Acta physiologica Hungarica最新文献_第4页

Third Congress of Physiological Sciences of Serbia with international participation (October 29-31, 2014, Belgrade, Serbia) (Report). 第三届国际参加的塞尔维亚生理科学大会(2014年10月29-31日，塞尔维亚贝尔格莱德)(报告)。

Acta physiologica Hungarica Pub Date : 2015-06-01 DOI: 10.1556/036.102.2015.2.1

Dragan M Djuric

引用次数: 0

Prevalence of physiological and pathological electrocardiographic findings in Hungarian athletes. 匈牙利运动员的生理和病理心电图发现的普遍性。

Acta physiologica Hungarica Pub Date : 2015-06-01 DOI: 10.1556/036.102.2015.2.13

Orsolya Kiss, Nóra Sydó, P Vargha, E Édes, G Merkely, T Sydó, Béla Merkely

{"title":"Prevalence of physiological and pathological electrocardiographic findings in Hungarian athletes.","authors":"Orsolya Kiss, Nóra Sydó, P Vargha, E Édes, G Merkely, T Sydó, Béla Merkely","doi":"10.1556/036.102.2015.2.13","DOIUrl":"https://doi.org/10.1556/036.102.2015.2.13","url":null,"abstract":"Unlabelled: In Hungary, ECG is a keystone of routine athletic screening. Its significance is based on simplicity, quickness and high informative value as well as the fact that appearance of pathological ECG signs can precede the formation of structural heart diseases. During screening of healthy athletes, we studied the incidence of athletic ECG changes and pathological ECG abnormalities.Methods: We performed detailed analysis of 12-lead ECG recordings of asymptomatic elite, non-elite and master athletes and controls.Results: 227 athletes (male: 180, age: 27.2 ± 8.7 years) and 89 controls (male: 57, age: 28.1 ± 6.8 years) were examined. Benign ECG signs: sinus bradycardia, early repolarization and isolated Voltage criteria of left ventricular hypertrophy were common and more often in athletes compared to controls. Potentially pathological ECG signs: ST- (6.6% vs. 1.1%, p < 0.05) and T-wave (15.0% vs. 5.6%, p < 0.05) changes and signs of pathological left ventricular hypertrophy (5.3% vs. 0%, p < 0.05) occurred more frequently in athletes compared to controls.Conclusions: Signs of pathological left ventricular hypertrophy and repolarization abnormalities are more often in athletes. No structural heart disease could be verified in the background of the disorders. However, athletes having pathological ECG should be kept under tight cardiology control. Exact definition and widespread knowledge of pathological ECG changes is essential in early recognition of high risk athletes.","PeriodicalId":7167,"journal":{"name":"Acta physiologica Hungarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/036.102.2015.2.13","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33410687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Organotypic tissue culture investigation of homocysteine thiolactone cardiotoxic effect. 同型半胱氨酸硫内酯心脏毒性作用的器官型组织培养研究。

Acta physiologica Hungarica Pub Date : 2015-06-01 DOI: 10.1556/036.102.2015.2.4

Ekaterina V Lopatina, A V Kipenko, V A Penniyaynen, N A Pasatetskaya, D Djuric, B V Krylov

引用次数: 5

Iron concentrations in atherosclerotic plaque and serum in patients with carotid atherosclerosis. 颈动脉粥样硬化患者动脉粥样硬化斑块和血清中的铁浓度。

