Archives of rehabilitation research and clinical translation最新文献

{"title":"Author Response to Letter to the Editor: Evaluation of Clemastine Effects on Clinical and Electrodiagnostic Parameters in Carpal Tunnel Syndrome (CTS) Patients: A Preliminary Placebo-Controlled Double Blind RCT","authors":"Gholamreza Raissi MD, Tannaz Ahadi MD, Kamyar Kazemi MD, Seyed Pezhman Madani MD, Simin Sajadi MD, Hosna Soleymanzadeh MSc, Negar Kariznoee PharmD","doi":"10.1016/j.arrct.2026.100628","DOIUrl":"10.1016/j.arrct.2026.100628","url":null,"abstract":"","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100628"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Location-Specific Disruption of the Body Schema in Chronic Low Back Pain","authors":"Paul Teillet,&nbsp;Lucette Toussaint PhD,&nbsp;Romain David MD,&nbsp;Rémi Cabirol MD,&nbsp;Maxime Billot PhD,&nbsp;Romain Tisserand PhD","doi":"10.1016/j.arrct.2026.100666","DOIUrl":"10.1016/j.arrct.2026.100666","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate whether chronic low back pain (CLBP) involves location-specific or more general body schema alterations, thereby helping to determine whether location-specific tasks may improve assessment of sensorimotor alterations and/or rehabilitation strategies for CLBP patients. And, secondarily, to examine whether pain intensity is associated with the extent of body schema alterations.</div></div><div><h3>Design</h3><div>Between-subject comparative study with age- and sex-matched groups.</div></div><div><h3>Setting</h3><div>This study was conducted at a University Hospital.</div></div><div><h3>Participants</h3><div>Nineteen patients with CLBP and 19 healthy control participants matched for age and sex.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>Body schema alterations were assessed using response time and accuracy of implicit motor imagery (IMI; ie, laterality judgment tasks) involving the painful location (low back) and a nonpainful location (hand). In CLBP patients, average pain intensity was assessed using numerical rating scales.</div></div><div><h3>Results</h3><div>Compared with healthy adults, CLBP patients showed longer response time in the task involving the painful location (low back) but no difference in the task involving a nonpainful location (hand). No significant correlation was found between pain intensity and response time or accuracy.</div></div><div><h3>Conclusions</h3><div>CLBP seems associated with location-specific alterations of the body schema rather than being a generalized sensorimotor impairment. Consequently, this study highlights the value of location-specific tasks as tools for objectively identifying pain-related sensorimotor alterations and their potential to improve rehabilitation.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100666"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and Immediate Effects of Dynamic Exercise Using Mixed Reality for Balance Improvement in Older Adults and Individuals With Neurologic Disorders","authors":"Kazuki Ushizawa OTR, MS,&nbsp;Shintaro Uehara PT, PhD,&nbsp;Akiko Yuasa PT, PhD,&nbsp;Daisuke Matsuura MD, PhD,&nbsp;Yoshitaka Wada MD, PhD,&nbsp;Hirohisa Watanabe MD, PhD,&nbsp;Yohei Otaka MD, PhD","doi":"10.1016/j.arrct.2026.100636","DOIUrl":"10.1016/j.arrct.2026.100636","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the feasibility and immediate effects of dynamic exercise using mixed reality (MR), a technology that allows real-time interaction between physical surroundings and computer-generated virtual objects, in older adults and individuals with Parkinson’s disease and stroke.</div></div><div><h3>Design</h3><div>Prospective single-arm intervention study.</div></div><div><h3>Setting</h3><div>Rehabilitation ward in the hospital.</div></div><div><h3>Participants</h3><div>Thirty-one participants, including 10 community-dwelling older adults without neurologic or neuromuscular disorders (4 women; mean age, 70.4 y; SD, 3.0), 11 outpatients with Parkinson’s disease (4 women; mean age, 68.4 y; SD, 7.6), and 10 individuals with a stroke (3 women; mean age, 62.8 y; SD, 16.2) in a subacute rehabilitation ward were recruited.</div></div><div><h3>Interventions</h3><div>Participants performed MR-based exercise for approximately 20 minutes.</div></div><div><h3>Main Outcome Measures</h3><div>After exercise, participants rated their level of simulator sickness using the Simulator Sickness Questionnaire (SSQ). They further rated their enjoyment, continuation, exercise effectiveness, and fatigue using a Numerical Rating Scale. The Timed Up and Go test and Functional Reach Test were performed both before and after the exercise.</div></div><div><h3>Results</h3><div>The median SSQ-nausea, SSQ-oculomotor, SSQ-disorientation, and SSQ-total scores were 9.5, 7.6, 0.0, and 7.5, respectively, indicating a low likelihood of simulator sickness. The median Numerical Rating Scale scores for enjoyment, continuation, effectiveness, and fatigue were 8.0, 8.0, 7.5, and 2.0, respectively. The Timed Up and Go test in individuals with stroke and Functional Reach Test in older adults showed significant improvement after exercise (<em>P</em>&lt;.05).