3 Biotech最新文献

{"title":"Cutting-edge perspectives on biosurfactants: implications for antimicrobial and biomedical applications.","authors":"Kashish Gupta, Varun Kumar Sharma","doi":"10.1007/s13205-024-04146-9","DOIUrl":"10.1007/s13205-024-04146-9","url":null,"abstract":"<p><p>Biosurfactants, naturally produced by plants and microorganisms, closely mimic synthetic surfactants in physiochemical properties, making them valuable alternatives in various applications. They serve as antimicrobial agents and play a crucial role in immune regulations. These compounds find wide use in industries like food processing, biodegradation, pharmaceuticals, and naturally present in the skin, brain, lungs, and gut, maintaining membrane permeability for organ health. This review outlines the basic characteristics and classes of biosurfactants (glycolipids, lipopeptides, phospholipids, and glycoproteins) and explores their biomedical importance, emphasizing their anti-adhesive, antimicrobial, and immune-modulating properties. This review aimed to provide outline the fundamental characteristics of biosurfactants and deliver a brief overview of their different classes, including glycolipids, lipopeptides, phospholipids, and glycoproteins. Furthermore, this review also explore their biomedical significance, highlighting their anti-adhesive, antimicrobial, and immune-modulating properties.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"297"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultivation of microalgae <i>Chlorella vulgaris</i>, <i>Monoraphidium</i> sp and <i>Scenedesmus obliquus</i> in wastewater from the household appliance industry for bioremediation and biofuel production.","authors":"Kelly Lima de Oliveira, José Lucas da Silva Oliveira, Egídia Andrade Moraes, Kelma Maria Dos Santos Pires Cavalcante, Mona Lisa Moura de Oliveira, Carlúcio Roberto Alves","doi":"10.1007/s13205-024-04142-z","DOIUrl":"https://doi.org/10.1007/s13205-024-04142-z","url":null,"abstract":"<p><p>Microalgae <i>Chlorella vulgaris, Scenedesmus obliquus, and Monoraphidium</i> sp were cultivated in effluent from the household appliance industry as an alternative medium for bioremediation due to the high variability of chemical and biological substances in wastewater. The experiments were carried out using biological effluent (BE), chemical effluent (CE), and a combination of the two (MIX). The results showed a maximum biomass yield of 1056 mg/L (± 0.216) in the BE cultivation of the microalga <i>Scenedesmus obliquus,</i> 969 mg/L (± 0.20) in the BE of the microalga <i>Monoraphidium</i> sp. and 468 mg/L (± 0.46) in the CE of <i>Chlorella vulgaris.</i> In addition, they showed <math><mrow><mi>N</mi> <msubsup><mi>O</mi> <mrow><mn>3</mn></mrow> <mo>-</mo></msubsup> </mrow> </math> removal (100%) in the CE and MIX for cultivation with <i>Chlorella vulgaris</i> and 100% BE and 75% MIX with <i>Monoraphidium</i> sp<i>.</i> For the <math><mrow><mi>P</mi> <msubsup><mi>O</mi> <mrow><mn>3</mn></mrow> <mrow><mn>4</mn> <mo>-</mo></mrow> </msubsup> </mrow> </math> (75.3%, 99% e 97.9%) in the cultures with <i>C. vulgaris</i> BE, CE, and MIX respectively, with <i>Monoraphidium</i> sp. 58% in BE and 42% in CE and MIX. With <i>S. obliquus</i>, 100% removal was observed in all 3 treatments. Metal removal was also observed. The <i>C. vulgaris</i> culture showed lipid contents of 16%, 12%, and 17% for BE, CE, and MIX, respectively. For <i>Monoraphidium</i> sp., 14.5% for BE, 16% for CE, and 14% for MIX. In the culture of <i>S. obliquus,</i> 17%, 15.5%, and 16.5% for BE, CE, and MIX, respectively.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"294"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11550306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antidiabetic, anti-inflammatory, antioxidant, and cytotoxicity potentials of green-synthesized zinc oxide nanoparticles using the aqueous extract of <i>Helichrysum cymosum</i>.","authors":"Achasih Q Nkemzi, Kunle Okaiyeto, Omolola Oyenihi, Chinyerum S Opuwari, Okobi E Ekpo, Oluwafemi O Oguntibeju","doi":"10.1007/s13205-024-04125-0","DOIUrl":"10.1007/s13205-024-04125-0","url":null,"abstract":"<p><p>The current research involved the synthesis of zinc oxide nanoparticles (ZnO-NPs) using an aqueous extract of <i>Helichrysum cymosum</i> shoots, and subsequent characterization via different analytical methods, such as UV-Vis spectroscopy, Scanning electron microscope (SEM), Energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), Transmission electron microscope (TEM), and zeta potential. The biological effects of the ZnO-NPs were then tested against C3A hepatocyte cells and L6 myocyte cell lines via series of analysis, including cytotoxicity, antioxidant, anti-inflammatory, and antidiabetic effect via enzymatic inhibition. The UV-Vis analysis showed a maximum absorption spectrum at 360, and the TEM analysis reveals a spherical and hexagonal structures, with an average dimension of 28.05-58.3 nm, and the XRD reveals a crystalline hexagonal structure. The zeta potential evaluation indicated that the ZnO-NPs are relatively stable at - 20 mV, and the FTIR analysis identified some important functional group associated with phenolics, carboxylic acid, and amides that are responsible for reducing and stabilizing the ZnO-NPs. The synthesized ZnO-NPs demonstrated cytotoxic effects on the cell lines at higher concentrations (125 µg/mL and 250 µg/mL), complicating the interpretation of the results of the inflammatory and antioxidant assays. However, there was a significant (<i>p</i> < 0.05) increase in the inhibitions of pancreatic lipase, alpha-glucosidase, and alpha-amylase, indicating beneficial antidiabetic effects.