3D printing in medicine最新文献

{"title":"Correction to: Design, printing optimization, and material testing of a 3D-printed nasal osteotomy task trainer.","authors":"Lauren Schlegel, Eric Malani, Sara Belko, Ayan Kumar, Eric Barbarite, Howard Krein, Ryan Hefelfnger, Morgan Hutchinson, Robert Pugliese","doi":"10.1186/s41205-023-00188-6","DOIUrl":"10.1186/s41205-023-00188-6","url":null,"abstract":"","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10406729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an individual helmet orthosis for infants based on a 3D scan.","authors":"Fabian Kropla, Martin Hoffmann, Dirk Winkler, Matthias Krause, Sebastian Scholz, Ronny Grunert","doi":"10.1186/s41205-023-00187-7","DOIUrl":"10.1186/s41205-023-00187-7","url":null,"abstract":"<p><p>An early childhood skull deformity can have long-term health and aesthetic consequences for the growing toddler. Individual helmet therapy aims at a healthy growth of the skull shape, although not every helmet shape guarantees an optimal result. To ensure an optimal fit, a scanning procedure based on a hand-held surface scanner was evaluated.The new helmet orthosis has an inner layer adapted to the shape of the head, which can be exchanged depending on the growth stage without changing the outer layer.In collaboration with surgeons and engineers, a new helmet orthosis concept was developed that is intended to offer improvements in wearing comfort, overall weight, fit and user-friendliness compared to conventional systems. In the course of the development process and in constant exchange with parents, a multi-layer helmet system with generous perforations was created using additive manufacturing processes. The new helmet shape promises easier handling, especially through the closure system.The helmet shape developed in this study is of high quality, especially in terms of fitting accuracy. Unpleasant perspiration is significantly reduced. The integration of the closure as a direct component of the helmet represents a secure closure option.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"22"},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10045529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generative AI for medical 3D printing: a comparison of ChatGPT outputs to reference standard education.","authors":"Aakanksha Sriwastwa,&nbsp;Prashanth Ravi,&nbsp;Andrew Emmert,&nbsp;Shivum Chokshi,&nbsp;Shayne Kondor,&nbsp;Kashish Dhal,&nbsp;Parimal Patel,&nbsp;Leonid L Chepelev,&nbsp;Frank J Rybicki,&nbsp;Rajul Gupta","doi":"10.1186/s41205-023-00186-8","DOIUrl":"https://doi.org/10.1186/s41205-023-00186-8","url":null,"abstract":"","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9927764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, printing optimization, and material testing of a 3D-printed nasal osteotomy task trainer.","authors":"Lauren Schlegel, Eric Malani, Sara Belko, Ayan Kumar, Eric Barbarite, Howard Krein, Ryan Heffelfinger, Morgan Hutchinson, Robert Pugliese","doi":"10.1186/s41205-023-00185-9","DOIUrl":"10.1186/s41205-023-00185-9","url":null,"abstract":"<p><strong>Background: </strong>For difficult or rare procedures, simulation offers an opportunity to provide education and training. In developing an adequate model to utilize in simulation, 3D printing has emerged as a useful technology to provide detailed, accessible, and high-fidelity models. Nasal osteotomy is an essential step in many rhinoplasty surgeries, yet it can be challenging to perform and difficult to receive adequate exposure to this nuanced portion of the procedure. As it currently stands, there are limited opportunities to practice nasal osteotomy due to the reliance on cadaveric bones, which are expensive, difficult to obtain, and require appropriate facilities and personnel. While previous designs have been developed, these models leave room for improvement in printing efficiency, cost, and material performance. This manuscript aims to describe the methodology for the design of an updated nasal osteotomy training model derived from anatomic data and optimized for printability, usability, and fidelity. Additionally, an analysis of multiple commercially available 3D printing materials and technologies was conducted to determine which offered superior equivalency to bone.</p><p><strong>Methods: </strong>This model was updated from a first-generation model previously described to include a more usable base and form, reduce irrelevant structures, and optimize geometry for 3D printing, while maintaining the nasal bones with added stabilizers essential for function and fidelity. For the material comparison, this updated model was printed in five materials: Ultimaker Polylactic Acid, 3D Printlife ALGA, 3DXTECH SimuBone, FibreTuff, and FormLabs Durable V2. Facial plastic surgeons tested the models in a blinded, randomized fashion and completed surveys assessing tactile feedback, audio feedback, material limitation, and overall value.</p><p><strong>Results: </strong>A model optimizing printability while maintaining quality in the area of interest was developed. In the material comparison, SimuBone emerged as the top choice amongst the evaluating physicians in an experience-based subjective comparison to human bone during a simulated osteotomy procedure using the updated model.</p><p><strong>Conclusion: </strong>The updated midface model that was user-centered, low-cost, and printable was designed. In material testing, Simubone was rated above other materials to have a more realistic feel.