</div></div><div><h3>Conclusions</h3><div>Dynamic exercises with MR may be sufficiently feasible to perform balance exercises with less risk of simulator sickness, offering the potential to improve balance ability.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100636"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Guided Percutaneous Distal Biceps Tenotomy for Fixed Spastic Elbow Contracture in Cerebral Palsy: Case Report and Technical Note","authors":"Diego Hermoso de Mendoza Pi MD,&nbsp;Alfredo Rodríguez Pérez MD,&nbsp;Ana Meléndez Laborda MD,&nbsp;Pedro Ignacio Tejada Ezquerro MD,&nbsp;Ivan Gil de Sousa Duarte MD","doi":"10.1016/j.arrct.2026.100610","DOIUrl":"10.1016/j.arrct.2026.100610","url":null,"abstract":"<div><div>Fixed spastic elbow flexion contracture is a frequent and disabling problem in chronic upper motor neuron syndromes, including cerebral palsy (CP), in which sustained hypertonia and long-standing immobility may lead to musculotendinous shortening, skin breakdown, pain, and major hygiene and positioning limitations. We report a 63-year-old woman with severe spastic CP (Gross Motor Function Classification System Level V) presenting with a fixed left elbow flexion posture associated with antecubital maceration and caregiver burden. Multiple cycles of botulinum toxin type A failed to improve passive range of motion, and diagnostic nerve blocks, including a musculocutaneous nerve block, produced no gain in elbow extension, supporting a fixed contracture. The patient underwent ultrasound-guided percutaneous distal biceps tenotomy in an outpatient setting under local anesthesia using an 18-gauge Nokor needle, with real-time identification of adjacent neurovascular structures. Near-complete passive elbow extension was achieved immediately after the procedure. A localized hematoma was observed without compartment syndrome or ultrasound evidence of collection. At 6 months, range of motion improved from −90° to −30°, and resistance to passive movement decreased (Modified Ashworth Scale from 4 to 1). Two predefined Goal Attainment Scaling targets were met at follow-up (0 and +1), and the Patient Global Impression of Change indicated substantial improvement (+2). Ultrasound-guided percutaneous distal biceps tenotomy may represent a feasible, well-tolerated, minimally invasive option for selected patients with fixed spastic elbow contracture when dynamic spasticity is no longer modifiable, potentially improving care-related outcomes while avoiding conventional surgery in medically complex individuals.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100610"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequential Cryoneurolysis and Percutaneous Needle Tenotomy for Refractory Wrist Flexor Contracture: A Retrospective Case Series in Stroke and Spinal Cord Injury","authors":"Paul Winston MD,&nbsp;Hendrik Pepler BSc,&nbsp;Sophie Alexander BSc,&nbsp;Ibrahim Ali MD,&nbsp;Mahdis Hashemi MD","doi":"10.1016/j.arrct.2026.100630","DOIUrl":"10.1016/j.arrct.2026.100630","url":null,"abstract":"<div><div>Upper limb spasticity after stroke or spinal cord injury can lead to fixed wrist flexion contractures that limit hygiene, splinting, and functional positioning. Cryoneurolysis can effectively reduce wrist flexor spastic tone; however, when longstanding contracture is present, residual mechanical restriction often persists. Percutaneous needle tenotomy (PNT) offers a minimally invasive method to release structurally shortened musculotendinous units and restore passive mobility. In this retrospective case series, we describe the outcomes of wrist flexor PNT performed after prior cryoneurolysis in patients with refractory upper limb spasticity. Four adults with chronic upper limb spasticity secondary to stroke or spinal cord injury underwent wrist flexor cryoneurolysis followed by PNT for persistent contracture limiting passive range of motion (ROM). Passive wrist extension ROM and muscle tone were graded before and after intervention. Clinical rationale for transitioning from cryoneurolysis to PNT was qualitatively documented. Across all 4 cases, cryoneurolysis produced meaningful tone reduction; however, passive wrist extension remained limited due to fixed end-range contracture. After PNT, the patients demonstrated immediate and sustained gains in passive wrist extension ROM. Modified Ashworth Scale scores remained stable or demonstrated mild improvement posttenotomy, consistent with tone reduction achieved by preceding cryoneurolysis. No major adverse events were reported. Sequential use of cryoneurolysis followed by PNT may be effective for managing refractory wrist flexion contracture, where tone reduction alone is insufficient.