included.</p></div><div><h3>Interventions</h3><p>1 ECC and 1 CON test at submaximal intensities.</p></div><div><h3>Main Outcome Measure</h3><p>The main outcome was oxygen uptake (V'O₂).</p></div><div><h3>Results</h3><p>The V'O₂ increase was reduced by -422 mL/min (-52%, 95% confidence interval: -513 to -292, <em>P</em>&lt;.001) during ECC, as well as the ventilatory drive. Echocardiographic parameters, heart rate (-14%), cardiac output (-21%), stroke volume (-15%), and pulmonary artery pressure by tricuspid regurgitation pressure gradient (TRPG) (-26%) were also significantly reduced during ECC compared with CON at identical intensities. Participants reported significantly less dyspnea and unchanged perceived leg fatigue in ECC.</p></div><div><h3>Conclusion</h3><p>ECC was well tolerated, and significant reductions were observed in V'O₂, ventilation, and right ventricular load compared with CON, even at low intensity levels. This study, conducted on healthy middle-aged participants, did not raise concerns that would hinder further investigation of the effects of ECC in patients with severely limited cardiopulmonary disease, and it calls for further research on this topic.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 2","pages":"Article 100331"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590109524000211/pdfft?md5=4a78afc8c2f7a78562f1645d9e79c901&pid=1-s2.0-S2590109524000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140281661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Dizziness Impact Measures of Positional, Functional, and Emotional Status Were Supported for Reliability, Validity, and Efficiency","authors":"Daniel Deutscher PT, MScPT, PhD ,&nbsp;Deanna Hayes PT, DPT, MS ,&nbsp;Michael A. Kallen PhD, MPH","doi":"10.1016/j.arrct.2024.100320","DOIUrl":"10.1016/j.arrct.2024.100320","url":null,"abstract":"<div><h3>Objective</h3><p>To calibrate the 25 items from the Dizziness Handicap Inventory (DHI) patient-reported outcome measure (PROM), using item response theory (IRT), into 1 or more item banks, and assess reliability, validity, and administration efficiency of scores derived from computerized adaptive test (CAT) or short form (SF) administration modes.</p></div><div><h3>Design</h3><p>Retrospective cohort study.</p></div><div><h3>Setting</h3><p>Outpatient rehabilitation clinics.</p></div><div><h3>Participants</h3><p>Patients (N=28,815; women=69%; mean age [SD]=60 [18]) included in a large national dataset and assessed for dizziness-related conditions who responded to all DHI items at intake.</p></div><div><h3>Interventions</h3><p>Not applicable.</p></div><div><h3>Main Outcome Measures</h3><p>IRT model assumptions of unidimensionality, local item independence, item fit, and presence of differential item functioning (DIF) were evaluated. Generated scores were assessed for reliability, validity, and administration efficiency.</p></div><div><h3>Results</h3><p>Patients were treated in 976 clinics from 49 US states for either vestibular-, brain injury-, or neck-related impairments. Three unidimensional item banks were calibrated, creating 3 distinct PROMs for Dizziness Functional Status (DFS, 13 items), Dizziness Positional Status (DPS, 4 items), and Dizziness Emotional Status (DES, 6 items). Two items did not fit into any domain. A DFS-CAT and a DFS 7-item SF were developed. Except for 2 items by age groups and 1 item by main impairment, no items were flagged for DIF; DIF impact was negligible. Median reliability estimates were 0.91, 0.72, and 0.79 for the DFS, DPS, and DES, respectively. Scores discriminated between patient groups in clinically logical ways and had a large effect size (&gt;0.8), with acceptable floor and ceiling effects (&lt;15%), except for a floor effect for DPS (20.4%). DFS-CAT scores were generated using a median of 8 items; they correlated highly with full-bank scores (<em>r</em>=0.99).</p></div><div><h3>Conclusion</h3><p>The 3 dizziness impact PROMs demonstrated moderate to high reliability, were valid, and highly responsive to change; thus, they are suitable for research and routine clinical administration.</p></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"6 1","pages":"Article 100320"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S259010952400003X/pdfft?md5=80841769b40d76d04c4d9a5ff5094b93&pid=1-s2.0-S259010952400003X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139395082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}