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Correction of Iatrogenic Facial Asymmetry Caused by Botulinum Toxin Using Contralateral Injection: A Case Report. 对侧注射纠正医源性肉毒杆菌毒素致面部不对称1例。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-20 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag051
Muhammad Rayyan Bilal, Rana Hassan Javaid, Afsheen Bilal
{"title":"Correction of Iatrogenic Facial Asymmetry Caused by Botulinum Toxin Using Contralateral Injection: A Case Report.","authors":"Muhammad Rayyan Bilal, Rana Hassan Javaid, Afsheen Bilal","doi":"10.1093/asjof/ojag051","DOIUrl":"https://doi.org/10.1093/asjof/ojag051","url":null,"abstract":"<p><p>Facial symmetry is a key determinant of aesthetic harmony and psychosocial well-being. Iatrogenic asymmetry is a recognized complication of botulinum toxin injections and may cause both functional and emotional distress. Contralateral botulinum toxin adjustment is an accepted corrective strategy, but few case reports have documented its use for toxin-induced asymmetry with photographic evidence. A 44-year-old woman developed facial asymmetry after cosmetic botulinum toxin injections. She presented with upward deviation of the left oral commissure and midface both at rest and during speech, causing psychosocial discomfort. Dynamic assessment showed relative overactivity of the left facial muscles compared with the weakened right side. Targeted contralateral injections of botulinum toxin type A were delivered into the left zygomaticus minor, depressor anguli oris, and mentalis muscles (14 units). At the 2-week follow-up, the patient showed substantial restoration of facial balance with improved commissure position and symmetry. Posttreatment photographs confirmed correction. No adverse events were observed. Contralateral botulinum toxin injection is a possible minimally invasive method for correcting toxin-induced asymmetry. <b>Level of Evidence: 5 (Therapeutic)</b>.</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag051"},"PeriodicalIF":1.9,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13070422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why the "Y" Becomes a "Trans-Y": Validation of the "Number Y" for Implant Height Prediction in Gender-Affirming Breast Augmentation Using Anatomical Implants. 为什么“Y”变成了“Trans-Y”:“数字Y”在性别确认隆胸手术中植入物高度预测的验证。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-19 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag049
Sascha Wellenbrock, Laetitia S Chiarella, Isabel Kiehlmann, Tobias Hirsch, Charalampos Varnava, Maximilian Kueckelhaus, Marie-Luise Aitzetmüller-Klietz, Matthias Aitzetmüller-Klietz, Ulrich M Rieger
{"title":"Why the \"<i>Y</i>\" Becomes a \"Trans-<i>Y</i>\": Validation of the \"Number <i>Y</i>\" for Implant Height Prediction in Gender-Affirming Breast Augmentation Using Anatomical Implants.","authors":"Sascha Wellenbrock, Laetitia S Chiarella, Isabel Kiehlmann, Tobias Hirsch, Charalampos Varnava, Maximilian Kueckelhaus, Marie-Luise Aitzetmüller-Klietz, Matthias Aitzetmüller-Klietz, Ulrich M Rieger","doi":"10.1093/asjof/ojag049","DOIUrl":"https://doi.org/10.1093/asjof/ojag049","url":null,"abstract":"<p><p>Breast augmentation is the most frequently performed gender-affirming surgery (GAS) for transfeminine individuals. Because of anatomical differences between transfeminine and cisgender women, implant selection requires tailored planning. The \"Number <i>Y</i>\" is an established method for implant height selection in cisgender patients. Since its adoption for transfeminine patients at our institution in 2016, its reliability in this population has not been validated. The aim of this study was to validate the Number <i>Y</i> in transfeminine patients, identify anatomical factors influencing implant height prediction, and propose an adjusted \"Number trans-<i>Y</i>\" to improve surgical planning. This retrospective study included 21 transfeminine patients undergoing breast augmentation as part of GAS. Preoperative implant height predictions using the Number <i>Y</i> were compared with actual intraoperative implant choices. Implant