Alexis Redding, Harideep Samanapally, Mike O Udoh, Jiapeng Huang, Mark S Slaughter, Siddharth Pahwa
{"title":"Coronary Artery Bypass Grafting complicated by post-operative coronavirus infection - two similar presentations with dissimilar outcomes.","authors":"Alexis Redding, Harideep Samanapally, Mike O Udoh, Jiapeng Huang, Mark S Slaughter, Siddharth Pahwa","doi":"10.22551/2023.38.1001.10230","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10230","url":null,"abstract":"<p><p>Patients diagnosed with COVID-19 infection undergoing surgical procedures have been reported to have increased post-operative complications and mortality. These findings are important when considering cardiac surgical procedures, specifically coronary artery bypass grafting (CABG) during this pandemic, since the Society of Thoracic Surgeons (STS) describes most of these operations as 'urgent'. In addition, the majority of cardiac surgical patients are at increased risk of infection and death with COVID-19, as they are frequently of old age, obese, hypertensive, and diabetic, with severe cardiac or pulmonary diseases. This case series describes the clinical course following a CABG procedure in two patients that went on to develop COVID-19 infection post-operatively. We aim to illustrate the similarities in clinical presentation, but differences in eventual outcomes for both patients and hypothesize the reasons for the differences.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/11/acc-10-01-7.PMC9940284.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9341779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camille Garcia, Giulia Fusi, Marion Gambart, Agnès Sartor, Anne Gomez-Mascard, Olivier Abbo
{"title":"Prenatal diagnosis of an adrenal mature teratoma mimicking a neuroblastoma.","authors":"Camille Garcia, Giulia Fusi, Marion Gambart, Agnès Sartor, Anne Gomez-Mascard, Olivier Abbo","doi":"10.22551/2023.39.1002.10243","DOIUrl":"https://doi.org/10.22551/2023.39.1002.10243","url":null,"abstract":"<p><p>Teratomas are defined by the presence of cell types from different germ layers, they typically involve the gonads or the sacrococcygeal region and are rarely retroperitoneal. Prenatally detected adrenal teratomas are extremely uncommon. Aim of this paper is to share our experience with an adrenal antenatal mass initially diagnosed as a left adrenal neuroblastoma that turned out to be a mature teratoma after microscopical examination. We present the case of a male fetus with antenatal diagnosis of a left adrenal cystic image at the 22nd week of amenorrhea. The fetal magnetic resonance imaging showed a non-calcified cystic mass of the left adrenal gland, compatible with a neuroblastoma. At birth an ultrasound confirmed the presence of an anechogenic lesion of the left adrenal gland. The infant was closely monitored during his first year and in the absence of significant regression of the adrenal mass, it was decided to perform a laparoscopic left adrenalectomy. Unexpectedly, the final pathological diagnosis was mature cystic adrenal teratoma. In conclusion, an adrenal mass diagnosed antenatally is generally a hemorrhage or a neuroblastoma. Adrenal teratomas are very rare and those diagnosed antenatally even more. At present, we have no clinical, biological, or radiological evidence to suspect them before surgical removal. There are only two other cases of unexpected adrenal teratoma in infants described in Literature.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 2","pages":"66-69"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/19/acc-10-10243.PMC10201373.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9510044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yousef A I Abousedu, Athary Saleem, Saqer Alenezi, Petar Bosnjakovic, Lazar Lazovic, Tarik M Alsheikh
{"title":"Spontaneous thrombosis of a giant cavernous-carotid aneurysm with simultaneous ipsilateral complete parent artery occlusion: a rare phenomenon and review of the literature.","authors":"Yousef A I Abousedu, Athary Saleem, Saqer Alenezi, Petar Bosnjakovic, Lazar Lazovic, Tarik M Alsheikh","doi":"10.22551/2023.38.1001.10234","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10234","url":null,"abstract":"<p><p>Cavernous-carotid artery (CCA) aneurysms represent about 3-5% of all intracranial aneurysms. Spontaneous thrombosis of a CCA aneurysm with simultaneous occlusion of its parent vessel is an extremely rare phenomenon with few reported cases in the literature offering different management strategies. A 54-year-old Asian female presented with a one day-history of painless left eye conjunctival injection, proptosis, and features of cavernous sinus syndrome (cranial nerve III, IV, V1, V2, and VI palsies). Imaging revealed a giant thrombosed CCA aneurysm measuring 3.6cmx3.4cm with complete thrombosis of the left cervical internal carotid artery (ICA) and adequate collaterals from the anterior and posterior communicating artery and branches of the left external carotid artery. Management was conservative with antiplatelet therapy and close clinical-radiological follow-ups. The outcome was satisfactory. Data in the literature on this condition is limited due to its exceedingly rare occurrence. The majority of patients do well via a conservative approach and surgery is rarely indicated. For clinically stable patients, especially those with adequate collateral circulation and tolerance to Balloon Test Occlusion, we advocate for a conservative approach and initiation of anti-platelet therapy to treat these patients. Emphasis is needed on close serial clinical-radiological surveillance in these cases to monitor the propagation of the thrombus as well as the development of new and/or enlarging pre-existing aneurysms in the contralateral ICA circulation.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"21-28"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/91/89/acc-10-01-21.PMC9940282.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9288673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristina Marques, Catarina Silva, Carina Silva, João Pedro Abreu, Márcia Ribeiro, Arlindo Guimas
