M. Mansilla-Polo , J. López-Davia , D. Morgado-Carrasco
{"title":"[Translated article] Mucocutaneous Alterations After Hematopoietic Stem Cell Transplantation: Literature Update and Review","authors":"M. Mansilla-Polo , J. López-Davia , D. Morgado-Carrasco","doi":"10.1016/j.ad.2025.06.006","DOIUrl":"10.1016/j.ad.2025.06.006","url":null,"abstract":"<div><div>In recent years, hematopoietic stem cell transplantation (HSCT) has revolutionized the treatment of various hematological and non-hematological diseases. Its implementation is not stranger to risks and involves a significant rate of complications, including mucocutaneous adverse events. We present a narrative review of the mucocutaneous alterations observed after HSCT. Among these, acute and chronic graft-versus-host disease (GVHD) stand out, whose diagnosis and treatment can be challenging. Other common conditions include cutaneous adverse reactions and infections with mucocutaneous involvement. Additionally, various studies indicate that these individuals may have a higher rate of mucocutaneous neoplasms. Early identification and management of these complications, along with a multidisciplinary approach, are essential to improving these patients’ quality of life and long-term outcomes. Furthermore, it is advisable to screen for skin cancer in these individuals, especially if they have other associated risk factors.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 8","pages":"Pages T876-T891"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G.G. Dradi, E. Gómez de la Fuente, E. García Zamora
{"title":"Lesiones ampollosas tras artroplastia de rodilla","authors":"G.G. Dradi, E. Gómez de la Fuente, E. García Zamora","doi":"10.1016/j.ad.2023.11.024","DOIUrl":"10.1016/j.ad.2023.11.024","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 8","pages":"Pages 908-910"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Fernández-de-Misa , M. Montes-de-Oca , I. Loizate , N. Hernández-Hernández
{"title":"[Translated article] Multiple Basal Cell Carcinomas. Timeline and Underlying Risk Factors","authors":"R. Fernández-de-Misa , M. Montes-de-Oca , I. Loizate , N. Hernández-Hernández","doi":"10.1016/j.ad.2025.06.011","DOIUrl":"10.1016/j.ad.2025.06.011","url":null,"abstract":"<div><h3>Introduction</h3><div>Between 29% and 53% of the patients who develop basal cell carcinoma (BCC) will develop new BCCs.</div></div><div><h3>Objectives</h3><div>Current objectives are to analyze the proportion and basic characteristics of patients who develop BCC >1, to delineate the concept of multiple BCC (mBCC) and be able to identify the factors associated with its development, and analyze its timeframe.</div></div><div><h3>Patients and method</h3><div>We conducted a retrospective observational study including all patients diagnosed with sporadic BCC from January 1st, 2014 through December 31st, 2014 at a tertiary referral center. Data included dates of BCCs, gender, age and histology of the first BCC, and the presence of BCC >1 at the initial appointment (cluster<sup>+</sup>). mBCC was defined as a patient who developed a series of BCCs >the 75th percentile of the series.</div></div><div><h3>Results</h3><div>A total of 758 patients (51.2% men), were included. After a median follow-up of 100 months, 52.8% of the patients developed BCC >1. The 75th percentile of the number of BCCs was 3. Factors associated to mBCCs included being cluster<sup>+</sup> (OR, 5.6; 95%<span>C</span>I, 3.2–9.7), being men (OR, 3.1; 95%CI, 2.0–4.8) and diagnosed with the first BCC between ages of 50 and 80 years (OR, 2.1; 95%CI, 1.3–3.5). After 5 years, 54% of patients exhibiting these three factors developed mBCC. The estimated median time to mBCC was 38.00 months (95%CI, 0–79.71).</div></div><div><h3>Conclusions</h3><div>A quarter of patients who exhibit 1 BCC eventually develop four or more BCCs. Analyzing routine parameters may help identify individuals at a higher risk of developing mBCC and predict its timeframe.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 8","pages":"Pages T815-T823"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Translated article] New Prevention Measures in Venereology: Evidence Review on the DoxiPrEP/PEP Antibiotic and the 4CMenB Vaccine","authors":"A. Català , J. Riera , I. Fuertes de Vega","doi":"10.1016/j.ad.2025.06.014","DOIUrl":"10.1016/j.ad.2025.06.014","url":null,"abstract":"<div><div>Sexually transmitted infections (STIs) are increasing in Spain. The traditional strategy for STI control is mainly based on screening and treatment of STIs in patients with risky sexual practices. In recent years, new interesting primary and secondary prevention strategies are being studied to reduce the incidence rate of STIs in high-risk populations. The most interesting one, based on the evidence obtained, is the use of doxycycline and meningococcal B vaccines. Specialists in dermatology and venereology must be informed about these new developments that may have an impact on the way in which STIs are managed worldwide. This is a scientific evidence review of these new interesting primary and secondary prevention strategies to control STIs in a high-risk population.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 8","pages":"Pages T849-T862"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Baselga , J. Bernabeu-Wittel , I. Betlloch Mas , M. Campos Domínguez , A. Carrasco Sanz , J. del Boz , R. de Lucas Laguna , J. del Pozo Losada , A. Hernández Martín , L. Jiménez Montañés , J.C. López Gutiérrez , A. Martín-Santiago , P. Redondo , A. Torrelo Fernández , A. Vicente Villa
{"title":"[Translated article] Update of the Spanish Consensus Document on Infantile Hemangioma","authors":"E. Baselga , J. Bernabeu-Wittel , I. Betlloch Mas , M. Campos Domínguez , A. Carrasco Sanz , J. del Boz , R. de Lucas Laguna , J. del Pozo Losada , A. Hernández Martín , L. Jiménez Montañés , J.C. López Gutiérrez , A. Martín-Santiago , P. Redondo , A. Torrelo Fernández , A. Vicente Villa","doi":"10.1016/j.ad.2025.06.017","DOIUrl":"10.1016/j.ad.2025.06.017","url":null,"abstract":"<div><div>This document updates the 2016 Spanish consensus on infantile hemangioma (IH) based on the currently existing scientific medical literature and the experience of a panel of experts. IH is the most frequent pediatric vascular tumor, is often diagnosed clinically, and usually resolves spontaneously. However, in 10–15% of cases it results in severe complications. Data show that early intervention and long-term treatment improves outcomes, underscoring the need for clear clinical practice guidelines on the management of patients with IH. This update highlights the usefulness of the IHReS scale for IH patient referral, the importance of telemedicine implementation for IH patient care, the safety of beta-blocker therapy, and the extension of propranolol regimens up to 24<!--> <!-->months.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 8","pages":"Pages T837-T848"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Muntaner-Virgili, C. Torrecilla-Vall-llossera, M. Bonfill-Ortí, I. Figueras-Nart
{"title":"Effectiveness and safety in the use of Janus kinase inhibitors in combination with other classic or biological systemic treatments: real-world clinical practice experience","authors":"C. Muntaner-Virgili, C. Torrecilla-Vall-llossera, M. Bonfill-Ortí, I. Figueras-Nart","doi":"10.1016/j.ad.2025.02.025","DOIUrl":"10.1016/j.ad.2025.02.025","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 8","pages":"Pages 927-931"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}