American heart journal plus : cardiology research and practice最新文献

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Assessing athletes beyond routine screening: Incorporating essential factors to optimize cardiovascular health and performance 对运动员进行常规筛查以外的评估:纳入优化心血管健康和表现的基本因素
American heart journal plus : cardiology research and practice Pub Date : 2024-06-07 DOI: 10.1016/j.ahjo.2024.100413
Deen L. Garba , Alan P. Jacobsen , Roger S. Blumenthal , Matthew W. Martinez , Chiadi E. Ndumele , Alexis M. Coslick , Lili A. Barouch
{"title":"Assessing athletes beyond routine screening: Incorporating essential factors to optimize cardiovascular health and performance","authors":"Deen L. Garba ,&nbsp;Alan P. Jacobsen ,&nbsp;Roger S. Blumenthal ,&nbsp;Matthew W. Martinez ,&nbsp;Chiadi E. Ndumele ,&nbsp;Alexis M. Coslick ,&nbsp;Lili A. Barouch","doi":"10.1016/j.ahjo.2024.100413","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100413","url":null,"abstract":"<div><p>The American Heart Association (AHA) has devised Life's Essential 8, a set of eight evidence-based health behaviors that play a crucial role in optimizing cardiovascular health and overall well-being. In addition to Life's Essential 8, enhanced screening for Cardiovascular-Kidney-Metabolic (CKM) Syndrome risk factors into routine athlete screening also provides a more comprehensive approach for ensuring athlete safety and long-term health. Incorporating Life's Essential 8 and CKM Syndrome metrics into athlete health evaluations will improve the sports performance of athletes and help optimize their long-term health.</p></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"44 ","pages":"Article 100413"},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000569/pdfft?md5=1645a3fcbb99340b3ae2188388ef5b76&pid=1-s2.0-S2666602224000569-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141289990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endogenous androgens, coronary atheroma and remodeling in women with suspected ischemic heart disease: A report from the Women's Ischemia Syndrome Evaluation (WISE) study 疑似缺血性心脏病女性的内源性雄激素、冠状动脉粥样斑块和重塑:妇女缺血综合征评估(WISE)研究报告
American heart journal plus : cardiology research and practice Pub Date : 2024-05-31 DOI: 10.1016/j.ahjo.2024.100411
Sachini Ranasinghe , Ankur Jain , Yasmeen Taha , Eileen Handberg , B. Delia Johnson , Vera Bittner , George Sopko , Carl J. Pepine , R. David Anderson , C. Noel Bairey Merz
{"title":"Endogenous androgens, coronary atheroma and remodeling in women with suspected ischemic heart disease: A report from the Women's Ischemia Syndrome Evaluation (WISE) study","authors":"Sachini Ranasinghe ,&nbsp;Ankur Jain ,&nbsp;Yasmeen Taha ,&nbsp;Eileen Handberg ,&nbsp;B. Delia Johnson ,&nbsp;Vera Bittner ,&nbsp;George Sopko ,&nbsp;Carl J. Pepine ,&nbsp;R. David Anderson ,&nbsp;C. Noel Bairey Merz","doi":"10.1016/j.ahjo.2024.100411","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100411","url":null,"abstract":"<div><h3>Background</h3><p>Women have smaller coronary size than men independent of body surface area. Female to male heart transplantation demonstrates coronary lumen enlargement.</p></div><div><h3>Purpose</h3><p>To investigate relationships between endogenous androgens and coronary luminal size in women with suspected ischemic heart disease (IHD).</p></div><div><h3>Methods</h3><p>We analyzed 69 women with available androgen levels.</p></div><div><h3>Results</h3><p>Group mean age was 54 ± 10 years with 64 % post-menopausal. Lumen cross-sectional area (CSA) and external elastic membrane (EEM) CSA positively correlated with free testosterone (FT) (<em>r</em> = 0.29, <em>p</em> = 0.049; r = 0.29, <em>p</em> = 0.01), respectively, and negatively correlated with SHBG (<em>r</em> = −0.26, <em>p</em> = 0.03; <em>r</em> = −0.29, <em>p</em> = 0.02), respectively. Atheroma CSA positively correlated with FT (<em>r</em> = 0.24. <em>p</em> = 0.05). These correlations became non-significant after adjusting for waist circumference.</p></div><div><h3>Conclusions</h3><p>In women with suspected ischemic heart disease, endogenous androgens, coronary atheroma and luminal size are related, and may be moderated by waist circumference.</p></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100411"},"PeriodicalIF":0.0,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000545/pdfft?md5=19c5de1f9ce70c15ae3a15c09d405da7&pid=1-s2.0-S2666602224000545-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of magnetocardiography for myocarditis assessment in a testosterone-substituted female-to-male individual 应用磁心动图评估一名睾酮替代的女变男患者的心肌炎情况
