Advanced Biomedical Research最新文献_第8页

Human Respiratory Syncytial Virus and Coronavirus Rates in Iranian Elderly Patients More than 60 Years Old with Acute Respiratory Symptoms. 伊朗60岁以上急性呼吸道症状老年人呼吸道合胞体病毒和冠状病毒感染率

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_395_22

Shaian Tavakolian, Hossein Goudarzi, Ilad Alavi Darazam, Ebrahim Faghihloo

{"title":"Human Respiratory Syncytial Virus and Coronavirus Rates in Iranian Elderly Patients More than 60 Years Old with Acute Respiratory Symptoms.","authors":"Shaian Tavakolian, Hossein Goudarzi, Ilad Alavi Darazam, Ebrahim Faghihloo","doi":"10.4103/abr.abr_395_22","DOIUrl":"https://doi.org/10.4103/abr.abr_395_22","url":null,"abstract":"Background: Scientists have believed that a number of risk factors, especially viral infectious agents, can be related to respiratory diseases. Due to the pandemics in 2019, Human Respiratory Syncytial Virus and Coronavirus have attracted the attention of different kinds of research. In this study, we attempted to evaluate the prevalence of these viruses.Materials and methods: After extracting the RNA and DNA of these viruses, molecular tests were employed to report the rate of them in patients suffering from respiratory symptoms.Results: Our results demonstrated that 31 samples were COVID-19 positive. Furthermore, two cases had Respiratory syncytial virus (RSV) subgroup A infections. However, no cases showed a coinfection of both viruses.Conclusions: It seems that during the pandemic of COVID-19, RSV should not be ignored as it can be responsible for the respiratory syndrome.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"180"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/fc/ABR-12-180.PMC10492601.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10222223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Status of Hypertension Control in Urban Slums of Central India: A community Health Worker-Based Two-Year Follow-Up. 印度中部城市贫民窟高血压控制状况:以社区卫生工作者为基础的两年随访。

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_266_22

Abhijit Pakhare, Anuja Lahiri, Neelesh Shrivastava, Krishna N Subba, Vaishnavi Veera Durga Kurra, Ankur Joshi, Shubham Atal, Sagar Khadanga, Rajnish Joshi

{"title":"Status of Hypertension Control in Urban Slums of Central India: A community Health Worker-Based Two-Year Follow-Up.","authors":"Abhijit Pakhare, Anuja Lahiri, Neelesh Shrivastava, Krishna N Subba, Vaishnavi Veera Durga Kurra, Ankur Joshi, Shubham Atal, Sagar Khadanga, Rajnish Joshi","doi":"10.4103/abr.abr_266_22","DOIUrl":"https://doi.org/10.4103/abr.abr_266_22","url":null,"abstract":"Background: Hypertension (HTN) is a leading cause of cardiovascular diseases and its control is poor. There is heterogeneity in levels of blood pressure control among various population subgroups. The present study was conducted within the framework of the National Program for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases, and Stroke (NPCDCS) in India. It aims to estimate the proportion of optimal blood pressure control and identify factors associated with uncontrolled HTN consequent to initial screening.Materials and methods: We assembled a cohort of individuals with HTN confirmed in a baseline screening in sixteen urban slum clusters of Bhopal (2017-2018). Sixteen accredited social health activists were trained from within these slums. Individuals with HTN were linked to primary care providers and followed up for the next two years. Obtaining optimal blood pressure control (defined as SBP <140 and DBP <90 mm of Hg) was a key outcome.Results: Of a total of 6174 individuals, 1571 (25.4%) had HTN, of which 813 were previously known and 758 were newly detected during the baseline survey. Two-year follow-up was completed for 1177 (74.9%). Blood pressure was optimally controlled in 301 (26%) at baseline and in 442 (38%) individuals at two years (an absolute increase of 12%; 95% CI 10.2-13.9). Older age, physical inactivity, higher body mass index, and newly diagnosed HTN were significantly associated with uncontrolled blood pressure.Conclusion: We found about six of every ten individuals with HTN were on treatment, and about four were optimally controlled. These findings provide a benchmark for NPCDCS, in terms of achievable goals within short periods of follow-up.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"197"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fb/52/ABR-12-197.PMC10492608.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10223596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative Anxiolysis and Analgesic Effect after Premedication with Melatonin and Pregabalin in Total Hip Arthroplasty under Spinal Anaesthesia: A Prospective Comparative Trial. 脊髓麻醉下全髋关节置换术术前应用褪黑素和普瑞巴林后围手术期的焦虑缓解和镇痛效果:一项前瞻性比较试验。

