3D printing in medicine最新文献

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Intra-hospital patient-specific 3D printed surgical guide for patients with thoracic scoliotic deformities, the collaboration between engineer and surgeon. 针对胸椎侧凸畸形患者的院内患者特异性3D打印手术指南,工程师和外科医生的合作。
IF 3.2
3D printing in medicine Pub Date : 2025-07-21 DOI: 10.1186/s41205-025-00279-6
M Suffo, M Quiroga-De Castro, L Galán-Romero, P Andrés-Cano
{"title":"Intra-hospital patient-specific 3D printed surgical guide for patients with thoracic scoliotic deformities, the collaboration between engineer and surgeon.","authors":"M Suffo, M Quiroga-De Castro, L Galán-Romero, P Andrés-Cano","doi":"10.1186/s41205-025-00279-6","DOIUrl":"10.1186/s41205-025-00279-6","url":null,"abstract":"<p><strong>Background: </strong>This study validates the intra-hospital design and 3D printing process of personalized surgical guides to enhance the accuracy of pedicle screw insertion in patients with thoracic scoliotic deformities. It introduces a novel collaborative paradigm between surgeons and engineers, aiming to improve efficiency and reduce errors in the manufacturing of patient-specific instruments (PSIs).</p><p><strong>Methods: </strong>The process began with the generation of 3D biomodels of vertebrae from computed tomography scans. Surgical guides were then created using two 3D printing techniques: Fused Filament Fabrication (FFF) with polylactic acid (PLA) and Stereolithography (SLA) with photopolymer resin. Three different prototypes were compared based on multifactorial indicators, including economic cost, macroscopic surface finish, and mechanical stability. The mechanical performance of the guides was evaluated under loads generated during pedicle screw penetration and threading.</p><p><strong>Results and discussions: </strong>PLA models printed using FFF were found to be cheaper and simpler to manufacture than SLA resin models. Despite differences observed under a microscope, PLA models exhibited a macroscopic surface finish comparable to that of SLA resin models. Both materials demonstrated similar mechanical properties, although their values were lower than those reported in the manufacturer's datasheet. Importantly, both types of guides successfully withstood the mechanical loads generated during surgical procedures. The intra-hospital collaboration between engineers and surgeons was identified as a key factor in improving outcomes and reducing error risks, showcasing the benefits of interdisciplinary teamwork.</p><p><strong>Conclusions: </strong>3D-printed PSIs made from PLA using FFF are more cost-effective and quicker to produce compared to SLA resin models, while achieving similar results in surface finish and mechanical stability. The implementation of a collaborative approach between engineers and surgeons within hospital settings enhances the efficiency and accuracy of patient-specific surgical guide manufacturing, offering a promising solution for improving surgical outcomes in thoracic scoliotic deformities.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"40"},"PeriodicalIF":3.2,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Segmentation and finite element analysis in orthopaedic trauma. 骨科创伤的分割与有限元分析。
IF 3.2
3D printing in medicine Pub Date : 2025-07-21 DOI: 10.1186/s41205-025-00284-9
Kevin Y Wang, Alexander R Farid, Simon Comtesse, Arvind G von Keudell
{"title":"Segmentation and finite element analysis in orthopaedic trauma.","authors":"Kevin Y Wang, Alexander R Farid, Simon Comtesse, Arvind G von Keudell","doi":"10.1186/s41205-025-00284-9","DOIUrl":"10.1186/s41205-025-00284-9","url":null,"abstract":"<p><strong>Background: </strong>Finite Element Analysis (FEA) has evolved into a crucial tool in orthopaedic trauma research and clinical practice. This review explores the broad applications of FEA in orthopedic surgery.</p><p><strong>Main body: </strong>FEA involves several steps, including geometry representation, segmentation, 3D rendering, meshing, material property assignment, defining boundary conditions, and specifying contact conditions. The process utilizes patient-specific volumetric data-computed tomography (CT) scan, for example-and aims for a balance between computational efficiency and accuracy. FEA provides valuable outcome measures such as stress distribution, strain quantification, fracture gap motion, failure prediction, and implant stability. These measures aid in evaluating fracture fixation techniques, implant design, and the impact of different fixation strategies. FEA has found applications in femur and proximal humerus fracture fixation, distal femur fracture planning, tibial plateau fractures, and post-traumatic osteoarthritis. It plays a pivotal role in predicting fracture risk, assessing construct stability, and informing surgical decision-making. Additionally, FEA facilitates the development of custom surgical planning and personalized implants. To enhance accuracy, FEA is combined with cadaveric biomechanical analysis, providing a reference-standard representation of in vivo kinematics. Future research should focus on refining FEA models through increased validation using cadaveric models and clinical data.