Acta physiologica Hungarica Pub Date : 2015-06-01 DOI: 10.1556/036.102.2015.2.5

Nebojsa M Tasic, D Tasic, M Veselinovic, V Jakovljevic, D Djuric, D Radak

{"title":"Iron concentrations in atherosclerotic plaque and serum in patients with carotid atherosclerosis.","authors":"Nebojsa M Tasic, D Tasic, M Veselinovic, V Jakovljevic, D Djuric, D Radak","doi":"10.1556/036.102.2015.2.5","DOIUrl":"https://doi.org/10.1556/036.102.2015.2.5","url":null,"abstract":"The aim of this study was to investigate the iron concentrations in serum and carotid plaque in patients with different morphology of carotid atherosclerotic plaque and compared with other metal ions. Carotid endarterectomy due to the significant atherosclerotic stenosis was performed in 91 patients. Control group consisted of 27 patients, without carotid atherosclerosis. Atherosclerotic plaques were divided into four morphological groups, according to ultrasonic and intraoperative characteristics. Iron, copper and zinc concentration in plaque, carotid artery and serum were measured by spectrophotometry. Serum iron concentrations were higher in patients with hemorrhagic plaques in comparison to the control group (4.7 μmol/l ± 1.2 vs. 2.1 μmol/l ± 0.8, p < 0.05). Iron concentrations were higher in patients with hemorrhagic plaques in comparison to fibrolipid plaques (72.1 ± 14.3 μg/g vs. 39.3 ± 22.9 μg/g; p < 0.05). Negative significant correlation was found for zinc in serum and plaque iron concentration in patients (p < 0.05). We also demonstrated positive significant correlation for copper and iron in serum (p < 0.05). The data obtained in the current study are consistent with the hypothesis that high iron levels may contribute to atherosclerosis and its complications as factors in a multifactorial disease.","PeriodicalId":7167,"journal":{"name":"Acta physiologica Hungarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/036.102.2015.2.5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33411249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Assessment of heat provocation tests on the human gingiva: the effect of periodontal disease and smoking. 热激试验对人牙龈的影响:牙周病和吸烟的影响。

Acta physiologica Hungarica Pub Date : 2015-06-01 DOI: 10.1556/036.102.2015.2.8

E Molnár, Z Lohinai, A Demeter, B Mikecs, Z Tóth, János Vág

{"title":"Assessment of heat provocation tests on the human gingiva: the effect of periodontal disease and smoking.","authors":"E Molnár, Z Lohinai, A Demeter, B Mikecs, Z Tóth, János Vág","doi":"10.1556/036.102.2015.2.8","DOIUrl":"https://doi.org/10.1556/036.102.2015.2.8","url":null,"abstract":"Unlabelled: Periodontal inflammation is associated with morphological changes in the blood vessels which may influence the regulation of gingival blood flow (GBF). Our aim was to adapt the heat provocation test to the human gingiva to assess vascular reactivity in periodontal inflammation.Method: GBF was recorded by Laser Doppler Flowmetry before and after heat provocation in healthy volunteers (n = 50). Heat was generated either by warm saline or a halogen lamp. The latter method was also utilized for a heat test in non-smoking and smoking patients with periodontal inflammation. The circulatory parameters were correlated to the inflammatory marker, i.e. gingival crevicular fluid (GCF) production measured by Periotron.Results: Local application of heat caused a rapid, significant and transient increase in GBF regardless of the method used. The increase in the speed and not in the concentration of moving blood cells was responsible for increased GBF. Higher GCF values were correlated with increased peak flow, flux pulse amplitude and faster restoration of GBF after the test in non-smokers, but not in smokers.Conclusions: The heat test could be a valuable tool to check the vascular reactivity of gingival vessels. Moderate periodontal inflammation may facilitate gingival vascular responsiveness which can be suppressed by smoking.","PeriodicalId":7167,"journal":{"name":"Acta physiologica Hungarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/036.102.2015.2.8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33411252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

The effect of subchronic supplementation with folic acid on homocysteine induced seizures. 亚慢性补充叶酸对同型半胱氨酸诱发癫痫发作的影响。

Acta physiologica Hungarica Pub Date : 2015-06-01 DOI: 10.1556/036.102.2015.2.6

A Rasic-Markovic, B Rankov-Petrovic, D Hrncic, D Krstic, M Colovic, Dj Macut, D Djuric, Olivera Stanojlovic

