{"title":"Vitamin D and hypertension in the elderly; closer to implementation!","authors":"M. Chakhtoura, S. Alam","doi":"10.1016/j.ahjo.2025.100570","DOIUrl":"10.1016/j.ahjo.2025.100570","url":null,"abstract":"","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100570"},"PeriodicalIF":1.3,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustained mechanical aspiration thrombectomy for acute coronary syndrome with large thrombus burden: The Aspiration, Vasodilators, Imaging, and Stenting (AVIS) protocol","authors":"Tanuj Bhatia , Aditya Kapoor , Vishal Rastogi , Rajneesh Kapoor , Nakul Sinha , Rishi Sethi , Kunal Mahajan , Richa Sharma , Roopali Khanna , Sai Devvrat , Vanshaj Sharma","doi":"10.1016/j.ahjo.2025.100569","DOIUrl":"10.1016/j.ahjo.2025.100569","url":null,"abstract":"<div><h3>Study objective</h3><div>To evaluate the effectiveness and safety of sustained mechanical aspiration thrombectomy in acute coronary syndrome (ACS) patients with a large thrombus burden (LTB).</div></div><div><h3>Design</h3><div>This is a prospective observational study.</div></div><div><h3>Setting</h3><div>A Tertiary Healthcare Center in North India.</div></div><div><h3>Participants</h3><div>ACS patients with LTB recommended for percutaneous coronary intervention (PCI).</div></div><div><h3>Intervention</h3><div>Upfront sustained mechanical aspiration thrombectomy with The Indigo™ system CAT™ RX (Penumbra Inc., Alameda, CA) before primary PCI.</div></div><div><h3>Main outcome</h3><div>Primary outcomes included improvement in thrombolysis in myocardial infarction (TIMI) flow, TIMI thrombus grade, and myocardial blush grade (MBG). Clinical outcomes (death, recurrent MI, stroke) and improvement in LV function were recorded at baseline, 1 month and 6 months.</div></div><div><h3>Results</h3><div>Among 105 patients (median age 55 years, 82.9 % male), most had grade 5 thrombus (84.8 %), MBG grade 0 (84.8 %), and TIMI grade 0 flow (82.9 %) at baseline. After the procedure, significant improvements were observed in TIMI flow, TIMI thrombus grade, and MBG (<em>p</em> < 0.001). Three deaths were reported within the first 30 days, none of which were device related. There was a significant increase in the mean left ventricular ejection fraction from baseline to six month follow up (38.37 % vs. 44.63; <em>p</em> < 0.001).</div></div><div><h3>Conclusion</h3><div>Sustained mechanical aspiration thrombectomy effectively removed clots and aided in optimal myocardial perfusion in ACS patients with LTB. This study also proposes the utilization of the Aspiration, Vasodilators, Imaging, Stenting (AVIS) protocol to improve procedural success.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100569"},"PeriodicalIF":1.3,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicole Charbel , Karl Aramouni , Sam Sater , Firas Kreidieh
{"title":"Diagnosis, clinical management, and emerging strategies for coronary artery disease in patients with cancer","authors":"Nicole Charbel , Karl Aramouni , Sam Sater , Firas Kreidieh","doi":"10.1016/j.ahjo.2025.100568","DOIUrl":"10.1016/j.ahjo.2025.100568","url":null,"abstract":"<div><div>The intersection of cancer and coronary artery disease (CAD) presents complex clinical challenges requiring a multidisciplinary approach. Building on the first part of this review, which addressed epidemiology, shared risk factors, and pathophysiological mechanisms, this second part focuses on the diagnosis, screening, and management of CAD in patients with cancer, as well as management of cancer in CAD patients. Early identification of CAD remains challenging due to overlapping symptoms; thus, cardiovascular imaging modalities such as echocardiography, coronary computed tomography angiography, and cardiac magnetic resonance imaging, alongside cardiac biomarkers, are essential for accurate detection and risk stratification.</div><div>Screening strategies emphasize baseline cardiovascular risk evaluation and long-term surveillance, particularly for cancer survivors exposed to cardiotoxic therapies. Management of CAD in this population requires individualized pharmacologic and interventional strategies, balancing thrombotic, bleeding, and oncologic risks. The use of percutaneous coronary intervention and coronary artery bypass grafting (CABG) must be tailored to patient-specific cancer prognosis and cardiovascular status.</div><div>Moreover, several cancer therapies, including ERBB-2-targeted agents, angiogenesis inhibitors, and immune checkpoint inhibitors, are associated with cardiovascular toxicities, necessitating vigilant monitoring and timely interventions. Emerging fields such as anti-inflammatory therapy, clonal hematopoiesis of indeterminate potential integration, and artificial intelligence–based risk prediction offer promising strategies for improving outcomes. This second part of the review highlights the importance of a multidisciplinary cardio-oncology approach to optimize care for patients facing the dual burden of cancer and CAD.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100568"},"PeriodicalIF":1.3,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Playford , Tom Phillips , Enayet Chowdhury , Bryan Wai , Daneh Turner , Leighton Kearney
