{"title":"A Prospective Study on Helium-Based Plasma Radiofrequency for Minimally Invasive Breast Lift Scarless Mastopexy.","authors":"Aris Sterodimas, Argyris Moutafis, Beatriz Nicaretta, Grigorios Champsas","doi":"10.1093/asjof/ojaf004","DOIUrl":"https://doi.org/10.1093/asjof/ojaf004","url":null,"abstract":"<p><strong>Background: </strong>Although mastopexy addresses breast ptosis, not all patients are willing or able to undergo surgery. Helium plasma radiofrequency (RF) is a minimally invasive alternative to traditional excisional breast lift surgery for mild-to-moderate breast ptosis.</p><p><strong>Objectives: </strong>To assess the efficacy and safety of helium plasma RF for minimally invasive mastopexy.</p><p><strong>Methods: </strong>In this single-center prospective study, 15 patients were treated with helium plasma RF. Before and after photographs were assessed by blinded review 180 days postprocedure. Morphometric analysis and evaluations using investigator- and patient-assessed Global Aesthetic Improvement Scales (I-GAIS and P-GAIS, respectively) were carried out on posttreatment Days 30, 90, and 180. On Day 180, patients completed a satisfaction questionnaire and the Breast-Q scale.</p><p><strong>Results: </strong>At Day 180, the independent photographic review success rate was 73% (11/15). There was improvement in suprasternal notch to nipple distance (-1.2 ± 0.7 cm), midclavicular line to nipple distance (-0.9 ± 0.7 cm), and vertical distance from the suprasternal notch to the lowest point on the base (-1.5 ± 1.0 cm). Morphometric measurement appeared to improve over time, as did improvements in P-GAIS and I-GAIS. All patients (15/15) reported less sagging, higher appearance of breasts on the chest, improved nipple placement, more youthful-appearing breasts, and improved confidence and quality of life on the Breast-Q. There were no adverse events or pain reported during the procedure or follow-ups.</p><p><strong>Conclusions: </strong>This study suggests that helium plasma RF is a well-tolerated and effective minimally invasive option for patients seeking an alternative to traditional breast lift surgery.</p><p><strong>Level of evidence 5 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf004"},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11997781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Retrospective Evaluation of the Safety of Combining Helium-Based Plasma Radiofrequency Technology With Ultrasound-Assisted Lipoabdominoplasty.","authors":"Paul Vanek","doi":"10.1093/asjof/ojae116","DOIUrl":"https://doi.org/10.1093/asjof/ojae116","url":null,"abstract":"<p><strong>Background: </strong>Helium plasma radiofrequency (RF; Renuvion; Apyx Medical, Clearwater, FL) is cleared for use in the coagulation/contraction of subcutaneous soft tissue, in body contouring, and to address loose skin in the neck and submental region. The device instantly heats target tissue to >85 °C, causing rapid protein coagulation within 0.04 s, resulting in tissue contraction. The use of multiple energy-based devices in lipoabdominoplasty is controversial.</p><p><strong>Objectives: </strong>To assess the safety of helium plasma RF as an adjunct to lipoabdominoplasty utilizing ultrasound-assisted liposuction (UAL; VASER, Solta Medical, Bothell, WA).</p><p><strong>Methods: </strong>In this retrospective, single-center study, medical records for patients who underwent UAL and abdominoplasty with or without helium-based plasma RF as an adjunct for subdermal coagulation between October 2017 and March 2023 were reviewed. Primary outcomes included significant and nonsignificant adverse events (AEs). Univariate and multivariate analyses were used to identify any risk factors for AEs.</p><p><strong>Results: </strong>A total of 40 patients treated with lipoabdominoplasty and helium plasma RF and 37 patients treated with lipoabdominoplasty alone were included in the analysis. Overall, no significant difference between groups was detected for the occurrence of significant AEs (<i>P</i> = .628).</p><p><strong>Conclusions: </strong>In this study, it is indicated that the helium plasma RF device may be a safe adjunct for UAL lipoabdominoplasty. When used for subdermal coagulation in the abdominal area, the device does not appear to increase the incidence of serious AEs or introduce risk to the flap.</p><p><strong>Level of evidence 3 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojae116"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11997769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jasmine A Panton, Bhavana Thota, Abby J Culver, Jeffrey M Kenkel
