{"title":"局部麻醉引起的急发型甲基血红蛋白血症1例","authors":"K. Zadeh, J. Bui, J. Lakshay, V. Vanam","doi":"10.1002/anr3.70013","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Methaemoglobinaemia is a rare but serious condition which can arise due to the administration of local anaesthetic agents. A 36-year-old woman with metastatic oesophageal adenocarcinoma experienced a rapid onset of methaemoglobinaemia following airway topicalisation with lidocaine and benzocaine sprays for bronchoscopy. The patient was treated with supplementary oxygen, non-invasive respiratory support, methylene blue and ascorbic acid. Early diagnosis and timely treatment of methaemoglobinaemia can result in rapid clinical improvement and prevent long-term complications.</p>\n </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"13 1","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of rapid onset methaemoglobinaemia associated with local anaesthetic use\",\"authors\":\"K. Zadeh, J. Bui, J. Lakshay, V. Vanam\",\"doi\":\"10.1002/anr3.70013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p>Methaemoglobinaemia is a rare but serious condition which can arise due to the administration of local anaesthetic agents. A 36-year-old woman with metastatic oesophageal adenocarcinoma experienced a rapid onset of methaemoglobinaemia following airway topicalisation with lidocaine and benzocaine sprays for bronchoscopy. The patient was treated with supplementary oxygen, non-invasive respiratory support, methylene blue and ascorbic acid. Early diagnosis and timely treatment of methaemoglobinaemia can result in rapid clinical improvement and prevent long-term complications.</p>\\n </div>\",\"PeriodicalId\":72186,\"journal\":{\"name\":\"Anaesthesia reports\",\"volume\":\"13 1\",\"pages\":\"\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-05-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anaesthesia reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/anr3.70013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/anr3.70013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
A case of rapid onset methaemoglobinaemia associated with local anaesthetic use
Methaemoglobinaemia is a rare but serious condition which can arise due to the administration of local anaesthetic agents. A 36-year-old woman with metastatic oesophageal adenocarcinoma experienced a rapid onset of methaemoglobinaemia following airway topicalisation with lidocaine and benzocaine sprays for bronchoscopy. The patient was treated with supplementary oxygen, non-invasive respiratory support, methylene blue and ascorbic acid. Early diagnosis and timely treatment of methaemoglobinaemia can result in rapid clinical improvement and prevent long-term complications.