American heart journal plus : cardiology research and practice Pub Date : 2024-05-31 DOI: 10.1016/j.ahjo.2024.100412
Phillip Suwalski , Finn Wilke , DeLisa Fairweather , Ulf Landmesser , Bettina Heidecker
{"title":"Application of magnetocardiography for myocarditis assessment in a testosterone-substituted female-to-male individual","authors":"Phillip Suwalski ,&nbsp;Finn Wilke ,&nbsp;DeLisa Fairweather ,&nbsp;Ulf Landmesser ,&nbsp;Bettina Heidecker","doi":"10.1016/j.ahjo.2024.100412","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100412","url":null,"abstract":"<div><h3>Background</h3><p>The diagnosis of myocarditis remains challenging due to its diverse clinical manifestations. We recently demonstrated the ability of magnetocardiography (MCG) to screen for myocarditis and applied it successfully to detect myocarditis in this case study of a female-to-male (FtM) patient who had undergone sexual reassignment surgery. This case highlights two significant points: first, sex differences in myocarditis may be promoted by higher levels of testosterone, and second, the ability of MCG to diagnose myocarditis.</p></div><div><h3>Case presentation</h3><p>We report on a 38-year-old FtM patient who was hospitalized for chest pain following testosterone therapy. The patient received testosterone every 2 weeks for 6 months following his FtM surgery. Two days after the last administration of testosterone, he developed chest pain. Electrocardiography identified non-significant ST elevations in V3–6, II and aVF and echocardiography revealed reduced left ventricular ejection fraction and apical hypokinesia. High-sensitivity troponin-T (539 ng/L to 676 ng/L) and creatine kinase elevation (592 U/L) were elevated. Coronary CT angiography ruled out coronary artery disease. Cardiac magnetic resonance imaging confirmed suspected myocarditis.</p><p>Additionally, we used MCG to detect abnormalities in the electromagnetic field. A pathologic vector (0.179) supported the diagnosis of myocarditis in this patient. During therapy with ibuprofen the vector improved to 0.067 after 3 weeks accompanied by symptom improvement.</p></div><div><h3>Conclusion</h3><p>Testosterone treatment may have promoted myocarditis in a FtM individual. Additional MCG assessment was consistent with a diagnosis of myocarditis and highlights the promising potential of this method to facilitate diagnostic screening for cardiomyopathy in the future.</p></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100412"},"PeriodicalIF":0.0,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000557/pdfft?md5=534c2aea6adfa817049f907f0e2b9a62&pid=1-s2.0-S2666602224000557-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ShopTalk – Barbers as partners in health promotion: Reviewing social determinants of health, revisiting cardiology pioneers, and moving forward ShopTalk - 理发师是促进健康的伙伴:回顾健康的社会决定因素,重温心脏病学先驱,向前迈进
American heart journal plus : cardiology research and practice Pub Date : 2024-05-29 DOI: 10.1016/j.ahjo.2024.100410
Aqeel Khanani , Daniel Haight