</p><p><strong>Conclusion: </strong>FEA has revolutionized orthopaedic trauma research by offering insights into biomechanics, fracture fixation, and implant design. Integration with cadaveric biomechanical analysis enhances accuracy. Further validation efforts and integration into regular clinical practice are essential for realizing FEA's full potential in individualized patient care. The combination of FEA and cadaveric analysis contributes to a comprehensive understanding of in vivo kinematics, ultimately improving patient outcomes.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"39"},"PeriodicalIF":3.2,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The novel technique for surgical simulation training of patient-specific silicone models of pediatric congenital choledochal cysts. 小儿先天性胆总管囊肿患者特异性硅胶模型的外科模拟训练新技术。
IF 3.2
3D printing in medicine Pub Date : 2025-07-16 DOI: 10.1186/s41205-025-00252-3
Shijiao Lu, Yiming Gong, Shengqian Pan, Jun Liu, Jianfeng Wang, Peng Wang
{"title":"The novel technique for surgical simulation training of patient-specific silicone models of pediatric congenital choledochal cysts.","authors":"Shijiao Lu, Yiming Gong, Shengqian Pan, Jun Liu, Jianfeng Wang, Peng Wang","doi":"10.1186/s41205-025-00252-3","DOIUrl":"10.1186/s41205-025-00252-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study was aimed to design a patient-specific models of pediatric congenital choledochal cysts(CCC) for surgical simulation training.</p><p><strong>Methods: </strong>Seventeen children suffering from CCC were included in this study. Liver and hepatic hilum structures were generated as standard parts by traditional silicone casting after 3D printing via digital imaging. Moreover, the choledochal cyst was produced as an individualized part by the silicone shaking technique and soft resin printing. Afterwards, the two model parts were assembled for laparoscopic surgical simulation. Surgical excision and suturing, and usability were evaluated. P < 0.05 was considered to indicate a significant difference.</p><p><strong>Results: </strong>Compared with those of the digital models, the liver well and hepatic hilum structures produced were more aesthetically pleasing. Moreover, cyst models were produced accordingly. In addition, silicone models have good mechanical properties and lower costs than resins and TPU powder, and silicone models are recommended as useful tools for presurgical simulated planning. The results also showed good feedback of cutting and suturing with good face validity and usability after the simulation was complete.</p><p><strong>Conclusions: </strong>It is feasible that the application of the silicone shaking technique can produce a hollow individualized model of CCC for surgical simulation and medical training.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"37"},"PeriodicalIF":3.2,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12265354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconstruction of a large distal femoral giant cell tumor using a 3D-printed condylar support lattice metal implant and fibular grafts: a novel biomechanical and surgical approach. 使用3d打印髁支撑晶格金属植入物和腓骨移植物重建股骨远端巨大细胞瘤:一种新的生物力学和外科方法。
IF 3.1
3D printing in medicine Pub Date : 2025-07-16 DOI: 10.1186/s41205-025-00282-x
Aashish Chaudhry, Abhishek Kumar Sambharia, Bharat Bahre, Mani Pandey, Tanvi Chawla
{"title":"Reconstruction of a large distal femoral giant cell tumor using a 3D-printed condylar support lattice metal implant and fibular grafts: a novel biomechanical and surgical approach.","authors":"Aashish Chaudhry, Abhishek Kumar Sambharia, Bharat Bahre, Mani Pandey, Tanvi Chawla","doi":"10.1186/s41205-025-00282-x","DOIUrl":"10.1186/s41205-025-00282-x","url":null,"abstract":"<p><p>OBJECTIVE: This study presents a novel approach to reconstructing a large defect in the load-bearing condylar region of distal femur following the surgical removal of a giant cell tumor (GCT). By using advanced 3D printing technology and virtual surgical planning, designing a patient-specific implant (PSI) to replace the defect and integrate a fibular graft for osseointegration, providing cortical bone strength. METHODS: A 