{"title":"Functional structure in lymphoepithelial cooperation.","authors":"I Törö, I Oláh, Z Kittner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the help of electron microscopic investigations the morphological and functional connection of the epithelialial and lymphoid elements was examined in the lymphoepithelial organs (thymus, bursa of Fabricius, tonsils, Peyer's patches, gland of Harder). In all these organs special receptor cells were demonstrated, which may play a role in the uptake and transfer of the antigen. In the cytoplasm they all contain characteristic flattened vacuoles, with walls similar to the structure of the cell membrane. Formation of these bodies is identified with the striated bodies of micropinocytosis vermiformis and it was observed that the endocytosis start with a disintegration of the cell membrane which enters with the absorbed antigen in characteristic form into the cytoplasm of the epithel cell and induces the process of cellular immunity. Besides the function of lacrimal secretion the Harder's gland, as a lymphoepithelial organ is full of plasma cells, which constitutes the main lymphoid elements of this organ.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 4","pages":"375-91"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18475305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Forms and causes of human malformations.","authors":"W Lenz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18052805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis of skull fractures by autopsy and radiology.","authors":"E Ehler, D Ivánkievicz, G H Schumacher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fifteen human cadaver heads after fixation in formalin were studied. Half of them were exposed to force applied fronto-occipitally. In the remainder the force was applied roughly vertically from the parietal bone towards a line connecting the two internal acoustic pores. The loads were increased until a fracture had occurred. The analysis was based on both halves of each head. Total number of fractures detected by autopsy and radiology. Formula: (See Text). Those who remember that the conditions of X-rays of live subjects are substantially more complicated than those of a severed cadaver head will certainly be very cautious when examining X-ray material for signs of a fracture of the skull basis under clinical conditions. Our data are based on fifteen skulls. It must nevertheless be assumed that results obtained from a larger number of samples would not differ appreciably.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 3","pages":"291-6"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18456869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An epizootic of Akabane disease in bovines, ovines and caprines in Israel, 1969-70: epidemiological assessment.","authors":"S Shimshony","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"197-9"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17830785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Examination of normal and abnormal lip development in mouse embryos using in vivo and in vitro techniques.","authors":"J Langman, T W Sadler, D T Burk, J D Gaare","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"125-33"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18456908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The study of bone tissue with new argyrophilic techniques.","authors":"M Bély, F Gallyas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fractured and necrotic bones were examined by new silver impregnation techniques based on the catalytic activity of the bone. The new methods proved to be useful in differentiating between bone tissues of various ages and maturity and between living and necrotic bones.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 3","pages":"281-9"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17226502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of post-implantation embryo culture to problems in teratology.","authors":"D L Cockroft","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rat embryos explanted at 9 1/2 or 11 1/2 days of gestation and cultured in rotating bottles were subjected to a number of agents. Embryos explanted at 9 1/2 days (head-fold stage) and incubated for 48 h at 40.5 degrees C were retarded and abnormal and these effects were more severe in embryos cultured at 41 degrees C. Embryos exposed to 40 degrees over this period were superficially normal, but separate head and body protein determinations and careful measurement of the head dimensions showed them to be microcephalic. Addition of 12-15 mg/ml D-glucose to the culture medium of embryos grown in vitro over the same period also produces malformations. This teratogenic action of D-glucose is distinct from but exacerbated by its osmotic effect. Embryos explanted 12 h earlier (i.e. at 9 days of gestation) and cultured for 66 h were more sensitive to excess glucose--abnormalities were produced by 6-9 mg/ml exogenous D-glucose. Embryos explanted at 11 1/2 days of gestation and cultured for 18 h responded to both 10% CO and suboptimal oxygen levels with a reduction in growth rate and an increase in the ratio of lactate produced to glucose consumed, suggesting a shift to less efficient anaerobic energy metabolism.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"117-24"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18456907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introduction to symposium on epidemiology in teratology.","authors":"J A Weatherall","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"165-6"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18456909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathomorphology of acute lymphoblastic leukaemia in childhood: convolution of lymphoblast nuclei.","authors":"T Pap, I Retih, P Kajtár, G Kelényi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the period between 1960--1978 36 children dead with acute lymphoblastic leukaemia (ALL) were studied. Nine cases were found to be in pathological remission, i.e., without any leukaemia infiltrations (7 of these were seen in the last 5 years). The remaining 27 could be divided into two groups on the basis of nuclear structure: in 20 cases the lymphoblastic nuclei were round or oval and their convolution was pycnotic, \"highly convoluted\", or lobulated, in 7 the nuclei were round or oval and their convolution was slight. The survival was 10.8 months in the first and 3.6 months in the second group. Although the origin and the degree of differentiation of the cells of these two groups are not clearly known, it seems that the two types represent different stages of T-lymphoblast evolution.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 4","pages":"407-16"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17986853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The amphicrine (endo-exocrine) cells in the human gut, with a short reference to amphicrine neoplasias.","authors":"M Ratzenhofer, L Auböck","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the human gastrointestinal tract the amphicrine cells are described as a special form of endocrine cells. Depending on their behaviour under silver impregnation, they are divided into three subgroups: the mucoargentaffine, the mucoargyrophilic and the mucoargyrophobic cells. They were detected electron microscopically in 1969, but they were histologically verified and identified as mucus-excreting endocrine elements only in 1977. Since 1969 such cells have also been observed in normal and regenerating rat and mouse stomachs. Our own human material includes stomach (3 cases), appendix (12 cases), colon (1) and a series of amphicrine proliferations and tumours. Two cases of chronic gastritis and one chronic peptic ulcer with metaplastic and regenerating epithelium contained mucoargyrophilic cells with mucus below the nucleus in the atypical glands. The possibility of endocrine granules being sluiced out in the mucous grains is discussed. Of the appendices only two were normal (ages 6 and 7 years), 10 showed pathological changes: there were seven neurogenic appendicopathies (14-58 years), one lymphatic hyperplasia, and one hyperplasia of mucoargyrophobic cells with mucostasis. Mucoargentaffine cells far outnumbered the mucoargyrophilic and mucoargyrophobic cells. The mucus may have either an apical or basal location; in the latter case, paracrine secretion into the subepithelial lamina propria was seen. As neoplastic cells, the amphicrine cells form the rare amphicrine tumours (goblet-cell and muco-adenoid carcinoids) of the appendix and colon. They are also found in mucinous cystadenomas of the ovary [26], in the enteral type of a nasal carcinoma [27,28], and in a 5-HT-carcinoid of the ovary [15]. They are therefore to be regarded as a differentiation disorder of the endocrine cells under the pathological conditions of appendicopathy, hyperplasia, metaplasia and true neoplasias.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"37-58"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18456913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}