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_323_22

Akash Mishra, Vinod Kumar Srivastava, Ravi Prakash, Neel Kamal Mishra, Jyotsna Agarwal, Shruti Kabi

{"title":"Perioperative Anxiolysis and Analgesic Effect after Premedication with Melatonin and Pregabalin in Total Hip Arthroplasty under Spinal Anaesthesia: A Prospective Comparative Trial.","authors":"Akash Mishra, Vinod Kumar Srivastava, Ravi Prakash, Neel Kamal Mishra, Jyotsna Agarwal, Shruti Kabi","doi":"10.4103/abr.abr_323_22","DOIUrl":"https://doi.org/10.4103/abr.abr_323_22","url":null,"abstract":"Background: Preoperative anxiety plays a critical role in post-operative pain response and other outcomes. Melatonin is a naturally secreted hormone which has anxiolytic, sedative, and analgesic properties. Pregabalin, analogue of gabapentin which has property of anxiolytic and analgesic effects.Materials and methods: Total 96 patients undergoing total hip arthroplasty, divided into 3 groups of 32 each and were given placebo (group I), melatonin 6 mg (group II), and pregabalin 150 mg (group III). Anxiety level, postoperative pain score, sedation level and duration as well as characteristics of spinal anaesthesia were assessed with other vital parameters.Results: Group I showed an increment in the anxiety score from baseline whereas in group II and group III, there was a decline in pre-operative anxiety score from baseline at all the periods of observation and more significantly in group III. Visual analogue scale (VAS) score and total dose of rescue analgesia were highest in group I, but group II and group III were comparable to each other. However, the durations of spinal anaesthesia and motor blockade showed a statistically significant difference with maximum duration in group III followed by II and then I. The level of sedation among the three groups were comparable at all the periods of observation.Conclusions: Pregabalin was found better for perioperative anxiolysis, post-operative analgesia and for prolongation of duration of spinal anaesthesia when compared to melatonin.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"185"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/c4/ABR-12-185.PMC10492595.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10223598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

microRNAs regulate survivin in colorectal cancer patients microrna调节结直肠癌患者的生存素

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_233_22

Mortaza Raeisi, Hadi Chavoshi, Soghra Bornehdeli, Milad Asadi, Roya Dolatkhah, Ayse Caner

{"title":"microRNAs regulate survivin in colorectal cancer patients","authors":"Mortaza Raeisi, Hadi Chavoshi, Soghra Bornehdeli, Milad Asadi, Roya Dolatkhah, Ayse Caner","doi":"10.4103/abr.abr_233_22","DOIUrl":"https://doi.org/10.4103/abr.abr_233_22","url":null,"abstract":"Background: Impaired levels of surviving are associate with increased survival of tumor cells. In this study, we intended to profile the microRNAs (miRNAs) targeting survivin in the tumoral and marginal tissues obtained from Iranian patients with colorectal cancer (CRC).Materials and Methods: Fifty CRC patients of Iranian Azari ethnicity were recruited. The RNA content of the tumoral and marginal tissues was isolated and the transcript levels of miR-34a, miR-16, miR-150, and miR-203a and survivin were determined through quantitative Real-time PCR.Results: The mRNA expression of survivin was significantly increased (fold change = 3.21, P = 0.0029) in the tumoral tissues in comparison to the marginal tissues. There was significant downregulation of miR-16 (fold change = 0.28, P = 0.003) and miR-203a (fold change = 0.36, P = 0.014) in the tumoral samples in comparison to marginal samples. There was an inverse significant correlation (rho = -0.81; P < 0.001) between the expression of miR-203a and mRNA expression of survivin in the tumoral tissues of CRC patients. The mRNA expression of survivin was higher significantly in the tumoral tissues of CRC patients with lymph node metastasis in comparison to those without lymph node metastasis (P = 0.020). In addition, there was a significantly higher miR-203 expression level in the tumoral tissues of CRC patients with lymph node metastasis in comparison to those without lymph node metastasis (P = 0.011).Conclusion: It is suggested that miR-203 plays an oncogenic role in CRC cancer by regulating survivin and lymph node metastasis.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular and antigen detection, phylogenetics, and immunoinformatics study of the zoonotic coronavirus in Iranian diarrheic calves 伊朗腹泻小牛人畜共患冠状病毒的分子和抗原检测、系统发育和免疫信息学研究

