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Relação entre a infecção por Helicobacter pylori e doenças metabólicas: uma revisão integrativa 幽门螺杆菌感染与代谢疾病的关系:一项综合综述
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.22491/2357-9730.125129
Felipe Augusto de Sousa Moraes, Gabriel Ribeiro Maximo, Giovana Alice Sampaio Soares, Mônica Santiago Barbosa
{"title":"Relação entre a infecção por Helicobacter pylori e doenças metabólicas: uma revisão integrativa","authors":"Felipe Augusto de Sousa Moraes, Gabriel Ribeiro Maximo, Giovana Alice Sampaio Soares, Mônica Santiago Barbosa","doi":"10.22491/2357-9730.125129","DOIUrl":"https://doi.org/10.22491/2357-9730.125129","url":null,"abstract":"Helicobacter pylori é uma bactéria Gram-negativa que acomete cerca de 50% da população mundial. A infecção causada por H. pyloriestá associada com algumas enfermidades gástricas. Entretanto, estudos mais recentes têm demonstrado a etiologia do microrganismo em doenças extra gástricas, como doenças metabólicas. O trabalho teve como objetivo realizar uma pesquisa na literatura de artigos que avaliaram a associação da infecção por H. pyloricom doenças metabólicas, com foco em diabetes. Foram utilizadas as seguintes bases de dados, PubMed, Medline, LILACS e SciELO. Termos combinados juntamente com o operador booleano “AND” em português e em inglês foram empregados. O resultado do levantamento bibliográfico totalizou 31 artigos. A infecção por H. pyloripossivelmente está relacionada com a síndrome metabólica. A relação pode ser decorrente da inflamação crônica, redução dos movimentos gastrointestinais, falta de secreção de ácido gástrico e interferência na produção ou secreção de alguns hormônios. Apesar dos estudos demonstrarem que entre os indivíduos infectados por H.pyloria prevalência da síndrome metabólica é maior e que a erradicação do microrganismo favorece a melhora dos índices glicêmicos, mais pesquisas são requeridas. A compreensão da etiologia da infecção porH. pyloriem doenças metabólicas, pode auxiliar em políticas públicas de erradicação da bactéria.","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135843297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aorto-enteric fistula: a case report 主动脉-肠瘘1例
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.22491/2357-9730.125213
Ricardo Henrique Bilycz Corrêa, Mateus Torres Avelar de Lima, Eduardo Neumann Tavares, Franco Andreas Scola, Mariana Mendes Knabben
{"title":"Aorto-enteric fistula: a case report","authors":"Ricardo Henrique Bilycz Corrêa, Mateus Torres Avelar de Lima, Eduardo Neumann Tavares, Franco Andreas Scola, Mariana Mendes Knabben","doi":"10.22491/2357-9730.125213","DOIUrl":"https://doi.org/10.22491/2357-9730.125213","url":null,"abstract":"A case report focused on imaging aspects of an aorto-enteric fistula (AEF) in a 39-year-old patient with a recent diagnosis of classic Hodgkin Lymphoma with multiple enlarged retroperitoneal lymph nodes. AEF is a pathologic communication between the aortic lumen and any portion of the gastrointestinal tract. Without prompt intervention, the associated mortality approaches 100%. Early clinical suspicion is essential for a successful outcome and the role of imaging is fundamental to diagnose it. Owing to its widespread availability, short acquisition time, and high resolution, CT with intravenous contrast has become the first-line modality for imaging evaluation of suspected aorto-enteric fistula.","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135844617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Covid-19: Como informações baseadas em evidências auxiliaram um hospital terciário durante o primeiro ano pandêmico Covid-19:基于证据的信息如何在大流行的第一年帮助一家三级医院
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.22491/2357-9730.125970
Tázia Lopes de Castro, Andrea Cássia Pereira Sforsin, Vanusa Barbosa Pinto, Tiago Arantes, Maria Alice Pimentel Falcão
{"title":"Covid-19: Como informações baseadas em evidências auxiliaram um hospital terciário durante o primeiro ano pandêmico","authors":"Tázia Lopes de Castro, Andrea Cássia Pereira Sforsin, Vanusa Barbosa Pinto, Tiago Arantes, Maria Alice Pimentel Falcão","doi":"10.22491/2357-9730.125970","DOIUrl":"https://doi.org/10.22491/2357-9730.125970","url":null,"abstract":"Durante a pandemia de COVID-19, a necessidade por uma informação confiável, rápida e precisa desafiou os profissionais de saúde de todo o mundo. O objetivo deste trabalho foi avaliar e comparar as solicitações dos profissionais da saúde realizadas a um Centro de Informação Sobre Medicamentos (CIM) em um ano pré-pandêmico e durante o primeiro ano pandêmico.","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135844844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Ultrasound Liver Attenuation Imaging for Detection of Liver Steatosis: Comparison with MRI Based Imaging Methods with Liver Biopsy as A Reference Standard 新型超声肝衰减成像检测肝脂肪变性:与以肝活检为参考标准的MRI成像方法的比较