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"291"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11535088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryopreservation of two-celled pollen: a model system for studying the cellular mechanisms of cryoinjury and recovery.","authors":"Ravi Gowthami, P E Rajasekharan, Subhash Chander, Muthusamy Shankar, Vartika Srivastava, Anuradha Agrawal","doi":"10.1007/s13205-024-04140-1","DOIUrl":"10.1007/s13205-024-04140-1","url":null,"abstract":"<p><p>Cryopreservation serves as an invaluable technique for safeguarding the genetic diversity of plants and various organisms, while also facilitating fundamental biological research. Despite notable advancements in this field, the cryopreservation of certain cell types and tissues remains challenging, particularly those that exhibit sensitivity to low temperatures. Two-celled pollen is a promising model system for the study of cryopreservation. By exploring the cryopreservation of two-celled pollen, deeper insights can be gained into the cellular and molecular mechanisms of cryoinjury and recovery. This knowledge can be used to develop new and improved cryopreservation protocols for a wider range of cell types and tissues. It is relatively simple, consisting of only two cells, and it is relatively easy to cryopreserve and culture. In addition to its potential for improving cryopreservation technologies, the study of two-celled pollen cryopreservation can also shed light on fundamental biological processes such as cell division, development, and stress tolerance. By unlocking the mysteries of two-celled pollen cryopreservation, we can gain a deeper understanding of nature's inner workings. This article reviews examples of studies that have successfully used two-celled pollen cryopreservation, highlighting key findings and discoveries enabled by this technique as case studies.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"304"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Investigating the role of prognostic mitophagy-related genes in non-small cell lung cancer pathogenesis via multiomics and network-based approach.","authors":"Prithvi Singh, Gulnaz Tabassum, Mohammad Masood, Saleha Anwar, Mansoor Ali Syed, Kapil Dev, Md Imtaiyaz Hassan, Mohammad Mahfuzul Haque, Ravins Dohare, Indrakant Kumar Singh","doi":"10.1007/s13205-024-04149-6","DOIUrl":"https://doi.org/10.1007/s13205-024-04149-6","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1007/s13205-024-04127-y.].</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"306"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11579259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142708958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Swimming upregulates APOL3 through regulating macrophage polarization to inhibit glycolysis and the development of melanoma.","authors":"Zhenlei Lyu, Appukutty Mahenderan, Ammu Kutty G K Radhakrishnan, Yit Siew Chin, Chao Yin","doi":"10.1007/s13205-024-04150-z","DOIUrl":"https://doi.org/10.1007/s13205-024-04150-z","url":null,"abstract":"<p><p>This study investigated the role of swimming exercise in regulating melanoma tumour growth and glycolysis in cancer cells, the specific mechanism involved was also studied. In our study, a murine melanoma tumour model was established to assess the impact of swimming on tumour growth. The mRNA and protein expressions were assessed using qRT-PCR, western blot, and IHC. The metabolic behavior of melanoma cells was examined through lactic acid level measurements and glucose consumption assessments. CCK-8 and colony formation assays were used to detect cell viability and proliferation. ELISA was employed to determine the levels of cytokines secreted by macrophages. The interaction between APOL3 and STAT3 was analyzed by dual luciferase reporter gene and ChIP assays. Our results demonstrated that swimming exercise suppressed melanoma growth in mice by suppressing glycolysis, which might be related to APOL3 upregulation. In addition, downregulation of APOL3 in melanoma was associated with poor prognosis, and APOL3 overexpression markedly suppressed melanoma cell proliferation by reducing glucose uptake and lactate production in vitro. Mechanistically, STAT3 directly down-regulated APOL3 transcription. Swimming upregulated APOL3 by inactivating the IL-6R-STAT3 signaling axis in melanoma cells by inhibiting the secretion of IL-6 by M2 macrophages. As expected, IL-6 secreted by M2 macrophages promoted glycolysis in melanoma cells by reducing APOL3 expression. In summary, swimming inactivated the IL-6R/STAT3 signaling axis in melanoma cells by inhibiting the secretion of IL-6 by M2 macrophages, which could suppress the growth of melanoma in the body by upregulating APOL3 to inhibit glycolysis.