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_422_22

MohammadM Ranjbar, Soodeh Enayati, Soodeh Hooshmandi, Shahrzad Ahangarzadeh, Shima Aboutalebian

{"title":"Molecular and antigen detection, phylogenetics, and immunoinformatics study of the zoonotic coronavirus in Iranian diarrheic calves","authors":"MohammadM Ranjbar, Soodeh Enayati, Soodeh Hooshmandi, Shahrzad Ahangarzadeh, Shima Aboutalebian","doi":"10.4103/abr.abr_422_22","DOIUrl":"https://doi.org/10.4103/abr.abr_422_22","url":null,"abstract":"Background: Bovine coronaviruses (BCoVs) are zoonotic diseases that result in substantial economic losses due to mortality, impaired growth, and increased medication expenses in large animals. These viruses pose a risk to children who live beside infected animal, as they can cause diarrhea. This study was dedicated to molecular and antigen detections and phylogenetic and immunoinformatics analysis of zoonotic coronavirus (CoV) in Iran.Materials and Methods: A total of 77 diarrheic samples were collected from Holstein dairy herds in selected provinces of Iran. Samples were tested by capture antibody enzyme-linked immunosorbent assay (ELISA) to detect CoV and reverse transcriptase–polymerase chain reaction (RT–PCR) for verification of detection and also genotyping of spike glycoprotein in CoV-positive samples. After statistical analysis, nucleotide sequence alignment, and nucleotide and protein phylogenetic tree construction, the centralized sequence for vaccine strains was obtained using computationally optimized broadly reactive antigen (COBRA)'s center-of-the-tree (COT) method.Results: Twenty-two (28.5%) and eight (10.3%) of 77 samples were positive according to RT–PCR and ELISA, respectively. (Basic Local Alignment Search Tool) BLAST and phylogenetic analysis revealed that most similar sequences to the Iranian CoV sequence were for European countries. Furthermore, there were strong correlations to other CoVs in humans and wild and domesticated animals. As CoV has variable COT, the most recent strains and COBRA vaccine strains were obtained.Conclusion: Based on the high prevalence of this viral disease in calves and its economic impact on the breeding industry, as well as the potential transmission to humans and correlation with World Health Organization (WHO) One Health approach guidelines, the study emphasizes the importance of implementing preventive strategies such as animal vaccination.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the effectiveness of conventional prostheses against dual-mobility prostheses in the treatment of femoral neck fractures in two separate groups of patients: A clinical trial study 评估两组患者股骨颈骨折常规假体与双活动假体的疗效:一项临床试验研究

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_108_23

Mehdi Motififard, Mohammad Parhamfar, Alireza Hosseini, Mostafa Khashei, Amirmohammad Taravati, Somayeh Shirazinejad, Ali Afsharirad, Amirhossein Sadeghian, AliSherafati Chaleshtori

{"title":"Evaluating the effectiveness of conventional prostheses against dual-mobility prostheses in the treatment of femoral neck fractures in two separate groups of patients: A clinical trial study","authors":"Mehdi Motififard, Mohammad Parhamfar, Alireza Hosseini, Mostafa Khashei, Amirmohammad Taravati, Somayeh Shirazinejad, Ali Afsharirad, Amirhossein Sadeghian, AliSherafati Chaleshtori","doi":"10.4103/abr.abr_108_23","DOIUrl":"https://doi.org/10.4103/abr.abr_108_23","url":null,"abstract":"Background: Femoral neck fracture is a common posttraumatic injury in the elderly. Currently, orthopedic surgeons conducting total hip arthroplasty (THA) for hip fractures have various prosthetic alternatives. Dual-mobility cup THA is recommended for hip fracture patients to reduce prosthesis dislocation. Therefore, the goal of this research is to evaluate the effectiveness of conventional prostheses against dual-mobility prostheses in treating femoral neck fractures in two groups of patients.Materials and Methods: The current clinical investigation involved patients with femoral neck fractures. Among approved 84 patients, 44 and 40 were undergoing conventional THA (group A) and dual-mobility THA (group B), respectively. Patients were observed regularly after surgeries, and the same measurements were performed. The data were assembled and entered into SPSS software (version 25, IBM Corporation, Armonk, NY, USA) and analyzed. In all analyses, a P value of less than 0.05 was considered significant.Results: Eighty-four cases with an average age of 63.97 years were evaluated. In postoperative follow-up, there were no statistically significant differences between the groups in terms of Harris hip score, SF-36, and infection (P > 0.05). However, patients who received conventional implants had more dislocation postoperatively (P = 0.045). Regarding the rehabilitation costs, there were no statistically significant differences between the groups, so the group using the conventional implants incurred a higher cost (P = 0.041).Conclusion: According to the results, both dual mobility and conventional implants had optimal functional outcomes in patients with femoral neck fractures.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of a four-component competing endogenous RNA network reveals potential biomarkers in gastric cancer: An integrated systems biology and experimental investigation 四组分竞争内源性RNA网络的分析揭示了胃癌的潜在生物标志物:综合系统生物学和实验研究