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.26502/acbr.50170368
Chileka Chiyanika, Kin Hung Liu, Vincent Wai-Sun Wong, Winnie Chiu Wing Chu
{"title":"Novel Ultrasound Liver Attenuation Imaging for Detection of Liver Steatosis: Comparison with MRI Based Imaging Methods with Liver Biopsy as A Reference Standard","authors":"Chileka Chiyanika, Kin Hung Liu, Vincent Wai-Sun Wong, Winnie Chiu Wing Chu","doi":"10.26502/acbr.50170368","DOIUrl":"https://doi.org/10.26502/acbr.50170368","url":null,"abstract":"Background and aim: Non-alcoholic fatty liver disease is a predominant cause of chronic liver disease worldwide. The aim of this study was to evaluate the performance of the novel ultrasound attenuation imaging (ATI) with MRI-proton density fat fraction (PDFF) and proton magnetic resonance spectroscopy (proton-MRS) in detecting and grading of liver steatosis, using liver biopsy as a reference standard.","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135959787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Real-time Squiggle Classification for Read until using RawMap. 使用RawMap之前读取的快速实时波形分类。
Archives of clinical and biomedical research Pub Date : 2023-01-01 Epub Date: 2023-01-28 DOI: 10.26502/acbr.50170318
Harisankar Sadasivan, Jack Wadden, Kush Goliya, Piyush Ranjan, Robert P Dickson, David Blaauw, Reetuparna Das, Satish Narayanasamy
{"title":"Rapid Real-time Squiggle Classification for Read until using RawMap.","authors":"Harisankar Sadasivan, Jack Wadden, Kush Goliya, Piyush Ranjan, Robert P Dickson, David Blaauw, Reetuparna Das, Satish Narayanasamy","doi":"10.26502/acbr.50170318","DOIUrl":"10.26502/acbr.50170318","url":null,"abstract":"<p><p>ReadUntil enables Oxford Nanopore Technology's (ONT) sequencers to selectively sequence reads of target species in real-time. This enables efficient microbial enrichment for applications such as microbial abundance estimation and is particularly beneficial for metagenomic samples with a very high fraction of non-target reads (> 99% can be human reads). However, read-until requires a fast and accurate software filter that analyzes a short prefix of a read and determines if it belongs to a microbe of interest (target) or not. The baseline Read Until pipeline uses a deep neural network-based basecaller called Guppy and is slow and inaccurate for this task (~60% of bases sequenced are unclassified). We present RawMap, an efficient CPU-only microbial species-agnostic Read Until classifier for filtering non-target human reads in the squiggle space. RawMap uses a Support Vector Machine (SVM), which is trained to distinguish human from microbe using non-linear and non-stationary characteristics of ONT's squiggle output (continuous electrical signals). Compared to the baseline Read Until pipeline, RawMap is a 1327X faster classifier and significantly improves the sequencing time and cost, and compute time savings. We show that RawMap augmented pipelines reduce sequencing time and cost by ~24% and computing cost by 22%. Additionally, since RawMap is agnostic to microbial species, it can also classify microbial species it is not trained on. We also discuss how RawMap may be used as an alternative to the RT-PCR test for viral load quantification of SARS-CoV-2.</p>","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"7 1","pages":"45-57"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022530/pdf/nihms-1875752.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9705992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparative Study of Inflammatory Markers in Diabetics versus Non- Diabetics with Covid-19 and their Impact on Morbidity and Mortality Outcomes 糖尿病与非糖尿病合并Covid-19患者炎症标志物的比较研究及其对发病率和死亡率结果的影响
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.26502/acbr.50170364
Vathul B Subramanian, B. H, P. Kulkarni
{"title":"A Comparative Study of Inflammatory Markers in Diabetics versus Non- Diabetics with Covid-19 and their Impact on Morbidity and Mortality Outcomes","authors":"Vathul B Subramanian, B. H, P. Kulkarni","doi":"10.26502/acbr.50170364","DOIUrl":"https://doi.org/10.26502/acbr.50170364","url":null,"abstract":"","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69341545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hard to Swallow: Remembering to Check for Impacted Dentures in Elderly Patients Presenting with Swallowing Difficulty 吞咽困难:在出现吞咽困难的老年患者中记得检查假牙
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.26502/acbr.50170328
Priyavarshini Ramesh, Cerys Morgan, M. Fertleman, Louis John Koizia