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"307"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dissecting the genetic diversity of cultivated tomato (<i>Solanum lycopersicum</i>) germplasm resources: a comparison of ddRADseq genotyping and microsatellite analysis via capillary electrophoresis and high-resolution melting.","authors":"Pasquale Tripodi, Rosa D'Alessandro, Annalisa Cocozza, Gabriele Campanelli","doi":"10.1007/s13205-024-04141-0","DOIUrl":"https://doi.org/10.1007/s13205-024-04141-0","url":null,"abstract":"<p><p>Understanding the genetic diversity of crops is of fundamental importance for the efficient use and improvement of germplasm resources. Different molecular genotyping systems have been implemented for population structure and phylogenetic relationships analyses, among which, microsatellites (SSRs) and single nucleotide polymorphisms (SNPs) markers have been the most widely used. This study reports the efficacy of SNPs detected via double-digest restriction-site-associated DNA sequencing (ddRADseq) and SSRs analyzed via capillary electrophoresis (CE) and high-resolution melting (HRM) in tomato. In total, 21,020 high-quality SNPs, 20 CE-SSRs, and 17 HRM-SSR markers were assayed in a panel of 72 accessions that included a diversified set of landraces, long-shelf-life cultivars and heirlooms with different origins and fruit typology. The results showed how the population structure analysis was consistent using the three genotyping methods, although SNPs were more efficient in distinguishing cultivar types and in measuring the degree of accessions' similarity. Compared to CE-SSR, the analysis of microsatellites via HRM yielded a slightly higher number of alleles (98 vs<i>.</i> 96). HRM-SSR demonstrated a distinction between European and non-European germplasm, better resolving the collection's diversity and being more consistent with SNP data. Phylogenetic trees drawn with independent marker data, detected specific groups of accessions showing robust clusters, highlighting how heirlooms were less heterogeneous than landraces. In addition, the fixation index (<i>F</i> _<i>ST</i> ) revealed a high genetic differentiation between heirlooms and long-shelf-life cultivars, with SNP and SSR-HRM data emphasizing the distinction between cherry and plum types and CE-SSR data between cherry and oxheart types. In all instances, a greater molecular variance was found within the different considered biological statuses, provenances, and typologies rather than among them. This work presents the first attempt to compare the three tomato genotyping techniques in tomato. Findings highlighted how the markers used are complementary for genetic diversity analysis, with SNPs providing better insight and HRM-SSR as a viable alternative to capillary electrophoresis to dissect the genetic structure.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13205-024-04141-0.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"296"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11550310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micropropagation and in vitro rejuvenation of <i>Eucalyptus cloeziana</i> F. Muell.","authors":"Leandro Silva de Oliveira, Douglas Machado Leite, Fabíola Magalhães Mendes, Letícia Vaz Molinari, Gilvano Ebling Brondani, Antônio Natal Gonçalves, Marcilio de Almeida","doi":"10.1007/s13205-024-04131-2","DOIUrl":"https://doi.org/10.1007/s13205-024-04131-2","url":null,"abstract":"<p><p>Micropropagation is an important tool for the propagation for recalcitrant species, like <i>Eucalyptus cloeziana.</i> This is a first reported about a complete study of the <i>E. cloeziana</i>, it includes the vegetative rescue protocol of mature trees, its micropropagation up to the implementation of a mini-garden and clonal micro-garden and evaluation of adventitious rooting of their propagules. The in vitro rejuvenation of <i>E. cloeziana</i> genotypes (03, 05, 06, 13 and 15), over 21 successive subcultures, was evaluated by comparing minicutting and microcutting techniques and the efficiency of this biotechnological tool for cloning of the mature trees. The results provide evidence of the in vitro rejuvenation occurring in the mature <i>E. cloeziana</i> trees during micropropagation, leading to increases in the multiplication ratios of the microstumps of three genotypes (03, 05 and 15). The survival and callogenesis percentages of the mini and microcuttings of <i>E. cloeziana</i> were higher than 80% upon exiting of the greenhouse (30-days old) in the three cutting times. The results suggesting that factors beyond tissue maturity influence the adventitious rooting of the <i>E. cloeziana</i> because minicuttings and microcuttings of the 05 and 13 elite genotypes exhibited rooting percentages lower than 20%. These findings provided a theoretical basis for realizing the micropropagation of the epicormic shoots of the mature trees and, subsequently, its in vitro rejuvenation by axillary bud proliferation.