{"title":"ShopTalk – Barbers as partners in health promotion: Reviewing social determinants of health, revisiting cardiology pioneers, and moving forward","authors":"Aqeel Khanani ,&nbsp;Daniel Haight","doi":"10.1016/j.ahjo.2024.100410","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100410","url":null,"abstract":"<div><p>Social Determinants of Health (SDOH) like education, economic stability, social context, neighborhood environment, and healthcare access are increasingly recognized as major drivers of persistent health disparities, particularly among minority populations. Over the past year, studies have demonstrated and quantified the impact that certain SDOH have on uncontrolled blood pressure in Black and Hispanic adults compared to white adults. This underscores the need to view chronic diseases through a SDOH lens and implement multilevel interventions targeting these underlying social factors to achieve health equity.</p><p>The ShopTalk initiative, based in Lakeland, Florida, represents a promising community-based approach to addressing SDOH and health disparities. It conducts health outreach in barbershops and hair salons - trusted community hubs where meaningful dialogues occur. Key components include providing health education materials, offering screenings, and facilitating physician connections, all at no cost. By leveraging these culturally-relevant spaces, ShopTalk simultaneously targets multiple SDOH domains like health literacy, economic barriers, neighborhood familiarity, and healthcare engagement.</p><p>This builds upon the pioneering work of leaders like Dr. Elijah Saunders and Dr.</p><p>Ronald Victor, who previously engaged social hubs to successfully raise hypertension awareness among underserved populations. As highlighted by Healthy People 2030's emphasis on SDOH, widespread implementation of such culturally-tailored community outreach shows potential for finally reducing longstanding disparities. Specific outcome measures are planned to optimize ShopTalk, with the goal of extracting generalizable insights to guide similar initiatives nationwide.</p></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100410"},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000533/pdfft?md5=542a32e723ab18c7596bc6b4c39cd3aa&pid=1-s2.0-S2666602224000533-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, predictors, and in-hospital outcomes of ST-elevation myocardial infarction among young adults without traditional cardiovascular risk factors in the United States 美国无传统心血管风险因素的年轻成年人中 ST 段抬高型心肌梗死的发病率、预测因素和住院治疗结果
American heart journal plus : cardiology research and practice Pub Date : 2024-05-28 DOI: 10.1016/j.ahjo.2024.100408
Garba Rimamskep Shamaki , Israel Safiriyu , Akanimo Antia , Waddah K. Abd El-Radi , Chiwoneso Beverley Tinago , Onyedika Ilonze
{"title":"Prevalence, predictors, and in-hospital outcomes of ST-elevation myocardial infarction among young adults without traditional cardiovascular risk factors in the United States","authors":"Garba Rimamskep Shamaki ,&nbsp;Israel Safiriyu ,&nbsp;Akanimo Antia ,&nbsp;Waddah K. Abd El-Radi ,&nbsp;Chiwoneso Beverley Tinago ,&nbsp;Onyedika Ilonze","doi":"10.1016/j.ahjo.2024.100408","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100408","url":null,"abstract":"<div><h3>Background</h3><p>Standard Modifiable Cardiovascular Risk Factors (SMuRF) such as hypertension, diabetes mellitus, hypercholesterolemia, and smoking have long been established in the etiology of atherosclerotic disease. Studies suggest that patients without any of these risk factors (SMuRF-less) who present with ST-elevation myocardial infarction have worse outcomes.</p></div><div><h3>Methods</h3><p>The National Inpatient Sample databases (2016 to 2020) was queried to identify STEMI admissions as a principal diagnosis using ICD 10 codes. The study population aged 18 to 45 years were divided into cohorts of SMuRF and SMuRF-less based on the presence of ≥1 risk factor (hypertension, diabetes mellitus, hyperlipidemia, and smoking), and in-hospital outcomes were compared.</p></div><div><h3>Results</h3><p>41,990 patients were identified as the final study population. 