{"title":"Hard to Swallow: Remembering to Check for Impacted Dentures in Elderly Patients Presenting with Swallowing Difficulty","authors":"Priyavarshini Ramesh, Cerys Morgan, M. Fertleman, Louis John Koizia","doi":"10.26502/acbr.50170328","DOIUrl":"https://doi.org/10.26502/acbr.50170328","url":null,"abstract":"","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69341699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug-drug interactions of immunosuppressants and other drugs in kidney post-transplant recipients 肾移植后受者免疫抑制剂和其他药物的药物相互作用
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.22491/2357-9730.128108
Mariel Umana-Rivas, Evelin Soares de Brito, Letícia Santana da Silva Soares, Geraldo Rubens Ramos de Freitas, Gustavo Queiroz Arimatea, Priscila Dias Gonçalves, Dayani Galato
{"title":"Drug-drug interactions of immunosuppressants and other drugs in kidney post-transplant recipients","authors":"Mariel Umana-Rivas, Evelin Soares de Brito, Letícia Santana da Silva Soares, Geraldo Rubens Ramos de Freitas, Gustavo Queiroz Arimatea, Priscila Dias Gonçalves, Dayani Galato","doi":"10.22491/2357-9730.128108","DOIUrl":"https://doi.org/10.22491/2357-9730.128108","url":null,"abstract":"Immunosuppressants (ISS) are the most crucial tools used in the therapeutic regimens of transplant recipients. Nevertheless, these drugs are not the only ones adopted by patients; therefore, knowing the possible drug-drug interactions (DDIs) between immunosuppressants and other drugs commonly used in kidney transplant recipients is essential to ensure the effectiveness and safety of treatments. In this way, the objective is analyzing the DDIs between the immunosuppressants and other commonly used medications on kidney transplant adult recipients with active medical records undergoing post-transplant follow-up for 4.4 years (mean).","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Análise das solicitações de medicamentos não padronizados de um hospital universitário terciário 某大专医院非标药品需求分析
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.22491/2357-9730.129285
Tiago Arantes, Dayane Santos, Leonardo Jun Otuyama, Andrea Cassia Pereira Sforsin, Maria Alice Pimentel Falcão, Fabíola Amargos Defácio, Vanusa Barbosa Pinto
{"title":"Análise das solicitações de medicamentos não padronizados de um hospital universitário terciário","authors":"Tiago Arantes, Dayane Santos, Leonardo Jun Otuyama, Andrea Cassia Pereira Sforsin, Maria Alice Pimentel Falcão, Fabíola Amargos Defácio, Vanusa Barbosa Pinto","doi":"10.22491/2357-9730.129285","DOIUrl":"https://doi.org/10.22491/2357-9730.129285","url":null,"abstract":"O uso extensivo de medicamentos não padronizados causa aumento de custos em saúde, além de potencial redução de segurança e uso racional de medicamentos. A Comissão de Farmácia e Terapêutica orienta a prescrição de medicamentos, por meio da avaliação e seleção de medicamentos a serem incluídos no formulário de medicamentos padronizados, com base nas melhores evidências científicas disponíveis e no perfil dos pacientes locais, promovendo o uso racional de medicamentos. O objetivo deste trabalho foi analisar as solicitações de fornecimento de medicamentos não padronizados na instituição.","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135843665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pneumonia eosinofílica e provável Síndrome de Churg-Strauss: um relato de caso 嗜酸性肺炎和可能的丘格-施特劳斯综合征:一个病例报告
Archives of clinical and biomedical research Pub Date : 2023-01-01 DOI: 10.22491/2357-9730.126327
Alícia Regina Zambiasi, Ana Katharina Dalbosco, Giordana Vitória Bertozzo Suzin, Lucas Zambiasi
{"title":"Pneumonia eosinofílica e provável Síndrome de Churg-Strauss: um relato de caso","authors":"Alícia Regina Zambiasi, Ana Katharina Dalbosco, Giordana Vitória Bertozzo Suzin, Lucas Zambiasi","doi":"10.22491/2357-9730.126327","DOIUrl":"https://doi.org/10.22491/2357-9730.126327","url":null,"abstract":"As doenças pulmonares eosinofílicas compõe um grupo heterogêneo de patologias que possuem uma característica em comum: elevado número de eosinófilos nas vias aéreas e no parênquima pulmonar. Uma das formas de eosinofilia pulmonar é a Síndrome de Churg-Strauss (SCS), que é uma doença multissistêmica a qual possui evolução subaguda com três fases clínicas sequenciais: a prodrômica, a eosinofílica e a vasculítica. A hipótese diagnóstica pode ser considerada quando um padrão de opacidades em vidro fosco e consolidações são vistos em paciente com história de asma com eosinofilia.","PeriodicalId":72279,"journal":{"name":"Archives of clinical and biomedical research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135844874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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