{"title":"Effect of high-dose thyrotropic hormone treatment on the cells of the newborn rat thyroid.","authors":"B Madarász, G Csaba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Newborn rats were given 5 I.U. thyrotropic hormone (TSH) either in a single dose or in daily 1 I.U. doses for 5 days. The treatment resulted in the activation of only certain cells of the follicular epithelium. This suggests that the thyroid is responsive in newborn age but not all its cells react. The differences in the response to TSH may be due to different timing of receptor maturation, to the phasic nature of response and to the uneven presence of receptors. It is assumed that cells possessing receptors multiply to form the mature tissue.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"29 2-3","pages":"213-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18328507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Definition of multiple congenital abnormalities.","authors":"A Czeizel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The recommended definition of multiple congenital abnormalities is \"a concurrence of (1) two or more (2) different (i.e. different localized errors in morphogenesis) (3) major congenital abnormalities in the same person\". The baseline data of multiple congenital abnormalities in the Surveillance of the Hungarian Congenital Anomalies, 1970-1976, are shown.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"29 2-3","pages":"251-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18328511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Morphology of cholecystitis and gallstone formation.","authors":"Z Soustek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One thousand gallbladders received from cholecystectomies were analyzed microscopically. Regarding the clinical symptoms the morphological signs of acute and chronic cholecystitis were established. Microscopic changes typical of acute cholecystitis were oedema, haemorrhage and necrosis; and of chronic cholecystitis, sclerosis, presence of haemosiderin pigment and scars. The initial injury of the gallbladder is caused by an angioneurotic reaction (vasospasm and vasodilation) taking place in the bed of the cystic artery during the biliary colic. Acute lesions in the gallbladder are the result of a stress-reaction which takes place in the wall of the biliary tract. Microscopic analysis of the content of removed gallbladder displayed the beginning of gallstone formation. The gallstones are considered a secondary complication of processes which occur in the gallbladder wall during biliary colic. The succession of separate factors which have a role in cholecystitis and cholelithiasis are specified. A new therapeutic approach, treatment with antihistaminics is proposed, to block the angioneurotic reaction and to prevent the progression of biliary tract disease and the formation of gallstones.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"29 2-3","pages":"127-40"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18328503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fine structural study of the posterior pituitary after destruction of the hypophysial stalk in the rat.","authors":"I Domokos, F A László, J M Bilbao, K Kovács","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Electrolytic destruction of the pituitary stalk in rats markedly affected their water metabolism and induced ultrastructural changes in the posterior pituitary. The urinary output increased for 1-2 days after surgery. Subsequently polyuria and polydipsia temporarily decreased and vasopressin excretion with the urine increased. This oliguric interphase was followed by permanent polyuria and polydipsia. No ultrastructural changes were apparent for a few hours after surgery, but 3-5 days later the number of electron-dense granules of the axons decreased and conglomerated in the form of multilamellar bodies. Phagocytic and excretory phenomena were observed in the cytoplasm of endothelial cells and pericytes. The nuclei of pituicytes became loosened, and 5 days following surgery the mitochondria showed swelling and ruptures. The Golgi apparatus and the RER were prominent at 14 days, while degenerative lipid droplets accumulated in the cytoplasm. The fine structural findings, in agreement with the functional observations, support the assumption that the oliguric interphase is due to excessive discharge of vasopressin from the degenerating neural lobe of the pituitary.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"29 2-3","pages":"195-202"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18328505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Hajós, P L Woodhams, E Bascó, A Csillag, R Balázs
{"title":"Proliferation of astroglia in the embryonic mouse forebrain as revealed by simultaneous immunocytochemistry and autoradiography.","authors":"F Hajós, P L Woodhams, E Bascó, A Csillag, R Balázs","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Proliferating glial precursors of the embryonic mouse forebrain were labelled with [3H] thymidine autoradiography and immunostained in the same preparation by using antibodies raised against astroglia-specific protein (GFAP). Results indicate that mature fibrous forms of astroglia are capable of proliferation.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"29 4","pages":"361-4"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18089415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The modular construction of the neuropil in the substantia gelatinosa of the cat's spinal cord. A computer aided analysis of Golgi specimens.","authors":"M Réthelyi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Golgi impregnated spinal cord sections cut in the sagittal plane were used to study the branching pattern, terminal structure and orientation features of terminal axon arborizations in the substantia gelatinosa (lamina II) of the cat. The histological description of the arborizations was supplemented with computer aided quantitative three-dimensional analysis. Six types of axon arborizations could be distinguished among the 31 arborizations collected from C4 and L4 spinal segments. One type was tentatively identified as terminals of non-myelinated primary afferent fibres (Class I arborizations), while the others (Class II arborizations) were suggested to belong to thin myelinated primary afferent fibres, to descending tract fibres and to spinal interneurons. Arborizations differed in branching pattern and in the thickness of the branches. They possessed several terminal and en passant thickenings (up to 75) which were interpreted as presynaptic sites. The arborizations were confined to long and narrow sagittal sheets of the neuropil. These sheets were tilted from the sagittal plane but their rostro-caudal axis lined up exactly parallel to the axis of the spinal cord. The dimensions of the elongated brick-shaped territories encompassing the presynaptic sites of the arborizations were measured. The average values of 10 Class I trees were 526 micrometer in length, 53 micrometer in dorso-ventral direction and 17 micrometer in width (medio-lateral dimension). Class II trees were generally shorter but wider. Trees were found occasionally to arborize in two adjacent sheets. Arborizations with partially or totally overlapping branches were frequently seen.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"29 1","pages":"1-18"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18316924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The importance of epidemiology in identifying drugs which may cause malformations--with particular reference to drugs containing sex hormones.","authors":"F O Kelsey","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"189-95"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18052803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in nuclear volume of Purkinje cells in the cerebellum of the water frog (Rana Esculenta L.) in the annual cycle.","authors":"K Dziubek, H Lach, S Krawczyk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In sexually mature female and male Rana esculenta L. frogs directly from natural habitat, in six characteristic periods of their life cycle, nuclear volume in Purkinje cells of the cerebellum was determined. Nuclear volume in Purkinje cells changed distinctly in the course of the year. Nuclear volume was greatest in females in the breeding period (3rd decade of May), and in males in the middle of the period of active life (2nd decade of July). Nuclear volume was the smallest at the beginning of hibernation (3rd decade of October).</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"3-9"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18052804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can we make a safe workplace?","authors":"K S Larsson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 1-2","pages":"135-8"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18207564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of glutaurine on the pineal gland of the rat.","authors":"L Feuer, B Madarász, F Sudár, G Csaba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Glutaurine (gamma-L-glutamyl-taurine), the recently discovered hormone of the parathyroid enhances the aggregation and subsequent degeneration of mitochondria in the pinealocyte processes of the rat pineal gland. It also stimulates autophagy, probably through its general lysosome activating effect.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 3","pages":"233-42"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18456916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}