shapes were categorized as vertical-elliptical, circular, or horizontal-elliptical. Patient and implant characteristics were analyzed for concordance. The mean patient age was 39.62 years, BMI of 25.42, and the mean Number <i>Y</i> of 4.31, higher than reported in cisgender cohorts. Implant height prediction was accurate in 16 patients (76.19%). Discordant cases (23.81%) had significantly smaller thoracic perimeters (9 cm difference, <i>P</i> = .01) and lower Number <i>Y</i> (3.96 ± 0.11 vs 4.42 ± 0.28; <i>P</i> < .001). Most concordant cases received low-height implants, whereas discordant cases were predicted to require middle-height implants but ultimately received low-height implants. The Number <i>Y</i> has limited predictive accuracy in transfeminine patients because of distinct thoracic anatomy and higher <i>Y</i> factors. An adjusted Number trans-<i>Y</i> is proposed to optimize implant selection and surgical outcomes in this population. <b>Level of Evidence: 4 (Therapeutic)</b>.</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag049"},"PeriodicalIF":1.9,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decoding the Digital Discourse: A Thematic and Sentiment Analysis of Reddit Posts on Eyelid Surgery. 解读数字话语:关于眼睑手术的Reddit帖子的主题和情感分析。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-18 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag050
Henry Bair, Haley Evans, Lara Cheslow, Charlotte L Marous
{"title":"Decoding the Digital Discourse: A Thematic and Sentiment Analysis of Reddit Posts on Eyelid Surgery.","authors":"Henry Bair, Haley Evans, Lara Cheslow, Charlotte L Marous","doi":"10.1093/asjof/ojag050","DOIUrl":"10.1093/asjof/ojag050","url":null,"abstract":"<p><strong>Background: </strong>Eyelid surgery is among the most performed aesthetic and functional procedures, yet existing patient-reported outcome measures may miss unprompted concerns voiced on social media.</p><p><strong>Objectives: </strong>The aim of this study was to characterize emotions, language use, and patient priorities in Reddit discussions about eyelid surgery.</p><p><strong>Methods: </strong>The authors performed a cross-sectional mixed-methods analysis of English-language posts and top-level comments from 8 subreddits (May 12, 2024 to May 12, 2025). A transformer-based model and the National Research Council Emotion Lexicon were used to assign sentiment polarity and discrete emotions and to quantify postcomment concordance. Sociolinguistic features (lexical richness, readability, and medical terminology density) were computed for all entries. A random sample of 500 entries underwent inductive thematic analysis.</p><p><strong>Results: </strong>The authors analyzed 1579 posts and 3576 top-level comments. Posts demonstrated mixed sentiment polarity (39.0% positive, 32.2% negative, and 28.8% neutral), whereas comments were more often positive (55.8%) than negative (24.1%) or neutral (20.1%). Across postcomment pairs (1 pair per comment), 64.5% were discordant, most commonly negative post → positive comment. Fear and sadness predominated in posts, whereas trust and anticipation were more common in comments. Medical terminology appeared frequently yet was often imprecise. Thematic analysis yielded 9 themes, including preoperative anxiety, dissatisfaction despite acceptable results, distress over mild asymmetry, and social-media-driven surgeon selection.</p><p><strong>Conclusions: </strong>Reddit discourse reveals clinically literate but diagnostically uncertain patients who judge success by culturally inflected, photo-salient aesthetics and rely on peer reassurance. Early vocabulary alignment and explicit counseling on asymmetry and variability may improve expectation setting and generate testable hypotheses for counseling strategies.</p><p><strong>Level of evidence 5 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag050"},"PeriodicalIF":1.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Professional Outcomes Following The Aesthetic Society-Endorsed Aesthetic Surgery Fellowships: A Single Program Fellowship Review and National Survey. 美学学会认可的美容外科奖学金的专业成果:单一项目奖学金审查和全国调查。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-18 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag048