{"title":"Measuring Medical Student Scholarly Activity After a Structured Plastic Surgery Research Fellowship: A Bibliometric Analysis.","authors":"Jasmine A Panton, Bhavana Thota, Abby J Culver, Jeffrey M Kenkel","doi":"10.1093/asjof/ojaf012","DOIUrl":"10.1093/asjof/ojaf012","url":null,"abstract":"<p><strong>Background: </strong>Plastic surgery is consistently one of the most competitive medical specialties in the National Resident Matching Program match, with students often partaking in dedicated research fellowships to bolster their applications.</p><p><strong>Objectives: </strong>The purpose of this study was to quantify the academic productivity of medical students completing a structured plastic surgery research fellowship at a single academic center over a 7-year period.</p><p><strong>Methods: </strong>The bibliometric output of 26 medical student research fellows was analyzed. Eligible scholarly activities for analysis included peer-reviewed articles, books and book chapters, and video editorials published in the field of plastic surgery and indexed between July 1 of the fellowship and September 1, 2023. Cross-verified citation lists were generated for each author and <i>h</i>-index, publication number, number of citing articles, sum of times cited, author position, and journal or book title were recorded.</p><p><strong>Results: </strong>Twenty-four of 26 research fellows have published a total of 177 scholarly activities (93.22% articles) which have been cited in ∼322 articles. The mean publication per fellow is 6.69 and the mean <i>h-</i>index is 1.46. Analysis excluding the 2022-2023 cohort revealed a strong positive correlation between years since beginning research fellowship and both mean <i>h</i>-index (<i>r</i> = 0.84, <i>P</i> < .001) and mean number of publications per year (<i>r</i> = 0.81, <i>P</i> < .001).</p><p><strong>Conclusions: </strong>Structured research fellowships can serve as a springboard for medical students to increase research output and engage meaningfully with academia. The authors of this study suggest that publications in peer-reviewed journals continue to increase following participation in a structured plastic surgery research fellowship.</p><p><strong>Level of evidence 4 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf012"},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Partial Submandibular Gland Resection With Ultrasonic Dissector vs Electrocautery.","authors":"Hallie Buckner, Anil R Shah","doi":"10.1093/asjof/ojaf011","DOIUrl":"https://doi.org/10.1093/asjof/ojaf011","url":null,"abstract":"<p><strong>Background: </strong>The superficial aspect of the submandibular gland can be removed to improve the aesthetic appearance of the face and neck. This study describes a novel surgical technique to resect part of the submandibular gland during a deep neck or facelift.</p><p><strong>Objectives: </strong>Describe the technique to remove the superficial lobe of the submandibular gland using an ultrasonic dissector. Analyze the association between the uses of ultrasonic technology and reduced postoperative complications. Compare rates of postoperative complications between standard electrocautery and ultrasonic dissection.</p><p><strong>Methods: </strong>Experimental and control groups were established. A Sonicision ultrasonic dissector (Covidien, Dublin, Ireland) was used for resection in the experimental group, whereas electrocautery was used for resection in the control group. Postoperative outcomes of neuropraxia, hematoma, seroma, and sialocele formation were collected. Statistical analysis was performed using a Fisher's exact test in RStudio.</p><p><strong>Results: </strong>Control patients (<i>n</i> = 32) experienced 1 hematoma, 3 seromas, 3 sialoceles, and 3 neuropraxias. Experimental patients (<i>n</i> = 48) experienced 2 seromas with no hematomas, sialoceles, or neuropraxia. No association of statistical significance between reduced risk of complications and use of ultrasonic dissection was found.</p><p><strong>Conclusions: </strong>This novel technique has the potential to improve the safety and efficacy of partial submandibular gland resection. However, a follow-up study with a greater sample size and without confounding variables, such as intraoperative injection of Botulinum toxin, is necessary.</p><p><strong>Level of evidence 3: </strong>(Therapeutic).</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf011"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11997774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven Harris, Fabrizio Castellari, Madara Orlovska, Don Othoro, Greg Bran