{"title":"Improved coronary artery interpretability without heart rate control for Coronary CT Angiography (CCTA) performed on a dedicated cardiac CT scanner using a second-generation motion correction algorithm","authors":"David Playford , Tom Phillips , Enayet Chowdhury , Bryan Wai , Daneh Turner , Leighton Kearney","doi":"10.1016/j.ahjo.2025.100566","DOIUrl":"10.1016/j.ahjo.2025.100566","url":null,"abstract":"","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100566"},"PeriodicalIF":1.3,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federico Viganego , Mark K. Meiselbach , Michael G. Fradley , Samer S. Najjar
{"title":"Changes in health insurance status and mortality in patients with acute heart failure","authors":"Federico Viganego , Mark K. Meiselbach , Michael G. Fradley , Samer S. Najjar","doi":"10.1016/j.ahjo.2025.100567","DOIUrl":"10.1016/j.ahjo.2025.100567","url":null,"abstract":"<div><h3>Introduction</h3><div>Health insurance changes (HIC) can lead to coverage gaps, alter the continuity of care, potentially affecting clinical outcomes; Heart Failure (HF) is a leading contributor to hospital readmissions in the U.S. We analyzed the relationship between HIC, readmission costs and mortality in patients with HF after a recent hospitalization.</div></div><div><h3>Methods</h3><div>We used data from the 2019 National Readmission Database to analyze 30-day re-admission incidence, costs and mortality in hospitalized HF patients in relation to HIC.</div></div><div><h3>Results</h3><div>Among 569,714 acute HF admissions, 4.2 % of patients (<em>n</em> = 4811) experienced HIC within 30 days; HIC were associated with younger age, more comorbidities, and Medicaid coverage. HIC were associated with higher readmission mortality, longer hospitalizations and increased hospital costs.</div></div><div><h3>Conclusion</h3><div>HIC in high-risk HF patients are associated with worse clinical outcomes and higher cost burden, highlighting the need for efforts aimed at preserving continuity of coverage in this population.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100567"},"PeriodicalIF":1.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144338221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasser M. Sammour, Budhaditya Bose, Chloe Kharsa, Sherif F. Nagueh, Neal S. Kleiman, Waqas Qureshi, Nadeen Faza, Joe Aoun, Sadeer Al-kindi, William A. Zoghbi, Sachin S. Goel, Khurram Nasir, Stephen H. Little
{"title":"Leveraging institutional echocardiographic registry to assess clinical profiles and outcomes in tricuspid regurgitation","authors":"Yasser M. Sammour, Budhaditya Bose, Chloe Kharsa, Sherif F. Nagueh, Neal S. Kleiman, Waqas Qureshi, Nadeen Faza, Joe Aoun, Sadeer Al-kindi, William A. Zoghbi, Sachin S. Goel, Khurram Nasir, Stephen H. Little","doi":"10.1016/j.ahjo.2025.100565","DOIUrl":"10.1016/j.ahjo.2025.100565","url":null,"abstract":"<div><div>Tricuspid regurgitation (TR) is a common valvular heart disease that is associated with increased morbidity and mortality. We utilized our large institutional echocardiographic registry, integrated with the electronic medical record-based health system registry to identify patients with varying degrees of TR, and to assess its association with long-term outcomes. Patients were categorized by TR severity as none, mild, moderate, or severe. A total of 88,511 unique individuals were included (44.7 % no reported TR, 49.0 % mild, 4.8 % moderate, and 1.5 % severe). Greater TR severity was associated with advanced age, female sex, and Black race, alongside higher prevalence of baseline comorbidities. Patients with moderate or severe TR exhibited worse congestion biomarkers, creatinine, liver enzymes, and reduced platelet counts. Echocardiographically, moderate or severe TR correlated with lower tricuspid annular plane systolic excursion, left ventricular ejection fraction, as well as larger biatrial and left ventricular volumes. There was a significant association between increasing TR severity and all-cause mortality at 3 years from the index echocardiogram compared with no TR (Moderate TR: AdjHR 1.76; 95 % CI 1.63–1.89; Severe TR: AdjHR 2.40; 95 % CI 2.16–2.66), and similarly for hospitalization (Moderate TR: AdjHR 1.14; 95 % CI 1.08–1.20; Severe TR: AdjHR 1.25; 95 % CI 1.15–1.36). In this large cross-sectional analysis, we highlight how institutional echocardiographic registries can be leveraged to identify the burden of TR, including its significant association with higher mortality and healthcare utilization. These findings emphasize the need for heightened clinical attention and potential intervention in patients with significant TR as tricuspid valve therapies evolve.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100565"},"PeriodicalIF":1.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah de Loizaga , McCall Miller , Barbie Giambra , LeCario Benashley , Billie Bones , Samantha Buonfiglio , Gwendena Lee Gatewood , Amanda Paxson , Teresa Pestian , Rachel Sarnacki , Rhiannon Walker , Dawnafe Whitesinger , Andrea Beaton , Lisa M. Vaughn