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"20"},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10020818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of 3D printed patient-specific skull implants based on 3d surface scans.","authors":"Fabian Kropla,&nbsp;Dirk Winkler,&nbsp;Dirk Lindner,&nbsp;Patrick Knorr,&nbsp;Sebastian Scholz,&nbsp;Ronny Grunert","doi":"10.1186/s41205-023-00183-x","DOIUrl":"https://doi.org/10.1186/s41205-023-00183-x","url":null,"abstract":"<p><p>Sometimes cranioplasty is necessary to reconstruct skull bone defects after a neurosurgical operation. If an autologous bone is unavailable, alloplastic materials are used. The standard technical approach for the fabrication of cranial implants is based on 3D imaging by computed tomography using the defect and the contralateral site. A new approach uses 3D surface scans, which accurately replicate the curvature of the removed bone flap. For this purpose, the removed bone flap is scanned intraoperatively and digitized accordingly. When using a design procedure developed for this purpose creating a patient-specific implant for each bone flap shape in short time is possible. The designed skull implants have complex free-form surfaces analogous to the curvature of the skull, which is why additive manufacturing is the ideal manufacturing technology here. In this study, we will describe the intraoperative procedure for the acquisition of scanned data and its further processing up to the creation of the implant.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9744559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and Development of a Novel 3-D Printed External Fixation Device for Fracture Stabilization.","authors":"Nathan Wm Skelley","doi":"10.1186/s41205-023-00179-7","DOIUrl":"https://doi.org/10.1186/s41205-023-00179-7","url":null,"abstract":"<p><strong>Background: </strong>An external fixator is an orthopaedic device used to stabilize long bone fractures after high energy trauma. These devices are external to the body and fixed to metal pins going into non-injured areas of bone. They serve a mechanical function to maintain length, prevent bending, and resist torque forces about the fracture area. The purpose of this manuscript is to describe a design and prototyping process creating a low-cost entirely 3-D printed external fixator for fracture stabilization of extremity fractures. The secondary objective of this manuscript is to facilitate future advancements, modifications, and innovations in this area of 3-D printing in medicine.</p><p><strong>Methods: </strong>This manuscript describes the computer aided design process using desktop fused deposition modeling to create a 3-D printed external fixator system designed for fracture stabilization. The device was created using the orthopaedic goals for fracture stabilization with external fixation. However, special modifications and considerations had to be accounted for given the limitations of desktop fused deposition modeling and 3-D printing with plastic polymers.</p><p><strong>Results: </strong>The presented device accomplishes the goals of creating a construct that can be attached to 5.0 mm metal pins, allows for modularity in placement orientations, and facilitates adjustable lengths for fracture care. Furthermore, the device provides length stability, prevention of bending, and resists torque forces. The device can be printed on a desktop 3-D printer using standard low-cost polylactic acid filament. The print time is less than two days and can be completed on one print bed platform.</p><p><strong>Conclusions: </strong>The presented device is a potential alternative for fracture stabilization. The concept of a desktop 3-D printed external fixator design and method of production allows for numerous diverse applications. This includes assisting areas with remote or limited access to advanced medical care and large-scale natural disasters or global conflicts where large volumes of fractures exceed the local medical supply chain capabilities. The presented device creates a foundation for future devices and innovations in this fracture care space. Further research is needed on mechanical testing and clinical outcomes with this design and initiative in fracture care before clinical application.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9642399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elbow hemiarthroplasty with a 3D-printed prosthesis for distal humeral bone defects after tumor excision: a case report.","authors":"Yingkang Zhu,&nbsp;Shuo Gong,&nbsp;Jin Dai,&nbsp;Lei Zhou","doi":"10.1186/s41205-023-00178-8","DOIUrl":"https://doi.org/10.1186/s41205-023-00178-8","url":null,"abstract":"<p><strong>Introduction: </strong>The distal humerus is a rare site for primary and metastatic bone tumors. Due to the scarcity of cases and lack of standardized surgical strategies, it is often difficult for surgeons to choose the right choice. The application of a 3D-printed prosthesis with hemiarthroplasty for the treatment of the distal humerus after tumor resection can be a very effective option.</p><p><strong>Case presentation: </strong>We present a clinical case of a 3D-printed distal humeral prosthesis for the treatment of bone defects caused by metastatic bone tumors. The preoperative evaluation was aggressively performed, and the decision was made to distal humeral hemiarthroplasty (DHH) after wide resection of the tumor segment bone. Processing of the Digital Imaging and Communications in Medicine (DICOM) data from CT scans performed after mirror conversion using CT data of the contralateral humerus, we designed a 3D-printed distal humeral prosthesis with hemiarthroplasty. After reconstruction of bone and surrounding soft tissue by the 3D-printed prosthesis combined with the LARS ligament and regular follow-up for 12 months, the patient had an MSTS-93 score of 29 and an MEP of 100, which reached a good level, and the patient was fully competent in normal daily activities.</p><p><strong>Conclusions: </strong>Our results show that the 3D-printed modular prosthesis with hemiarthroplasty is a very effective option for cases of large elbow bone defects due to primary bone tumors or metastatic disease. However, careful preoperative preparation is required for the best outcome. Careful preoperative preparation and long-term follow-up are essential for the best outcome.