National Academy Science Letters最新文献_第6页

Efavirenz-Induced Hepatic Changes in the Fetus of Swiss Albino Mice 依非韦伦诱导的瑞士白化小鼠胎儿肝脏变化

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-22 DOI: 10.1007/s40009-023-01387-9

Anand Mishra, Akansha Sharma, Archna Yadav, V. Harsha, Amit Kumar Nayak, Kapil Kumar Malviya, Prasenjit Bose, Umesh Choudhary, Surendra Kumar Pandey

{"title":"Efavirenz-Induced Hepatic Changes in the Fetus of Swiss Albino Mice","authors":"Anand Mishra, Akansha Sharma, Archna Yadav, V. Harsha, Amit Kumar Nayak, Kapil Kumar Malviya, Prasenjit Bose, Umesh Choudhary, Surendra Kumar Pandey","doi":"10.1007/s40009-023-01387-9","DOIUrl":"10.1007/s40009-023-01387-9","url":null,"abstract":"<div><p>Efavirenz (EFV) is a non-nucleoside reverse transcriptase inhibitor that binds to reverse transcriptase enzyme resulting in its allosteric inhibition. It is a constituent of highly active antiretroviral therapy (HAART) used for preventing maternal-to-child transmission of the HIV virus. Efavirenz has been classified as a class D drug which means that there have been reports of reproductive toxicity induced by it and should be used only when potential benefits outweigh the risk. Pregnant Swiss albino mice were divided into the following groups: control group (C): mice treated with distilled water (6 mice) and treated group (T): mice treated with EFV (50 mg/kg) (6 mice). All the mice were given the drug and distilled water from gestation days 6–15 by oral route. On the 18th day of gestation, each group’s mice blood was collected from retro-orbital sinus for biochemical assay, and then, they were killed by cervical dislocation. Laparotomy was done to resect out the fetuses which were weighed, and then fixed in 10% formalin. Their liver was processed for histological study under H&E and PAS stain. The microscopic study of the liver showed the reduced density of hepatoblasts and progenitor cells, deficient sinusoid formation and destruction of the central vein in the treated group as compared to the control. A significant reduction in the weight of the fetal liver was observed. The values of SGOT, SGPT and serum bilirubin were found to increase in the treated group, whereas the values of serum albumin and total protein were found to decrease. Efavirenz is a hepatotoxic drug that should be judiciously used in pregnancy.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"47 5","pages":"489 - 493"},"PeriodicalIF":1.2,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139924977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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An Alternative Technique to Find the Spectrum and Laplacian Spectrum of a Cartesian Product of Signed Graphs 寻找有符号图形笛卡尔积的频谱和拉普拉斯频谱的另一种技术

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-21 DOI: 10.1007/s40009-023-01384-y

Bableen Kaur, Sandeep Kumar, Deepa Sinha

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A Secure Blockchain-Based Access Control Architecture for IoT-Healthcare Applications 基于区块链的物联网-医疗保健应用安全访问控制架构

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-19 DOI: 10.1007/s40009-023-01383-z

Anu Raj, Shiva Prakash

{"title":"A Secure Blockchain-Based Access Control Architecture for IoT-Healthcare Applications","authors":"Anu Raj, Shiva Prakash","doi":"10.1007/s40009-023-01383-z","DOIUrl":"10.1007/s40009-023-01383-z","url":null,"abstract":"<div><p>Nowadays, the demand for the Internet of Medical Things (IoMT) is likely to be driven by the need for real-time health monitoring to handle chronic diseases. Designing a distributed and reliable access control and user authentication scheme for IoMT involves multiple layers of security measures to ensure the integrity, confidentiality, as well as availability of sensitive patient data. However, the major problem with smart healthcare systems is data security and privacy. Blockchain can resolve these issues due to its immutability and transparency features. Most of the existing research enhances security and data privacy but they do not consider the overhead, delay, and scalability. The clustering-based proposed approach adopted the real-world issues of blockchain, i.e., delay, and scalability. It is an efficient access control approach that enables users to establish their desired access control policy to protect their private medical data. It uses a dual chain mechanism in which the access policies are stored in one chain, while the data transactions are stored in another chain. This approach addresses the challenge of access control resolution by enabling data owners to decide their desirable access policies. The experimental results show the efficiency of the proposed scheme in terms of processing time, computational time and its resilience against various security threats.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"47 5","pages":"529 - 537"},"PeriodicalIF":1.2,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139924875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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New Distributional Record of Rhinoceros Leatherjacket, Pseudalutarius nasicornis (Teminck Schlegel, 1850) (Tetraodontiformes: Monacanthidae) From Arabian Coast 阿拉伯海岸犀牛皮甲 Pseudalutarius nasicornis (Teminck Schlegel, 1850) (Tetraodontiformes: Monacanthidae) 的新分布记录

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-16 DOI: 10.1007/s40009-023-01389-7