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_185_23

Parvaneh Nikpour, Sadra Salehi-Mazandarani

{"title":"Analysis of a four-component competing endogenous RNA network reveals potential biomarkers in gastric cancer: An integrated systems biology and experimental investigation","authors":"Parvaneh Nikpour, Sadra Salehi-Mazandarani","doi":"10.4103/abr.abr_185_23","DOIUrl":"https://doi.org/10.4103/abr.abr_185_23","url":null,"abstract":"Background: Gastric cancer (GC) is a common and deadly cancer worldwide. Molecular changes underlying the development of GC are not thoroughly understood. Therefore, we constructed and analyzed a novel four-component competing endogenous RNA (ceRNA) network to introduce plausible diagnostic and prognostic biomarkers in GC. Materials and Methods: Transcriptomics and circular RNA (circRNA) data were retrieved from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) databases, respectively. After batch effect correction, differential expression analysis, and interaction prediction, a ceRNA network including long noncoding RNAs (lncRNAs), circular RNAs (circRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) was established. Enrichment analyses were performed, and a protein–protein interaction (PPI) network was constructed. Furthermore, a subnetwork was extracted, and using the quantitative real-time polymerase chain reaction (qRT-PCR) method, the expression changes of two hub ceRNAs were examined. Finally, survival analysis was performed to identify potential prognostic RNAs. Results: A four-component ceRNA network containing 822 nodes and 1365 edges was constructed. Enrichment analyses unveiled important signaling pathways and gene ontologies such as neuroactive ligand–receptor interaction and axonogenesis. The PPI network showed the interactions among mRNAs of the ceRNA network. qRT-PCR indicated downregulation of EPHA5 and SNAP91 mRNAs in GC compared to control tissues. Survival analyses revealed eight mRNAs and one lncRNA as potential prognostic biomarkers in GC. Conclusion: The established four-component network of ceRNAs in GC reveals a comprehensive view of the molecular and cellular characteristics of GC progression, which can be considered as a basis to examine and validate potential diagnostic and prognostic biomarkers as well as therapeutic targets.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135317891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Vitamin D Supplement on the Relapsing Incidence of Rhinosinusitis with Nasal Polyposis after Fuctional Endoscpoic Sinus Surgery. 补充维生素D对鼻窦炎合并鼻息肉术后复发率的影响。

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_237_21

Hossein Ghazavi, Sayed Mostafa Hashemi, Samaneh Jafari

{"title":"The Effect of Vitamin D Supplement on the Relapsing Incidence of Rhinosinusitis with Nasal Polyposis after Fuctional Endoscpoic Sinus Surgery.","authors":"Hossein Ghazavi, Sayed Mostafa Hashemi, Samaneh Jafari","doi":"10.4103/abr.abr_237_21","DOIUrl":"https://doi.org/10.4103/abr.abr_237_21","url":null,"abstract":"Background: Nasal polyp (NP) is the most common benign tumor that can cause nasal obstruction and more annoying problems in patients. Recently, investigators have been focusing on complementary therapies alone or in conjunction with endoscopic nasal and sinus surgery. However, given the association of Vitamin D (VD) deficiency and chronic rhinosinusitis with nasal polyposis (CRSwNP) in previous studies, it may be possible to prevent the recurrence of NP and the development of rhinosinusitis by controlling serum levels of VD and maintaining it at a normal level. The current study aimed to investigate the efficacy of VD supplementation in preventing CRSwNP recurrence after endoscopic surgery.Materials and methods: This clinical trial composed of vitamin D deficient patients with CRSwNP who were candidates for endoscopic sinus surgery in two groups of cases and controls. After endoscopic sinus surgery for all patients, we administered VD supplementation (50,000 IU) once a week for 8 weeks for cases and no further intervention for controls. The severity of symptoms was assessed using Sino-nasal outcome test (SNOT-22) and NP recurrence and recorded pre- and postintervention.Results: The findings indicated a higher mean change of SNOT-22 in the case group compared to that of the control group (36.03 ± 10.71 vs. 29.90 ± 11.99; P = 0.041). Moreover, the percentage of NP recurrence in cases was lower than controls; so that receiving VD supplementation has significantly reduced the chance of NP recurrence (odd ratio [95% confidence interval]: 0.298 [0.099-0.900]; P = 0.032).Conclusion: According to the result of the study, the administration of VD supplementation after endoscopic sinus surgery can reduce the severity of CRSwNP symptoms and NP recurrence significantly.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/aa/72/ABR-12-29.PMC10086644.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9360026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary and Sleep Quality Association in Hemodialysis Patients. 血液透析患者饮食与睡眠质量的关系。

