Detection of Her 2/Neu Equivocal Immunochemistry by Fish in Breast Carcinoma – A Study from Single Tertiary Care Hospital

Abstract

Background: Both IHC and FISH were used for Human epidermal growth factor receptor-2 status testing but for confirmation of all equivocal specimens having +2 score (Her-2 status) in IHC, the FISH method is used. We report a prospective study to reflect the concordance between IHC and FISH in Her-2 status confirmation.