{"title":"Instagram vs Reality: Assessment of the Representation of Lip Aesthetic Subtypes on Social Media Using the Lip Classification of Tubercles System.","authors":"Steven Harris, Fabrizio Castellari, Madara Orlovska, Don Othoro, Greg Bran","doi":"10.1093/asjof/ojaf010","DOIUrl":"10.1093/asjof/ojaf010","url":null,"abstract":"<p><strong>Background: </strong>Social media platforms, particularly Instagram appear to be influencing contemporary beauty standards, especially concerning lip enhancements. Understanding the prevalent lip types showcased can offer valuable insights into evolving aesthetic ideals to inform both patients and practitioners.</p><p><strong>Objectives: </strong>This study aims to analyze lip types associated with minimally invasive lip enhancements on Instagram (Meta, Menlo Park, CA) and compare these findings with classifications from a patient clinic using the Lip Classification of Tubercles system.</p><p><strong>Methods: </strong>A within-participants design was employed to examine 120 \"before and after\" images from 4 trending Instagram hashtags related to lip enhancements. Four expert examiners performed the classification, and interrater reliability was assessed. Data from a previous study involving patients from an aesthetic clinic (<i>n</i> = 214) were incorporated to compare the frequencies of lip types in the clinic and on Instagram.</p><p><strong>Results: </strong>The interrater reliability for lip classification on Instagram was very good (Fleiss' Kappa: pretreatment <i>k</i> = 0.817; posttreatment <i>k</i> = 0.837). The most common lip-type pretreatment was 1A, which dramatically shifted to Type 3A posttreatment. The comparison with the patient clinic revealed that although Type 1A was the most prevalent in both datasets, Instagram exhibited lower variability, with only 10 unique types identified pretreatment and a predominant Type 3A posttreatment.</p><p><strong>Conclusions: </strong>The representations of lip enhancements on Instagram reflect a narrower range of lip types compared with clinical findings, including a dramatic shift toward a Type 3A lip shape. This standardization of beauty ideal highlights the need for further exploration of social media's influence on lip enhancement preferences and the associated risks, as well as how these trends shape patient expectations in aesthetic practices.</p><p><strong>Level of evidence 4 diagnostic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf010"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Graeme E Glass, András Mérai, Szabolcs Molnár, Paul Clayton
{"title":"The Use of a Proprietary Near-Infrared Laser to Enhance Wound Healing: A Preliminary Preclinical and Clinical Study.","authors":"Graeme E Glass, András Mérai, Szabolcs Molnár, Paul Clayton","doi":"10.1093/asjof/ojaf009","DOIUrl":"10.1093/asjof/ojaf009","url":null,"abstract":"<p><strong>Background: </strong>Nonthermal light energy has been used to enhance wound healing. This is known as photobiomodulation. Although preclinical evidence is largely based on laser light, light-emitting diodes (LEDs) form the mainstay of clinical studies owing to the lack of available lasers for nonclinical use. However, it is speculated the 2 technologies exhibit dissimilar biological responses.</p><p><strong>Objectives: </strong>The influence of a new, commercially available near-infrared laser device on the gene expression profile of human skin relative to an equivalent, near-infrared LED device was evaluated. Additionally, the wound healing potential of the device was examined in practice.