Advanced Biomedical Research最新文献

筛选
英文 中文
Effect of Music During General Anesthesia on Anesthetic Consumption During Vitrectomy Surgery. 玻璃体切割手术中全身麻醉时音乐对麻醉消耗的影响。
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_444_22
Ardeshir Tajbakhsh, Sohrab Salimi, Narsis Daftarian, Dariush Abtahi
{"title":"Effect of Music During General Anesthesia on Anesthetic Consumption During Vitrectomy Surgery.","authors":"Ardeshir Tajbakhsh,&nbsp;Sohrab Salimi,&nbsp;Narsis Daftarian,&nbsp;Dariush Abtahi","doi":"10.4103/abr.abr_444_22","DOIUrl":"https://doi.org/10.4103/abr.abr_444_22","url":null,"abstract":"<p><strong>Background: </strong>Controversy remains about the positive role of music during general anesthesia and postoperative recovery. We, therefore, tested the hypothesis that intraoperative exposure to classical music reduces the propofol necessary to maintain the bispectral index (BIS) close to 50 during vitrectomy surgery.</p><p><strong>Materials and methods: </strong>This double-blind clinical study is evaluating 50 patients undergoing vitrectomy surgery under general anesthesia. Patients were randomly assigned to music and white noise groups, and relevant sounds were played to patients after induction of anesthesia. The two groups were compared for the use of propofol as an anesthetic to maintain a BIS near 50 and for postoperative pain, anxiety, nausea, and vomiting.</p><p><strong>Results: </strong>Propofol consumption to maintain the set BIS score was much lower in the music group than in the white noise group (78.72 ± 25.76 microgram/kg/min and 117.91 ± 36.78 microgram/kg/min, respectively, <i>P</i>-value = 0.000). Postoperative pain scores were also much lower in the music group than in the white noise group (<i>P</i>-value = 0.000) and anxiety levels between these two groups did not differ (<i>P</i>-value = 0.870). No patient in the music group had complaints of postoperative nausea and vomiting (PONV) compared to six patients in the white noise group (<i>P</i>-value = 0.011).</p><p><strong>Conclusions: </strong>Listening to music during general anesthesia for vitrectomy surgery can reduce the use of anesthetics, postoperative pain, and PONV. Further, controlled studies are necessary to confirm our results.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4d/eb/ABR-12-59.PMC10186032.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9483849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Lymphovascular Space Invasion (LVSI) with Histological Tumor Grade and Myometrial Invasion in Endometrial Carcinoma: A Review Study. 子宫内膜癌淋巴血管间隙浸润(LVSI)与组织学肿瘤分级和子宫肌层浸润的关系综述
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_52_23
Azita Rafiee, Fereshteh Mohammadizadeh
{"title":"Association of Lymphovascular Space Invasion (LVSI) with Histological Tumor Grade and Myometrial Invasion in Endometrial Carcinoma: A Review Study.","authors":"Azita Rafiee,&nbsp;Fereshteh Mohammadizadeh","doi":"10.4103/abr.abr_52_23","DOIUrl":"https://doi.org/10.4103/abr.abr_52_23","url":null,"abstract":"<p><p>Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma. LVSI is considered an independent poor prognostic factor in endometrial carcinoma. Based on the importance of LVSI, this study aimed to discuss the association of LVSI with tumor grade and MMI. A search of PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane Library was carried out to collect related studies. Consequently, most studies showed that LVSI is significantly associated with higher histologic grade and deep MMI.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"159"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/0d/ABR-12-159.PMC10410422.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9981625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of using standard and high-resolution exposure modalities of cone-beam computed tomography (CBCT) system for dental implants dimension measurements 使用锥形束计算机断层扫描(CBCT)系统的标准和高分辨率暴露模式对种植体尺寸测量的影响
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_386_21
Hossein Taheri, Mojdeh Mehdizadeh, Parvaneh Rostamzadeh