38,495 patients were identified as SMuRF, and 3495 patients were SMuRF-less. Compared to SMuRF patients, SMuRF-less patients are more likely to be females (23.2 % vs. 21.2 %), have congestive heart failure (16.6 % vs. 13.7 %, <em>p</em> &lt; 0.01) but less likely to have obesity (13.7 % vs 28.0 %, <em>p</em> &lt; 0.01) In evaluating outcomes, SMuRF-less patients had higher adjusted in-hospital mortality (aOR 2.6, CI 1.5–4.2, <em>p</em> &lt; 0.01), Cardiogenic shock (aOR 1.8, CI 1.3–2.5, p &lt; 0.01), acute kidney injury (aOR 1.4, CI 1.0–1.9, <em>p</em> = 0.02), and Extramembrane Corporeal Oxygenation (aOR 4.1, CI 1.1–15.1, <em>p</em> = 0.03). Fluid and electrolyte abnormalities was an independent predictor of mortality among SMuRF-less patients (aOR 3.82, CI 1.3–11.2, <em>p</em> &lt; 0.01).</p></div><div><h3>Conclusion</h3><p>Young patients who present with STEMI and have no traditional cardiovascular risk factors have worse in-hospital outcomes. Further research is needed to evaluate the impact of non-traditional risk factors on acute myocardial infarction.</p></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100408"},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266660222400051X/pdfft?md5=779abcc2da21ae74c3c0b7309ab29d22&pid=1-s2.0-S266660222400051X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Open arteries and pandemic viruses: Tackling today's clinical conundrums for the future of cardiology 开放的动脉和流行的病毒:应对当今临床难题,开创心脏病学的未来
American heart journal plus : cardiology research and practice Pub Date : 2024-05-28 DOI: 10.1016/j.ahjo.2024.100409
Peter V. Johnston
{"title":"Open arteries and pandemic viruses: Tackling today's clinical conundrums for the future of cardiology","authors":"Peter V. Johnston","doi":"10.1016/j.ahjo.2024.100409","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100409","url":null,"abstract":"","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100409"},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000521/pdfft?md5=6b664e8dae58f5f7545c3b80fef72484&pid=1-s2.0-S2666602224000521-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
More than just teeth: How oral health can affect the heart 不仅仅是牙齿口腔健康如何影响心脏
American heart journal plus : cardiology research and practice Pub Date : 2024-05-24 DOI: 10.1016/j.ahjo.2024.100407
Steven Hopkins , Saivaroon Gajagowni , Yusuf Qadeer , Zhen Wang , Salim S. Virani , Jukka H. Meurman , Roman Leischik , Carl J. Lavie , Markus Strauss , Chayakrit Krittanawong
{"title":"More than just teeth: How oral health can affect the heart","authors":"Steven Hopkins ,&nbsp;Saivaroon Gajagowni ,&nbsp;Yusuf Qadeer ,&nbsp;Zhen Wang ,&nbsp;Salim S. Virani ,&nbsp;Jukka H. Meurman ,&nbsp;Roman Leischik ,&nbsp;Carl J. Lavie ,&nbsp;Markus Strauss ,&nbsp;Chayakrit Krittanawong","doi":"10.1016/j.ahjo.2024.100407","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100407","url":null,"abstract":"<div><p>Epidemiological evidence has revealed a potential relationship between periodontal disease and cardiovascular disease (CVD). Consensus regarding a link between these pathologies remains elusive, however, largely secondary to the considerable overlap between risk factors and comorbidities common to both disease processes. This review article aims to update the evidence for an association by summarizing the evidence for causality between periodontitis and comorbidities linked to CVD, including endocarditis, hypertension (HTN), atrial fibrillation (AF), coronary artery disease (CAD), diabetes mellitus (DM) and hyperlipidemia (HLD). This article additionally discusses the role for periodontal therapy to improved management of the comorbidities, with the larger goal of examining the value of periodontal therapy on reduction of CVD risk. In doing so, we endeavor to further the understanding of the commonality between periodontitis, and CVD.</p></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100407"},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000508/pdfft?md5=fbbf458584dbda576d6ea6cd20386534&pid=1-s2.0-S2666602224000508-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiovascular implications of anti-angiogenic therapeutic agents in cancer patients 抗血管生成治疗剂对癌症患者心血管的影响
American heart journal plus : cardiology research and practice Pub Date : 2024-05-23 DOI: 10.1016/j.ahjo.2024.100406
Layal Al Mahmasani , Ghassan K. Abou-Alfa
