{"title":"Ultrastructure of the rat tracheal epithelium in leukoelastase-induced emphysema.","authors":"J Appel, E Tarján, L Petö","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"30 2","pages":"135-41"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17973574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response of rat aortic adventitial fibroblasts to oestradiol treatment in vivo. Role of the cell tubulin system.","authors":"G N Chaldakov, A Kádár","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The fine morphological response was studied of rat aortic adventitial fibroblasts to oestradiol treatment in vivo. Fibroblasts from control rats revealed a well-developed Golgi complex, rough endoplasmic reticulum and cytoplasmic microtubules. Golgi-related vacuoles, elongated and flattened rough endoplasmic reticulum cisterns and microtubules associated with both these organelles were found in these cells. In contrast, dilated rough endoplasmic reticulum cisterns mainly of the vacuolar type were a conspicuous finding in fibroblasts from oestradiol treated rats. The Golgi complex was less expressed, and these cells contained no microtubules. The cytoplasmic microtubules and/or membrane bound tubulin (rough endoplasmic reticulum cisternal membrane bound tubulin) are suggested to be the cell targets on which oestradiol exerts its primary, cholchicine-like effect, resulting in the cellular response of rat aortic adventitial fibroblasts, in a dilatation of the cisterns of rough endoplasmic reticulum.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":" ","pages":"27-34"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35263290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral leukoplakia. A histopathological study.","authors":"I Rodriguez-Pérez, J Bánóczy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Histological sections from 100 leukoplakia patients were analyzed in order to define the characteristics of epithelial and connective tissue alterations and the possible correlation of these changes. Parakeratosis was found in 39% of the cases, orthokeratosis in 24% and both types of keratinization in 34% of the cases. The most characteristic alteration of the thickness of the epithelium was hyperplasia in 81% of the cases. Epithelial dysplasia was present in 27% of the samples. A chronic inflammatory infiltration was generally present in the subepithelial region and in some cases within the epithelium. An increase in the number of these cells related to hyperplasia, parakeratosis and dysplasia has also been found. Our results may be interpreted as a possible relation between epithelial and connective tissue changes in leukoplakia lesions.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"30 3-4","pages":"289-98"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18183480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overlapping effect of follicle stimulating hormone (FSH) and thyrotropin (TSH) on the ultrastructure of immature chicken testes.","authors":"O Dobozy, F Sudár, M A Shahin, G Csaba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In newly hatched chicken testes the gonadotropin receptors due to their immaturity are not specific but still structurally versatile and so they can bind both FSH and TSH which have a chemically related structure. The functional overlapping effect of FSH and TSH on the ultrastructure of Sertoli and Leydig cells of immature chicken testes was investigated. The activity of Sertoli cells was increased by FSH treatment and this increase correlated well with the amount of SER and RER in cells and with their increased surface activity. The vacuolization and degeneration observed at the apical part of the cells may refer to the formation of testicular tubules. After TSH treatment cell activity increased and in addition a considerable increase in RER and lipid droplets was observed. Fenestrated cisternae were often found in the Sertoli cells of the treated animals. In the Leydig cells, both hormones increased lysosomal activity and the number of lipid droplets. After FSH treatment the amount of SER increased while after TSH treatment the Golgi activity.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"30 1","pages":"11-26"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17859217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Light, fluorescence and electron microscopic observations on vitamin A storing cells in allyl-alcohol induced liver damage.","authors":"G Vajta, L Kovács, K Lapis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Earlier studies have described vitamin A accumulation in perisinusoidal Ito cells, but not in portal fibroblasts. The aim of our experiments was to examine whether vitamin A pretreatment is really suitable for the distinction of the two cell groups, and to find out how these cells respond to the periportal injury caused by allyl-alcohol. Using very high doses of vitamin A we demonstrated that the portal fibroblasts, similarly to Ito cells, are able to store vitamin A, therefore in chronic liver injuries, when the lobular and sinusoidal structure is damaged, no difference can be seen between the two groups of cells (using the method suggested by the literature, so far). Our results suggest that both Ito cells and the fibroblasts in the portal region play an important role in the fibrogenesis following allyl-alcohol induced liver injury.