{"title":"Impact of using standard and high-resolution exposure modalities of cone-beam computed tomography (CBCT) system for dental implants dimension measurements","authors":"Hossein Taheri, Mojdeh Mehdizadeh, Parvaneh Rostamzadeh","doi":"10.4103/abr.abr_386_21","DOIUrl":"https://doi.org/10.4103/abr.abr_386_21","url":null,"abstract":"Background: This study aimed to analyze the effects of standard and high-resolution exposures on the diagnostic accuracy of CBCT in the evaluation of dental implant dimensions.Materials and Methods: A descriptive–analytical study was carried out on 40 dry human mandibles with appropriate ridge quality based on panoramic radiography. CBCT (Soredex, Cranex 3D, Finland) with a large field of view (FOV) and CMOS flat panel detector were used. CBCT with standard and a high resolution was performed in each mandible. Axial images, reconstructed by OnDemand 3D software, were processed to prepare cross-sectional images from the areas marked by gutta-percha, and then measured by a ruler with an accuracy of 0.01 millimeter in the computer. Measurements were recorded by two observers and the obtained data were compared with the real ones.Results: The results showed suitable repeatability in radiologic measurements (r = 0.971), which is indicative of the high reliability of intraobserver measurement. The measurement of width with high-resolution exposure indicated a significant difference with the real condition (P < 0.001); however, this difference was not significant in the case of standard resolution (P > 0.05). Measurement of height with high resolution showed a significant difference with the real condition in the right mandible (P = 0.04) and left mandible (P = 0.05); however, this difference was not significant in standard resolution (P > 0.05).Conclusion: Based on our findings, the standard CBCT resolution modality is suggested for dental implant images due to its higher accuracy than high-resolution methods for diagnosing the implant dimensions.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"282 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Magnetic Resonance Imaging (MRI) Findings following posterior Sagital Ano-Recto Plasty (PSARP) in Severe Incontinent Children with High Imperforate Anus (IA) 后矢状肛门-直肠成形术(PSARP)治疗严重尿失禁伴肛门高度闭锁(IA)患儿的磁共振成像(MRI)评价
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_207_22
Mehrdad Hosseinpour, Bijan Ziyaee, Masoud Nazem, Maryam Riahinezhad
{"title":"Evaluation of Magnetic Resonance Imaging (MRI) Findings following posterior Sagital Ano-Recto Plasty (PSARP) in Severe Incontinent Children with High Imperforate Anus (IA)","authors":"Mehrdad Hosseinpour, Bijan Ziyaee, Masoud Nazem, Maryam Riahinezhad","doi":"10.4103/abr.abr_207_22","DOIUrl":"https://doi.org/10.4103/abr.abr_207_22","url":null,"abstract":"Background: The aim of this study was to evaluate pelvic MRI accuracy for measurement of anatomical land marks in severe fecal incontinent (FI) children with high imperforate anus (IA).Materials and Methods: A total of 80 children (40 cases and 40 controls) aged more than 4 years with severe FI were assessed. Magnetic resonance imaging was performed by a radiologist with the same device. For pelvic anatomical land marks measurement, we measured the ano-rectal angel and hiatal/pc ratio.Results: The mean of ano-rectal angel was 118.67 ± 25.2 mm in cases and 132.07 ± 13.8 mm in control group (P = .004). H/PCR was 0.63 ± 0.05 in cases and 0.62 ± 0.45 in controls (P = NS). There was no significant correlation between [INSIDE:1] (r = 0.25, P = 0.36) or ano-rectal angle measurement (r = 0.16, P = 0.05) and FI score in patients with severe FI.Conclusions: Pelvic magnetic resonance imaging could be accurately used is measuring the ano-rectal angle is high IA children with severe FI which leads to selected patients who may have benefits of reoperation.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135102668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of spinocerebellar ataxia autosomal recessive 21 presented with liver disease 一个罕见的脊髓小脑性共济失调常染色体隐性遗传21表现为肝脏疾病
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_139_22
Hosein Saneian, Narges Zare, Majid Khademian
{"title":"A rare case of spinocerebellar ataxia autosomal recessive 21 presented with liver disease","authors":"Hosein Saneian, Narges Zare, Majid Khademian","doi":"10.4103/abr.abr_139_22","DOIUrl":"https://doi.org/10.4103/abr.abr_139_22","url":null,"abstract":"Spinocerebellar ataxia autosomal recessive 21 is known as a very rare disease. It is caused by a homozygous mutation in the SCYL1 gene on chromosome 11q13 and presented in early childhood. The common presentations of this disease are recurrent episodes of liver failure, chronic liver fibrosis, cerebellar atrophy in early childhood, late onset of learning disabilities, and peripheral neuropathy. Diagnosis of spinocerebellar ataxia autosomal recessive 21 is challenging, especially due to the variety of clinical presentations. In the current study, we present an 11-year-old girl diagnosed with spinocerebellar ataxia autosomal recessive 21. She had multiple episodes of acute hepatic failure with later presentations of neurological dysfunctions. The diagnosis of spinocerebellar ataxia autosomal recessive 21 was made by genetic testing.","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135212310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Effectiveness of Two Types of Commercial Endotracheal Tube Holders, with the Conventional Method in a Manikin Model. 两种商用气管插管支架与传统方法在人体模型上的有效性比较。