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"18"},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9642404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deformable titanium for acetabular revision surgery: a proof of concept.","authors":"J Magré,&nbsp;K Willemsen,&nbsp;H M A Kolken,&nbsp;A A Zadpoor,&nbsp;H C Vogely,&nbsp;B C H van der Wal,&nbsp;H Weinans","doi":"10.1186/s41205-023-00177-9","DOIUrl":"https://doi.org/10.1186/s41205-023-00177-9","url":null,"abstract":"<p><p>Custom-made triflange acetabular implants are increasingly used in complex revision surgery where supporting bone stock is diminished. In most cases these triflange cups induce stress-shielding. A new concept for the triflange is introduced that uses deformable porous titanium to redirect forces from the acetabular rim to the bone stock behind the implant and thereby reduces further stress-shielding. This concept is tested for deformability and primary stability.Three different designs of highly porous titanium cylinders were tested under compression to determine their mechanical properties. The most promising design was used to design five acetabular implants either by incorporating a deformable layer at the back of the implant or by adding a separate generic deformable mesh behind the implant. All implants were inserted into sawbones with acetabular defects followed by a cyclic compression test of 1800N for 1000 cycles.The design with a cell size of 4 mm and 0.2 mm strut thickness performed the best and was applied for the design of the acetabular implants. An immediate primary fixation was realized in all three implants with an incorporated deformable layer. One of the two implants with a separate deformable mesh needed fixation with screws. Cyclic tests revealed an average additional implant subsidence of 0.25 mm that occurred in the first 1000 cycles with minimal further subsidence thereafter.It is possible to realize primary implant fixation and stability in simulated large acetabular revision surgery using a deformable titanium layer behind the cup. Additional research is needed for further implementation of such implants in the clinic.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9613532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D Printed Orthopaedic External Fixation Devices: A Systematic Review.","authors":"Hunter A O'Connor,&nbsp;Luke W Adams,&nbsp;Lisa N MacFadden,&nbsp;Nathan Wm Skelley","doi":"10.1186/s41205-023-00180-0","DOIUrl":"https://doi.org/10.1186/s41205-023-00180-0","url":null,"abstract":"<p><strong>Background: </strong>External fixators are complex, expensive orthopaedic devices used to stabilize high-energy and complex fractures of the extremities. Although the technology has advanced dramatically over the last several decades, the mechanical goals for fracture stabilization of these devices have remained unchanged. Three-dimensional (3D) printing technology has the potential to advance the practice and access to external fixation devices in orthopaedics. This publication aims to systematically review and synthesize the current literature on 3D printed external fixation devices for managing orthopaedic trauma fractures.</p><p><strong>Methods: </strong>The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) protocols were followed for this manuscript with minor exceptions. PubMed, Embase, Cochrane Review, Google Scholar, and Scopus online databases were systematically searched. Two independent reviewers screened the search results based on predetermined inclusion and exclusion criteria related to 3D printing and external fixation of fractures.</p><p><strong>Results: </strong>Nine studies met the inclusion criteria. These included one mechanical testing study, two computational simulation studies, three feasibility studies, and three clinical case studies. Fixator designs and materials varied significantly between authors. Mechanical testing revealed similar strength to traditional metal external fixators. Across all clinical studies, five patients underwent definitive treatment with 3D printed external fixators. They all had satisfactory reduction and healing with no reported complications.</p><p><strong>Conclusions: </strong>The current literature on this topic is heterogeneous, with highly variable external fixator designs and testing techniques. A small and limited number of studies in the scientific literature have analyzed the use of 3D printing in this area of orthopaedic surgery. 3D printed external fixation design advancements have yielded promising results in several small clinical case studies. However, additional studies on a larger scale with standardized testing and reporting techniques are needed.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9598245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives on medical 3D printing at the point-of-care from the new European 3D Printing Special Interest Group.","authors":"Giovanni Biglino,&nbsp;Carina Hopfner,&nbsp;Joakim Lindhardt,&nbsp;Francesco Moscato,&nbsp;Josep Munuera,&nbsp;Gunpreet Oberoi,&nbsp;Alessandro Tel,&nbsp;Arnau Valls Esteve","doi":"10.1186/s41205-022-00167-3","DOIUrl":"https://doi.org/10.1186/s41205-022-00167-3","url":null,"abstract":"<p><p>This editorial presents the vision for the newly formed (2022) European 3D Special Interest Group (EU3DSIG) in the landscape of medical 3D printing. There are four areas of work identified by the EU3DSIG in the current landscape, namely: 1) creating and fostering communication channels among researches, clinicians and industry, 2) generating awareness of hospitals point-of-care 3D technologies; 3) knowledge sharing and education; 4) regulation, registry and reimbursement models.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"9 1","pages":"14"},"PeriodicalIF":0.0,"publicationDate":"2023-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9479361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}