{"title":"Insights from one American Indian tribe about heart health","authors":"Sarah de Loizaga , McCall Miller , Barbie Giambra , LeCario Benashley , Billie Bones , Samantha Buonfiglio , Gwendena Lee Gatewood , Amanda Paxson , Teresa Pestian , Rachel Sarnacki , Rhiannon Walker , Dawnafe Whitesinger , Andrea Beaton , Lisa M. Vaughn","doi":"10.1016/j.ahjo.2025.100564","DOIUrl":"10.1016/j.ahjo.2025.100564","url":null,"abstract":"<div><h3>Background</h3><div>American Indians are impacted by significant health disparities compared to the general US population, with cardiovascular disease as a leading cause of death. Additionally, many American Indian populations face significant barriers to accessing specialty cardiac care. For one American Indian Tribe in Eastern Arizona, barriers to care include long distances to travel for echocardiography or cardiology consultation and delays in diagnosis. The purpose of this study was to gain insight into tribal perspectives of heart health and priorities in the design of a hearthealth program.</div></div><div><h3>Methods</h3><div>We used qualitative semi-structured interviews to examine Tribal experiences and perspectives surrounding heart health and health in general on Tribal lands. The Community Research Leadership Board assisted with developing the interview guide, recruitment, and data collection.</div></div><div><h3>Results</h3><div>A total of 19 interviews were completed. We used thematic analysis and identified five primary themes: 1) Awareness leads to understanding and acceptance; 2) Systemic barriers impede heart-health care; 3) Community engagement supports a sustainable heart-health program; 4) Heart-health initiatives can be influenced by personal perspectives; and 5) Expanded resources enable engagement.</div></div><div><h3>Conclusion</h3><div>Improvement in heart-health care and management is urgently needed for American Indian peoples who are disproportionately impacted by poor heart outcomes. Our findings suggest that a heart-health initiative for this Tribe needs to raise community awareness, address individual and systemic barriers, and leverage community strengths. These findings will directly inform planned persona development and community-based design workshops as we work toward a co-developed, impactful, and sustainable heart-health program.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100564"},"PeriodicalIF":1.3,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kun Huang , Feng Wen , Jingyi Li , Wenhao Niu , Hui Chen , Shilei Wan , Fupeng Yang , Yihong Chen , Chun Liang
{"title":"Early diagnosis of acute myocardial infarction via hub genes identified by integrated weighted gene co-expression network analysis","authors":"Kun Huang , Feng Wen , Jingyi Li , Wenhao Niu , Hui Chen , Shilei Wan , Fupeng Yang , Yihong Chen , Chun Liang","doi":"10.1016/j.ahjo.2025.100554","DOIUrl":"10.1016/j.ahjo.2025.100554","url":null,"abstract":"<div><h3>Background</h3><div>Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide. Circulating endothelial cells (CECs) have been reported to be involved with the early stages of AMI. The specific objective of our study was to discover early diagnostic markers of CECs in circulation using bioinformatics analysis.</div></div><div><h3>Methods</h3><div>Raw microarray data of the GSE66360 dataset were acquired from the Gene Expression Omnibus (GEO) database. The R software was used to filtrate differentially expressed genes (DEGs) from the discovery cohort of GSE66360 (<em>n</em> = 43). A weighted gene co-expression network analysis (WGCNA) was performed to explore the key modules connected with AMI. Next, main roles of the pathological states in AMI were analyzed using GO and KEGG and PPI networks. Diagnostic biomarkers were selected and identified using three machine learning algorithms. Additionally, the expression and diagnostic efficiency of hub genes were verified in the validation cohort (<em>n</em> = 56).</div></div><div><h3>Results</h3><div>366 DEGs were identified (20 upregulated and 306 downregulated). A total of 276 intersecting genes were markedly associated with AMI in the pink and turquoise modules. Based on multiple machine learning algorithms and independent validation, six genes including LILRA1, CCL20, IL1R2, TYROBP, CXCL16 and NFKBIA were identified as hub genes and showed satisfactory diagnostic efficiency both in the discovery cohort and validation cohort.</div></div><div><h3>Conclusion</h3><div>Our data provides evidence supporting a list of six hub genes to be trapped in the pathophysiology of AMI and proposes them as candidate biomarkers for the early diagnosis of AMI.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100554"},"PeriodicalIF":1.3,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helen S. Anwar , Magdy Algowhary , Mohamed Aboel-Kassem F. Abdelmegid , Hatem A. Helmy , J.M. Montero-Cabezas , Frank Van Der Kley