K. Karuppasamy, B. Sureandiran, V. Vidhya, P. Jawahar

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A New Record of Soft Coral, Lobophytum varium Tixier-Durivault, 1970 (Sarcophytidae: Malacalcyonacea) from the Andaman Islands, India 印度安达曼群岛新记录的软珊瑚 Lobophytum varium Tixier-Durivault, 1970 (Sarcophytidae: Malacalcyonacea)

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-05 DOI: 10.1007/s40009-023-01378-w

S. Rajendra, C. Raghunathan

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Age-Stage, Two-Sex Life Table of the Mustard Aphid, Lipaphis erysimi (Kaltenbach) on Cabbage and Cauliflower under Laboratory and Field Conditions 实验室和田间条件下芥菜蚜 Lipaphis erysimi (Kaltenbach) 在卷心菜和花椰菜上的分龄两性生命表

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-05 DOI: 10.1007/s40009-023-01388-8

M. C. Keerthi, Sachin S. Suroshe

{"title":"Age-Stage, Two-Sex Life Table of the Mustard Aphid, Lipaphis erysimi (Kaltenbach) on Cabbage and Cauliflower under Laboratory and Field Conditions","authors":"M. C. Keerthi, Sachin S. Suroshe","doi":"10.1007/s40009-023-01388-8","DOIUrl":"10.1007/s40009-023-01388-8","url":null,"abstract":"<div><p>Mustard aphid, vernacularly known as turnip aphid, <i>Lipaphis erysimi</i>, is a serious pest of vegetable Brassicas in India. Design of new pest management strategies depends on the life-table parameters. However, life table of <i>L. erysimi</i> was poorly studied under field conditions. The present study aims at constructing life tables of <i>L. erysimi</i> on cabbage and cauliflower under field conditions. The field population had the shortest nymphal duration, viz. 4.31 ± 0.48 and 4.33 ± 0.62 days on cauliflower and cabbage, respectively. The biotic potential of aphid on cauliflower and cabbage in the field was 2.71 × 10<sup>53</sup> and 3.49 × 10<sup>49</sup>, which was much better than the corresponding values in the laboratory (2.86 × 10<sup>38</sup> and 2.27 × 10<sup>38</sup>). The population parameters varied between two rearing conditions, viz. <i>r</i> and <i>λ</i>, was significantly superior under field conditions; however, the <i>R</i><sub>0</sub>, GRR and <i>T</i> were superior under laboratory conditions. On cauliflower and cabbage, the population of <i>L. erysimi</i> doubles in 1.75 and 1.74 days, respectively, whereas in a laboratory conditions, it took 2.24 and 2.47 days. <i>S</i><sub><i>xj</i></sub> of <i>L. erysimi</i> varied across developmental stages. The expected longevity of <i>L. erysimi</i> on cauliflower at age zero (<i>e</i><sub>0</sub>) was 12.84 and 7.90 days under laboratory and field conditions, respectively.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"47 5","pages":"471 - 476"},"PeriodicalIF":1.2,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139764920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Hard Turning of AISI D4 Steel Under Dry Machining and Gas Cooling Attempt is made for the Elimination of White Layer Also Enhancement of Surface Finish 在干式加工和气体冷却条件下硬车削 AISI D4 钢，尝试消除白层并提高表面光洁度

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-04 DOI: 10.1007/s40009-023-01385-x

S. Girisankar, S. Senthil Murugan, S. P. Srinivasan, E. Shankar, A. Rajkumar

{"title":"Hard Turning of AISI D4 Steel Under Dry Machining and Gas Cooling Attempt is made for the Elimination of White Layer Also Enhancement of Surface Finish","authors":"S. Girisankar, S. Senthil Murugan, S. P. Srinivasan, E. Shankar, A. Rajkumar","doi":"10.1007/s40009-023-01385-x","DOIUrl":"10.1007/s40009-023-01385-x","url":null,"abstract":"<div><p>Of late, hard turning is widely accepted as an innovative and cost-effective machining solution for the hard-to-cut materials in a single machining set-up using Dry machining and other cooling medium such as liquid and solid lubricants. The hard turning provides better part quality than grinding, but hard turning surfaces are affected by the distressed surface pattern termed as white layer (WL). This WL is detrimental to the part produced by decreasing the fatigue life. Also, the surface integrity is deteriorated due to dynamic phase transformations. So, an attempt was made with super hardened AISI D4 steel turned with cubic boron nitride insert under Dry Machining, also gas mixture cooling. Noticeably, the results revealed that the dry machining didn’t eliminate WL and produced more roughness. But WL elimination and better surface finish were accomplished under Gas mixture cooling.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><img></picture></div></div></figure></div></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"47 5","pages":"539 - 546"},"PeriodicalIF":1.2,"publicationDate":"2024-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139688840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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First Photographic Record of Indian Skimmer (Rynchops Albicollis) From Uttarakhand, Western Himalayas, India 印度西喜马拉雅山脉北阿坎德邦的印度鳐鱼（Rynchops Albicollis）首次摄影记录

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-02-01 DOI: 10.1007/s40009-023-01390-0