40-year-old female patient with recurrent pain and swelling in the left knee was diagnosed with a distal femoral GCT. Imaging studies confirmed a large lytic lesion with cortical thinning. After tumor excision, reconstruction was performed using a 3D-printed lattice metal implant designed for biological and mechanical integration. A 3D printed custom titanium plate was used additionally for structural support and a fibular graft was embedded within the implant for biological union. RESULTS: Postoperative outcomes demonstrated progressive osseointegration, weight-bearing capability, and functional recovery. The patient regained maximum osseointegration with the completion of 6 months and full-strength unrestricted mobility at the end of 18 months postoperatively without recurrence. Radiographic follow-ups confirmed structural integrity and graft incorporation. CONCLUSION: This study illustrates the successful application of a customized lattice metal implant integrated with a fibular graft, demonstrating its feasibility for large tumor-induced defects in weight-bearing regions. </p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"38"},"PeriodicalIF":3.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12265116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine learning-assisted finite element modeling of additively manufactured meta-materials. 增材制造超材料的机器学习辅助有限元建模。
IF 3.2
3D printing in medicine Pub Date : 2025-07-14 DOI: 10.1186/s41205-025-00286-7
Alexander Meynen, Hma Kolken, Michiel Mulier, Amir A Zadpoor, Lennart Scheys
{"title":"Machine learning-assisted finite element modeling of additively manufactured meta-materials.","authors":"Alexander Meynen, Hma Kolken, Michiel Mulier, Amir A Zadpoor, Lennart Scheys","doi":"10.1186/s41205-025-00286-7","DOIUrl":"10.1186/s41205-025-00286-7","url":null,"abstract":"<p><p>Mechanical characterization of three-dimensional (3D) printed meta-biomaterials is rapidly becoming a crucial step in the development of novel medical device concepts, including those used in functionally graded implants for orthopedic applications. Finite element simulations are a valid, FDA-acknowledged alternative to experimental tests, which are time-consuming, expensive, and labor-intensive. However, when applied to 3D-printed meta-biomaterials, state-of-the-art finite element modeling approaches are becoming increasingly complex, while their accuracy remains limited. A critical condition for accurate simulation results is the identification of correct modelling parameters. This study proposes a machine learning-based strategy for identifying model parameters, including material properties and model boundary conditions, to enable accurate simulations of macro-scale mechanical behavior. To achieve this goal, a physics-informed artificial neural network model (PIANN) was developed and trained using data generated through a fully automated finite element modeling workflow. Subsequently, the PIANN model was then tested using real experimental force-displacement data as its input. The experimental data from 3D-printed structures were used to predict the associated parameters for finite element modeling. Finally, the workflow was validated by qualitatively and quantitatively comparing simulation results to the experimental data. Based on these results, we concluded that the proposed workflow could identify model parameters such that the predictions of associated finite element simulations are in agreement with experimental observations. Furthermore, resulting finite element models were found to outperform state-of-the-art models in terms of both quantitative and qualitative accuracy. Therefore, the proposed strategy has the potential to facilitate the broader application of finite element simulations in evaluating 3D-printed parts, in general, and 3D-printed meta-biomaterials, in particular.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"36"},"PeriodicalIF":3.2,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Economic evaluation of the manufacturing of 3D-printed wrist orthoses vs low temperature thermoplastic wrist orthoses. 3d打印腕部矫形器与低温热塑性腕部矫形器制造的经济评估。
IF 3.1
3D printing in medicine Pub Date : 2025-07-03 DOI: 10.1186/s41205-025-00287-6
Marianne von Haller, Louise Couchman, Philipp Honigmann
