{"title":"Total intravenous anaesthesia with remimazolam in a patient with progressive supranuclear palsy","authors":"T. Oshida, T. Taniguchi","doi":"10.1002/anr3.70011","DOIUrl":"https://doi.org/10.1002/anr3.70011","url":null,"abstract":"<p>Progressive supranuclear palsy is a neurodegenerative disease of unknown aetiology; few reports address its anaesthetic management. Remimazolam, a recently approved short-acting benzodiazepine, was used in combination with remifentanil for total intravenous anaesthesia during open cholecystectomy in a patient with progressive supranuclear palsy. Due to its cardiovascular stable profile and rapid reversibility with flumazenil, remimazolam may serve as a viable option for general anaesthesia in patients with this condition.</p>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anr3.70011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143919891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of rapid onset methaemoglobinaemia associated with local anaesthetic use","authors":"K. Zadeh, J. Bui, J. Lakshay, V. Vanam","doi":"10.1002/anr3.70013","DOIUrl":"https://doi.org/10.1002/anr3.70013","url":null,"abstract":"<div>\u0000 \u0000 <p>Methaemoglobinaemia is a rare but serious condition which can arise due to the administration of local anaesthetic agents. A 36-year-old woman with metastatic oesophageal adenocarcinoma experienced a rapid onset of methaemoglobinaemia following airway topicalisation with lidocaine and benzocaine sprays for bronchoscopy. The patient was treated with supplementary oxygen, non-invasive respiratory support, methylene blue and ascorbic acid. Early diagnosis and timely treatment of methaemoglobinaemia can result in rapid clinical improvement and prevent long-term complications.</p>\u0000 </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. L. Katsin, M. Glebov, T. Nir, Y. Portnoy, M. J. Katsin, H. Berkenstadt, D. Orkin
{"title":"Pulmonary embolism of haemostatic material during paediatric neurosurgery","authors":"M. L. Katsin, M. Glebov, T. Nir, Y. Portnoy, M. J. Katsin, H. Berkenstadt, D. Orkin","doi":"10.1002/anr3.70010","DOIUrl":"https://doi.org/10.1002/anr3.70010","url":null,"abstract":"<div>\u0000 \u0000 <p>A 7-year-old boy with juvenile pilocytic astrocytoma experienced sudden haemodynamic collapse after significant venous bleeding and the application of absorbable haemostatic gelatin sponge. Following successful resuscitation, intra-operative transthoracic echocardiography revealed acute right ventricular failure. Subsequent computed tomography angiography confirmed the diagnosis of a massive pulmonary embolism. Extracorporeal membrane oxygenation was initiated and catheter thrombectomy was performed. The patient had a rapid and complete recovery. This case underscores the importance of vigilance and multidisciplinary teamwork in the management of rare but life-threatening complications.</p>\u0000 </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gastric ultrasound to assess the prokinetic efficacy of erythromycin in a patient taking glucagon-like peptide-1 receptor agonists","authors":"N. S. Sidhu","doi":"10.1002/anr3.70008","DOIUrl":"https://doi.org/10.1002/anr3.70008","url":null,"abstract":"<p>Glucagon-like peptide-1 receptor agonists slow gastric emptying and may increase aspiration risk. Recent guidelines suggest using prokinetic agents pre-operatively, but no studies have assessed the efficacy of erythromycin for this purpose. We present a 53-year-old man (weight 110 kg) taking liraglutide and undergoing elective knee arthroscopy. Despite 19 h of fasting and withholding liraglutide, gastric ultrasound revealed a grade 3 antrum with solid content. Intravenous erythromycin 300 mg was administered, causing transient gastrointestinal symptoms. A repeat ultrasound 15 min later showed reduced solid content, although the antrum was not convincingly empty. As the patient declined neuraxial anaesthesia without sedation, a modified rapid sequence induction was performed. An ultrasound scan at the completion of surgery confirmed an empty stomach, and recovery was uneventful. This is the first documented case using gastric ultrasound to assess the effect of erythromycin on a patient taking a glucagon-like peptide-1 receptor agonist. While erythromycin achieved its desired effect within 100 min, the optimal timing for prokinetic administration and subsequent ultrasound assessment remains uncertain. Gastric ultrasound may refine risk stratification and guide prokinetic use for these patients. Further research is needed to determine optimal erythromycin dosing, time to desired effect and side effects to optimise peri-operative management.</p>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anr3.70008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kuroki, A. Narisawa, Y. Yokoyama, T. Hayasaka, Y. Onodera, M. Okada, H. Toyama
{"title":"Prolonged anaphylactic circulatory failure caused by blood transfusion during general anaesthesia","authors":"M. Kuroki, A. Narisawa, Y. Yokoyama, T. Hayasaka, Y. Onodera, M. Okada, H. Toyama","doi":"10.1002/anr3.70009","DOIUrl":"https://doi.org/10.1002/anr3.70009","url":null,"abstract":"<p>Blood transfusion is one of the causes of anaphylaxis during general anaesthesia. In most cases, adrenaline administration quickly alleviates circulatory failure and its continuous administration for days is very rare. We present the case of a 79-year-old man who experienced prolonged anaphylactic circulatory failure with increased histamine and tryptase concentrations following laparoscopic total gastrectomy, during which he received a blood transfusion. He developed hypotension soon after the initiation of blood transfusion during surgery. We immediately administered intravenous adrenaline, followed by a continuous adrenaline infusion to stabilise the circulation. Circulatory failure recurred and itchy wheals appeared when the adrenaline dose was reduced necessitating continuous adrenaline administration for > 24 h. The histamine and tryptase serum concentrations increased when the adrenaline dose was reduced. The timing of anaphylaxis onset and skin test results excluded rocuronium, cefazolin, ropivacaine and propofol as causes of the anaphylaxis. Therefore, the blood transfusion was the most likely cause. For anaphylaxis due to common causes, boluses of adrenaline often restore the circulation shortly after onset. However, transfusion-induced anaphylaxis, as in this case, can require prolonged infusion of adrenaline because of the lack of allergen clearance. For such cases, careful follow-up is very important.