{"title":"Cardiovascular implications of anti-angiogenic therapeutic agents in cancer patients","authors":"Layal Al Mahmasani ,&nbsp;Ghassan K. Abou-Alfa","doi":"10.1016/j.ahjo.2024.100406","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100406","url":null,"abstract":"","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100406"},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000491/pdfft?md5=17a5c1ce8a8d1c71cb4d092ab3571222&pid=1-s2.0-S2666602224000491-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Racial differences in baroreflex function: Implications for the cardiovascular conundrum 气压反射功能的种族差异:心血管难题的含义
American heart journal plus : cardiology research and practice Pub Date : 2024-05-20 DOI: 10.1016/j.ahjo.2024.100403
DeWayne P. Williams , Cameron R. Wiley , Julia Birenbaum , Grace M. Fishback , Lassiter F. Speller , Julian Koenig , Marc Jarczok , Gaston Kapuku , Gustavo A. Reyes del Paso , LaBarron K. Hill , Julian F. Thayer
{"title":"Racial differences in baroreflex function: Implications for the cardiovascular conundrum","authors":"DeWayne P. Williams ,&nbsp;Cameron R. Wiley ,&nbsp;Julia Birenbaum ,&nbsp;Grace M. Fishback ,&nbsp;Lassiter F. Speller ,&nbsp;Julian Koenig ,&nbsp;Marc Jarczok ,&nbsp;Gaston Kapuku ,&nbsp;Gustavo A. Reyes del Paso ,&nbsp;LaBarron K. Hill ,&nbsp;Julian F. Thayer","doi":"10.1016/j.ahjo.2024.100403","DOIUrl":"https://doi.org/10.1016/j.ahjo.2024.100403","url":null,"abstract":"<div><h3>Study objective</h3><p>African Americans (AAs) show early signs of vascular dysfunction paired with elevated blood pressure (BP) and total peripheral resistance (TPR), which is thought to underlie their increased rates of cardiovascular health complications relative to European Americans (EAs). AAs paradoxically have higher cardiac vagal tone, indexed by heart rate variability (HRV), which is cardio-protective. This paradox has been termed the <em>Cardiovascular Conundrum</em>. The physiological mechanism underlying this phenomenon is not well understood. We examined race differences in baroreflex function, which might be an important mechanism underlying the <em>Cardiovascular Conundrum</em>.</p></div><div><h3>Design</h3><p>Participants completed a 5-minute baseline period where resting cardiac metrics were assessed.</p></div><div><h3>Setting</h3><p>Laboratory.</p></div><div><h3>Participants</h3><p>130 college-aged individuals (54 women, 57 AAs).</p></div><div><h3>Main outcome measures</h3><p>Baroreflex function was indexed as baroreflex sensitivity (BRS; the magnitude of changes in cardiovascular activity in accordance with BP changes) and effectiveness (BEI; the ratio of BP changes that elicit changes in cardiovascular activity) in the cardiac, vascular, and myocardial limbs.</p></div><div><h3>Results and conclusions</h3><p>Results showed AAs to have higher HRV and cardiac BRS in comparison to EAs, suggesting the baroreflex is more sensitive to correcting the heart period for changes in BP among AAs compared to EAs. However, AAs showed lower vascular BEI relative to EAs, suggesting less effective control of TPR. In sum, lower BEI in the vascular branch might be an important mechanism underlying the <em>Cardiovascular Conundrum</em> (i.e., higher HRV and BP) and by extension, health disparities in cardiovascular diseases between AAs and EAs.</p></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"43 ","pages":"Article 100403"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666602224000466/pdfft?md5=0f280561cfee73c434699c24ad591cfb&pid=1-s2.0-S2666602224000466-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141242688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender, racial and ethnic disparities in acute coronary syndromes with coronary in-stent restenosis 伴有冠状动脉支架内再狭窄的急性冠状动脉综合征的性别、种族和民族差异
American heart journal plus : cardiology research and practice Pub Date : 2024-05-20 DOI: 10.1016/j.ahjo.2024.100405
Shivaraj Patil , Chaitanya Rojulpote , William Frick , Abhijit Bhattaru , Karanjit Sandhu , Aditya Bakhshi , Anum Shahzad , Gregg Pressman , Antonio Chamoun , Div Verma , Chien-Jung Lin
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