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100630"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Disseminated Encephalomyelitis Presenting With Paraplegia and a Neurogenic Bladder: A Case Report and Brief Literature Review","authors":"Laura Longo MD,&nbsp;Giuseppina Bonfiglio MD,&nbsp;Rossella Longo MD","doi":"10.1016/j.arrct.2026.100642","DOIUrl":"10.1016/j.arrct.2026.100642","url":null,"abstract":"<div><div>Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated demyelinating disorder in children. While lower urinary tract dysfunction (LUTD) is estimated to affect up to 33% of patients, it is frequently overlooked in clinical reports, and specific rehabilitation strategies are still lacking. We describe a pediatric patient with ADEM presenting with paraplegia and an areflexic neurogenic bladder, managed with a structured rehabilitation protocol, including clean intermittent catheterization, afferent neuromodulation, and pelvic floor training. Progressive neurological and urinary recovery was achieved within 2 months. This case highlights the potential role of early multidisciplinary rehabilitation in promoting bladder recovery in ADEM.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100642"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward Automation of Motor Assessments in Stroke: Proof-of-Concept Model to Interpret Balance and Gait in Patients With Stroke","authors":"Yee Mah PhD,&nbsp;Vassilios Tahtis MRes,&nbsp;Abigail Beddard BSc,&nbsp;Aryan Esfandiari MSc,&nbsp;Jorge Cardoso PhD,&nbsp;Parashkev Nachev PhD","doi":"10.1016/j.arrct.2026.100673","DOIUrl":"10.1016/j.arrct.2026.100673","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the feasibility of automated action recognition and movement characterization during the Performance-Oriented Mobility Assessment (POMA) using markerless three-dimensional pose estimation and to explore whether data-driven whole-body movement analysis differentiates healthy adults from stroke survivors.</div></div><div><h3>Design</h3><div>Observational, cross-sectional proof-of-concept study</div></div><div><h3>Setting</h3><div>Single-center study conducted at a UK National Health Service Hospital stroke unit.</div></div><div><h3>Participants</h3><div>Fifty-six healthy adults and 17 stroke survivors able to complete the POMA assessment (N=73).</div></div><div><h3>Intervention</h3><div>Participants completed the POMA under therapist supervision while recorded using 2 synchronized RGB cameras. Major joints were extracted to generate skeletal representations, which were analyzed using machine-learning methods to automatically detect distinct POMA actions.</div></div><div><h3>Main Outcome Measures</h3><div>Primary outcomes were overall action recognition accuracy and F1 scores for individual POMA actions. Secondary outcomes included qualitative and quantitative differences in movement patterns between healthy participants and participants with stroke derived from whole-body kinematic embeddings.</div></div><div><h3>Results</h3><div>The action recognition model achieved a mean classification accuracy of 78.9%. Performance was highest for sitting, standing, and turning, with F1 scores of 0.95, 0.82, and 0.80, respectively. Low-dimensional embeddings of movement trajectories revealed distinct clustering patterns and greater dispersion among participants stroke, consistent with impaired balance and gait control.</div></div><div><h3>Conclusions</h3><div>Markerless pose estimation combined with machine-learning analysis can accurately recognize actions and detect clinically meaningful differences in movement during a standardized balance and gait assessment. Although exploratory, these findings illustrate the potential of artificial intelligence to characterize movement patterns and identify kinematic features distinguishing patient groups. This approach offers a pathway toward scalable, objective, and automated motor assessment, with the potential to identify patients at risk of functional decline and support targeted clinical interventions.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100673"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Central Neuropathic Pain Following Stroke Presenting With Distal Movement-Evoked Shoulder Pain: A Case Report","authors":"Joon Sin Ser MBBS, MRCP,&nbsp;Sangita Kuparasundram MBBS, MMed, MRCP, GDFM, FAMS","doi":"10.1016/j.arrct.2026.100637","DOIUrl":"10.1016/j.arrct.2026.100637","url":null,"abstract":"<div><div>This case report describes a unique presentation of central neuropathic pain (CNP) in a Chinese male in his 40s, following a large right basal ganglia hemorrhage with extension into the right middle cerebral artery (MCA) territory, characterized by left shoulder pain reproducibly triggered by passive wrist and finger extension. The report outlines the sequential treatment approach implemented for pain management. Although spasticity and shoulder pain are common sequelae of stroke, this case highlights the importance of considering central neuropathic mechanisms in patients with atypical or refractory symptoms. It also underscores the heterogeneity of CNP following stroke and the need for heightened clinical awareness of this condition.