Bhavana Thota, Carolyn Kim, Shikhar Tomur, Jennifer Barillas, William P Adams, Jeffrey M Kenkel
{"title":"Professional Outcomes Following The Aesthetic Society-Endorsed Aesthetic Surgery Fellowships: A Single Program Fellowship Review and National Survey.","authors":"Bhavana Thota, Carolyn Kim, Shikhar Tomur, Jennifer Barillas, William P Adams, Jeffrey M Kenkel","doi":"10.1093/asjof/ojag048","DOIUrl":"10.1093/asjof/ojag048","url":null,"abstract":"<p><strong>Background: </strong>The number of The Aesthetic Society-endorsed aesthetic surgery fellowship (ASEAF) programs has grown in recent years as more plastic surgery residents pursue advanced training in aesthetic procedures following residency.</p><p><strong>Objectives: </strong>The aim of this study was to describe the structure and case volume of one long-established ASEAF program and summarize practice patterns and self-reported experiences of nationwide ASEAF graduates (from the US programs) across 6 academic years.</p><p><strong>Methods: </strong>A retrospective review of case logs from 6 aesthetic surgery fellows at a single institution from the 2018 to 2023 academic years was conducted. Additionally, an anonymous 5-question survey was distributed to 125 ASEAF graduates nationwide from the same time period.</p><p><strong>Results: </strong>Fellows at the study institution completed a total of 3113 aesthetic cases with an average distribution of 80.5% surgical and 19.5% nonsurgical procedures. Breast augmentation was the most common surgical procedure early in the study period, whereas rhinoplasty predominated in later years. Neuromodulator injections were the most common nonsurgical procedure performed. Among 64 survey respondents (51.2% response rate) representing 24 endorsed fellowship programs nationwide, most reported practicing in group private practice settings (<i>n</i> = 44, 68.8%). Facial aesthetic surgery represented the largest portion of respondents' current practice (28%).</p><p><strong>Conclusions: </strong>This study provides descriptive insights into the structure and case volume of 1 ASEAF program and reports trends in practice settings and procedural focus among ASEAF graduates nationwide. These findings offer a snapshot of aesthetic fellowship training and early career patterns but do not assess patient outcomes or compare endorsed fellowships with other training pathways. Future research with larger cohorts, longer follow-ups, and objective measures is needed to better understand the long-term professional impact of aesthetic fellowship training.</p><p><strong>Level of evidence 5 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag048"},"PeriodicalIF":1.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peptide Hydrogel Enhances Adipocyte Viability and Reduces Inflammatory Response in Fat Grafting: A Preclinical Study. 肽水凝胶增强脂肪细胞活力,减少脂肪移植中的炎症反应:一项临床前研究。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-12 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag045
Itay Wiser, Noa Harduf, Guy Tomer, Gregory Perelman, Alexandra Tsitrina, Hanna Rapaport, Guy Gersh, Inna Solodeev, Orel Govrin, Bar Kamhine, Yoav Barnea, Benjamin Meilik, Yaron Rapaport, Nadav Orr
{"title":"Peptide Hydrogel Enhances Adipocyte Viability and Reduces Inflammatory Response in Fat Grafting: A Preclinical Study.","authors":"Itay Wiser, Noa Harduf, Guy Tomer, Gregory Perelman, Alexandra Tsitrina, Hanna Rapaport, Guy Gersh, Inna Solodeev, Orel Govrin, Bar Kamhine, Yoav Barnea, Benjamin Meilik, Yaron Rapaport, Nadav Orr","doi":"10.1093/asjof/ojag045","DOIUrl":"https://doi.org/10.1093/asjof/ojag045","url":null,"abstract":"<p><strong>Background: </strong>Fat grafting is gaining traction in regenerative and aesthetic medicine because of ease of adipose tissue harvesting and potential applications in autologous soft tissue reconstructions. A key challenge remains the limited viability of lipoaspirate-derived adipocytes following the procedures of harvesting, processing, and implantation, which leads to suboptimal outcomes in graft survival.