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"292"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanomaterial-enabled drug transport systems: a comprehensive exploration of current developments and future avenues in therapeutic delivery.","authors":"Shatabdi Basu, Pragnya Biswas, Mariya Anto, Nandini Singh, Koel Mukherjee","doi":"10.1007/s13205-024-04135-y","DOIUrl":"10.1007/s13205-024-04135-y","url":null,"abstract":"<p><p>Over the years, nanotechnology has gained popularity as a viable solution to address gene and drug delivery challenges over conventional methods. Extensive research has been conducted on nanosystems that consist of organic/inorganic materials, drugs, and its biocompatibility become the primary goal of improving drug delivery. Various surface modification methods help focus targeted and controlled drug release, further enabling multidrug delivery also. This newer technology ensures the stability of drugs that can unravel the mechanisms involved in cellular processes of disease development and its management. Tailored medication delivery provides benefits such as therapy, controlled release, and reduced adverse effects, which are especially important for controlling illnesses like cancer. However, multifunctional nanocarriers that possess high viscoelasticity, extended circulation half-life, biocompatibility, and biodegradability face some challenges and limitations too in human bodies. To produce a consistent therapeutic platform based on complex three-dimensional nanoparticles, careful design and engineering, thorough orthogonal analysis methods, and reproducible scale-up and manufacturing processes will be required in the future. Safety and effectiveness of nano-based drug delivery should be thoroughly investigated in preclinical and clinical trials, especially when considering biodistribution, targeting specific areas, and potential immunological toxicities. Overall, the current review article explores the advancements in nanotechnology, specific to nanomaterial-enabled drug delivery systems, carrier fabrication techniques and modifications, disease management, clinical research, applications, limitations, and future challenges. The work portrays how nanomedicine distribution affects healthcare with an emphasis on the developments in drug delivery techniques.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"289"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plant resources for immunonutrients and immunomodulators to combat infectious respiratory viral diseases: a review.","authors":"Sobha Kota, Anand Kumar Nelapati, Vayunandana Rao Govada","doi":"10.1007/s13205-024-04143-y","DOIUrl":"10.1007/s13205-024-04143-y","url":null,"abstract":"<p><p>Boosting the immune system has become a crucial aspect in the global battle against the COVID-19 pandemic and other similar infections to protect oneself against symptoms, especially in the prevention of viral infections of the lower respiratory tract. The importance of conducting more studies to create successful herbal formulations as infection prevention measures is emphasized in this review, which looks at the function of immune-boosting nutrients, medicinal plants, and herbal treatments. We reviewed and analyzed 207 studies published from 1946 to the present using reputable databases like Google Scholar, PubMed, and NCBI. The review examined 115 plant species in total and identified 12 key nutrients, including vitamins A, D, C, omega-3 fatty acids, iron, and zinc, while noting that four plant families, Rosaceae, Asteraceae, Amaryllidaceae, and Acanthaceae, show potential against respiratory infections like influenza, RSV, and SARS-CoV. To lower the risk of infection, it is recommended to consume nutritious meals that have immune-modulating qualities. Information on the bioactive components of medicinal herbs, spices, and plants that have been effective in treating respiratory viral infections and related conditions is compiled in this review, which highlights phytoactive substances with antibacterial and antiviral activity as effective modulators to lower the risk of infections. Furthermore, it is highlighted that ancient knowledge systems, like Ayurveda and Naturopathy, should be integrated to help develop new herbal formulations. To improve immunity and lessen vulnerability to serious respiratory infections, the results highlight the need for including immune-modulating foods and plant-based medicines into everyday routines.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"14 12","pages":"302"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}