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100637"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjustable Pediatric Prosthetic Sockets to Accommodate Growth in Children and Adolescents With Limb Loss","authors":"Timothy R. Dillingham MS, MD,&nbsp;Jessica Kenia MS,&nbsp;Laura Prosser PT, PhD,&nbsp;James Marschalek MS,&nbsp;Frances Shofer PhD,&nbsp;Liliana E. Pezzin PhD","doi":"10.1016/j.arrct.2026.100670","DOIUrl":"10.1016/j.arrct.2026.100670","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the feasibility, comfort, user satisfaction, and functional performance of an adjustable, immediate-fit prosthetic socket in children and adolescents with lower-limb loss.</div></div><div><h3>Design</h3><div>Prospective clinical trial.</div></div><div><h3>Setting</h3><div>Gait and biomechanics lab in an outpatient rehabilitation hospital.</div></div><div><h3>Participants</h3><div>Twenty-eight pediatric participants (14 boys, 14 girls; average age 11.5±4.0y) were enrolled; 26 were eligible for the home trial.</div></div><div><h3>Intervention</h3><div>Each participant was fit with an adjustable, immediate-fit prosthesis, which was compared with the users’ conventional devices.</div></div><div><h3>Main Outcome Measures</h3><div>Prosthetic Evaluation Questionnaire (PEQ) scores (use and satisfaction) with additional items on comfort; temporal gait parameters (gait speed, single-limb support); intrasocket pressure measurements; and adverse events (falls, skin irritation, device issues).</div></div><div><h3>Results</h3><div>Fifteen participants completed follow-up. Overall PEQ scores favored the adjustable device, although not significantly (45.8 vs 42.5, <em>P</em>=.29). Ease of socket adjustment demonstrated a significant advantage for the adjustable prosthesis (mean difference=1.53, <em>P</em>=.0019). Participants also reported improved temperature and perspiration control (mean difference=1.07, <em>P</em>=.0007). Walking speed did not differ between devices (<em>P</em>=.24), and intrasocket pressures were comparable (<em>P</em>=.74). No skin irritation, skin breakdown, or mechanical failures were observed or reported.</div></div><div><h3>Conclusions</h3><div>The adjustable, immediate-fit pediatric prosthetic system was feasible and well accepted. It performed comparably with conventional devices on gait and pressure metrics and demonstrated ease of use and improvements in factors associated with skin integrity. These findings suggest that adjustable sockets may offer a practical, affordable alternative for children and families seeking a device that can accommodate growth.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100670"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Telerehabilitation on Functional and Other Health-Related Outcomes in Colorectal Cancer Patients and Survivors: A Systematic Review and Meta-analysis","authors":"Yee Hong Low MMED,&nbsp;Fuquan Zhang MD,&nbsp;San San Tay MMED","doi":"10.1016/j.arrct.2026.100631","DOIUrl":"10.1016/j.arrct.2026.100631","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review and meta-analysis evaluated the effects of telerehabilitation interventions on functional and health-related outcomes, and physical activity levels in individuals diagnosed with colorectal cancer (CRC).</div></div><div><h3>Data Sources</h3><div>A systematic literature search encompassing PubMed, Embase, and CINAHL electronic databases was performed from inception to September 11, 2024.</div></div><div><h3>Study Selection</h3><div>The inclusion criteria included randomized controlled trials exploring the effect of telerehabilitation on improving functional and health-related outcomes in patients with CRC and survivors.</div></div><div><h3>Data Extraction</h3><div>Two independent reviewers conducted the data extraction. The methodological quality of included studies was evaluated using the Cochrane Risk of Bias Tool 2.0 (RoB 2). A quantitative synthesis, employing meta-analysis, was conducted utilizing Cochrane Review Manager software (RevMan 5.4).</div></div><div><h3>Data Synthesis</h3><div>Eleven randomized control trials with a total of 844 participants were included in this analysis. Variation in intervention designs precludes the identification of the most effective telerehabilitation program. Telerehabilitation improved quality of life more than control (standard mean difference=0.33; 95% CI, 0.01-0.64; <em>P</em>=.04; I²=14%). However, there was no significant difference in physical function, physical activity, fatigue, and depression between the telerehabilitation group and the control group.</div></div><div><h3>Conclusions</h3><div>Telerehabilitation significantly enhances the quality of life in CRC survivors. However, its impact on physical function is obscured by heterogeneity in intervention designs, inconsistent outcome measures, and potential study biases. Future research should implement robust blinding procedures while prioritizing individualized exercise prescriptions and objective outcome measures.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 3","pages":"Article 100631"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}