</p><p><strong>Objectives: </strong>The aim of this study was to evaluate whether a hydrogel composed of the amphiphilic and anionic β-sheet peptide Pro-Asp-(Phe-Asp)5-Pro (PFD) enhances fat graft outcomes by improving adipocyte viability, reducing inflammatory response, and facilitating tissue integration compared with conventional fat grafting.</p><p><strong>Methods: </strong>PFD-lipoaspirate mixtures were characterized in vitro, and a lead mixture was tested in porcine models used for initial safety and efficacy assessment of subcutaneous implantation at 1 and 3 months after treatment. A single animal was used for each time point, with multiple treatment sites in each animal and a minimum of 3 sites for each of the treatment and control formulations. Histological and immunohistochemical analyses were performed.</p><p><strong>Results: </strong>PFD hydrogel exhibited superior injectability with smaller extrusion force than hyaluronic acid. The hydrogel could be readily mixed with lipoaspirate to form cohesive, uniform compositions that demonstrated a smoother and more consistent injection force pattern, compared with lipoaspirate only. Hydrogel-lipoaspirate formulations significantly enhanced cell viability compared with lipoaspirate. Within the lipoaspirate, the hydrogel degraded enzymatically. In vivo studies showed the hydrogel-lipoaspirate seamless integration with the surrounding adipose tissue with a 7-fold reduction in inflammatory zones compared with lipoaspirate-only treatment. Macrophage profiling indicated a transition toward predominantly M2 polarization between 1 and 3 months, supported by neovascularization and near-complete resorption by 3 months.</p><p><strong>Conclusions: </strong>PFD hydrogel-lipoaspirate mixture showed favorable outcomes in this preclinical model through improved adipocyte survival, reduced inflammatory response, and seamless tissue integration. These preliminary findings suggest potential utility in fat grafting applications, although clinical validation remains necessary.</p><p><strong>Level of evidence 5 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag045"},"PeriodicalIF":1.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness and Safety of Belotero Intense ± Lidocaine for the Correction of Nasolabial Folds, Marionette Lines, and Lip Volume Enhancement: A Randomized Post-Market Clinical Follow-Up Study. Belotero强效±利多卡因矫正鼻唇褶皱、木偶纹和唇容的有效性和安全性:一项随机上市后临床随访研究。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-11 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag031
Peter Arne Gerber, Rodrigo da Mota, Gerd Gauglitz, Daniela Greiner-Krüger, Michael Sebastian, Welf Prager, Maria Kravtsov, Christian Carreon, YingJu Tseng, Sonja Sattler
{"title":"Effectiveness and Safety of Belotero Intense ± Lidocaine for the Correction of Nasolabial Folds, Marionette Lines, and Lip Volume Enhancement: A Randomized Post-Market Clinical Follow-Up Study.","authors":"Peter Arne Gerber, Rodrigo da Mota, Gerd Gauglitz, Daniela Greiner-Krüger, Michael Sebastian, Welf Prager, Maria Kravtsov, Christian Carreon, YingJu Tseng, Sonja Sattler","doi":"10.1093/asjof/ojag031","DOIUrl":"10.1093/asjof/ojag031","url":null,"abstract":"<p><strong>Background: </strong>Although hyaluronic acid-based dermal fillers are widely used, real-world effectiveness and safety data remain limited.</p><p><strong>Objectives: </strong>To confirm the effectiveness and safety of Belotero Intense and Belotero Intense Lidocaine (cohesive polydensified matrix hyaluronic acid fillers) in a real-world setting.</p><p><strong>Methods: </strong>In this multicenter, randomized, rater-blind, uncontrolled, post-market clinical study, 98 participants from 7 sites were randomized 1:1 to Belotero Intense (<i>n</i> = 50) or Belotero Intense Lidocaine (<i>n</i> = 48) (Anteis S.A., Plan-les-Ouates, Switzerland, a company of the Merz Aesthetics group), administered to 2-3 facial areas (nasolabial folds, marionette lines, and upper/lower lips including lip border), with optional touch-up at Week 4. Primary effectiveness endpoints were responder rate (defined as ≥1 point improvement compared with baseline on both sides of the treated area or both lips) at 12 weeks after last injection on the Merz Aesthetics Scales.