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_192_21
Mehdi Nasr Isfahani, Alireza Abootalebi, Khatere Ghaznavi, Leila Kamali Dolatabadi
{"title":"Comparison of the Effectiveness of Two Types of Commercial Endotracheal Tube Holders, with the Conventional Method in a Manikin Model.","authors":"Mehdi Nasr Isfahani,&nbsp;Alireza Abootalebi,&nbsp;Khatere Ghaznavi,&nbsp;Leila Kamali Dolatabadi","doi":"10.4103/abr.abr_192_21","DOIUrl":"https://doi.org/10.4103/abr.abr_192_21","url":null,"abstract":"<p><strong>Background: </strong>Endotracheal intubation is employed to create a safe airway in patients requiring mechanical ventilation. The relatively high prevalence rate of unplanned displacement of the endotracheal tube (ETT) can be associated with serious complications. This study was conducted to evaluate the effectiveness of a newly designed tube holder in Iran (Irafit), the Thomas ETT holder and the traditional method using adhesive tape.</p><p><strong>Materials and methods: </strong>The present manikin-based study was performed on the human mannequin. For this purpose, the mannequin was first subjected to oral intubation by a skilled emergency medicine specialist. Then, three methods of adhesive tape, Irafit-ETT holder, and Thomas-ETT holder were used. The mean of displacement in width of the mouth, length of the ETT, and depth as well as ETT removal was recorded.</p><p><strong>Results: </strong>The results of the present study revealed that the displacement in depth was significantly less in the Irafit-ETT holder as compared with the other two groups following the application of a tug (<i>P</i> < 0.001). The displacement in the length of the ETT with and without the application of a tug was significantly less in the Irafit-ETT holder and Thomas-ETT holder groups as compared with the adhesive tape group (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>According to the results of the present study, it can be stated that both ETT holder devices (Thomas vs. Irafit) were not distinct in terms of displacements in length and width; however, the Iranian model was more successful in minimizing the displacement in depth.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"30"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/85/6d/ABR-12-30.PMC10086637.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9298835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Success Rate and Safety of Nasotracheal Intubation by Conventional and Finger-Guided Method in Patients Undergoing Maxillofacial Surgery. 颌面外科常规与指路鼻气管插管成功率及安全性比较。
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_255_21
Seyed Jalal Hashemi, Hamidreza Shetabi, Reihanak Talakoub, Avishan Aminizad
{"title":"Comparison of Success Rate and Safety of Nasotracheal Intubation by Conventional and Finger-Guided Method in Patients Undergoing Maxillofacial Surgery.","authors":"Seyed Jalal Hashemi,&nbsp;Hamidreza Shetabi,&nbsp;Reihanak Talakoub,&nbsp;Avishan Aminizad","doi":"10.4103/abr.abr_255_21","DOIUrl":"https://doi.org/10.4103/abr.abr_255_21","url":null,"abstract":"<p><strong>Background: </strong>Different techniques have been introduced to reduce the complications of nasotracheal intubation. The aim of this study was to compare the incidence of nasotracheal intubation complications in finger-guided and conventional methods.</p><p><strong>Materials and methods: </strong>In this double-blind randomized trial study, 70 patients who were candidates for oral and maxillofacial surgery who required nasal intubation were included in the study finally of which 33 patients with conventional method and 35 patients with finger-guided tubes in the nasopharynx were analyzed at the end of the study. Variables such as success rate, hemodynamic response, and complications of intubation were compared between the two groups.