Actas dermo-sifiliograficas最新文献

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Updated Perspective from the Spanish Psoriasis Working Group (GPS) on Biosimilar Drug Use in Moderate-to-Severe Psoriasis.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2024.10.066
L Salgado-Boquete, L Puig, J M Carrascosa, P de la Cueva, A López Ferrer
{"title":"Updated Perspective from the Spanish Psoriasis Working Group (GPS) on Biosimilar Drug Use in Moderate-to-Severe Psoriasis.","authors":"L Salgado-Boquete, L Puig, J M Carrascosa, P de la Cueva, A López Ferrer","doi":"10.1016/j.ad.2024.10.066","DOIUrl":"10.1016/j.ad.2024.10.066","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translated article] Multicenter, Prospective, Case-Control Study of Exposome in Melanoma.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.03.008
A Navarro-Bielsa, T Gracia-Cazaña, M Almagro, S De-la-Fuente-Meira, Á Florez, O Yélamos, T Montero-Vilchez, C González-Cruz, A Diago, I Abadías-Granado, V Fuentelsaz, M Colmenero, J Bañuls, S Arias-Santiago, A Buendía-Eisman, M Almenara-Blasco, P Gil-Pallares, Y Gilaberte
{"title":"[Translated article] Multicenter, Prospective, Case-Control Study of Exposome in Melanoma.","authors":"A Navarro-Bielsa, T Gracia-Cazaña, M Almagro, S De-la-Fuente-Meira, Á Florez, O Yélamos, T Montero-Vilchez, C González-Cruz, A Diago, I Abadías-Granado, V Fuentelsaz, M Colmenero, J Bañuls, S Arias-Santiago, A Buendía-Eisman, M Almenara-Blasco, P Gil-Pallares, Y Gilaberte","doi":"10.1016/j.ad.2025.03.008","DOIUrl":"10.1016/j.ad.2025.03.008","url":null,"abstract":"<p><p>UV radiation is the main etiological agent of skin cancer. Other factors such as pollution, diet and lifestyle are also contributing factors. Our aim was to investigate the association between melanoma and exposome factors in the Spanish population with a prospective multicenter case-control study. Case group included patients with melanoma while the control group included people who attended the consultations as companions without a past medical history of skin cancer. A total of 73 melanoma patients and 126 controls were included. The former group included more outdoor workers, a history of skin cancer, drug use (acetylsalicylic acid, antidepressants and ACE inhibitors, p<0.05), more sun exposure (p<0.001) and more sunburns (p=0.04). Controls used shade (p=0.04) or clothing (p<0.001) and the sun protection factor (SPF) used 15 years earlier was higher (p=0.04). Melanoma-related exposome factors are associated with sun exposure, drug intake and food. Prevention strategies should target specific populations, such as outdoor workers by promoting sun-safe behaviors and healthy lifestyle habits since childhood.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ICTIOSIS: Actualización clínica y molecular. Parte 2: ictiosis sindrómicas. Abordaje diagnóstico y terapéutico de las ictiosis.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.03.013
C Gutiérrez-Cerrajero, R González Sarmiento, Á Hernández Martín
{"title":"ICTIOSIS: Actualización clínica y molecular. Parte 2: ictiosis sindrómicas. Abordaje diagnóstico y terapéutico de las ictiosis.","authors":"C Gutiérrez-Cerrajero, R González Sarmiento, Á Hernández Martín","doi":"10.1016/j.ad.2025.03.013","DOIUrl":"https://doi.org/10.1016/j.ad.2025.03.013","url":null,"abstract":"<p><p>Syndromic ichthyoses are a group of disorders whose genetic alterations impact both epidermal and non-epidermal tissues. Therefore, patients present symptoms in other organs. Most are extraordinary and, in some, ichthyosiform desquamation has been poorly described. Their patterns of inheritance are diverse; their extracutaneous clinical signs, heterogeneous; and the skin symptoms, highly variable, which hinders a proper clinical classification.Ichthyosis diagnosis starts with proper anamnesis, detailed physical examination, and detection of associated analytic and/or histologic findings. Genetic testing is indispensable, not only for diagnostic certainty, but also because understanding the molecular substrate for each patient is the first step towards finding an individualized therapeutic regimen. While it will almost invariably involve facilitating desquamation and maintaining skin hydration using topical exfoliants and emollients, recently, replacement therapies aiming at substituting the proteins and lipids specifically altered in each patient are being developed and gene therapy approaches with the ultimate goal of curing the disease are being assessed. In part 2 of this review, we'll be updating the clinical and genetic findings of syndromic entities, ichthyosis diagnosis and treatment.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Seton Placement on Fistula Treatment in Hidradenitis Suppurativa: A Before-and-After Analysis.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.01.007
N Aranda Sánchez, A I Sánchez Moya, E Molina Figuera, A B Gargallo Quintero
{"title":"Impact of Seton Placement on Fistula Treatment in Hidradenitis Suppurativa: A Before-and-After Analysis.","authors":"N Aranda Sánchez, A I Sánchez Moya, E Molina Figuera, A B Gargallo Quintero","doi":"10.1016/j.ad.2025.01.007","DOIUrl":"10.1016/j.ad.2025.01.007","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FR - Metformina en el tratamiento de la hidradenitis supurativa.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.03.005
J M Camino Salvador, A Martínez Fernández, C Chiloeches Fernández