</p><p><strong>Results: </strong>The responder rate was 85.5% for nasolabial folds (95% confidence interval [CI] 78.4, 92.6; <i>P</i> < .0001), 83.5% for marionette lines (95% CI 75.5, 91.4; <i>P</i> < .0001), and 57.4% for lip volume (95% CI 46.2, 68.7; <i>P</i> = .0967). <i>Post hoc</i> analyses using a revised definition of response for the lips (≥1 point improvement in at least one lip) demonstrated a clinical meaningful improvement (85.1% responder rate; 95% CI 77.0, 93.2). The overall incidence of treatment-related treatment-emergent adverse events was 24.5% and was comparable across the 3 treatment areas.</p><p><strong>Conclusions: </strong>Under real-world conditions, this study demonstrated that Belotero Intense and Belotero Intense Lidocaine were effective and well tolerated in the correction of nasolabial folds, marionette lines and lip volume.</p><p><strong>Level of evidence 3 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag031"},"PeriodicalIF":1.9,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12997526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infections in Implant-Based Breast Reconstruction: A Systematic Review of Risk Factors, Prevention, and Salvage Strategies. 假体乳房再造术中的感染:危险因素、预防和挽救策略的系统回顾。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-06 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag044
Elisa Maria Ragaini, Camilla Ferrari, Roberta Comunian, Mattia Federico Cavallero, Stefano Vaccari, Davide Fiore Bavaro, Francesco Klinger, Valeriano Vinci, Riccardo Di Giuli
{"title":"Infections in Implant-Based Breast Reconstruction: A Systematic Review of Risk Factors, Prevention, and Salvage Strategies.","authors":"Elisa Maria Ragaini, Camilla Ferrari, Roberta Comunian, Mattia Federico Cavallero, Stefano Vaccari, Davide Fiore Bavaro, Francesco Klinger, Valeriano Vinci, Riccardo Di Giuli","doi":"10.1093/asjof/ojag044","DOIUrl":"https://doi.org/10.1093/asjof/ojag044","url":null,"abstract":"<p><p>Implant-based breast reconstruction (IBR) is the most commonly adopted technique following mastectomy because of its relative simplicity and shorter recovery time. However, infection remains one of its most frequent and challenging complications, potentially leading to delayed adjuvant therapy, increased healthcare costs, and implant loss. This systematic review provides an updated and structured appraisal of current evidence on infections in IBR, focusing on the following key outcomes: risk factors associated with postoperative infections; preventive strategies, including systemic and local prophylaxis; microbiological patterns and pathogen distribution; clinical outcomes across different reconstructive stages; and management and salvage approaches, including criteria for implant preservation vs explantation. A systematic search was performed in PubMed, Scopus, Embase, and Google Scholar following Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 for studies published between January 2010 and May 2024. Studies were included if they reported original human data on infections after IBR. Twelve studies were analyzed for infection rates, microbiology, prophylaxis, and management. Infection rates ranged from 4.5% to 19.4%. <i>Staphylococcus aureus</i> and coagulase-negative staphylococci were most common. Main risk factors included obesity, diabetes, radiotherapy, smoking, and acellular dermal matrices. Preventive measures varied widely. Salvage was attempted in up to 80% of cases, with success rates of 42.9% to 90.9%. Biofilm and culture-negative infections were major challenges. Infections in implant-based reconstruction remain multifactorial and clinically demanding, with heterogeneous prevention and management strategies and limited consensus. Standardized definitions, improved microbiology, and validated salvage pathways are needed to enhance outcomes. <b>Level of Evidence</b>: 4 (Therapeutic).</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag044"},"PeriodicalIF":1.9,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13042246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recombinant Platelet-Derived Growth Factor BB vs Autologous Nanofat to Enhance Recovery After CO2 Laser and Microneedling: A Split-Face, Randomized Controlled Trial. 重组血小板衍生生长因子BB vs自体纳米脂肪提高CO2激光和微针后的恢复:一项裂面随机对照试验。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-06 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag033