{"title":"From recurrent rhabdomyolysis in a young adult to carnitine palmitoyltransferase II deficiency.","authors":"Cristina Marques, Catarina Silva, Carina Silva, João Pedro Abreu, Márcia Ribeiro, Arlindo Guimas","doi":"10.22551/2023.38.1001.10238","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10238","url":null,"abstract":"<p><p>Metabolic myopathies are a diverse group of rare genetic disorders associated with recurrent episodes of rhabdomyolysis, induced by triggers such as fever or exercise. In these disorders, the energetic metabolism is compromised resulting in damage of the muscle cells. The diagnosis can be challenging but is essential for the correct treatment. Carnitine palmitoytransferase II (CPT-II) deficiency is the most common long-chain fatty acid oxidation defect, with the adulthood form requiring additional external triggers. The authors present a case of a young-male adult with recurrent episodes of rhabdomyolysis, one of them presented with acute renal failure and acute hepatitis. The diagnostic is demanding, which requires a high level of suspicion. The adequate treatment of these patients improves the muscle function and prevents other episodes of severe rhabdomyolysis.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"42-46"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/55/acc-10-01-42.PMC10088049.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9305490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute meningitis complicated with ventriculitis caused by <i>Streptococcus dysgalactiae subsp. dysgalactiae</i>.","authors":"Mariana Guerra, Daniela Marado, Jorge Fortuna","doi":"10.22551/2023.38.1001.10231","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10231","url":null,"abstract":"<p><p><i>Streptococcus dysgalactiae subspecies dysgalactiae</i> (SDSD), also known as Lancefield group C streptococcus, is a pathogen found in animals. It is known to cause pyogenic infections in animals and is one of the most common pathogens that can cause mastitis in cattle. Very few reports of SDSD causing human diseases to have been reported in the literature, but we report a case of community-acquired meningitis and pyogenic ventriculitis caused by SDSD. This report is the first case of SDSD causing a central nervous system (CNS) infection in humans and aims to raise awareness about the role of SDSD in CNS infections. It also seeks to promote the recognition of this bacteria as a potential cause of invasive diseases.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"11-14"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/9f/acc-10-01-11.PMC9940286.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10823554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare case of mobile diplopodia mistaken for polydactyly.","authors":"Timothy Woodacre, Sarah Dunkerley, Peter J Cox","doi":"10.22551/2023.38.1001.10232","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10232","url":null,"abstract":"<p><p>We present a rare case of a mobile diplopodia in an infant with disorganization syndrome. This was initially mistaken for polydactyly due to the more typical association between these conditions. The resulting corrective surgery was more extensive and complicated than anticipated, with the removal of a partial foot duplication and reconstruction of residual hindfoot structures, rather than the planned digit amputation. We highlight the association of diplopodia with disorganization syndrome, discuss differentiating diplopodia from polydactyly and describe the surgical management of an unusual case.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"15-17"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/be/acc-10-01-15.PMC9940283.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10823555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoph Sucker, Christof Geisen, Jens Litmathe, Ursula Schmitt
{"title":"Concomitant hypofibrinogenemia and factor XI deficiency as rare cause of bleeding during urgent dentistry: case report and short review of the literature.","authors":"Christoph Sucker, Christof Geisen, Jens Litmathe, Ursula Schmitt","doi":"10.22551/2023.39.1002.10253","DOIUrl":"https://doi.org/10.22551/2023.39.1002.10253","url":null,"abstract":"<p><p>Hypofibrinogenemia and Factor XI deficiency are rare defects of hemostasis, potentially leading to spontaneous bleeding manifestations and increased bleeding risk during surgery, dentistry, and interventions. Due to the different mode of inheritance, the concomitance of both defects is extremely rare and the clinical management of combined hypofibrinogenemia and factor XI deficiency is not standardized. Here, we report a rare case of concomitant genetically determined hypofibrinogenemia and factor XI deficiency as a cause of increased spontaneous bleeding and bleeding complications during dentistry. The diagnostic procedure including screening assays, single clotting factor determinations, genetic analyses, and also use of thrombin generation assays (TGA) are described. Also, we present our considerations regarding the development of an adequate prophylaxis of bleeding with fibrinogen concentrate in this case. The literature regarding the issue is briefly discussed.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 2","pages":"110-113"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/78/acc-10-10253.PMC10315684.