</p><p><strong>Results: </strong>There was no significant difference between the two groups in terms of hemodynamic response to intubation (<i>P</i> > 0.05). There was a significant difference between the two groups in terms of success in tracheal intubation (<i>P</i> < 0.05). There was a significant difference between the two groups in terms of epistaxis immediately after intubation (<i>P</i> < 0.05). There was no significant difference between the two groups in terms of nasal turbine fractures (<i>P</i> > 0.05). However, the frequency of submucosal intubation in the conventional method was significantly higher than the other group (<i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>Nasotracheal intubation using the finger guiding technique in the nasopharynx is associated with a higher success rate and less complications after intubation such as epistaxis and submucosal intubation compared to the conventional method.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"35"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/93/dd/ABR-12-35.PMC10086639.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9305338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Fetal and Maternal Outcomes in Chorion Villus Sampling (CVS). 绒毛膜绒毛取样(CVS)中胎儿和母体结局的评估。
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_229_22
Minoo Movahedi, Farinaz Farahbod, Elahe Zarean, Maryam Hajihashemi, Fedyeh Haghollahi, Mehri Farahmand
{"title":"Evaluation of Fetal and Maternal Outcomes in Chorion Villus Sampling (CVS).","authors":"Minoo Movahedi,&nbsp;Farinaz Farahbod,&nbsp;Elahe Zarean,&nbsp;Maryam Hajihashemi,&nbsp;Fedyeh Haghollahi,&nbsp;Mehri Farahmand","doi":"10.4103/abr.abr_229_22","DOIUrl":"https://doi.org/10.4103/abr.abr_229_22","url":null,"abstract":"<p><strong>Background: </strong>Chorionic villus sampling (CVS) is one of the invasive diagnostic methods used to diagnose chromosomal, genetic, and metabolic diseases in the embryonic period. The use of this method is associated with maternal and fetal consequences, the most serious of which is abortion. Therefore, the present study was conducted to investigate the incidence of these consequences and the factors affecting the incidence of abortion.</p><p><strong>Materials and methods: </strong>A cross-sectional study was performed on 98 pregnant women with CVS indications. Maternal and fetal outcomes including abortion, vaginal bleeding, subchorionic hematoma, premature rupture of membrane (PROM), chorioamnionitis, preterm delivery, limb abnormality, fetal growth retardation, and preeclampsia were recorded.</p><p><strong>Results: </strong>The results of the present study showed that the incidence of fetal outcomes including fetal growth failure, premature rupture of membranes, abortion, and limb abnormalities was 4.1%, 7.1%, 3.1%, and 1%, and the incidence of maternal outcomes including preterm delivery, subchorionic hematoma, preeclampsia, and hemorrhage was 14.3%, 3.1%, 6.1%, and 10.2%, respectively. In addition, a decrease in free BHCG and an increase in NT were significantly associated with the occurrence of abortion (OR: 0.11 and 4.25, respectively, <i>P</i> value < 0.05).</p><p><strong>Conclusion: </strong>It should be noted that due to a long time between placental sampling and the occurrence of vaginal bleeding, premature rupture of membrane, and preterm delivery, it seems that placental sampling has no effect. In addition, only a decrease in free BHCG or an increase in NT significantly increased the chance of miscarriage.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"133"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6a/3a/ABR-12-133.PMC10331521.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9814970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Relationship between Pregnancy-Associated Plasma Protein A (PAPP-A) and Pregnancy Outcomes. 妊娠相关血浆蛋白A (PAPP-A)与妊娠结局关系的评价
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_344_21
Minoo Movahedi, Somayeh Khanjani, Zahra Shahshahan, Maryam Hajihashemi, Farinaz Farahbod, Elaheh Shahsavandi