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"30 3-4","pages":"309-17"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18183481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experimental pneumoconiosis due to dusts of ore mines, I.","authors":"E Tátrai, M Timár, P Sass, Z Adamis, G Ungváry","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Male CFY rats were injected into their trachea with a suspension of dust of ore mine dead rock of high quartz content and mixed composition (particle size: 0-60 micrometers). Three and six months after treatment, foreign body granulation and after twelve months a non-fibrotic diffuse lung disease was seen in the animals. After twelve months of exposure, non-specific, mature sinus histiocytosis and small focal epitheloid cell reaction were found to develop in the cervical, lung-hilar and retroperitoneal lymph nodes. The histopathological changes were compared with those seen in experimental silicosis induced by DQ12 quartz. It is concluded that the hazardous effect of industrial dusts is not identical with their fibrogenic effect.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":" ","pages":"79-87"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35263199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mycosis fungoides: electron microscopic studies.","authors":"E Zombai","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":" ","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35263289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Importance of cell-to-cell contact and transfer in white cell activity.","authors":"J Illés, L Varga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Formation of cell junctions and the occurrence of cell-to-cell transfer through these was examined in mixed cultures of PK 15 pig kidney and mouse peritoneal cells. Under standardized conditions of experiment, a close contact developed between peritoneal and target cells within 90 min. Light and scanning electron microscopic examinations of the area of close contact indicated extension of cytoplasmic processes from peritoneal cells towards the nucleoli of target cells. The size and localization of the nucleolus and the incorporation of a considerable amount of label by the nucleolar associated chromatin also indicated the decisive role of the nucleolus in the events following upon the establishment of close contact. Autoradiographic examinations showed that part of the 6-3H-thymidine labelled material migrated from the nucleus of target cells into the cytoplasm of peritoneal cells within 30 min. A greater cytoplasmic accumulation of label took place in peritoneal cells exclusively in the presence of actinomycin-D, indicating a rapid breakdown of transferred material under normal conditions. The development of cell-to-cell contact and transfer was found to depend greatly on the composition of the nutrient medium.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"30 2","pages":"143-50"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18034312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Topographical patterns of ultrastructural changes in the rat brain during methionine sulphoximine convulsions.","authors":"L Szegedy, I Balogh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ultrastructure of the cerebral and cerebellar cortex, hippocampus and nucleus facialis was examined in albino rats during MSO convulsions. Three, 6 and 12 h after peritoneal injection of the drug (600 mg/kg) perfusion and dissection were done. Convulsions appeared 4-5 h, status epilepticus 8-9 h after drug administration. Following the onset of clinical seizures, the mitochondria of the neurons became severely damaged. The vesicles and cisterns of the Golgi complex and the endoplasmic reticulum dilated considerably. In the synapses the vesicles were packed together, their number gradually decreased. The astroglia became highly oedematous. During status epilepticus, dark cells and a thickening of the synaptic membranes could be seen beside the above alterations. The morphological changes were most prominent in the cerebellar cortex and in the h1 area of the hippocampus. The neuronal structure of the cerebral cortex was the least damaged.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"30 2","pages":"187-98"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18180278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Secretory features of chondrocytes related to morphogenesis of the elastic elements in the auricular cartilage.","authors":"M Gabrovska, V Vancov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The well-developed secreting vacuolar system is a characteristic feature of all chondrocytes (CH) during prenatal and early postnatal ontogenesis as well as of the CH near the perichondrium in the adult rat's auricular cartilage. Two kinds of secretion vacuoles exist, dense vacuole (DV) and electron lucent vacuoles (LV). The DV are heterogeneous in size, matrix appearance and origin. The factors (organ necessities and chemical maturation) responsible for the DV matrix heterogeneity are discussed. The presence of dilated rough endoplasmic cisternae with local parts of their cisternal surfaces without bound ribosomes suggest the existence of a direct secretory pathway which bypasses the Golgi complex. During prenatal ontogenesis the extracellular matrix of the auricular cartilage consists of bundles of elastic microfibrils and primary elastic fibres. The elastic microfibrils are tubular structures with a wall composed of 3-5 subunits. After birth the primary elastic fibres are joined to form intercellular septae. The presence of matrix vesicles is discussed with regard to the fine differentiation of the auricular elastic system by their lysosomal activity.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"30 2","pages":"127-34"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17942149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}