</p>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anr3.70009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fascial plane blocks and conscious sedation for a patient undergoing minimally invasive hemithyroidectomy","authors":"M. M. Alseoudy, I. A. Elzahaby, D. A. Elebedy","doi":"10.1002/anr3.70007","DOIUrl":"https://doi.org/10.1002/anr3.70007","url":null,"abstract":"<div>\u0000 \u0000 <p>Fascial plane blocks for thoracic and neck surgery provide not only peri-operative analgesia but also serve as an effective alternative to general anaesthesia when combined with procedural sedation. Hemithyroidectomies are commonly performed by an open technique involving a transverse neck incision. Minimally invasive endoscopic approaches can offer cosmetic benefits, quicker recovery and reduced need for analgesia. Avoiding general anaesthesia may reduce complications, such as pulmonary atelectasis and cardiovascular instability, which may be of benefit to patients at increased risk. We describe the use of a combination of fascial plane blocks (superficial cervical plexus block, clavipectoral fascia plane block, interpectoral plane block and pectoserratus plane block) and dexmedetomidine sedation for a 65-year-old patient who had previously experienced accidental awareness under general anaesthesia and was very keen to avoid another general anaesthetic. The procedure was uneventful, with minimal bleeding and stable respiratory and haemodynamic parameters throughout. The patient was extremely satisfied with the anaesthetic technique and the cosmetic results of the surgery. We propose that fascial plane blocks along with dexmedetomidine sedation can be an effective alternative to general anaesthesia for endoscopic hemithyroidectomy in selected patients.</p>\u0000 </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Sindwani, S. L. Ronanki, A. Yadav, U. Dhingra, D. Tempe, V. Pamecha, N. Mohapatra
{"title":"Managing post-reperfusion syndrome in domino liver transplantation for familial amyloidotic polyneuropathy","authors":"G. Sindwani, S. L. Ronanki, A. Yadav, U. Dhingra, D. Tempe, V. Pamecha, N. Mohapatra","doi":"10.1002/anr3.70006","DOIUrl":"https://doi.org/10.1002/anr3.70006","url":null,"abstract":"<div>\u0000 \u0000 <p>Familial amyloidotic polyneuropathy is a rare genetic disorder caused by transthyretin mutations, leading to multi-organ dysfunction, with a significant impact on the nervous and cardiovascular systems. Domino liver transplantation is a unique strategy which increases donor organ availability by transplanting the explanted liver from a patient with familial amyloidotic polyneuropathy into another patient. This report describes a 37-year-old patient with familial amyloidotic polyneuropathy who underwent a living donor liver transplantation as part of a domino liver transplantation, emphasising the lessons learnt about the role of isoprenaline for managing the post-reperfusion syndrome and the considerations regarding prophylactic pacemaker insertion. She developed severe bradycardia following anaesthesia induction and again during graft reperfusion, which was refractory to atropine but successfully managed with isoprenaline. On postoperative day 20, she experienced severe bradycardia which was unresponsive to medical management, necessitating a temporary pacemaker, followed by a permanent pacemaker on postoperative day 26. This case highlights the role of isoprenaline as a preferred agent for managing bradyarrhythmia and conduction blocks during liver graft reperfusion. Additionally, it highlights the potential need for prophylactic pacemaker insertion in select patients with subclinical conduction abnormalities, as stressors, such as liver transplantation, can unmask life-threatening arrhythmias.</p>\u0000 </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hybrid closed loop technology in emergency surgery in a person with type 1 diabetes","authors":"H. Afridi, P. Olsen, N. Levy, K. Dhatariya","doi":"10.1002/anr3.70003","DOIUrl":"https://doi.org/10.1002/anr3.70003","url":null,"abstract":"<div>\u0000 \u0000 <p>Management of type 1 diabetes is constantly evolving. Hybrid closed loop technology is replacing multiple dose insulin and continuous subcutaneous insulin infusions as the preferred manner for managing type 1 diabetes in the community. Currently, there are no case reports or clinical guidelines to instruct practitioners on the safe peri-operative use of hybrid closed loop technology for patients requiring emergency surgery. In our case report we present the case of a 15-year-old male patient who required emergency surgery and wanted to continue the benefits of his hybrid closed loop technology in managing his diabetes peri-operatively. In addition, we discuss the strategies we used to overcome the issue of the continuous glucose monitor misreading paracetamol as glucose. Finally, we present the rationale for the guidance of safe peri-operative use of hybrid closed loop technology. This may allow other patients to benefit from continuation of hybrid closed loop technology during emergency surgery.</p>\u0000 </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}