</p><p><strong>Methods: </strong>Defatted human skin was exposed to the laser (3), LED (3), or negative control (3) for 5 days. On Day 6, skin samples were biopsied for ribonucleic acid extraction and gene expression assays run for 107 genes of interest. Twenty patients with chronic wounds were randomized to receive standard wound care ± laser therapy 3 times weekly for 4 weeks, and wounds were analyzed for healing.</p><p><strong>Results: </strong>The laser altered expression of 45 genes. Highly up-regulated genes (>5-fold change) included those implicated in wound healing and antiaging, whereas highly down-regulated genes included those implicated in inflammation and extracellular matrix integrity. The LED device altered expression of only 1 gene relative to negative controls. The laser reduced mean wound area by 78% and healed 4 of 10 wounds completely. In contrast, 8 of 10 of those receiving standard care exhibited no change.</p><p><strong>Conclusions: </strong>A proprietary near-infrared laser exhibited superior ability to influence gene expression in healthy skin than an equivalent LED device and induced the healing of chronic wounds.</p><p><strong>Level of evidence 2 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf009"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Commentary on: The Role of Nasal Fat Preservation in Upper Lid Surgery and Assessment With the FACE-Q Questionnaire: Innovations in Upper Blepharoplasty.","authors":"","doi":"10.1093/asjof/ojaf007","DOIUrl":"https://doi.org/10.1093/asjof/ojaf007","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/asjof/ojae097.].</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf007"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paradoxical Adipose Hyperplasia of Submental Region After Cryolipolysis Treated With Deep-Plane Neck Lift: A Case Report.","authors":"Heather M Zimmerman, J Simon Ivey","doi":"10.1093/asjof/ojaf008","DOIUrl":"10.1093/asjof/ojaf008","url":null,"abstract":"<p><p>Cryolipolysis is a technique to reduce adipose tissue with localized cooling. Paradoxical adipose hyperplasia (PAH) is a known risk of this procedure and presents with a voluminous swelling in the treated region, generally occurring 2 to 4 months after. Most cases of PAH are noted in the umbilical region, and it has been infrequently noted in the submental region. The researchers of previous reports have noted liposuction or excision as proposed treatments. In this study, the authors report on a case of PAH after 2 sessions of cryolipolysis to the submental region, which was treated with deep-plane neck lift (DPNL) for total correction. Intraoperative removal of sub- and supraplatysmal fibrotic fat, glandular material, and muscle was utilized for optimal results. The patient had total correction of the deformity and maintained results at several months postoperatively. This case would have been poorly treated with liposuction because of the dense structural material and fibrotic subplatysmal fat noted intraoperatively. Patients undergoing cryolipolysis for adipose reduction of the submental region should be counseled on the risk of PAH, and DPNL should be evaluated further as the standard for correction of this condition.</p><p><strong>Level of evidence 5 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf008"},"PeriodicalIF":0.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11903390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippe Kestemont, Ferial Fanian, Philippe Garcia, Anne Grand-Vincent, Laurent Benadiba, Henry Delmar, Isaac Bodokh, Patrick Brun, Frédéric Braccini, Christophe Desouches, Jérôme Paris, Ismahane Guimiot, Catherine Salomon, Patrick Trévidic
{"title":"Long-term Efficacy and Safety of a Hyaluronic Acid-Based Dermal Filler With Tri-Hyal Technology to Enhance Lip Volume.","authors":"Philippe Kestemont, Ferial Fanian, Philippe Garcia, Anne Grand-Vincent, Laurent Benadiba, Henry Delmar, Isaac Bodokh, Patrick Brun, Frédéric Braccini, Christophe Desouches, Jérôme Paris, Ismahane Guimiot, Catherine Salomon, Patrick Trévidic","doi":"10.1093/asjof/ojae110","DOIUrl":"https://doi.org/10.1093/asjof/ojae110","url":null,"abstract":"<p><strong>Background: </strong>Interventions to enhance lip volume and shape are common aesthetic procedures to counter signs of aging.</p><p><strong>Objectives: </strong>This study aimed to assess the efficacy of Art Filler Lips (AFL), with or without retouching, at restoring lip shape and volume, tolerability, and persistence over 18 months.