{"title":"The effect of subchronic supplementation with folic acid on homocysteine induced seizures.","authors":"A Rasic-Markovic, B Rankov-Petrovic, D Hrncic, D Krstic, M Colovic, Dj Macut, D Djuric, Olivera Stanojlovic","doi":"10.1556/036.102.2015.2.6","DOIUrl":"https://doi.org/10.1556/036.102.2015.2.6","url":null,"abstract":"Influence of folic acid on the CNS is still unclear. Folate has a neuroprotective effect, while on the other hand excess folate can exacerbate seizures in epileptics. The aim of the present study was to examine the effect of subchronic administration of folic acid on behavioural and electroencephalographic (EEG) characteristics of DL homocysteine thiolactone induced seizures in adult rats. The activity of Na⁺/K⁺-ATPase and Mg²⁺-ATPase in different brain regions was investigated. Adult male Wistar rats were divided into groups: 1. Controls (C, 0.9% NaCl); 2. DL homocysteine-thiolactone 8.0 mmol/kg (H); 3. Subchronic supplementation with folic acid 5 mg/kg for 7 days (F) and 4. Subchronic supplementation with F + single dose of H (FH). Seizure behaviour was assessed by incidence, latency, number and intensity of seizure episodes. Seizure severity was described by a descriptive scale with grades 0-4. For EEG recordings, three gold-plated recording electrodes were implanted into the skull. Subchronic supplementation with folic acid did not affect seizure incidence, median number of seizure episodes and severity in FH, comparison with H (p > 0.05). The majority of seizure episodes in all groups were of grade 2. There were no significant differences in lethal outcomes at 24 h upon H injection in the FH vs. H group. The activity of Na⁺/K⁺-ATPase and Mg²⁺-ATPase was significantly increased in almost all examined structures in the FH vs. H group. Subchronic folic acid administration did not exacerbate H induced seizures and completely recovered the activity of ATPases.","PeriodicalId":7167,"journal":{"name":"Acta physiologica Hungarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/036.102.2015.2.6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33411250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Application of atomic force microscopy for investigation of Na(+),K(+)-ATPase signal-transducing function. 应用原子力显微镜研究Na(+)、K(+)- atp酶的信号转导功能。

Acta physiologica Hungarica Pub Date : 2015-06-01 DOI: 10.1556/036.102.2015.2.2

M M Khalisov, A V Ankudinov, V A Penniyaynen, D Dobrota, Boris V Krylov

引用次数: 4

Preliminary study of haplotypes linked to the rare cystic fibrosis E1104X mutation. 与罕见囊性纤维化E1104X突变相关的单倍型的初步研究。

Acta physiologica Hungarica Pub Date : 2015-03-01 DOI: 10.1556/APhysiol.101.2014.013

S Oueslati, S Hadj Fredj, R Belhaj, H Siala, A Bibi, Taieb Messaoud

{"title":"Preliminary study of haplotypes linked to the rare cystic fibrosis E1104X mutation.","authors":"S Oueslati, S Hadj Fredj, R Belhaj, H Siala, A Bibi, Taieb Messaoud","doi":"10.1556/APhysiol.101.2014.013","DOIUrl":"https://doi.org/10.1556/APhysiol.101.2014.013","url":null,"abstract":"The analysis of some extra- and intragenic markers within or closely linked to the cystic fibrosis transmembrane regulator (CFTR) gene is useful as a molecular method in clinical linkage analysis. Indeed, knowing that the molecular basis of cystic fibrosis (CF) is highly heterogeneous in our population, the study of haplotype association with normal and CF chromosomes could be very helpful in cases where one or both mutations remain unidentified. In this study, we analysed with PCR-RFLP and capillary electrophoresis some extra (pJ3.11, KM19 and XV2C) and intragenic (IVS8CA, IVS17bTA and IVS17bCA) polymorphic markers in 50 normal and 10 Tunisian patients carrying the rare E1104X mutation in order to determine the haplotype associated with this mutation. For the extragenic markers, 8 haplotypes were identified. The most frequent of them are the 221 and 112 accounting for 80% of total haplotypes. For the intragenic markers, five haplotypes were present on the E1104X chromosomes. One of them 16-31-13 accounted for 50%. To our knowledge, this is the first work to be interested to the haplotypes linked to the E1104X mutation. This preliminary study of haplotypes could be a helpful method to determine the molecular lesions responsible of this pathology. ","PeriodicalId":7167,"journal":{"name":"Acta physiologica Hungarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/APhysiol.101.2014.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32886096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Quality of functional movement patterns and injury examination in elite-level male professional football players. 优秀男子职业足球运动员功能运动模式质量及损伤检查。