R Brannon Claytor, Patricia M Fuentes, Grace Tolan, Kay Durairaj, Robert Quigley, Samuel E Lynch
{"title":"Recombinant Platelet-Derived Growth Factor BB vs Autologous Nanofat to Enhance Recovery After CO<sub>2</sub> Laser and Microneedling: A Split-Face, Randomized Controlled Trial.","authors":"R Brannon Claytor, Patricia M Fuentes, Grace Tolan, Kay Durairaj, Robert Quigley, Samuel E Lynch","doi":"10.1093/asjof/ojag033","DOIUrl":"10.1093/asjof/ojag033","url":null,"abstract":"<p><p>Nanofat has been used as a \"rescue\" modality to support healing after CO<sub>2</sub> laser resurfacing with microneedling. Because demand grows for less invasive facial rejuvenation options, recombinant platelet-derived growth factor (rhPDGF-BB) has emerged as a popular adjunct to enhance postresurfacing recovery. The aim of this study was to compare autologous Nanofat to rhPDGF-BB as rescue treatments for pain and skin recovery following combined thermal and mechanical injury for improvement of facial rhytids. Five patients underwent full-face CO<sub>2</sub> laser treatment followed by microneedling. Each patient received split-face randomization: one side was treated with Nanofat and the contralateral side with rhPDGF-BB (300 µg/mL). Patients were blinded to allocation. Standardized 3 mm biopsies were obtained at baseline and at postprocedure Day 4, 1 month, 3 months, and 6 months and evaluated by a blinded board-certified histopathologist. Outcomes included practitioner- and patient-reported Perioral Rhytid Severity Rating Scale (PR-SRS), Global Aesthetic Improvement Scale (GAIS), and patient satisfaction. Both treatments improved patient/practitioner PR-SRS and GAIS beginning on Day 4 and continuing through 6 months. There were no significant differences between treatment groups (<i>P</i> > .05). Patients reported high satisfaction with both treatment groups. Overall, histopathology assessments demonstrated that both Nanofat and rhPDGF-BB supported normal wound healing and produced comparable tissue remodeling over time. Differences between treatments were subtle and confined to the early inflammatory interval, with Nanofat showing a consistently milder inflammatory response. This is the first human histologic split-face study of rhPDGF-BB in facial rejuvenation. This preliminary study found that either Nanofat or rhPDGF-BB treatment following full-face CO<sub>2</sub> laser treatment and microneedling resulted in improved clinical and histologic outcomes. Nanofat showed milder early inflammatory changes, but both treatments produced normal wound healing and robust extracellular matrix formation and comparable tissue remodeling by 1, 3, and 6 months. <b>Level of Evidence:</b> 2 (Therapeutic).</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag033"},"PeriodicalIF":1.9,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13015916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brazilian Breast Sculpting: A Standardized Approach to Mastopexy Without Implants. 巴西乳房雕刻:一种无植入物乳房切除术的标准化方法。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-02 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag040
Jeimeson Costa, Jediael Magalhães Paiva, Guilherme Bastida, Ana Luiza Chagas Maneira, Ana Elisa Kadri, Caroline Wippich