{"title":"FR - Metformina en el tratamiento de la hidradenitis supurativa.","authors":"J M Camino Salvador, A Martínez Fernández, C Chiloeches Fernández","doi":"10.1016/j.ad.2025.03.005","DOIUrl":"https://doi.org/10.1016/j.ad.2025.03.005","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translated article] Ultrasound Features of Primary Cutaneous Marginal Zone B-Cell Lymphoma. 原发性皮肤边缘区B淋巴细胞淋巴瘤的超声特征。
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.03.001
R F Rubio-Aguilera, H Álvarez-Garrido, G Baeza-Hernández, L Fernández-de la Fuente, S P Herrero-Ruiz, B Echeverría-García
{"title":"[Translated article] Ultrasound Features of Primary Cutaneous Marginal Zone B-Cell Lymphoma.","authors":"R F Rubio-Aguilera, H Álvarez-Garrido, G Baeza-Hernández, L Fernández-de la Fuente, S P Herrero-Ruiz, B Echeverría-García","doi":"10.1016/j.ad.2025.03.001","DOIUrl":"10.1016/j.ad.2025.03.001","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview of Actinic Keratoses: Understanding Etiology, Diagnosis, and Treatment Approaches.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.02.024
J Cañueto, L Turrión, C Ferrándiz-Pulido
{"title":"An Overview of Actinic Keratoses: Understanding Etiology, Diagnosis, and Treatment Approaches.","authors":"J Cañueto, L Turrión, C Ferrándiz-Pulido","doi":"10.1016/j.ad.2025.02.024","DOIUrl":"10.1016/j.ad.2025.02.024","url":null,"abstract":"<p><p>Actinic keratoses (AK) are common cutaneous lesions located in skin areas chronically exposed to UV radiation, with the potential of progressing into invasive squamous cell carcinoma (SCC). Since it is not possible to predict which AK lesions will become SCC or when will that happen, treating all AK is generally recommended. There is a wide range of therapies available for AK and new drug approvals have joined the therapeutic armamentarium in recent years. These changes in the available treatments for AK require a review of the scientific evidence available and the current status of AK diagnosis and management in Spain.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Placa blanquecina en la cara anterior del muslo.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.03.011
I R Camardella, M V Marina, S Rodriguez Saa
{"title":"Placa blanquecina en la cara anterior del muslo.","authors":"I R Camardella, M V Marina, S Rodriguez Saa","doi":"10.1016/j.ad.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.ad.2025.03.011","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AEDV BIOBADADERM Registry: 15 Year-Contribution to Psoriasis Therapy Safety.
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2024.11.027
D P Ruiz-Genao, A González-Quesada, A Sahuquillo-Torralba, R Rivera-Díaz, M A Descalzo, I García-Doval
{"title":"AEDV BIOBADADERM Registry: 15 Year-Contribution to Psoriasis Therapy Safety.","authors":"D P Ruiz-Genao, A González-Quesada, A Sahuquillo-Torralba, R Rivera-Díaz, M A Descalzo, I García-Doval","doi":"10.1016/j.ad.2024.11.027","DOIUrl":"10.1016/j.ad.2024.11.027","url":null,"abstract":"<p><p>The objective of this article is to collect and describe the most relevant BIOBADADERM findings since its beginning in 2008. BIOBADADERM is a prospective cohort registry whose main aim is to analyze the safety profile of the new systemic therapy for the management of psoriasis. Data included in the registry allowed the publication of numerous articles over the past 15 years (2008-2023). Data from the registry join those obtained from clinical trials regarding safety and efficacy profile. Additionally, it has expanded our knowledge of population groups excluded from clinical trials and in less frequent settings. Collaboration with other registries has given us a few fact-checking answers in smaller groups.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translated article] Triglyceride-glucose Index as a Predictor of Cardiovascular Events in Psoriatic Patients on Systemic Therapy: A 150-patient Observational Study. 作为银屑病患者心血管事件预测指标的甘油三酯-葡萄糖比值与系统治疗:一项针对 150 名患者的观察性研究。
IF 3.8
Actas dermo-sifiliograficas Pub Date : 2025-03-11 DOI: 10.1016/j.ad.2025.03.007
L Fernández Domper, J M Martin Hernández, J A Páramo, L Fernández Alonso, Á Revert Fernández, M Morales Suarez-Varela
{"title":"[Translated article] Triglyceride-glucose Index as a Predictor of Cardiovascular Events in Psoriatic Patients on Systemic Therapy: A 150-patient Observational Study.","authors":"L Fernández Domper, J M Martin Hernández, J A Páramo, L Fernández Alonso, Á Revert Fernández, M Morales Suarez-Varela","doi":"10.1016/j.ad.2025.03.007","DOIUrl":"10.1016/j.ad.2025.03.007","url":null,"abstract":"<p><p>Psoriasis is consistently associated with an elevated cardiovascular risk. However, biochemical parameters are needed to predict cardiovascular events in these patients. Therefore, we conducted a retrospective cohort study with psoriatic patients undergoing systemic treatment to analyze the value of the triglyceride-glucose (TyG) index in predicting the development of major adverse cardiovascular events (MACE). A total of 150 patients were selected, 12 of whom developed MACE (11 myocardial infarctions and one stroke) after a median follow-up of 17 months. The highest quartile of the TyG index was associated with a greater risk of developing MACE (HR, 9.3; 95%CI, 1.1-78.9). The predictive capabilities of the TyG index for predicting these events showed an area under the curve of 0.75 (0.60-0.90), p=0.001. These results demonstrate that the TyG index could be useful in the early identification of psoriatic patients at high risk of developing MACE.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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