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_244_22

Mojgan Mortazavi, Mohammad Hossein Rouhani, Shiva Seirafian, Reyhane Motamedifard, Mohsen Hosseini

{"title":"Dietary and Sleep Quality Association in Hemodialysis Patients.","authors":"Mojgan Mortazavi, Mohammad Hossein Rouhani, Shiva Seirafian, Reyhane Motamedifard, Mohsen Hosseini","doi":"10.4103/abr.abr_244_22","DOIUrl":"https://doi.org/10.4103/abr.abr_244_22","url":null,"abstract":"Background: Poor sleep quality is a common issue among patients with end-stage renal disease (ESRD) who undergo dialysis. Nutritional habits are associated with sleep hygiene in patients undergoing dialysis. The objective of this study was to examine the potential correlation between nutritional status and sleep quality in individuals receiving hemodialysis treatment.Materials and methods: This cross-sectional study included 160 hemodialysis patients. A food frequency questionnaire (FFQ) was used to measure food intake in participants. The Persian-validated version of the Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality. Patients were classified as poor or good sleepers with a PSQI score of <5 and >5, respectively.Results: Eighty-four percent of hemodialysis patients had bad sleep hygiene. There was a significant association between sleep quality and educational status and age (P < 0.001). Poor sleepers were older (61.65 years versus 51.12) and less educated (31.1% versus 4%). However, there was no significant difference in the intake of micro- and macronutrients between poor and good sleepers (P > 0.05).Conclusion: The results of this study suggest that sleep quality has no significant relationship with nutrient intake in hemodialysis patients. Demographic factors, such as age and educational status, have played a more effective role than nutritional factors in patients' sleep quality.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"189"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/b4/ABR-12-189.PMC10492622.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10589167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comprehensive Review of Identification Methods for Pathogenic Yeasts: Challenges and Approaches. 病原菌鉴定方法综述:挑战与途径。

Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_375_22

Hamid Morovati, Mohammad Kord, Kazem Ahmadikia, Saba Eslami, Masoumeh Hemmatzadeh, Kian M Kurdestani, Mohammadreza Khademi, Sima Darabian

{"title":"A Comprehensive Review of Identification Methods for Pathogenic Yeasts: Challenges and Approaches.","authors":"Hamid Morovati, Mohammad Kord, Kazem Ahmadikia, Saba Eslami, Masoumeh Hemmatzadeh, Kian M Kurdestani, Mohammadreza Khademi, Sima Darabian","doi":"10.4103/abr.abr_375_22","DOIUrl":"https://doi.org/10.4103/abr.abr_375_22","url":null,"abstract":"Given the increasing incidence of yeast infections and the presence of drug-resistant isolates, accurate identification of the pathogenic yeasts is essential for the management of yeast infections. In this review, we tried to introduce the routine and novel techniques applied for yeast identification. Laboratory identification methods of pathogenic yeast are classified into three categories; I. conventional methods, including microscopical and culture-base methods II. biochemical/physiological-processes methods III. molecular methods. While conventional and biochemical methods require more precautions and are not specific in some cases, molecular diagnostic methods are the optimum tools for diagnosing pathogenic yeasts in a short time with high accuracy and specificity, and having various methods that cover different purposes, and affordable costs for researchers. Nucleotide sequencing is a reference or gold standard for identifying pathogenic yeasts. Since it is an expensive method, it is not widely used in developing countries. However, novel identification techniques are constantly updated, and we recommend further studies in this field. The results of this study will guide researchers in finding more accurate diagnostic method(s) for their studies in a short period of time.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"187"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/55/ABR-12-187.PMC10492613.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10589170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0