{"title":"Brazilian Breast Sculpting: A Standardized Approach to Mastopexy Without Implants.","authors":"Jeimeson Costa, Jediael Magalhães Paiva, Guilherme Bastida, Ana Luiza Chagas Maneira, Ana Elisa Kadri, Caroline Wippich","doi":"10.1093/asjof/ojag040","DOIUrl":"https://doi.org/10.1093/asjof/ojag040","url":null,"abstract":"<p><p>The authors evaluated the feasibility, safety, and patient-reported outcomes of a standardized autologous protocol (\"Brazilian Breast Sculpting\") that integrates liposuction, Liacyr flap creation, intramuscular and subcutaneous fat grafting, a muscular sling, and an internal bra. In this prospective case series, 38 patients (mean age 44 years; BMI ≤28) underwent the 6-step protocol between January 2023 and November 2024 and completed at least 12 months of follow-up. Patient-reported outcomes were assessed at 12 months using the Brazilian Portuguese version of the BREAST-Q reduction/mastopexy module. All patients completed the standardized protocol. Postoperative morbidity was low; wound dehiscence occurred in 5 patients (13.2%) and suture extrusion in 7 (18.4%), with all cases managed conservatively. At 12 months, mean BREAST-Q scores (0-100) suggested high satisfaction, particularly for satisfaction with breasts and physical well-being (chest). These preliminary findings suggest that Brazilian Breast Sculpting is a feasible autologous approach to mastopexy without implants with favorable patient-reported outcomes and an acceptable safety profile. <b>Level of Evidence:</b> 4 (Therapeutic).</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag040"},"PeriodicalIF":1.9,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partial Submandibular Gland Resection in Deep Neck Surgery: An Assessment of Safety Using the LigaSure Exact Dissector. 深颈部手术部分颌下腺切除术:使用LigaSure精确解剖器的安全性评估。
IF 1.9
Aesthetic surgery journal. Open forum Pub Date : 2026-03-02 eCollection Date: 2026-01-01 DOI: 10.1093/asjof/ojag041
Paul N Afrooz, Natalie B Carter
{"title":"Partial Submandibular Gland Resection in Deep Neck Surgery: An Assessment of Safety Using the LigaSure Exact Dissector.","authors":"Paul N Afrooz, Natalie B Carter","doi":"10.1093/asjof/ojag041","DOIUrl":"https://doi.org/10.1093/asjof/ojag041","url":null,"abstract":"<p><strong>Background: </strong>Optimal cervicomandibular contour often necessitates management of subplatysmal structures, including the submandibular glands (SMGs). Partial SMG excision may enhance neck definition but remains controversial because of concerns regarding bleeding and other potential complications. The LigaSure Exact Dissector (Medtronic, Minneapolis, MN) is a bipolar vessel-sealing device that has been adopted by some surgeons for SMG management during aesthetic neck surgery.</p><p><strong>Objectives: </strong>To evaluate the short-term safety and postoperative complication profile of partial SMG excision using the LigaSure Exact Dissector during aesthetic neck lift surgery.</p><p><strong>Methods: </strong>A retrospective observational case series was conducted of patients undergoing partial SMG excision as part of primary neck lift procedures between August 2023 and January 2025. All SMG excisions were performed using the LigaSure Exact Dissector. Patient demographics and postoperative complications were recorded. Outcomes were analyzed descriptively, with a minimum follow-up of 3 months (mean follow-up, 5 months).</p><p><strong>Results: </strong>Of 123 neck lift procedures, 80 patients (65%) underwent bilateral partial SMG excision. Mean age was 58.7 years (range, 34-73 years); 57 patients (71%) were female and 23 (29%) male, with a mean body mass index of 24.5. Complications included seroma in 3 patients (3.75%), minor hematoma in 1 patient (1.25%), and transient lower-lip weakness in 4 patients (5%), all resolving within 8 weeks. No permanent nerve injury, sialoma, infection, or xerostomia occurred.</p><p><strong>Conclusions: </strong>Partial SMG excision using the LigaSure Exact Dissector was associated with a low rate of short-term complications. These findings suggest the technique can be safely performed in appropriately selected patients undergoing aesthetic neck lift surgery. Further comparative studies are warranted.</p><p><strong>Level of evidence: </strong>4 (Therapeutic).</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag041"},"PeriodicalIF":1.9,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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