</p><p><strong>Methods: </strong>During this open-label study, AFL (≤2.0 mL) was injected into the upper, lower, and/or both red lips and borders at baseline (D0). Patients were evaluated at D21, when, if necessary, retouching was performed. Patients were evaluated at D42, D90, D180, D270, D360, D450, and D540. The primary assessment was based on evaluation at D21 using the Medicis Lip Fullness Scale (MLFS). Satisfactory volume restoration was defined as an improvement of ≥1 point vs D0. Secondary outcomes were adverse events (AEs), and investigator and patient satisfaction rates based on Global Aesthetic Improvement Scores.</p><p><strong>Results: </strong>Among 73 patients (97% females; 54.4 ± 10.5 years), 56% of lips were injected without any retouch. Mean MLFS scores either for upper and lower lips separately or together, significantly improved by D21 for the patients without retouching or D42 for those with (all <i>P</i> < .0001). At D21/42, 99% of upper lips, 94% of lower lips, and 96% of both lips showed satisfactory volume restoration. This proportion declined between D21/42 and D540. The most reported immediate AEs were swelling, sensitivity, and pain and were mild to moderate, lasting for <2 weeks.</p><p><strong>Conclusions: </strong>AFL is well tolerated and produces a sustained objective and subjective lip volume restoration and shape.</p><p><strong>Level of evidence 4 risk: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojae110"},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12041919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven F Weiner, Jessica A Hicks, Thu Nguyen, Matthew Meckfessel
{"title":"Split-Face Comparison of Two Hyaluronic Acid Fillers: Intersection of Rheology and Tissue Behavior in Midface Rejuvenation.","authors":"Steven F Weiner, Jessica A Hicks, Thu Nguyen, Matthew Meckfessel","doi":"10.1093/asjof/ojaf006","DOIUrl":"https://doi.org/10.1093/asjof/ojaf006","url":null,"abstract":"<p><strong>Background: </strong>Hyaluronic acid (HA) fillers are one of the most popular aesthetic treatments for midface volumization, achieving optimal aesthetic improvements. Given the variety of HA filler products available, it is important for injectors to understand how their rheological properties can influence behavior in tissues.</p><p><strong>Objectives: </strong>To evaluate and compare (1) product integration and dynamic support and (2) lifting capacity of 2 rheologically different HA fillers (HA Contour [HA<sub>CON</sub>] and HA Voluma [HA<sub>JVOL</sub>]) through ultrasound and clinical photography.</p><p><strong>Methods: </strong>Randomized, split-face study (<i>n</i> = 11) comparing 2 midface HA fillers over a 12-month period with initial injection along the zygomatic arch at Day 0 and optional touch-up at Month 1. Eligible patients were aged 22 to 65 years with midface volume loss and contour deficiency. Assessments included ultrasound (neutral and smiling), clinical photography with 3D volume change (lifting capacity) analyses, and adverse event reporting. Volume change was assessed at 2 regions: midface and infraorbital hollow (IOH).</p><p><strong>Results: </strong>With similar average total injection volumes, both fillers had comparable lifting capacity in the midface (HA<sub>CON</sub>: ≥2.07 mL and HA<sub>JVOL</sub>: ≥2.08 mL; <i>P</i> > .05) and IOH (HA<sub>CON</sub>: ≥0.45 mL and HA<sub>JVOL</sub>: ≥0.57 mL; <i>P</i> > .05) areas for up to 12 months. Ultrasound showed that HA<sub>CON</sub> integrated into the tissue, stretching and elongating during a smiling expression, whereas HA<sub>JVOL</sub> did not integrate as much, with aggregates consistent in size and shape during both neutral and smiling expressions through 12 months. No adverse events were reported during the study.</p><p><strong>Conclusions: </strong>HA<sub>CON</sub> demonstrated a similar duration of lifting capacity (volumization) as HA<sub>JVOL</sub> but had more distributed product integration and flexibility to support dynamic expressions through 12 months.</p><p><strong>Level of evidence 3 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"7 ","pages":"ojaf006"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11997782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}