Ashish Kumar Arya, Dinesh Bhatt, Archana Bachheti, Kamal Kant Joshi

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A Multicentric Case–Control Study for Diagnostic Utility of Non-contact Infrared Thermography (IRT) in Type 2 Diabetes 非接触式红外热成像 (IRT) 对 2 型糖尿病诊断效用的多中心病例对照研究

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-01-30 DOI: 10.1007/s40009-023-01381-1

Sanjeev Sinha, Anuj Ajayababu, Renuka Titiyal, Sushil Gupta, Hemant Bhargav, Sandeep Kumar, Kunal Sharma, Shivam Pandey, Ravinder Goswami

{"title":"A Multicentric Case–Control Study for Diagnostic Utility of Non-contact Infrared Thermography (IRT) in Type 2 Diabetes","authors":"Sanjeev Sinha, Anuj Ajayababu, Renuka Titiyal, Sushil Gupta, Hemant Bhargav, Sandeep Kumar, Kunal Sharma, Shivam Pandey, Ravinder Goswami","doi":"10.1007/s40009-023-01381-1","DOIUrl":"10.1007/s40009-023-01381-1","url":null,"abstract":"<div><p>While there is a renewed interest in the use of infrared imaging in the medical field owing to improvements in image acquisition and processing technologies, its utility in the diagnosis of diabetes mellitus on a large scale has not been adequately evaluated in previous studies. This was a multicenter, double-blind case–control trial across three centers in India which enrolled a total of 1095 adults in two groups—590 participants with diabetes and 505 healthy controls. The primary outcome was the difference in thermography readings between the two groups. The secondary outcomes included the correlation of thermography readings with HbA1C, considered the gold standard. The thermography readings at all seven sites were lower in people with diabetes as compared to the control group. However, this attained statistical significance across four sites—forehead (Δmean difference = 0·34, 95% CI [0·14–0·53], medial canthus of both eyes (Δmean difference = 0·48, 95% CI [0·31–0·66], pinna of both ears (Δmean difference = 0·53, 95% CI [0·28–0·73]) and palmar surface of both hands (Δmean difference = 0·28, 95% CI [0·02–0·53]). In addition, thermography readings showed a significant negative correlation with HbA1C values across these four sites, although the strength of the correlation was weak. This study sheds light on the utility of thermography for large-scale noninvasive diagnosis of diabetes mellitus. Future research should focus on large-scale community screening of early asymptomatic disease as well as micro- and macrovascular complications to define its exact role in the overall disease management pathway.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"47 5","pages":"561 - 569"},"PeriodicalIF":1.2,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139645176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-objective Parameter Optimization of Four-Stroke Diesel Engine with Waste Cooking Oil Biodiesel and Diesel Blend using RSM-NSGA-II 利用 RSM-NSGA-II 对使用废食用油生物柴油和柴油混合燃料的四冲程柴油发动机进行多目标参数优化

IF 1.2 4区综合性期刊

National Academy Science Letters Pub Date : 2024-01-29 DOI: 10.1007/s40009-023-01376-y

Pardeep Kumar, Ashwani Kumar Dhingra, Deepak Chhabra, Ashish Chhikara

{"title":"Multi-objective Parameter Optimization of Four-Stroke Diesel Engine with Waste Cooking Oil Biodiesel and Diesel Blend using RSM-NSGA-II","authors":"Pardeep Kumar, Ashwani Kumar Dhingra, Deepak Chhabra, Ashish Chhikara","doi":"10.1007/s40009-023-01376-y","DOIUrl":"10.1007/s40009-023-01376-y","url":null,"abstract":"<div><p>In the last few decades, there has been sharp increase in consumption of energy around the globe. Due to finite sources of fossil fuels and rise in exhaust emissions resulting into global warming, the researchers have shifted to the petroleum fuel alternatives. The present work considers the different engine input factors (i.e., blending ratio and load) while evaluating the different performance parameters (brake thermal efficiency), combustion (brake-specific fuel consumption), and emission parameters (nitrogen oxide, carbon monoxide, and hydrocarbon) while using waste cooking oil biodiesel in a four-stroke single-cylinder diesel engine. A hybrid RSM coupled with NSGA-II technique has been considered for optimizing the performance, combustion, and emission characteristics. The novelty of this work is the application of NSGA II, which has been successfully applied in the simultaneous optimization of brake-specific fuel consumption, brake thermal efficiency, and different emission parameters, viz. carbon monoxide, nitrogen oxide, and hydrocarbon. Five optimum combinations have been evaluated from the 39 Pareto solutions set, and their confirmation tests have also been conducted. From the analysis, the brake thermal efficiency of 31.29% and brake-specific fuel consumption of 0.261 kg/kW-hr along with values of the emissions such as nitrogen oxide: 63.470 ppm, carbon monoxide: 0.085% and hydrocarbons: 20.724 ppm have been achieved. The results are very much within the acceptable limits which confirms the feasibility for the use of waste cooking oil biodiesel in the four-stroke diesel engine.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"47 5","pages":"515 - 520"},"PeriodicalIF":1.2,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139578583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0