Total intravenous anaesthesia with remimazolam in a patient with progressive supranuclear palsy

Abstract

Progressive supranuclear palsy is a neurodegenerative disease of unknown aetiology; few reports address its anaesthetic management. Remimazolam, a recently approved short-acting benzodiazepine, was used in combination with remifentanil for total intravenous anaesthesia during open cholecystectomy in a patient with progressive supranuclear palsy. Due to its cardiovascular stable profile and rapid reversibility with flumazenil, remimazolam may serve as a viable option for general anaesthesia in patients with this condition.