{"title":"Economic evaluation of the manufacturing of 3D-printed wrist orthoses vs low temperature thermoplastic wrist orthoses.","authors":"Marianne von Haller, Louise Couchman, Philipp Honigmann","doi":"10.1186/s41205-025-00287-6","DOIUrl":"10.1186/s41205-025-00287-6","url":null,"abstract":"<p><p>BACKGROUND: In recent years, three-dimensional (3D) printing has emerged as a new manufacturing technique of custom-fitted orthoses, showing comparable stability, and wearing comfort than traditional orthoses. However, there is a paucity of data on economic aspects of the manufacturing of 3D-printed orthoses (3DPOs). The aim of this study is to economically evaluate the manufacturing process of 3DPOs compared to conventional low-temperature thermoplastic orthoses (LTTOs) in a clinical setting. METHODS: A prospective cost minimisation analysis from a healthcare provider perspective was conducted including 17 wrist orthoses (8 3DPOs and 9 LTTOs). RESULTS: The mean cost per orthosis was significantly higher in 3DPOs (€ 46.54) than in LTTOs (€ 30.28). The main cost factors in 3DPOs were the labour (62.2%) and purchase cost (22.2%), while the material (69.4%) and labour cost (30.6%) were most important in LTTOs. CONCLUSIONS: The high initial investment might be a hurdle in the implementation of 3DPOs in hand rehabilitation, however, lower material cost and less waste is a benefit compared to LTTOs. Large-scale use of the infrastructure and developments in technology might reduce the investments needed in the future. TRIAL REGISTRATION: : not applicable. </p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"35"},"PeriodicalIF":3.1,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12225182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D printed polymers that mimic the mechanical properties of atherosclerotic blood vessels for training models: the advantageous degradation induced by UV radiation and hydrolysis. 3D打印聚合物,模拟动脉粥样硬化血管的机械特性,用于训练模型:紫外线辐射和水解诱导的有利降解。
IF 3.2
3D printing in medicine Pub Date : 2025-07-02 DOI: 10.1186/s41205-025-00288-5
Joana Filipa Henriques, Lino Gonçalves, Ana Martins Amaro, Ana Paula Piedade
{"title":"3D printed polymers that mimic the mechanical properties of atherosclerotic blood vessels for training models: the advantageous degradation induced by UV radiation and hydrolysis.","authors":"Joana Filipa Henriques, Lino Gonçalves, Ana Martins Amaro, Ana Paula Piedade","doi":"10.1186/s41205-025-00288-5","DOIUrl":"10.1186/s41205-025-00288-5","url":null,"abstract":"<p><strong>Background: </strong>Atherosclerosis is a chronic disease characterized by the narrowing and hardening of arteries that may induce serious complications and even sudden death. Percutaneous angioplasty is performed as the main treatment of atherosclerotic-based cardiovascular diseases, which are the leading cause of mortality worldwide. Patient-specific physical models of these vascular conditions would greatly assist percutaneous angioplasty medical training and planning. Such models must be composed of materials that accurately replicate the properties of tissues. However, this mimicking can be challenging due to the complexity and composition of atherosclerotic vasculature. As additive manufacturing allows the production of complex and personalized structures, it provides great potential for manufacturing those models. The application of additive manufacturing in this context is often associated with high production costs, mainly related to material synthesis. Commercial materials could break this limitation, but they are still misaddressed.</p><p><strong>Methods: </strong>Therefore, this work intends to explore the use of three different commercial UV-curable resins to mimic the several types of atherosclerotic vessels. They were manufactured by vat photopolymerisation process, specifically the stereolithography (SLA) technology to mimic atherosclerotic vessels. The mechanical performance of materials and the influence of immersion in phosphate buffered saline (PBS) solution and irradiation with UV light, during different times, were evaluated. Dynamic tensile tests were conducted to study the fatigue resistance of materials under physiological loads.</p><p><strong>Results: </strong>The results showed that immersion in PBS solution enhanced the dynamic mechano-stability. Likewise, irradiation with UV-C light was pointed out as an interesting strategy to adjust the hardness of materials, with the advantage of being a fast and low-cost approach.</p><p><strong>Conclusion: </strong>Comparisons with the literature supported that all used materials are suitable for mimicking the mechanical properties of atherosclerotic vessels, specifically when previously immersed in physiological-simulated fluids, such as PBS.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"34"},"PeriodicalIF":3.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A personalized 3D printed cranial shield using mirror-image modeling: design and clinical assessment. 使用镜像建模的个性化3D打印颅罩:设计和临床评估。
IF 3.2
3D printing in medicine Pub Date : 2025-07-01 DOI: 10.1186/s41205-025-00289-4