{"title":"Impact of aortic valve calcification volume on left ventricular systolic function in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation","authors":"Helen S. Anwar , Magdy Algowhary , Mohamed Aboel-Kassem F. Abdelmegid , Hatem A. Helmy , J.M. Montero-Cabezas , Frank Van Der Kley","doi":"10.1016/j.ahjo.2025.100562","DOIUrl":"10.1016/j.ahjo.2025.100562","url":null,"abstract":"<div><h3>Background</h3><div>Aortic valve calcification (AVC) has been linked to negative cardiac outcomes in patients with aortic stenosis (AS). Given the limited understanding of its specific contributions, we aimed to investigate the interaction between AVC and the left ventricular (LV) systolic function in patients with severe AS and LV systolic dysfunction who underwent transcatheter aortic valve implantation (TAVI).</div></div><div><h3>Materials and methods</h3><div>An observational study of 75 patients with severe AS and LV ejection fraction (EF) ≤ 50 % who underwent TAVI. AVC volume was determined by ECG-gated contrast-enhanced multidetector computed tomography (MDCT) using specific software (3Mensio Structural Heart version 10.4, Pie Medical Imaging, Maastricht, the Netherlands). Patients were categorized into two groups based on LV systolic function recovery 30 days after TAVI defined by ≥10 % absolute increase in LVEF compared to baseline.</div></div><div><h3>Results</h3><div>AVC volume showed a statistically significant negative correlation with the baseline LVEF (<em>r</em> = −0.33, <em>P</em> = 0.008) and a statistically significant positive correlation with the percentage of change in LVEF as compared to the baseline (<em>r</em> = 0.38, <em>P</em> = 0.001). In the logistic regression for post-TAVI LV systolic function recovery, AVC volume was associated with an increased likelihood of LV systolic function recovery.</div></div><div><h3>Conclusion</h3><div>AVC volume has a paradoxical association with LV systolic function. Patients with a higher AVC volume had a more depressed baseline LV systolic function and a greater likelihood of LV systolic function recovery after TAVI.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"56 ","pages":"Article 100562"},"PeriodicalIF":1.3,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144213506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riccardo Fenici , Marco Picerni , Peter Fenici , Donatella Brisinda
{"title":"Non-invasive mapping of ventricular action potential waveforms reconstructed from clinical unshielded magnetocardiography. Potential diagnostic application and current limitations","authors":"Riccardo Fenici , Marco Picerni , Peter Fenici , Donatella Brisinda","doi":"10.1016/j.ahjo.2025.100561","DOIUrl":"10.1016/j.ahjo.2025.100561","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the feasibility and limitations of reconstructing ventricular action potential waveforms using non-invasive, unshielded magnetocardiographic mapping (uMCG), highlighting differences between healthy individuals and patients, even at the current level of precision.</div></div><div><h3>Methods</h3><div>Clinical uMCG was performed using a 36-channel DC-SQUID system. The mathematical reconstruction method developed by Kandori et al. was applied to derive reconstructed ventricular action potential waveforms (rVAPw) from uMCG data in 10 healthy volunteers and 12 patients with various cardiac abnormalities. In four cases, simultaneous recordings of uMCG and right ventricular monophasic action potentials (RVMAP) were obtained using an amagnetic catheter technique.</div></div><div><h3>Results</h3><div>Reconstruction of rVAPw from uMCG signals was feasible in all subjects. Waveforms derived from 90-s averaged uMCG signals were comparable to those obtained with 300-s averages. The rVAPw closely matched the simultaneously recorded RVMAP waveforms. Compared to healthy individuals, patients showed a significant prolongation of rVAPw phase-0 (p < 0.01) and a trend toward increased total duration (p = 0.06), demonstrating the method's sensitivity to electrophysiological abnormalities.</div></div><div><h3>Conclusions</h3><div>While incomplete rVAPw at some MCG mapping sites reflects the current spatial resolution limitations of the uMCG array, the close alignment between rVAPw and RVMAP recordings suggests that 90-s uMCG acquisitions may suffice for reliable, non-invasive imaging of ventricular action potentials in clinical practice. These findings support further development of MCG technology as a medical device uniquely suited to bridge experimental and clinical applications by enabling non-invasive rVAPw mapping in patients. Future improvements in sensor technology, mathematical modelling, and multimodal imaging may allow for near-cellular spatial resolution.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"55 ","pages":"Article 100561"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144204253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}