{"title":"Evaluation of the Relationship between Pregnancy-Associated Plasma Protein A (PAPP-A) and Pregnancy Outcomes.","authors":"Minoo Movahedi,&nbsp;Somayeh Khanjani,&nbsp;Zahra Shahshahan,&nbsp;Maryam Hajihashemi,&nbsp;Farinaz Farahbod,&nbsp;Elaheh Shahsavandi","doi":"10.4103/abr.abr_344_21","DOIUrl":"https://doi.org/10.4103/abr.abr_344_21","url":null,"abstract":"<p><strong>Background: </strong>In the current study, we aimed to evaluate the association between pregnancy-related plasma protein-A (PAPP-A) levels measured in the first trimester and pregnancy outcomes.</p><p><strong>Materials and methods: </strong>This is a descriptive-analytical study that was performed in 2019--2021 on 1061 pregnant women in their first trimester. Demographic and basic information of all women were collected. These data included age, weight, parity, and date of delivery. Then the quantity of PAPP-A was recorded in three groups including less than 0.5 MOM, 0.5 to 2.5 MOM, and more than 2.5 MOM.</p><p><strong>Results: </strong>Data of 1061 women were analyzed. 900 women (84.8%) had term delivery and 155 women (14.6%) had pre-term deliveries. PAPP-A levels were normal in 83.4% of women. BMI and number of pregnancies had significant relationships with PAPP-A (<i>p</i> < 0.001, <i>P</i> = 0.03 respectively). The mean BMI in mothers with PAPP-A higher than 2.5 was significantly more than mothers with normal or lower PAPP-A levels (26.2 ± 31, <i>P</i> = 0.04). The frequency of term labor in mothers with normal PAPP-A was higher than other mothers (86.3%, <i>P</i> = 0.04). The frequency of preeclampsia in recent pregnancies in mothers with normal PAPP-A was significantly lower than other mothers (<i>p</i> < 0.001) and the frequency of abortions in recent pregnancies in mothers with PAPP-A less than 0.5 was significantly higher than mothers with normal or elevated PAPP-A (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Mothers with low PAPP-A levels are more likely to have poor pregnancy outcomes such as abortion, pre-term labor, and preeclampsia.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"91"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e3/88/ABR-12-91.PMC10241634.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions. 乳腺闪烁成像在可疑(乳腺影像报告与数据系统IV)乳腺病变中的应用。
Advanced Biomedical Research Pub Date : 2023-01-01 DOI: 10.4103/abr.abr_347_21
Ali Reza Azarpeikan, Ramesh Omranipour, Habibollah Mahmoodzadeh, Seyed Rouhollah Miri, Narjes Mohammadzadeh, Farhang Derakhshan, Saeed Farzanefar, Mehrshad Abbasi
{"title":"Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions.","authors":"Ali Reza Azarpeikan,&nbsp;Ramesh Omranipour,&nbsp;Habibollah Mahmoodzadeh,&nbsp;Seyed Rouhollah Miri,&nbsp;Narjes Mohammadzadeh,&nbsp;Farhang Derakhshan,&nbsp;Saeed Farzanefar,&nbsp;Mehrshad Abbasi","doi":"10.4103/abr.abr_347_21","DOIUrl":"https://doi.org/10.4103/abr.abr_347_21","url":null,"abstract":"<p><strong>Background: </strong>The surgery for a breast imaging-reporting and data system (BIRADS) IV lesions needs imaging or pathology supporting data. The roll of breast scintigraphy for this purpose is unclear.</p><p><strong>Materials and methods: </strong>In a prospective design, 16 patients with 25 BIRADS IV lesions who were scheduled for surgery were included. Before the surgery, breast scintigraphy was done using a nondedicated dual head gamma camera in the prone position employing a shaped foam pad providing imaging at breast pendulous position. Twenty mCi<sup>99m</sup> Tc methoxy-isobutyl-isonitrile was injected and two 15 and 60-min delayed imaging were done (anterior, bilateral, and single photon emission computed tomography [SPECT] projections). Pathology reports were collected and tumor to nontumor uptake ratio (T/NT) was analyzed, accordingly.</p><p><strong>Results: </strong>Out of all lesions, 12 were malignant (invasive ductal and lobular carcinoma ductal carcinoma <i>in situ</i>). At 15 min, T/NT was insignificantly higher in the malignant compared to benign lesions (22.8 ± 23.9 vs. 10.1 ± 10.1; <i>P</i> = 0.109). The optimal T/NT cutoff for discrimination of malignant and benign lesions was 20. Only 1 out of 13 benign lesions presented uptake >20 (7.7%; false-positive rate; <i>P</i> = 0.047). The diagnostic accuracy, sensitivity, and specificity for T/NT calculated at 0.68, 0.42, and 0.92, respectively. The T/NT at 60 min remained unchanged for either benign or malignant lesions (22.3 ± 30.2 vs. 11.7 ± 17.1; <i>P</i> = 0.296).</p><p><strong>Conclusions: </strong>Breast scintigraphy with general purpose gamma camera employing SPECT imaging may assist the selection of BIRADS IV lesions in need for surgery. All uptake positive cases should undergo surgery and decision for uptake negative cases should be made based on other data.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"86"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/d5/ABR-12-86.PMC10241632.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书