Zhongjie Shi, Zhengbo Yuan, Jie Chen, Hongwei Zhu, Hualing Huang, Zhanxiang Wang, Zirui Su
{"title":"A personalized 3D printed cranial shield using mirror-image modeling: design and clinical assessment.","authors":"Zhongjie Shi, Zhengbo Yuan, Jie Chen, Hongwei Zhu, Hualing Huang, Zhanxiang Wang, Zirui Su","doi":"10.1186/s41205-025-00289-4","DOIUrl":"10.1186/s41205-025-00289-4","url":null,"abstract":"<p><strong>Background: </strong>Patients who undergo decompressive craniectomy (DC) are at increased risk of head trauma due to postoperative cranial defects, which not only raise concerns about physical vulnerability but also negatively impact psychological well-being. Conventional protective strategies remain insufficient. This study aimed to develop a personalized, low-cost, three-dimensional (3D) printed external head protection device using mirror-image modeling, and to evaluate its performance in providing physical protection and improving patient-reported outcomes during the post-discharge period.</p><p><strong>Method: </strong>A prospective study was conducted involving 58 patients treated with DC between August 2023 and February 2025 across two neurosurgical centers. Participants were randomly assigned to an observation group (n = 28), who wore a custom-designed 3D printed protective device based on postoperative CT scans, or to a control group (n = 30) without special protective measures. A custom questionnaire was used to assess satisfaction with appearance, willingness to engage in social activities, and fear of accidental impact at weeks 1, 4, and 8 post-discharge. Objective indicators such as fall events, adverse reactions, and device integrity were also recorded.</p><p><strong>Results: </strong>The 3D printed models demonstrated good anatomical fit and structural reliability. At weeks 4 and 8, the observation group showed significantly higher Visual Analog Scale (VAS) scores compared to the control group (P = 0.014 and P = 0.002, respectively), with continuous improvement over time (P < 0.05). The average daily usage time of the device was 4.4 ± 1.2 h. No cases of skin irritation or pressure injuries were reported. One patient in the observation group experienced a fall that caused a minor device crack but no head injury (fall rate: 3.6%). In the control group, two patients fell without head trauma (fall rate: 6.7%).</p><p><strong>Conclusions: </strong>Our findings introduce a personalized, 3D printed external helmet as a new option for cranial protection after decompressive craniectomy. The prototype provided reliable mechanical shielding, conformed closely to each patient's skull contour, and was well tolerated. By reducing physical risk, boosting confidence in appearance, and alleviating anxiety during the interval before cranioplasty, the device may bridge a critical safety and psycho-social gap in early rehabilitation.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"32"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12210813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mandibular reconstruction outcomes for in-house patient-specific solutions. 下颌骨重建的结果为内部患者特定的解决方案。
IF 3.2
3D printing in medicine Pub Date : 2025-07-01 DOI: 10.1186/s41205-025-00280-z
Matthew D Marquardt, Erin Cowen, Rachel Fenberg, Natalia von Windheim, Margaret Lashutka, Abigail E Reid, Amit Agarwal, Enver K Ozer, Ricardo L Carrau, James W Rocco, Catherine T Haring, Stephen Y Kang, Nolan B Seim, Matthew O Old, Kyle K VanKoevering
{"title":"Mandibular reconstruction outcomes for in-house patient-specific solutions.","authors":"Matthew D Marquardt, Erin Cowen, Rachel Fenberg, Natalia von Windheim, Margaret Lashutka, Abigail E Reid, Amit Agarwal, Enver K Ozer, Ricardo L Carrau, James W Rocco, Catherine T Haring, Stephen Y Kang, Nolan B Seim, Matthew O Old, Kyle K VanKoevering","doi":"10.1186/s41205-025-00280-z","DOIUrl":"10.1186/s41205-025-00280-z","url":null,"abstract":"<p><strong>Background: </strong>Segmental mandibulectomy and mandibular reconstruction are often performed for various benign and malignant head and neck conditions. Standard of care reconstruction involves titanium plate fixation with tissue transfer. The advent of computer-aided design and manufacturing (CAD/CAM) has enhanced aesthetic and functional outcomes in mandibular reconstruction by enabling patient-specific solutions like 3D-printed anatomic models. At an increasing number of institutions, these solutions can be produced in-house via point-of-care manufacturing. Since little has been published on the accuracy and outcomes of this approach, this study sought to evaluate the reconstructive accuracy and clinical outcomes of patients who received in-house patient-specific mandible models.