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9793287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"'Patience is a virtue' - Post-traumatic Axillary Web Syndrome - resolution without intervention.","authors":"Jaleel Mohammed, Catherine Ash, Jayanti Rai","doi":"10.22551/2023.38.1001.10233","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10233","url":null,"abstract":"<p><p>The current case report showcases an atypical symptomatic post-traumatic Axillary Web Syndrome in a 63-year-old Caucasian male patient with complete resolution of symptoms with no intervention. Axillary web syndrome is a condition where the skin area under the axilla becomes taut and on palpation there is a cord-like feeling similar to a guitar string, usually bound together as spider web appearance. The case report highlights the importance of appropriate physical examination and also the need for Community Diagnostic Centres and Point of Care Ultrasound services to help provide patients with timely diagnosis, reduce patient anxiety, and enhance patient experience and outcomes. The current case study is specifically useful for healthcare professionals working in primary care, especially in the National Health Service, where resources are already stretched to avoid unnecessary referrals, interventions and investigations. The case report is atypical since axillary web syndrome is typically and largely seen in cancer patients, specifically post breast cancer surgery in females and very rarely seen as a post traumatic presentation in acute setting.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"18-20"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/19/acc-10-01-18.PMC9940285.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10823557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Mangini, Elvira Bruno, Remo Caramia, Roberto Flora, Eluisa Muscogiuri, Antonio Medico, Grazia Casavecchia, Robert W W Biederman, Rinaldo Giaccari
{"title":"Effectiveness of levosimendan and role of cardiac magnetic resonance in cardiogenic shock due to COVID-19 related lymphocytic myocarditis in the course of viral sepsis.","authors":"Francesco Mangini, Elvira Bruno, Remo Caramia, Roberto Flora, Eluisa Muscogiuri, Antonio Medico, Grazia Casavecchia, Robert W W Biederman, Rinaldo Giaccari","doi":"10.22551/2023.38.1001.10236","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10236","url":null,"abstract":"<p><p>COVID-19 and sepsis pose great challenges to clinicians and growing evidence is demonstrating links between the two conditions. Both can be complicated by acute heart failure. The use of levosimendan in patients with ventricular dysfunction during COVID-19 infection and sepsis has very little evidence. A 46-year-old, hypertensive and obese patient was admitted for severe left ventricular failure and shock during sepsis following a COVID-19 infection. The patient was treated first with norepinephrine, which was partially effective, then with the addition of levosimendan as a continuous 24 hours infusion. Vital signs and echocardiographic systolic performance indices, such as FE, SVi, CI, dP/dT, TAPSE, and tricuspid S-wave velocity, as well as diastolic function, were recorded at access, 12 and 24 hours. After initiation of levosimendan, a rapid improvement in vital signs and systolic and diastolic performance indices was observed, not depending on changes in preload, afterload, and inflammatory status. Blood cultures were negative for the presence of bacteria, thus defining the picture of likely viral sepsis. Cardiac magnetic resonance was determinant, showing a picture of myocarditis sustained by immune processes rather than direct viral injury, which was confirmed by endomyocardial biopsy. In conclusion, this case highlights the efficacy of levosimendan in acute heart failure complicated by shock due to COVID-19-related myocarditis and concomitant sepsis and confirms cardiac magnetic resonance as the gold standard for the diagnosis of myocardial inflammatory disease. To the best of our knowledge, this is the first documented case of effective use of levosimendan in this context.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"32-38"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b1/a3/acc-10-01-32.PMC10012167.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9133108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
João Campos Cunha, António José Cruz, Beatriz Madureira, Yolanda Martins, Gonçalo Sarmento
{"title":"Acute Aortic Syndrome in a patient with COVID-19.","authors":"João Campos Cunha, António José Cruz, Beatriz Madureira, Yolanda Martins, Gonçalo Sarmento","doi":"10.22551/2023.38.1001.10239","DOIUrl":"https://doi.org/10.22551/2023.38.1001.10239","url":null,"abstract":"<p><p>The global effects of the COVID-19 pandemic make it of the utmost importance to comprehend its mechanisms and define strategies for the most effective approach possible. The SARS-CoV-2 virus can be responsible for the induction of a hypercoagulable state, which can trigger vascular phenomena of venous etiology, specifically deep venous thrombosis or pulmonary embolism. Arterial thrombotic events associated with COVID-19 have also been described in the medical literature, although less frequently. In this paper the authors report the case of a 66-year-old man who was diagnosed with an Acute Aortic Syndrome, specifically an intramural thrombus on the aortic arch, while he was still infected with the virus. Anticoagulation with low weight molecular heparin was initiated and the patient was admitted at the Internal Medicine ward for a conservative therapeutic approach. The thrombus remained stable on a serial imaging evaluation; therefore, the patient was discharged with oral anticoagulation with subsequent follow-up in the outpatient clinic. This case describes a rare and potentially serious complication of COVID-19, which highlights how broad its clinical spectrum can be, affecting systems other than the pulmonary.</p>","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 1","pages":"47-49"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f9/f7/acc-10-01-47.PMC10088050.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9305488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}