Acta physiologica Hungarica Pub Date : 2015-03-01 DOI: 10.1556/APhysiol.101.2014.010

David Zalai, G Panics, P Bobak, I Csáki, P Hamar

{"title":"Quality of functional movement patterns and injury examination in elite-level male professional football players.","authors":"David Zalai, G Panics, P Bobak, I Csáki, P Hamar","doi":"10.1556/APhysiol.101.2014.010","DOIUrl":"https://doi.org/10.1556/APhysiol.101.2014.010","url":null,"abstract":"The purpose of this study is to examine the quality of functional movement patterns among one of Hungary's first league soccer clubs, where the elite male football players (N = 20) utilize the well-established Functional Movement Screen™ (FMS) system; a comprehensive functional program designed to determine and identify the quality of movement and the greatest risk factors for non-contact injuries. Furthermore, an additional purpose of this program is to examine injuries over the course of 6 competitive months. Focusing on the mechanisms of injuries and their causes in the lower extremities during this period is one of the key objectives. Over the course of 6 months we found significant differences between ankle injuries and the FMS Hurdle Step exercise (p < 0.05), and the FMS Deep Squat exercise and knee and hip injuries (p < 0.05). The FMS pre-screening system found lower limb asymmetry present in 40% of the participants. The authors believe that the importance of preventative measures and structural sport specific pre-screening cannot be overemphasized, and that there is a growing need for further transparent research in this field in order to be more effective with regard to programs dedicated to injury prevention and the enhancement players' physical performance. ","PeriodicalId":7167,"journal":{"name":"Acta physiologica Hungarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1556/APhysiol.101.2014.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32886098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 43

Pre- and post-estrogen administration in global cerebral ischemia reduces blood-brain barrier breakdown in ovariectomized rats. 全脑缺血前后雌激素给药可减少去卵巢大鼠血脑屏障的破坏。

Acta physiologica Hungarica Pub Date : 2015-03-01 DOI: 10.1556/APhysiol.102.2015.1.6

G Uzum, N Bahçekapılı, A K Baltaci, Rasim Mogulkoc, Y Z Ziylan

{"title":"Pre- and post-estrogen administration in global cerebral ischemia reduces blood-brain barrier breakdown in ovariectomized rats.","authors":"G Uzum, N Bahçekapılı, A K Baltaci, Rasim Mogulkoc, Y Z Ziylan","doi":"10.1556/APhysiol.102.2015.1.6","DOIUrl":"https://doi.org/10.1556/APhysiol.102.2015.1.6","url":null,"abstract":"The aim of present study was to determine the effect of estrogen treatment on blood-brain barrier permeability in rats with induced global cerebral ischemia. The study included six-month-old female Sprague-Dawley rats which were divided into the following groups: Control-Ischemia-Reperfusion (C + I-R); Ovariectomy-Ischemia-Reperfusion (Ovx + I-R); Ovariectomy + Estrogen + Ischemia-Reperfusion (Ovx + E + I-R); Ovariectomy + Ischemia-Reperfusion + Estrogen (Ovx + I-R + E). Ischemia-reperfusion was induced by clamping two carotid arteries, then opening the clamp. Blood-brain barrier permeability was visualized by Evans Blue extravasation and quantified by spectrophotometry. Our results indicate that following ischemia-reperfusion the BBB permeability is increased in ovariectomized rats (Evans Blue extravasation) compared to the control group in the cortex, thalamus, hippocampus, cerebellum and brain stem, while in the midbrain no significant increase was detected. In contrast, BBB permeability in the groups treated with estrogen, administered either before or after ischemia-reperfusion, was significantly lower than in ovariectomized animals. In conclusion, the increase in BBB permeability resulting from experimentally induced cerebral ischemia was prevented by exogenous estrogen treatment. The study results indicate that estrogen may be used for therapeutic purposes in ischemia-reperfusion. ","PeriodicalId":7167,"journal":{"name":"Acta physiologica Hungarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33158396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5