</p><p><strong>Methods: </strong>A retrospective chart review was conducted of 44 patients from a large midwestern academic medical center who received point-of-care patient-specific 3D printed models to assist in segmental mandibulectomy and reconstruction from December 2020 to June 2022. CAD/CAM models were produced from pre- and post-operative CT scans. Pre- and post-operative scans were aligned using a novel reference landmark-the maxilla. Measurements were taken by two different researchers at the mandibular condyles, coronoids, angles as well as a plane from the maxilla to the mandibular pogonion to determine reconstructive accuracy. Inter-rater reliability was assessed via intraclass correlation coefficient. Demographic, clinical, surgical, and radiographic variables were also collected to profile cohort characteristics and outcomes.</p><p><strong>Results: </strong>After exclusions due to poor or no post-operative imaging, 25 patients were included in the final analysis. Squamous cell carcinoma (n = 19) was the most common pathology, and males (n = 18) were represented more than females (n = 7). 96% (24/25) of patients had good plate adaptation and 96% (24/25) had good osteotomy adaptation. Reconstruction accuracy measured by comparing preoperative to postoperative anatomic alignment was very good, with an average absolute difference across all patients of only 3.10 mm. Inter-rater reliability between measurements was high with an average 0.98 intraclass correlation coefficient.</p><p><strong>Conclusions: </strong>We present a novel method for measuring mandibular reconstruction accuracy through the use of the maxilla as the anatomic landmark. Furthermore, our profile of patients who underwent segmental mandibulectomy and reconstruction with the assistance of in-house produced 3D printed patient-specific models appears to result in suitable anatomic alignment of the reconstructed mandible and produce good clinical outcomes.</p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"31"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D printing and acute maxillofacial trauma: an overview of the literature. 3D打印和急性颌面创伤:文献综述。
IF 3.1
3D printing in medicine Pub Date : 2025-07-01 DOI: 10.1186/s41205-025-00285-8
E Bertin, C Coussens, E Brumpt, C Meyer, A Louvrier
{"title":"3D printing and acute maxillofacial trauma: an overview of the literature.","authors":"E Bertin, C Coussens, E Brumpt, C Meyer, A Louvrier","doi":"10.1186/s41205-025-00285-8","DOIUrl":"10.1186/s41205-025-00285-8","url":null,"abstract":"<p><p>BACKGROUND: The consequences of maxillofacial injuries are functionals and aesthetics. The initial treatment must lead to consolidation without any sequelae (complete healing with no clinical symptoms). 3D printing is increasingly used in maxillofacial surgery, but data on its use in the initial phase of trauma is scarce. METHOD: We conducted a bibliographic search in PubMed’s electronic database with the following terms: maxillofacial traumatology, maxillofacial fracture, mandible fracture, maxillary fracture, zygoma fracture, LeFort fracture, fracture of the naso-ethmoido-maxillo-fronto-orbital complex, orbital fracture, nasal bones fracture, frontal sinus fracture, 3D printing, 3-dimensional printing, virtual planning. Data included study characteristics, material used, evaluation criteria, advantages, and disadvantages of the use of 3D printing. RESULTS: Fifty-six articles were selected and divided into 3 groups (multiple facial fractures, mandible fractures, and zygoma and/or orbital wall fractures). There were mainly retrospective studies and case reports, and the authors used CT scans to plan surgery. Printed objects were occlusal splints (n = 11 from fractures with occlusal disorders), and a skull model with fracture or after virtual reduction (n = 42). 3D printing permits a reduction in operating time from 15 to 60 min. The authors often used them to preshape plates, and the evaluation criteria were essentially radiologic (position of the implant compared to planning, precision of the reduction, orbital volume, etc.). CONCLUSION: The use of 3D printing permits reduced operating times and better visibility of movements. However, this often requires a post-operative CT scan, and little account is taken of clinical criteria. 3D printing and acute maxillofacial trauma: an overview of the literature. </p>","PeriodicalId":72036,"journal":{"name":"3D printing in medicine","volume":"11 1","pages":"33"},"PeriodicalIF":3.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12217379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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